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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TCF21

Z-value: 1.48

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
TCF21
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.096.4e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_205391178 9.32 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr22_+_38071615 7.79 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr1_+_171154347 6.59 ENST00000209929.7
ENST00000441535.1
FMO2
flavin containing monooxygenase 2 (non-functional)
chr17_-_7493390 6.44 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chrX_+_69509927 5.73 ENST00000374403.3
KIF4A
kinesin family member 4A
chr7_-_41742697 5.51 ENST00000242208.4
INHBA
inhibin, beta A
chr20_-_52790055 5.09 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr18_+_21529811 4.22 ENST00000588004.1
LAMA3
laminin, alpha 3
chr17_+_6347729 3.91 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr17_-_43025005 3.91 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr16_-_46655538 3.89 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr17_+_6347761 3.85 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr12_-_52845910 3.50 ENST00000252252.3
KRT6B
keratin 6B
chr5_-_59995921 3.46 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEPDC1B
DEP domain containing 1B
chr17_+_62223320 3.44 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr5_+_68463043 3.44 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr20_+_30327063 3.31 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr20_-_23030296 3.28 ENST00000377103.2
THBD
thrombomodulin
chr12_-_6960407 3.28 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr5_+_68462944 3.28 ENST00000506572.1
CCNB1
cyclin B1
chr11_+_33061543 3.24 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr20_-_54967187 3.18 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr5_+_68462837 3.12 ENST00000256442.5
CCNB1
cyclin B1
chr7_-_76255444 3.11 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr11_+_125496619 3.06 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr11_+_125496400 3.00 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr1_-_204135450 2.97 ENST00000272190.8
ENST00000367195.2
REN
renin
chr15_+_63354769 2.97 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr9_+_125137565 2.65 ENST00000373698.5
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr20_-_46415297 2.62 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr11_+_125496124 2.50 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr11_-_87908600 2.48 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr12_-_52585765 2.42 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr19_-_43702231 2.34 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr19_+_48216600 2.34 ENST00000263277.3
ENST00000538399.1
EHD2
EH-domain containing 2
chr13_-_20767037 2.31 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr5_-_16936340 2.30 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr19_+_16187085 2.29 ENST00000300933.4
TPM4
tropomyosin 4
chr15_+_63340858 2.19 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr2_-_234763147 2.17 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP
Holliday junction recognition protein
chr17_+_41476327 2.15 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr2_+_7017796 2.14 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr1_+_153600869 2.12 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr19_-_4535233 2.06 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr5_+_135364584 2.06 ENST00000442011.2
ENST00000305126.8
TGFBI
transforming growth factor, beta-induced, 68kDa
chr7_-_128045984 2.04 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr15_+_63340734 2.02 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr4_-_4543700 1.99 ENST00000505286.1
ENST00000306200.2
STX18
syntaxin 18
chr11_+_47270475 1.97 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr14_-_106830057 1.90 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr15_+_63340775 1.89 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr15_+_63340647 1.89 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chrX_-_106960285 1.88 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr17_+_39261584 1.87 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr22_+_44319619 1.86 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr19_+_11651942 1.84 ENST00000587087.1
CNN1
calponin 1, basic, smooth muscle
chr15_+_93447675 1.80 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr19_+_11546093 1.79 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr19_-_40324767 1.79 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr15_+_63340553 1.79 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr15_+_89787180 1.78 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI
Fanconi anemia, complementation group I
chr14_+_24099318 1.76 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr17_+_4736627 1.70 ENST00000355280.6
ENST00000347992.7
MINK1
misshapen-like kinase 1
chr19_+_16186903 1.65 ENST00000588507.1
TPM4
tropomyosin 4
chr16_+_18995249 1.63 ENST00000569532.1
ENST00000304381.5
TMC7
transmembrane channel-like 7
chr8_-_41522719 1.62 ENST00000335651.6
ANK1
ankyrin 1, erythrocytic
chr11_+_47270436 1.61 ENST00000395397.3
ENST00000405576.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr11_+_72975524 1.60 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr15_-_75017711 1.60 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr17_-_3417062 1.57 ENST00000570318.1
ENST00000541913.1
SPATA22
spermatogenesis associated 22
chr11_+_72975578 1.56 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr10_-_29923893 1.55 ENST00000355867.4
SVIL
supervillin
chr11_+_72975559 1.54 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr14_-_50154921 1.54 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr19_-_4831701 1.53 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr20_-_46415341 1.53 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr5_-_11589131 1.52 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr1_-_114429997 1.50 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr9_+_118950325 1.50 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chrX_+_17755563 1.49 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr11_-_102496063 1.47 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr19_+_35485682 1.44 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr7_-_99698338 1.42 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr6_-_30658745 1.41 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr11_-_1643368 1.37 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr8_+_66955648 1.36 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr8_-_92053212 1.35 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr1_-_85097431 1.35 ENST00000327308.3
C1orf180
chromosome 1 open reading frame 180
chr13_-_50510622 1.34 ENST00000378195.2
SPRYD7
SPRY domain containing 7
chr2_-_225811747 1.33 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr1_+_111772314 1.31 ENST00000466741.1
ENST00000477185.2
CHI3L2
chitinase 3-like 2
chr15_+_83776137 1.31 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr1_-_6550625 1.31 ENST00000377725.1
ENST00000340850.5
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr12_+_57828521 1.30 ENST00000309668.2
INHBC
inhibin, beta C
chr2_-_224702270 1.29 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr9_-_113761720 1.28 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr9_+_27109133 1.28 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr5_-_95158644 1.25 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr3_-_176915215 1.25 ENST00000457928.2
ENST00000422442.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_55013889 1.25 ENST00000343744.2
ENST00000371316.3
ACOT11
acyl-CoA thioesterase 11
chr1_+_78354297 1.24 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr7_-_44105158 1.24 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr11_-_5323226 1.23 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr6_-_11382478 1.22 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr12_+_122326662 1.22 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr2_-_17981462 1.21 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr17_+_19314505 1.21 ENST00000461366.1
RNF112
ring finger protein 112
chr1_-_228604328 1.21 ENST00000355586.4
ENST00000366698.2
ENST00000520264.1
ENST00000479800.1
ENST00000295033.3
TRIM17
tripartite motif containing 17
chr22_-_22307199 1.21 ENST00000397495.4
ENST00000263212.5
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr22_+_23264766 1.20 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr11_-_7847519 1.20 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr12_-_104443890 1.19 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2
glycosyltransferase 8 domain containing 2
chr16_-_31100284 1.19 ENST00000280606.6
PRSS53
protease, serine, 53
chr14_-_91282726 1.18 ENST00000328459.6
ENST00000357056.2
TTC7B
tetratricopeptide repeat domain 7B
chr5_-_179050660 1.18 ENST00000519056.1
ENST00000506721.1
ENST00000503105.1
ENST00000504348.1
ENST00000508103.1
ENST00000510431.1
ENST00000515158.1
ENST00000393432.4
ENST00000442819.2
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr22_-_23922410 1.17 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr13_-_50510434 1.17 ENST00000361840.3
SPRYD7
SPRY domain containing 7
chr17_-_7297833 1.15 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr20_-_1309809 1.15 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr12_+_113659234 1.13 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1
two pore segment channel 1
chr16_+_81678957 1.13 ENST00000398040.4
CMIP
c-Maf inducing protein
chr4_-_89152474 1.13 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr16_+_2022036 1.08 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr6_+_150070857 1.07 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr11_+_117103441 1.07 ENST00000531287.1
ENST00000531452.1
RNF214
ring finger protein 214
chr1_-_230513367 1.07 ENST00000321327.2
ENST00000525115.1
PGBD5
piggyBac transposable element derived 5
chr2_+_61244697 1.07 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
PEX13
peroxisomal biogenesis factor 13
chr17_-_72772462 1.04 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr2_+_192110199 1.03 ENST00000304164.4
MYO1B
myosin IB
chr2_+_33701286 1.02 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_-_143771799 1.02 ENST00000237283.8
ADAT2
adenosine deaminase, tRNA-specific 2
chr19_-_1650666 1.01 ENST00000588136.1
TCF3
transcription factor 3
chrX_+_48432892 1.00 ENST00000376759.3
ENST00000430348.2
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr11_-_14913190 0.97 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr6_-_25830785 0.97 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr6_-_26250835 0.97 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr12_+_69201923 0.96 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr17_+_71228793 0.95 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr22_-_23922448 0.95 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr3_+_101498269 0.94 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr1_-_248903150 0.93 ENST00000590317.1
LYPD8
LY6/PLAUR domain containing 8
chr15_-_65407524 0.92 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr4_-_153303658 0.90 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_+_1748798 0.89 ENST00000561626.1
ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr2_-_152590946 0.88 ENST00000172853.10
NEB
nebulin
chr4_+_37892682 0.88 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr7_+_20687017 0.87 ENST00000258738.6
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_-_179050066 0.87 ENST00000329433.6
ENST00000510411.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chrX_-_78622805 0.87 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr17_+_7341586 0.87 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr1_-_149889382 0.87 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr7_-_47988088 0.86 ENST00000289672.2
PKD1L1
polycystic kidney disease 1 like 1
chr1_-_9129735 0.85 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_-_46288917 0.85 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
DMWD
AC011530.4
dystrophia myotonica, WD repeat containing
Uncharacterized protein
chr11_+_6947720 0.83 ENST00000414517.2
ZNF215
zinc finger protein 215
chr11_-_114430570 0.83 ENST00000251921.2
NXPE1
neurexophilin and PC-esterase domain family, member 1
chr6_+_31554962 0.82 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr5_+_121647924 0.82 ENST00000414317.2
SNCAIP
synuclein, alpha interacting protein
chr8_-_55014415 0.81 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1
lysophospholipase I
chr21_-_33651324 0.81 ENST00000290130.3
MIS18A
MIS18 kinetochore protein A
chr6_+_31555045 0.81 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr2_-_228028829 0.80 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr11_-_104827425 0.79 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr15_-_67546963 0.79 ENST00000561452.1
ENST00000261880.5
AAGAB
alpha- and gamma-adaptin binding protein
chr12_+_112563335 0.79 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr19_+_57999079 0.78 ENST00000426954.2
ENST00000354197.4
ENST00000523882.1
ENST00000520540.1
ENST00000519310.1
ENST00000442920.2
ENST00000523312.1
ENST00000424930.2
ZNF419
zinc finger protein 419
chr18_+_55888767 0.78 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_-_106054952 0.77 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr18_+_3247779 0.76 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr6_+_31554779 0.76 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr19_+_57999101 0.76 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
ZNF419
zinc finger protein 419
chr7_-_132766818 0.75 ENST00000262570.5
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr1_-_150849174 0.75 ENST00000515192.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr3_-_81792780 0.75 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr11_-_117103208 0.74 ENST00000320934.3
ENST00000530269.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr18_+_3448455 0.74 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr8_+_38585704 0.74 ENST00000519416.1
ENST00000520615.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr19_-_4867665 0.73 ENST00000592528.1
ENST00000589494.1
ENST00000585479.1
ENST00000221957.4
PLIN3
perilipin 3
chr11_-_82997371 0.72 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr16_+_56703737 0.72 ENST00000569155.1
MT1H
metallothionein 1H
chr4_+_164415594 0.72 ENST00000509657.1
ENST00000358572.5
TMA16
translation machinery associated 16 homolog (S. cerevisiae)
chr4_+_123844225 0.71 ENST00000274008.4
SPATA5
spermatogenesis associated 5
chr8_+_91803695 0.71 ENST00000417640.2
NECAB1
N-terminal EF-hand calcium binding protein 1
chr18_+_158513 0.71 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr1_-_85100703 0.70 ENST00000370624.1
C1orf180
chromosome 1 open reading frame 180
chr14_-_93214915 0.68 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
LGMN
legumain
chr7_-_132766800 0.67 ENST00000542753.1
ENST00000448878.1
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr1_+_25870070 0.67 ENST00000374338.4
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr11_-_14913765 0.66 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr1_-_167522982 0.66 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr11_-_82997420 0.66 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr4_-_186347099 0.66 ENST00000505357.1
ENST00000264689.6
UFSP2
UFM1-specific peptidase 2
chr17_-_8093471 0.65 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr10_+_1102303 0.65 ENST00000381329.1
WDR37
WD repeat domain 37
chrX_+_78426469 0.65 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr22_+_44351301 0.65 ENST00000350028.4
SAMM50
SAMM50 sorting and assembly machinery component
chr1_-_243326612 0.65 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr6_-_27835357 0.64 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr17_-_4167142 0.63 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr2_+_90273679 0.63 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:0046680 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
2.1 6.4 GO:0048627 myoblast development(GO:0048627)
1.8 5.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.7 8.7 GO:0002317 plasma cell differentiation(GO:0002317)
1.7 5.1 GO:0042369 vitamin D catabolic process(GO:0042369)
1.6 12.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
1.4 8.6 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.2 3.6 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.1 3.2 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
1.0 4.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.0 6.2 GO:0070995 NADPH oxidation(GO:0070995)
0.7 2.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.5 1.6 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.5 3.1 GO:0035803 egg coat formation(GO:0035803)
0.5 2.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.5 3.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.5 1.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.4 2.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.4 1.6 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.4 1.6 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.4 6.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.4 1.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.4 2.5 GO:1903232 melanosome assembly(GO:1903232)
0.3 2.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 2.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 4.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 1.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.0 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3 0.9 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.3 1.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.3 3.9 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.3 1.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 0.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 0.7 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.2 0.9 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.2 1.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.5 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 0.8 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.2 0.9 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.2 2.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.2 0.9 GO:0048749 compound eye development(GO:0048749)
0.2 0.9 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 0.7 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.2 0.5 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 1.2 GO:0060613 fat pad development(GO:0060613)
0.2 1.9 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.2 0.8 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 2.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 4.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 1.0 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.6 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 1.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 2.1 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.8 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.3 GO:0051775 response to redox state(GO:0051775)
0.1 1.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.1 GO:0030091 protein repair(GO:0030091)
0.1 0.9 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 3.5 GO:0007398 ectoderm development(GO:0007398)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.9 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 1.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.4 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 1.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 4.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 0.6 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 2.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.3 GO:1904647 response to rotenone(GO:1904647)
0.1 3.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.5 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 1.0 GO:0002097 tRNA wobble base modification(GO:0002097)
0.1 1.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 1.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 3.9 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.1 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 1.5 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.6 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.4 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 1.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 1.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 2.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.3 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 1.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.8 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 4.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 2.3 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 2.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.2 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 2.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.6 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 2.3 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 1.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 4.2 GO:0061572 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.3 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 4.4 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 1.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:0030865 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.4 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.0 0.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 2.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.6 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 4.0 GO:0007015 actin filament organization(GO:0007015)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.0 0.7 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.9 GO:0007267 cell-cell signaling(GO:0007267)
0.0 1.8 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.8 5.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.9 16.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.8 3.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.5 4.2 GO:0005610 laminin-5 complex(GO:0005610)
0.5 2.5 GO:0031905 early endosome lumen(GO:0031905)
0.4 3.9 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.3 1.5 GO:0036449 microtubule minus-end(GO:0036449)
0.3 3.3 GO:0043203 axon hillock(GO:0043203)
0.3 1.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.2 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 1.4 GO:0061617 MICOS complex(GO:0061617)
0.2 2.3 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 8.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.3 GO:0032433 filopodium tip(GO:0032433)
0.1 3.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 8.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.4 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 8.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 1.5 GO:0097342 ripoptosome(GO:0097342)
0.1 3.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 7.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 2.9 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 11.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 4.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.5 GO:0097223 sperm part(GO:0097223)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.0 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 5.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 8.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0045202 synapse(GO:0045202)
0.0 2.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0016592 mediator complex(GO:0016592) ciliary base(GO:0097546)
0.0 3.2 GO:0030027 lamellipodium(GO:0030027)
0.0 1.7 GO:0030018 Z disc(GO:0030018)
0.0 1.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0005795 Golgi stack(GO:0005795)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 2.7 GO:0060076 excitatory synapse(GO:0060076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0030395 lactose binding(GO:0030395)
1.8 5.5 GO:0070699 type II activin receptor binding(GO:0070699)
1.4 8.6 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.4 9.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.3 6.7 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.8 1.6 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.8 4.7 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.7 3.6 GO:0032810 sterol response element binding(GO:0032810)
0.7 4.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 5.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.7 2.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.7 3.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.6 2.5 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.5 2.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 3.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 1.8 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.3 1.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.3 3.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 3.1 GO:0032190 acrosin binding(GO:0032190)
0.3 1.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3 0.9 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.3 1.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 2.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 0.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 2.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 1.9 GO:0043426 MRF binding(GO:0043426)
0.2 1.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.8 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 1.3 GO:0035473 lipase binding(GO:0035473)
0.2 1.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 0.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 19.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 5.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.6 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 1.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 2.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 3.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 1.3 GO:0004568 chitinase activity(GO:0004568)
0.1 2.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 1.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 1.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 4.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.2 GO:0005549 odorant binding(GO:0005549)
0.1 3.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 4.2 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 3.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 2.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 4.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 4.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 8.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.8 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 16.3 PID PLK1 PATHWAY PLK1 signaling events
0.2 4.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 9.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.1 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.7 PID SHP2 PATHWAY SHP2 signaling
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 18.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.5 6.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 17.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 4.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 3.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 7.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 5.7 REACTOME KINESINS Genes involved in Kinesins
0.1 2.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 10.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 4.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 2.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 4.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 4.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 4.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import