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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFAP2B

Z-value: 0.84

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
TFAP2B
ENSG00000008196.8 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v2_chr6_+_50786414_507864390.173.6e-01Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_148521381 2.72 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr5_+_148521046 2.52 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chr5_+_148521136 2.49 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr5_-_157002775 2.17 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr19_+_35645817 2.00 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_35645618 1.95 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_89746173 1.90 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr18_-_21242774 1.88 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr21_-_28217721 1.85 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_17575584 1.85 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr21_-_45078019 1.81 ENST00000542962.1
HSF2BP
heat shock transcription factor 2 binding protein
chr20_+_62327996 1.70 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr1_+_152881014 1.66 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr1_+_155178518 1.57 ENST00000316721.4
MTX1
metaxin 1
chr18_-_21242833 1.50 ENST00000586087.1
ENST00000592179.1
ANKRD29
ankyrin repeat domain 29
chr12_-_57634475 1.43 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_155178481 1.38 ENST00000368376.3
MTX1
metaxin 1
chr1_-_20812690 1.37 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr5_-_157002749 1.37 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr6_-_30654977 1.36 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr3_-_196756646 1.29 ENST00000439320.1
ENST00000296351.4
ENST00000296350.5
MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr14_+_65171315 1.26 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_32042105 1.26 ENST00000457433.2
ENST00000441210.2
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_32042131 1.25 ENST00000271064.7
ENST00000537531.1
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_-_9189229 1.23 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr4_+_1723197 1.23 ENST00000485989.2
ENST00000313288.4
TACC3
transforming, acidic coiled-coil containing protein 3
chr1_-_75198940 1.15 ENST00000417775.1
CRYZ
crystallin, zeta (quinone reductase)
chr19_-_11689752 1.14 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr14_+_94640633 1.14 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr1_-_75198681 1.14 ENST00000370872.3
ENST00000370871.3
ENST00000340866.5
ENST00000370870.1
CRYZ
crystallin, zeta (quinone reductase)
chr1_+_155179012 1.12 ENST00000609421.1
MTX1
metaxin 1
chr9_-_123639304 1.12 ENST00000436309.1
PHF19
PHD finger protein 19
chr14_+_65171099 1.11 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_+_131182697 1.07 ENST00000372838.4
ENST00000411852.1
CERCAM
cerebral endothelial cell adhesion molecule
chr1_+_107683644 0.96 ENST00000370067.1
NTNG1
netrin G1
chr18_+_33877654 0.95 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr1_+_182992545 0.94 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr11_-_7694684 0.92 ENST00000524790.1
ENST00000299497.9
ENST00000299498.6
CYB5R2
cytochrome b5 reductase 2
chr20_+_60174827 0.90 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr1_+_107683436 0.89 ENST00000370068.1
NTNG1
netrin G1
chr8_-_144655141 0.88 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr11_-_7695437 0.88 ENST00000533558.1
ENST00000527542.1
ENST00000531096.1
CYB5R2
cytochrome b5 reductase 2
chr3_-_52090461 0.87 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr2_-_43453734 0.86 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr15_-_74501360 0.86 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr2_-_208030647 0.83 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_+_154377669 0.82 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr20_-_56285595 0.81 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr12_-_48152853 0.80 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr12_-_48152611 0.77 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr16_+_30960375 0.77 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr16_+_2867228 0.77 ENST00000005995.3
ENST00000574813.1
PRSS21
protease, serine, 21 (testisin)
chr20_-_49639631 0.76 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr9_-_123639600 0.75 ENST00000373896.3
PHF19
PHD finger protein 19
chr16_+_2867164 0.75 ENST00000455114.1
ENST00000450020.3
PRSS21
protease, serine, 21 (testisin)
chr12_+_110011571 0.73 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr15_+_41624892 0.72 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
NUSAP1
nucleolar and spindle associated protein 1
chr1_+_179561011 0.72 ENST00000294848.8
ENST00000444136.1
TDRD5
tudor domain containing 5
chr16_+_81478775 0.72 ENST00000537098.3
CMIP
c-Maf inducing protein
chr17_+_80332153 0.72 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr11_+_43964055 0.71 ENST00000528572.1
C11orf96
chromosome 11 open reading frame 96
chr22_+_21987005 0.71 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
CCDC116
coiled-coil domain containing 116
chr10_-_75401500 0.70 ENST00000359322.4
MYOZ1
myozenin 1
chr9_+_78505554 0.70 ENST00000545128.1
PCSK5
proprotein convertase subtilisin/kexin type 5
chr7_-_100065686 0.70 ENST00000423266.1
ENST00000456330.1
TSC22D4
TSC22 domain family, member 4
chr2_-_220408430 0.70 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr22_+_42665742 0.69 ENST00000332965.3
ENST00000415205.1
ENST00000446578.1
Z83851.3
Z83851.3
chr14_+_74815116 0.69 ENST00000256362.4
VRTN
vertebrae development associated
chrX_-_15872914 0.68 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_26232951 0.68 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr16_+_1583567 0.67 ENST00000566264.1
TMEM204
transmembrane protein 204
chr12_+_56414851 0.66 ENST00000547167.1
IKZF4
IKAROS family zinc finger 4 (Eos)
chr8_-_145018905 0.66 ENST00000398774.2
PLEC
plectin
chr19_-_55660561 0.66 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr2_+_120770645 0.62 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr19_+_17858547 0.61 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCHO1
FCH domain only 1
chr16_+_22825475 0.61 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr14_+_94393605 0.61 ENST00000556222.1
ENST00000554404.1
ENST00000557000.2
FAM181A
family with sequence similarity 181, member A
chr19_+_17858509 0.58 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr13_+_52158610 0.57 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr12_-_48152428 0.57 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr6_+_151186554 0.57 ENST00000367321.3
ENST00000367307.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr10_-_99393242 0.56 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN4
MORN repeat containing 4
chr10_+_135340859 0.56 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr20_-_50808236 0.55 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein
chr17_-_8093471 0.55 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr17_-_41856305 0.55 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr22_-_36424458 0.55 ENST00000438146.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_+_111169565 0.54 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chr2_+_202899310 0.54 ENST00000286201.1
FZD7
frizzled family receptor 7
chr14_+_92980111 0.53 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr19_+_46144884 0.53 ENST00000593161.1
AC006132.1
chromosome 19 open reading frame 83
chr1_+_55013889 0.52 ENST00000343744.2
ENST00000371316.3
ACOT11
acyl-CoA thioesterase 11
chr19_+_45971246 0.52 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr14_+_94640671 0.52 ENST00000328839.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr14_+_24540046 0.52 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr5_+_60933634 0.51 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr19_-_38397228 0.51 ENST00000447313.2
WDR87
WD repeat domain 87
chr10_+_71078595 0.51 ENST00000359426.6
HK1
hexokinase 1
chr12_-_30907862 0.50 ENST00000541765.1
ENST00000537108.1
CAPRIN2
caprin family member 2
chr15_-_79383102 0.49 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr22_-_20255212 0.49 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr19_+_50706866 0.49 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr6_+_54711533 0.49 ENST00000306858.7
FAM83B
family with sequence similarity 83, member B
chr7_-_143105941 0.48 ENST00000275815.3
EPHA1
EPH receptor A1
chrX_+_131157609 0.48 ENST00000496850.1
MST4
Serine/threonine-protein kinase MST4
chr1_+_40506392 0.48 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr16_+_3194211 0.48 ENST00000428155.1
CASP16
caspase 16, apoptosis-related cysteine peptidase (putative)
chr19_+_11546153 0.47 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr16_+_6533380 0.47 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr22_-_33454354 0.47 ENST00000358763.2
SYN3
synapsin III
chr5_-_174871136 0.47 ENST00000393752.2
DRD1
dopamine receptor D1
chrX_-_78622805 0.46 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr22_-_25801333 0.46 ENST00000444995.3
LRP5L
low density lipoprotein receptor-related protein 5-like
chr19_-_41859814 0.46 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr10_+_124221036 0.46 ENST00000368984.3
HTRA1
HtrA serine peptidase 1
chr1_+_2398876 0.46 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr3_-_128206759 0.46 ENST00000430265.2
GATA2
GATA binding protein 2
chr19_+_11546093 0.46 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr19_+_42301079 0.46 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr16_+_81678957 0.45 ENST00000398040.4
CMIP
c-Maf inducing protein
chr1_+_11994715 0.45 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr9_+_90112741 0.45 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr12_-_53189892 0.44 ENST00000309505.3
ENST00000417996.2
KRT3
keratin 3
chr5_+_177540444 0.44 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr18_-_34408802 0.44 ENST00000590842.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr13_-_25745857 0.43 ENST00000381853.3
AMER2
APC membrane recruitment protein 2
chr10_-_99393208 0.43 ENST00000307450.6
MORN4
MORN repeat containing 4
chr9_+_5629025 0.42 ENST00000251879.6
ENST00000414202.2
KIAA1432
KIAA1432
chr1_-_31902614 0.42 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chrX_+_49028265 0.42 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr14_+_79745682 0.42 ENST00000557594.1
NRXN3
neurexin 3
chr11_-_64512469 0.42 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_-_220174166 0.42 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chrX_-_154033793 0.42 ENST00000369534.3
ENST00000413259.3
MPP1
membrane protein, palmitoylated 1, 55kDa
chr13_-_20437648 0.42 ENST00000382907.4
ENST00000382905.4
ZMYM5
zinc finger, MYM-type 5
chr1_-_180471947 0.41 ENST00000367595.3
ACBD6
acyl-CoA binding domain containing 6
chr11_+_60995849 0.41 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr8_-_145047688 0.41 ENST00000356346.3
PLEC
plectin
chr1_+_236849754 0.41 ENST00000542672.1
ENST00000366578.4
ACTN2
actinin, alpha 2
chr12_+_53693466 0.40 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr11_-_61062762 0.40 ENST00000335613.5
VWCE
von Willebrand factor C and EGF domains
chr14_+_79745746 0.40 ENST00000281127.7
NRXN3
neurexin 3
chr14_-_91720224 0.39 ENST00000238699.3
ENST00000531499.2
GPR68
G protein-coupled receptor 68
chr19_+_37742773 0.39 ENST00000438770.2
ENST00000591116.1
ENST00000592712.1
AC012309.5
AC012309.5
chr14_+_79746249 0.39 ENST00000428277.2
NRXN3
neurexin 3
chr6_+_152128810 0.38 ENST00000406599.1
ESR1
estrogen receptor 1
chr17_-_5487768 0.38 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1
NLR family, pyrin domain containing 1
chr19_+_13229126 0.38 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr11_+_69455855 0.38 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr1_+_172628154 0.38 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr11_-_64512273 0.37 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_14586125 0.37 ENST00000292513.3
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr17_-_61777459 0.37 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr9_+_78505581 0.37 ENST00000376767.3
ENST00000376752.4
PCSK5
proprotein convertase subtilisin/kexin type 5
chr22_-_29075853 0.37 ENST00000397906.2
TTC28
tetratricopeptide repeat domain 28
chr9_+_112542591 0.36 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr9_-_34523027 0.36 ENST00000399775.2
ENHO
energy homeostasis associated
chr11_-_535515 0.36 ENST00000311189.7
ENST00000451590.1
ENST00000417302.1
HRAS
Harvey rat sarcoma viral oncogene homolog
chr7_+_127292234 0.35 ENST00000354725.3
SND1
staphylococcal nuclease and tudor domain containing 1
chr1_+_155006300 0.35 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr2_+_120770581 0.35 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr16_+_68679193 0.35 ENST00000581171.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_+_10828795 0.35 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
DNM2
dynamin 2
chr1_+_64059332 0.35 ENST00000540265.1
PGM1
phosphoglucomutase 1
chr4_-_41216492 0.35 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr2_+_130939827 0.34 ENST00000409255.1
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr22_+_46692638 0.34 ENST00000454366.1
GTSE1
G-2 and S-phase expressed 1
chr7_-_27142290 0.34 ENST00000222718.5
HOXA2
homeobox A2
chr19_+_10828724 0.33 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr19_+_1067144 0.33 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr5_-_1445539 0.33 ENST00000270349.9
SLC6A3
solute carrier family 6 (neurotransmitter transporter), member 3
chr19_-_16738984 0.33 ENST00000600060.1
ENST00000263390.3
MED26
mediator complex subunit 26
chr19_+_39616410 0.33 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr4_-_41216619 0.33 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr19_+_572543 0.33 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
BSG
basigin (Ok blood group)
chr21_-_47575481 0.32 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD
formimidoyltransferase cyclodeaminase
chr19_+_1067492 0.32 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr19_+_55897297 0.32 ENST00000431533.2
ENST00000428193.2
ENST00000558815.1
ENST00000560583.1
ENST00000560055.1
ENST00000559463.1
RPL28
ribosomal protein L28
chr1_+_113051400 0.32 ENST00000369684.4
WNT2B
wingless-type MMTV integration site family, member 2B
chr19_-_12945362 0.32 ENST00000590404.1
ENST00000592204.1
RTBDN
retbindin
chr11_+_64002292 0.32 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr12_-_32908809 0.32 ENST00000324868.8
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial
chr11_+_64001962 0.32 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr8_-_70983506 0.32 ENST00000276594.2
PRDM14
PR domain containing 14
chr14_-_94254821 0.32 ENST00000393140.1
PRIMA1
proline rich membrane anchor 1
chr19_+_7459998 0.32 ENST00000319670.9
ENST00000599752.1
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr20_-_55100981 0.32 ENST00000243913.4
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr4_-_41216473 0.32 ENST00000513140.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr16_+_68678892 0.31 ENST00000429102.2
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr13_+_28712614 0.31 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_135476552 0.31 ENST00000281924.6
TMEM163
transmembrane protein 163
chr7_-_27213893 0.31 ENST00000283921.4
HOXA10
homeobox A10
chr1_+_40505891 0.31 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr9_+_134165063 0.31 ENST00000372264.3
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr12_-_53171128 0.31 ENST00000332411.2
KRT76
keratin 76
chr12_+_31477250 0.31 ENST00000313737.4
AC024940.1
AC024940.1
chr5_+_149980622 0.31 ENST00000394243.1
SYNPO
synaptopodin
chr15_+_78730622 0.30 ENST00000560440.1
IREB2
iron-responsive element binding protein 2
chr5_-_134369973 0.30 ENST00000265340.7
PITX1
paired-like homeodomain 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.6 1.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.6 1.7 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 2.1 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.4 1.8 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 0.8 GO:0002384 hepatic immune response(GO:0002384)
0.2 1.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.7 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 1.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.7 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.2 0.7 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.2 1.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.2 1.0 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.6 GO:0007398 ectoderm development(GO:0007398)
0.2 0.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 1.9 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 0.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.2 0.5 GO:1900126 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 0.5 GO:0097187 dentinogenesis(GO:0097187)
0.2 0.5 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.6 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.6 GO:0010193 response to ozone(GO:0010193)
0.1 2.6 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 1.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.3 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.5 GO:0035106 operant conditioning(GO:0035106)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.3 GO:0050894 determination of affect(GO:0050894)
0.1 0.5 GO:0001712 ectodermal cell fate commitment(GO:0001712) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 1.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.2 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.6 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 3.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 7.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.3 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.1 0.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.4 GO:2000630 response to isolation stress(GO:0035900) positive regulation of miRNA metabolic process(GO:2000630)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.6 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 1.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.2 GO:0003335 corneocyte development(GO:0003335)
0.1 0.5 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.3 GO:2001181 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.6 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0032196 transposition(GO:0032196)
0.0 0.7 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.5 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.4 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.3 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 3.6 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.0 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.9 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.7 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0071839 apoptotic process in bone marrow(GO:0071839)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 1.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.5 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.4 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.5 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.3 GO:0042416 dopamine biosynthetic process(GO:0042416) dopamine catabolic process(GO:0042420)
0.0 0.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 3.4 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.5 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.7 GO:0071622 regulation of granulocyte chemotaxis(GO:0071622)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839) venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.3 GO:0048535 lymph node development(GO:0048535)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0007127 meiosis I(GO:0007127)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0 0.0 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 0.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0097444 spine apparatus(GO:0097444)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 0.7 GO:0071546 pi-body(GO:0071546)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 7.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.2 GO:0031143 pseudopodium(GO:0031143)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 2.1 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 2.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.5 2.3 GO:0070404 NADH binding(GO:0070404)
0.4 1.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 0.8 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 1.1 GO:0051373 FATZ binding(GO:0051373)
0.2 3.3 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.2 2.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 0.7 GO:0004803 transposase activity(GO:0004803)
0.2 0.5 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 2.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.5 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.3 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.3 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 1.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.6 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.5 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 3.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0031014 troponin T binding(GO:0031014)
0.0 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0015039 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0 1.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 5.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.0 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 3.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 7.1 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 2.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 7.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 3.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 4.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.3 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation