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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TBX4

Z-value: 0.50

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Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
TBX4
ENSG00000121075.5 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg19_v2_chr17_+_59529743_59529798-0.232.2e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_73358594 3.57 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr9_-_75567962 2.45 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr11_-_5248294 1.58 ENST00000335295.4
HBB
hemoglobin, beta
chr13_-_36429763 1.41 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr3_-_66551397 1.38 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr3_-_66551351 1.31 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr20_+_44098346 1.27 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr11_+_86511549 1.22 ENST00000533902.2
PRSS23
protease, serine, 23
chr11_-_34535297 1.11 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr11_-_34535332 1.06 ENST00000257832.2
ENST00000429939.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr17_+_35849937 0.99 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr6_+_39760129 0.99 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr20_+_44098385 0.85 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr11_-_33913708 0.82 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr2_-_157189180 0.80 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_+_1940786 0.76 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chr1_+_114472222 0.75 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr2_-_61697862 0.70 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr1_+_114471809 0.69 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr1_+_114472481 0.68 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr17_-_7232585 0.68 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr1_+_16062820 0.67 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr5_-_74807418 0.63 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr11_-_85430204 0.62 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr12_-_90024360 0.60 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr11_-_85430163 0.59 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr15_+_41913690 0.57 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr11_+_86511569 0.54 ENST00000441050.1
PRSS23
protease, serine, 23
chr11_-_33891362 0.53 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_50451331 0.53 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr1_-_85930246 0.52 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_+_89402148 0.50 ENST00000560601.1
ACAN
aggrecan
chr1_+_26737292 0.49 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr5_+_74807581 0.47 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr11_+_61447845 0.46 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr1_+_114471972 0.45 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr1_+_26737253 0.44 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr11_-_85430088 0.42 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr16_+_2588012 0.42 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr15_+_92937144 0.41 ENST00000539113.1
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr8_+_123793633 0.41 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr1_+_27114418 0.39 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr4_-_140222358 0.38 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr18_-_53068911 0.38 ENST00000537856.3
TCF4
transcription factor 4
chr3_-_49459878 0.38 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr1_+_158325684 0.35 ENST00000368162.2
CD1E
CD1e molecule
chr1_+_95582881 0.34 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr14_+_93897272 0.34 ENST00000393151.2
UNC79
unc-79 homolog (C. elegans)
chr3_-_49459865 0.34 ENST00000427987.1
AMT
aminomethyltransferase
chr3_-_52443799 0.34 ENST00000470173.1
ENST00000296288.5
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr16_+_67596310 0.33 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr10_+_45406627 0.33 ENST00000389583.4
TMEM72
transmembrane protein 72
chr8_+_95907993 0.32 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr1_-_1009683 0.32 ENST00000453464.2
RNF223
ring finger protein 223
chr1_+_27114589 0.32 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr2_+_103089756 0.32 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr2_+_172864490 0.31 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr17_-_26220366 0.30 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr16_+_2587998 0.29 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr5_-_54281407 0.29 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr11_+_64073699 0.29 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr1_+_151584544 0.29 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chr11_-_118972575 0.28 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr2_-_111291587 0.28 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr17_+_30771279 0.28 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr3_-_93747425 0.28 ENST00000315099.2
STX19
syntaxin 19
chr16_+_2587965 0.27 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr9_+_71986182 0.27 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr14_-_65569244 0.27 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr4_+_160188889 0.26 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_-_39203519 0.26 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr11_-_6502534 0.25 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr5_+_56469843 0.25 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr11_-_133826852 0.25 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr1_-_182640988 0.25 ENST00000367556.1
RGS8
regulator of G-protein signaling 8
chr6_-_13487825 0.24 ENST00000603223.1
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_-_182641037 0.24 ENST00000483095.2
RGS8
regulator of G-protein signaling 8
chr6_+_30295036 0.23 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr2_-_160473114 0.23 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr1_-_226076843 0.22 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr7_-_150675372 0.21 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_-_6502580 0.21 ENST00000423813.2
ENST00000396777.3
ARFIP2
ADP-ribosylation factor interacting protein 2
chr7_-_105319536 0.20 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr11_-_114271139 0.20 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr20_+_11898507 0.20 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr3_+_142315225 0.20 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr1_-_182641367 0.20 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr3_+_63805017 0.20 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr11_-_111749767 0.20 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr11_-_129062093 0.19 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr6_+_30294612 0.19 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
TRIM39
tripartite motif containing 39
chr5_+_56469775 0.19 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr2_-_160472952 0.18 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr12_+_58148842 0.18 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr18_+_32073253 0.18 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr11_+_111749650 0.17 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr14_+_90864504 0.17 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr20_+_44657845 0.16 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chrX_-_19689106 0.16 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_111749878 0.16 ENST00000260257.4
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr17_-_61988556 0.16 ENST00000309894.5
ENST00000438387.2
ENST00000346606.6
ENST00000561003.1
ENST00000450719.3
ENST00000259003.10
CSHL1
chorionic somatomammotropin hormone-like 1
chr11_+_18344106 0.15 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr12_-_26278030 0.15 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr17_-_61996192 0.14 ENST00000392824.4
CSHL1
chorionic somatomammotropin hormone-like 1
chr5_-_34043310 0.14 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr13_+_115047097 0.13 ENST00000351487.5
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr22_-_41215328 0.13 ENST00000434185.1
ENST00000435456.2
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr3_+_134514093 0.13 ENST00000398015.3
EPHB1
EPH receptor B1
chr2_+_61108650 0.12 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_+_10131437 0.12 ENST00000587782.1
RDH8
retinol dehydrogenase 8 (all-trans)
chr5_+_56469939 0.12 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr15_+_60296421 0.12 ENST00000396057.4
FOXB1
forkhead box B1
chr11_+_111750206 0.11 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr1_+_228395755 0.11 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr7_+_97361218 0.11 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr11_-_128737259 0.10 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr11_-_128737163 0.10 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr10_-_99531709 0.10 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr1_-_37499726 0.10 ENST00000373091.3
ENST00000373093.4
GRIK3
glutamate receptor, ionotropic, kainate 3
chr7_+_97361388 0.09 ENST00000350485.4
ENST00000346867.4
TAC1
tachykinin, precursor 1
chrM_+_10053 0.08 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chrM_+_10758 0.08 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr16_+_85645007 0.08 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr9_+_136399929 0.07 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chrX_+_46771848 0.07 ENST00000218343.4
PHF16
jade family PHD finger 3
chr5_+_150040403 0.07 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr3_+_137728842 0.07 ENST00000183605.5
CLDN18
claudin 18
chr1_+_145507587 0.07 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr2_-_175869936 0.06 ENST00000409900.3
CHN1
chimerin 1
chr5_+_113697983 0.06 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chrX_+_46771711 0.06 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chr2_+_61108771 0.06 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr5_-_114515734 0.05 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr2_+_154728426 0.05 ENST00000392825.3
ENST00000434213.1
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr3_+_120626919 0.05 ENST00000273666.6
ENST00000471454.1
ENST00000472879.1
ENST00000497029.1
ENST00000492541.1
STXBP5L
syntaxin binding protein 5-like
chr12_-_18890940 0.05 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr11_-_74660159 0.05 ENST00000527087.1
ENST00000321448.8
ENST00000340360.6
XRRA1
X-ray radiation resistance associated 1
chr20_+_2517253 0.05 ENST00000358864.1
TMC2
transmembrane channel-like 2
chr2_+_202937972 0.05 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr12_-_7848364 0.05 ENST00000329913.3
GDF3
growth differentiation factor 3
chr15_-_58357932 0.04 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr6_+_32132360 0.04 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8
EGF-like-domain, multiple 8
chr6_-_13487784 0.04 ENST00000379287.3
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_+_206680879 0.04 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr9_-_117692697 0.03 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr14_+_78870030 0.03 ENST00000553631.1
ENST00000554719.1
NRXN3
neurexin 3
chr15_+_36994210 0.03 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr8_-_99954788 0.03 ENST00000523601.1
STK3
serine/threonine kinase 3
chr22_-_41215291 0.02 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr6_+_132873832 0.02 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr7_-_71801980 0.02 ENST00000329008.5
CALN1
calneuron 1
chr10_+_135050908 0.02 ENST00000325980.9
VENTX
VENT homeobox
chr16_-_67965756 0.02 ENST00000571044.1
ENST00000571605.1
CTRL
chymotrypsin-like
chr8_+_103563792 0.01 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr9_+_140032842 0.01 ENST00000371561.3
ENST00000315048.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr3_+_167453493 0.00 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr4_-_146859623 0.00 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 2.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.4 1.6 GO:0030185 nitric oxide transport(GO:0030185)
0.4 2.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.3 2.6 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.3 0.8 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.6 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.1 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 1.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.5 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 1.0 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.6 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.3 GO:0010216 maintenance of DNA methylation(GO:0010216) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 1.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0043132 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 3.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0061030 axon target recognition(GO:0007412) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 1.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0071638 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.7 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 2.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 1.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.3 1.6 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.8 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 0.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.7 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.6 GO:0097001 ceramide binding(GO:0097001)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.2 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.3 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation