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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TCF7

Z-value: 0.63

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Transcription factors associated with TCF7

Gene Symbol Gene ID Gene Info
TCF7
ENSG00000081059.15 transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7hg19_v2_chr5_+_133450365_1334504440.561.3e-03Click!

Activity profile of TCF7 motif

Sorted Z-values of TCF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_116937636 2.29 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr17_+_68100989 2.18 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_154863264 2.10 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1
HTR5A antisense RNA 1
chr10_-_61513201 2.07 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr6_+_112408768 1.75 ENST00000368656.2
ENST00000604268.1
FAM229B
family with sequence similarity 229, member B
chr2_-_86564776 1.69 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr20_+_31823792 1.67 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr14_+_74486043 1.64 ENST00000464394.1
ENST00000394009.3
CCDC176
coiled-coil domain containing 176
chr6_-_29527702 1.51 ENST00000377050.4
UBD
ubiquitin D
chr12_-_58329819 1.50 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr3_-_197676740 1.50 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
IQCG
IQ motif containing G
chr2_+_172378757 1.44 ENST00000409484.1
ENST00000321348.4
ENST00000375252.3
CYBRD1
cytochrome b reductase 1
chr11_-_8615507 1.35 ENST00000431279.2
ENST00000418597.1
STK33
serine/threonine kinase 33
chr17_-_63556414 1.26 ENST00000585045.1
AXIN2
axin 2
chr17_-_63557309 1.23 ENST00000580513.1
AXIN2
axin 2
chr1_-_151345159 1.14 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
SELENBP1
selenium binding protein 1
chr7_+_142829162 1.11 ENST00000291009.3
PIP
prolactin-induced protein
chr12_-_58329888 1.07 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr20_-_39317868 1.03 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr1_+_183774240 1.00 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr2_-_217560248 0.94 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr10_-_104211294 0.93 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr22_-_42336209 0.90 ENST00000472374.2
CENPM
centromere protein M
chrX_-_117119243 0.88 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr11_-_8615720 0.88 ENST00000358872.3
ENST00000454443.2
STK33
serine/threonine kinase 33
chr11_-_8615488 0.87 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33
serine/threonine kinase 33
chr15_-_93632421 0.87 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr6_+_52285046 0.84 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr1_+_244515930 0.82 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr5_+_140165876 0.81 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr6_+_159084188 0.79 ENST00000367081.3
SYTL3
synaptotagmin-like 3
chr11_+_120039685 0.79 ENST00000530303.1
ENST00000319763.1
AP000679.2
Uncharacterized protein
chr2_-_160761179 0.78 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
LY75
LY75-CD302
lymphocyte antigen 75
LY75-CD302 readthrough
chr11_-_62474803 0.75 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr15_-_48470544 0.75 ENST00000267836.6
MYEF2
myelin expression factor 2
chr4_-_23735183 0.74 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr10_+_7745232 0.73 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_-_14992264 0.69 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr17_-_56065484 0.69 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr22_+_39052632 0.67 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr12_-_10151773 0.66 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr16_-_81110683 0.65 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46
chromosome 16 open reading frame 46
chr22_+_24105394 0.65 ENST00000305199.5
ENST00000382821.3
C22orf15
chromosome 22 open reading frame 15
chr11_+_100862811 0.65 ENST00000303130.2
TMEM133
transmembrane protein 133
chr1_-_182641367 0.63 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr17_+_79953310 0.61 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_-_25702669 0.60 ENST00000446840.1
AC003090.1
AC003090.1
chr3_-_113160334 0.60 ENST00000393845.2
ENST00000295868.2
WDR52
WD repeat domain 52
chr15_-_52043722 0.59 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr6_-_161695042 0.59 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr14_+_76452090 0.59 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
IFT43
intraflagellar transport 43 homolog (Chlamydomonas)
chr4_+_40751914 0.57 ENST00000381782.2
ENST00000316607.5
NSUN7
NOP2/Sun domain family, member 7
chr8_+_133879193 0.57 ENST00000377869.1
ENST00000220616.4
TG
thyroglobulin
chr2_+_69240302 0.56 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr3_+_118865028 0.55 ENST00000460150.1
C3orf30
chromosome 3 open reading frame 30
chr12_-_49582593 0.55 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr7_+_23286182 0.55 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr11_+_46740730 0.54 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr17_+_53343577 0.54 ENST00000573945.1
HLF
hepatic leukemia factor
chr1_+_200993071 0.54 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr2_-_238499303 0.52 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr1_-_32801825 0.51 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr16_-_73082274 0.49 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr17_+_31254892 0.49 ENST00000394642.3
ENST00000579849.1
TMEM98
transmembrane protein 98
chr3_-_167813672 0.49 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr17_+_26698677 0.49 ENST00000457710.3
SARM1
sterile alpha and TIR motif containing 1
chr6_-_161695074 0.47 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr11_+_134144139 0.47 ENST00000389887.5
GLB1L3
galactosidase, beta 1-like 3
chr19_+_13135386 0.47 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_8615687 0.46 ENST00000534493.1
ENST00000422559.2
STK33
serine/threonine kinase 33
chrX_-_15332665 0.46 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr11_-_76155618 0.46 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr1_-_173991434 0.45 ENST00000367696.2
RC3H1
ring finger and CCCH-type domains 1
chr12_-_8043736 0.45 ENST00000539924.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr15_+_75287861 0.42 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5
secretory carrier membrane protein 5
chr21_-_32185570 0.42 ENST00000329621.4
KRTAP8-1
keratin associated protein 8-1
chr12_+_108523133 0.42 ENST00000547525.1
WSCD2
WSC domain containing 2
chr8_+_36641842 0.41 ENST00000523973.1
ENST00000399881.3
KCNU1
potassium channel, subfamily U, member 1
chr1_+_145470504 0.41 ENST00000323397.4
ANKRD34A
ankyrin repeat domain 34A
chr18_+_6729698 0.41 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr1_+_162351503 0.40 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr10_-_116444371 0.40 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr3_-_167813132 0.40 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr19_+_13134772 0.39 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_+_171561127 0.39 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr6_+_64346386 0.39 ENST00000509330.1
PHF3
PHD finger protein 3
chr11_-_108422926 0.38 ENST00000428840.1
ENST00000526312.1
EXPH5
exophilin 5
chr11_-_76155700 0.36 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr2_-_238499337 0.36 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr19_+_12273866 0.35 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136
zinc finger protein 136
chr2_+_10183651 0.35 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr11_-_111383064 0.35 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
BTG4
B-cell translocation gene 4
chr6_-_25874440 0.35 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr1_+_244998602 0.35 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr10_-_62332357 0.34 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_+_55086703 0.33 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR
epidermal growth factor receptor
chr22_+_29279552 0.33 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr8_-_6914251 0.33 ENST00000330590.2
DEFA5
defensin, alpha 5, Paneth cell-specific
chr9_-_21368075 0.32 ENST00000449498.1
IFNA13
interferon, alpha 13
chr10_+_6622345 0.31 ENST00000445427.1
ENST00000455810.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr2_-_231989808 0.31 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr7_-_36406750 0.31 ENST00000453212.1
ENST00000415803.2
ENST00000440378.1
ENST00000431396.1
ENST00000317020.6
ENST00000436884.1
KIAA0895
KIAA0895
chr8_+_56792377 0.31 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_145470383 0.31 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr18_-_5895954 0.30 ENST00000581347.2
TMEM200C
transmembrane protein 200C
chr22_+_29168652 0.30 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr8_-_119964434 0.30 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr11_-_85430204 0.29 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr6_-_11807277 0.29 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr22_-_47134077 0.29 ENST00000541677.1
ENST00000216264.8
CERK
ceramide kinase
chr11_-_85430163 0.29 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr1_-_182642017 0.29 ENST00000367557.4
ENST00000258302.4
RGS8
regulator of G-protein signaling 8
chr10_+_96698406 0.29 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr12_+_121131970 0.28 ENST00000535656.1
MLEC
malectin
chr5_+_43603229 0.28 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr8_+_56792355 0.28 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr4_-_74486347 0.28 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr5_+_43602750 0.27 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr3_+_138067521 0.27 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr1_-_149900122 0.27 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr1_-_11107280 0.27 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr4_-_100484825 0.27 ENST00000273962.3
ENST00000514547.1
ENST00000455368.2
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr12_-_3982511 0.27 ENST00000427057.2
ENST00000228820.4
PARP11
poly (ADP-ribose) polymerase family, member 11
chr17_+_79679369 0.26 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr12_-_55378452 0.26 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr17_+_79679299 0.26 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr1_+_20208870 0.26 ENST00000375120.3
OTUD3
OTU domain containing 3
chr4_+_95972822 0.25 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_62785054 0.25 ENST00000371153.4
KANK4
KN motif and ankyrin repeat domains 4
chr3_+_169490834 0.25 ENST00000392733.1
MYNN
myoneurin
chr17_+_72428218 0.25 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr15_+_63414760 0.24 ENST00000557972.1
LACTB
lactamase, beta
chr12_-_96390108 0.24 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr17_-_26989136 0.24 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr1_-_200992827 0.24 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr7_+_94023873 0.24 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr21_+_33784670 0.24 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr2_+_46926326 0.24 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr3_+_118864991 0.23 ENST00000295622.1
C3orf30
chromosome 3 open reading frame 30
chr19_-_56826157 0.23 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr19_-_48389651 0.23 ENST00000222002.3
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr6_-_15548591 0.23 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr13_+_30002741 0.23 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr22_-_26908343 0.23 ENST00000407431.1
ENST00000455080.1
ENST00000418876.1
ENST00000440258.1
ENST00000407148.1
ENST00000420242.1
ENST00000405938.1
ENST00000407690.1
TFIP11
tuftelin interacting protein 11
chr3_+_14989186 0.23 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr3_+_36421826 0.23 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr5_-_79287060 0.22 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr17_+_67498538 0.22 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_-_33774944 0.22 ENST00000532057.1
ENST00000531080.1
FBXO3
F-box protein 3
chrX_-_13956737 0.22 ENST00000454189.2
GPM6B
glycoprotein M6B
chr13_+_102104980 0.22 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_133405409 0.21 ENST00000545875.1
ENST00000456883.2
GOLGA3
golgin A3
chr2_+_159651821 0.21 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr12_-_46385811 0.21 ENST00000419565.2
SCAF11
SR-related CTD-associated factor 11
chr7_+_99613195 0.21 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr15_+_74466012 0.21 ENST00000249842.3
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr10_+_7745303 0.20 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_85430088 0.20 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chrX_-_55020511 0.20 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_28527152 0.20 ENST00000321830.5
AL353354.1
Uncharacterized protein
chr1_-_213020991 0.20 ENST00000332912.3
C1orf227
chromosome 1 open reading frame 227
chr3_-_125775629 0.20 ENST00000383598.2
SLC41A3
solute carrier family 41, member 3
chr9_-_19033237 0.20 ENST00000380530.1
ENST00000542071.1
FAM154A
family with sequence similarity 154, member A
chr9_-_19033185 0.20 ENST00000380534.4
FAM154A
family with sequence similarity 154, member A
chr21_-_31538971 0.19 ENST00000286808.3
CLDN17
claudin 17
chr15_+_52043758 0.19 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr1_+_150229554 0.19 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr10_+_96522361 0.19 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr3_-_120068143 0.18 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr9_-_125675576 0.18 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr8_-_17579726 0.18 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr4_+_1873155 0.18 ENST00000507820.1
ENST00000514045.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr9_-_127533519 0.18 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr19_+_21579908 0.18 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr6_+_43457317 0.18 ENST00000438588.2
TJAP1
tight junction associated protein 1 (peripheral)
chr22_+_31742875 0.18 ENST00000504184.2
AC005003.1
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chrX_+_54835493 0.18 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr2_+_232573208 0.18 ENST00000409115.3
PTMA
prothymosin, alpha
chr6_-_62996066 0.17 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr15_-_44486632 0.17 ENST00000484674.1
FRMD5
FERM domain containing 5
chr6_-_112575838 0.17 ENST00000455073.1
LAMA4
laminin, alpha 4
chr9_-_130639997 0.17 ENST00000373176.1
AK1
adenylate kinase 1
chr6_-_112408661 0.17 ENST00000368662.5
TUBE1
tubulin, epsilon 1
chr5_-_36301984 0.16 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr3_-_47622282 0.16 ENST00000383738.2
ENST00000264723.4
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr8_-_90996459 0.16 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr3_+_45984947 0.16 ENST00000304552.4
CXCR6
chemokine (C-X-C motif) receptor 6
chr8_-_124279627 0.16 ENST00000357082.4
ZHX1-C8ORF76
ZHX1-C8ORF76 readthrough
chr10_+_52750930 0.15 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chr5_+_175740083 0.15 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr11_-_122930121 0.15 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr4_+_56815102 0.15 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr18_+_12407895 0.15 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr7_+_29234101 0.15 ENST00000435288.2
CHN2
chimerin 2
chr3_+_35681081 0.15 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_-_16840820 0.15 ENST00000450569.1
AGR2
anterior gradient 2
chr12_+_112204691 0.15 ENST00000416293.3
ENST00000261733.2
ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr12_-_67197760 0.15 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr8_-_139926236 0.14 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr17_+_48610074 0.14 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.4 2.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.3 1.0 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 0.9 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.3 1.5 GO:0070842 aggresome assembly(GO:0070842)
0.2 0.6 GO:0070666 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 0.6 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 0.5 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 1.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.5 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.3 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 1.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.5 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 2.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.5 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0071288 T-helper 1 cell lineage commitment(GO:0002296) cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.2 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.9 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 2.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0001534 radial spoke(GO:0001534)
0.2 1.5 GO:0002177 manchette(GO:0002177)
0.1 2.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 1.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.2 1.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 0.6 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 0.5 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 2.5 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.1 GO:0008430 selenium binding(GO:0008430)
0.1 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.5 GO:0070628 proteasome binding(GO:0070628)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.1 GO:0019864 IgG binding(GO:0019864)
0.1 0.3 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation