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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TEAD4

Z-value: 0.82

Motif logo

Transcription factors associated with TEAD4

Gene Symbol Gene ID Gene Info
ENSG00000197905.4 TEA domain transcription factor 4

Activity-expression correlation:

Activity profile of TEAD4 motif

Sorted Z-values of TEAD4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_110723134 6.85 ENST00000510800.1
ENST00000512148.1
complement factor I
chr4_-_110723335 5.24 ENST00000394634.2
complement factor I
chr4_-_110723194 5.17 ENST00000394635.3
complement factor I
chr9_-_34397800 4.67 ENST00000297623.2
chromosome 9 open reading frame 24
chr4_-_149365827 4.03 ENST00000344721.4
nuclear receptor subfamily 3, group C, member 2
chr4_+_70861647 3.91 ENST00000246895.4
ENST00000381060.2
statherin
chr1_-_207119738 3.83 ENST00000356495.4
polymeric immunoglobulin receptor
chr6_+_131958436 2.34 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr10_-_61513146 2.13 ENST00000430431.1
long intergenic non-protein coding RNA 948
chr6_-_76782371 1.97 ENST00000369950.3
ENST00000369963.3
interphotoreceptor matrix proteoglycan 1
chr1_-_60392452 1.67 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr12_+_20963647 1.62 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr4_+_41614909 1.59 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr10_-_61513201 1.58 ENST00000414264.1
ENST00000594536.1
long intergenic non-protein coding RNA 948
chr11_-_63376013 1.58 ENST00000540943.1
phospholipase A2, group XVI
chr3_-_52486841 1.58 ENST00000496590.1
troponin C type 1 (slow)
chr3_-_137834436 1.56 ENST00000327532.2
ENST00000467030.1
DAZ interacting zinc finger protein 1-like
chr12_+_20963632 1.56 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr5_+_140261703 1.55 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr20_-_7921090 1.46 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr6_-_52705641 1.43 ENST00000370989.2
glutathione S-transferase alpha 5
chr6_-_134639180 1.40 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr20_+_43160458 1.38 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr5_-_124081008 1.37 ENST00000306315.5
zinc finger protein 608
chr12_-_131200810 1.37 ENST00000536002.1
ENST00000544034.1
RIMS binding protein 2
RP11-662M24.2
chr19_+_35630022 1.36 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr19_+_35630344 1.31 ENST00000455515.2
FXYD domain containing ion transport regulator 1
chr8_-_27115931 1.31 ENST00000523048.1
stathmin-like 4
chr7_+_23719749 1.29 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
family with sequence similarity 221, member A
chr1_+_244214577 1.27 ENST00000358704.4
zinc finger and BTB domain containing 18
chr12_+_41831485 1.26 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr19_+_35630628 1.23 ENST00000588715.1
ENST00000588607.1
FXYD domain containing ion transport regulator 1
chr11_+_17316870 1.21 ENST00000458064.2
nucleobindin 2
chr12_+_86268065 1.16 ENST00000551529.1
ENST00000256010.6
neurotensin
chr22_-_42765174 1.14 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1
chr6_+_122720681 1.13 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr4_+_36283213 1.11 ENST00000357504.3
death domain containing 1
chr4_-_100356844 1.10 ENST00000437033.2
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_-_62001982 1.09 ENST00000409186.1
protocadherin 20
chr1_-_227505289 1.09 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr7_-_37024665 1.09 ENST00000396040.2
engulfment and cell motility 1
chr6_-_152489484 1.07 ENST00000354674.4
ENST00000539504.1
spectrin repeat containing, nuclear envelope 1
chr6_+_109169591 1.06 ENST00000368972.3
ENST00000392644.4
armadillo repeat containing 2
chr4_-_186317034 1.05 ENST00000505916.1
LRP2 binding protein
chr6_-_109330702 1.03 ENST00000356644.7
sestrin 1
chr7_+_116660246 0.98 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
suppression of tumorigenicity 7
chr6_-_32634425 0.96 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
major histocompatibility complex, class II, DQ beta 1
chr11_-_59633951 0.93 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr5_-_150603679 0.92 ENST00000355417.2
coiled-coil domain containing 69
chr2_-_48468122 0.89 ENST00000447571.1
AC079807.4
chr5_-_41261540 0.89 ENST00000263413.3
complement component 6
chr11_-_6440624 0.88 ENST00000311051.3
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr1_+_171283331 0.84 ENST00000367749.3
flavin containing monooxygenase 4
chr18_-_3219847 0.81 ENST00000261606.7
myomesin 1
chr16_+_53241854 0.80 ENST00000565803.1
chromodomain helicase DNA binding protein 9
chr6_+_46761118 0.80 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr18_+_55862622 0.80 ENST00000456173.2
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_-_154928562 0.79 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr14_-_89883412 0.79 ENST00000557258.1
forkhead box N3
chr1_+_43735678 0.79 ENST00000432792.2
transmembrane protein 125
chr12_+_56511943 0.78 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr2_+_38893208 0.76 ENST00000410063.1
galactose mutarotase (aldose 1-epimerase)
chr10_+_93683519 0.76 ENST00000265990.6
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
chr3_-_11685345 0.76 ENST00000430365.2
vestigial like 4 (Drosophila)
chr1_+_43735646 0.74 ENST00000439858.1
transmembrane protein 125
chr19_+_17403413 0.71 ENST00000595444.1
ENST00000600434.1
mitochondrial ribosomal protein L34
chr9_+_2029019 0.68 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_109554386 0.67 ENST00000338432.7
acetyl-CoA carboxylase beta
chr1_-_156252590 0.66 ENST00000361813.5
ENST00000368267.5
SMG5 nonsense mediated mRNA decay factor
chr4_+_41614720 0.64 ENST00000509277.1
LIM and calponin homology domains 1
chr1_-_39339777 0.63 ENST00000397572.2
MYC binding protein
chr1_-_240906911 0.63 ENST00000431139.2
RP11-80B9.4
chr9_-_15472730 0.63 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr4_+_120056939 0.63 ENST00000307128.5
myozenin 2
chr6_+_153552455 0.61 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr1_+_61547894 0.61 ENST00000403491.3
nuclear factor I/A
chr7_+_152456829 0.61 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ARP3 actin-related protein 3 homolog B (yeast)
chr3_+_132316081 0.60 ENST00000249887.2
atypical chemokine receptor 4
chr7_-_32529973 0.60 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_32582293 0.58 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr5_-_111093167 0.58 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr2_-_105882585 0.57 ENST00000595531.1
LOC644617 protein; Uncharacterized protein
chr19_+_10541462 0.56 ENST00000293683.5
phosphodiesterase 4A, cAMP-specific
chr18_-_3220106 0.55 ENST00000356443.4
ENST00000400569.3
myomesin 1
chr15_+_59730348 0.54 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr17_+_38219063 0.53 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
thyroid hormone receptor, alpha
chr11_-_79151695 0.52 ENST00000278550.7
teneurin transmembrane protein 4
chr14_-_75530693 0.51 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
acylphosphatase 1, erythrocyte (common) type
chr3_+_111805182 0.49 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
chromosome 3 open reading frame 52
chr12_+_10460549 0.47 ENST00000543420.1
ENST00000543777.1
killer cell lectin-like receptor subfamily D, member 1
chr16_-_73093597 0.47 ENST00000397992.5
zinc finger homeobox 3
chr3_+_138327417 0.47 ENST00000338446.4
Fas apoptotic inhibitory molecule
chrX_-_10588595 0.46 ENST00000423614.1
ENST00000317552.4
midline 1 (Opitz/BBB syndrome)
chr9_-_33402506 0.46 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
aquaporin 7
chr12_-_58220078 0.45 ENST00000549039.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr2_-_196933536 0.44 ENST00000312428.6
ENST00000410072.1
dynein, axonemal, heavy chain 7
chr8_+_24151553 0.44 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr6_-_45983581 0.44 ENST00000339561.6
chloride intracellular channel 5
chr1_+_154229547 0.44 ENST00000428595.1
ubiquitin associated protein 2-like
chr6_+_25754927 0.44 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr11_+_10476851 0.43 ENST00000396553.2
adenosine monophosphate deaminase 3
chr10_-_13276329 0.43 ENST00000378681.3
ENST00000463405.2
upper zone of growth plate and cartilage matrix associated
chrX_-_10588459 0.43 ENST00000380782.2
midline 1 (Opitz/BBB syndrome)
chr5_+_53751445 0.43 ENST00000302005.1
heat shock 27kDa protein 3
chr19_+_37837185 0.43 ENST00000541583.2
HKR1, GLI-Kruppel zinc finger family member
chr4_+_40337340 0.43 ENST00000310169.2
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr14_+_68286478 0.42 ENST00000487861.1
RAD51 paralog B
chr13_+_78315295 0.42 ENST00000351546.3
SLAIN motif family, member 1
chr8_-_70745575 0.42 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr10_-_52008313 0.42 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr3_+_123813509 0.42 ENST00000460856.1
ENST00000240874.3
kalirin, RhoGEF kinase
chr1_+_109256067 0.41 ENST00000271311.2
fibronectin type III domain containing 7
chr22_+_46449674 0.41 ENST00000381051.2
hsa-mir-4763
chr4_+_78804393 0.41 ENST00000502384.1
mitochondrial ribosomal protein L1
chr1_+_164528866 0.40 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr9_+_42671887 0.40 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr19_+_9361606 0.40 ENST00000456448.1
olfactory receptor, family 7, subfamily E, member 24
chr1_+_236557569 0.40 ENST00000334232.4
EDAR-associated death domain
chr10_-_62149433 0.40 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr8_+_24151620 0.40 ENST00000437154.2
ADAM metallopeptidase domain 28
chr1_+_241695424 0.39 ENST00000366558.3
ENST00000366559.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr10_+_123923205 0.39 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr11_+_60223312 0.38 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr19_-_19144243 0.38 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr15_+_81475047 0.37 ENST00000559388.1
interleukin 16
chr8_+_67405755 0.36 ENST00000521495.1
chromosome 8 open reading frame 46
chr7_-_16872932 0.36 ENST00000419572.2
ENST00000412973.1
anterior gradient 2
chr2_-_99279928 0.36 ENST00000414521.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_-_59249732 0.35 ENST00000371222.2
jun proto-oncogene
chr15_-_20193370 0.35 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr12_-_91539918 0.35 ENST00000548218.1
decorin
chr3_-_12587055 0.35 ENST00000564146.3
chromosome 3 open reading frame 83
chrX_-_77914825 0.34 ENST00000321110.1
zinc finger, CCHC domain containing 5
chr7_-_150777949 0.34 ENST00000482571.1
Fas-activated serine/threonine kinase
chr6_-_152958521 0.33 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
spectrin repeat containing, nuclear envelope 1
chr11_-_10590238 0.33 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1
chr17_+_17685422 0.32 ENST00000395774.1
retinoic acid induced 1
chr11_-_71639670 0.32 ENST00000533047.1
ENST00000529844.1
Putative short transient receptor potential channel 2-like protein
chr2_-_231989808 0.32 ENST00000258400.3
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr3_+_197518100 0.32 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
leucine-rich repeats and calponin homology (CH) domain containing 3
chr8_+_50824233 0.32 ENST00000522124.1
syntrophin, gamma 1
chr15_+_72947079 0.31 ENST00000421285.3
golgin A6 family, member B
chr9_+_90497741 0.31 ENST00000325643.5
SPATA31 subfamily E, member 1
chr7_-_116963334 0.31 ENST00000265441.3
wingless-type MMTV integration site family member 2
chr16_+_4364762 0.31 ENST00000262366.3
GLIS family zinc finger 2
chr10_+_47894572 0.31 ENST00000355876.5
family with sequence similarity 21, member B
chr12_-_49393092 0.30 ENST00000421952.2
dendrin
chr5_+_173472607 0.29 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr19_+_19144384 0.29 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr19_+_37825526 0.29 ENST00000592768.1
ENST00000591417.1
ENST00000585623.1
ENST00000592168.1
ENST00000591391.1
ENST00000392153.3
ENST00000589392.1
ENST00000324411.4
HKR1, GLI-Kruppel zinc finger family member
chr16_+_30386098 0.28 ENST00000322861.7
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_20251744 0.28 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr16_-_46797149 0.27 ENST00000536476.1
myosin light chain kinase 3
chr4_-_26492076 0.27 ENST00000295589.3
cholecystokinin A receptor
chr1_+_164529004 0.27 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
pre-B-cell leukemia homeobox 1
chr9_+_71944241 0.27 ENST00000257515.8
family with sequence similarity 189, member A2
chr15_-_52263937 0.26 ENST00000315141.5
ENST00000299601.5
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr20_-_3767324 0.26 ENST00000379751.4
centromere protein B, 80kDa
chr2_+_238768187 0.26 ENST00000254661.4
ENST00000409726.1
receptor (G protein-coupled) activity modifying protein 1
chr1_-_79472365 0.26 ENST00000370742.3
EGF, latrophilin and seven transmembrane domain containing 1
chr14_+_78870030 0.26 ENST00000553631.1
ENST00000554719.1
neurexin 3
chr2_-_119605253 0.25 ENST00000295206.6
engrailed homeobox 1
chr15_-_83224682 0.25 ENST00000562833.1
RP11-152F13.10
chr15_-_72563585 0.24 ENST00000287196.9
ENST00000260376.7
poly (ADP-ribose) polymerase family, member 6
chr3_+_123813543 0.24 ENST00000360013.3
kalirin, RhoGEF kinase
chr11_+_60223225 0.24 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr13_-_46679185 0.24 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr20_+_33814457 0.24 ENST00000246186.6
matrix metallopeptidase 24 (membrane-inserted)
chr8_-_114389353 0.23 ENST00000343508.3
CUB and Sushi multiple domains 3
chr13_+_113760098 0.23 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
coagulation factor VII (serum prothrombin conversion accelerator)
chr2_-_233641265 0.23 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
potassium inwardly-rectifying channel, subfamily J, member 13
chr17_+_47865917 0.22 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
K(lysine) acetyltransferase 7
chr13_-_46679144 0.22 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr7_-_92777606 0.21 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr18_+_6834472 0.21 ENST00000581099.1
ENST00000419673.2
ENST00000531294.1
Rho GTPase activating protein 28
chr11_+_49050504 0.21 ENST00000332682.7
tripartite motif containing 49B
chr8_-_27115903 0.21 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr11_+_55029628 0.20 ENST00000417545.2
tripartite motif containing 48
chr22_-_46450024 0.20 ENST00000396008.2
ENST00000333761.1
chromosome 22 open reading frame 26
chr17_+_7328925 0.20 ENST00000333870.3
ENST00000574034.1
chromosome 17 open reading frame 74
chr11_-_71639480 0.20 ENST00000529513.1
Putative short transient receptor potential channel 2-like protein
chr17_-_29624343 0.19 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr12_+_10460417 0.19 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
killer cell lectin-like receptor subfamily D, member 1
chr14_-_106518922 0.19 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr13_+_78315466 0.18 ENST00000314070.5
ENST00000462234.1
SLAIN motif family, member 1
chr10_-_32667660 0.18 ENST00000375110.2
enhancer of polycomb homolog 1 (Drosophila)
chr16_+_29991673 0.17 ENST00000416441.2
TAO kinase 2
chr14_+_56127989 0.17 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr5_+_138609782 0.17 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
matrin 3
chr12_-_9885888 0.16 ENST00000327839.3
C-type lectin-like 1
chr14_-_45252031 0.16 ENST00000556405.1
RP11-398E10.1
chr12_-_54652060 0.16 ENST00000552562.1
chromobox homolog 5
chr6_-_42690312 0.16 ENST00000230381.5
peripherin 2 (retinal degeneration, slow)
chr3_+_126113734 0.16 ENST00000352312.1
ENST00000393425.1
coiled-coil domain containing 37
chr17_-_39306054 0.16 ENST00000343246.4
keratin associated protein 4-5
chr13_+_24553933 0.15 ENST00000424834.2
ENST00000439928.2
spermatogenesis associated 13
RP11-309I15.1
chrX_+_22056165 0.15 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr7_+_54610124 0.14 ENST00000402026.2
V-set and transmembrane domain containing 2A
chr13_-_38443860 0.14 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
transient receptor potential cation channel, subfamily C, member 4
chr3_+_98699880 0.14 ENST00000473756.1
long intergenic non-protein coding RNA 973

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.8 3.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.7 3.9 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 1.6 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.4 1.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 0.9 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3 3.9 GO:0046541 saliva secretion(GO:0046541)
0.2 0.9 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 0.6 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 0.8 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 1.5 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.5 GO:0045925 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.2 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 1.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 16.4 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.4 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.7 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.3 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.4 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 1.7 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 3.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 0.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 0.3 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 0.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.4 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.4 GO:0040031 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.0 0.8 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.9 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 1.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 1.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:1903276 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.9 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 4.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.3 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 1.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 4.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.7 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 3.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.6 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0046848 hydroxyapatite binding(GO:0046848)
0.5 2.6 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.5 3.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.5 2.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 1.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 17.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 0.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.0 GO:0070728 leucine binding(GO:0070728)
0.1 0.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.6 GO:0031013 troponin I binding(GO:0031013)
0.1 3.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 6.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.6 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.9 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 4.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0019237 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.4 PID INSULIN PATHWAY Insulin Pathway
0.0 2.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 17.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 4.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism