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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFAP4_MSC

Z-value: 0.71

Motif logo

Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
ENSG00000090447.7 transcription factor AP-4
ENSG00000178860.8 musculin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSChg19_v2_chr8_-_72756667_72756736-0.328.9e-02Click!
TFAP4hg19_v2_chr16_-_4323015_43230760.163.9e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_24911195 6.31 ENST00000259698.4
family with sequence similarity 65, member B
chr16_-_21289627 4.73 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr3_+_3841108 4.41 ENST00000319331.3
leucine rich repeat neuronal 1
chr16_-_67427389 4.16 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr6_-_39197226 2.85 ENST00000359534.3
potassium channel, subfamily K, member 5
chr8_-_72274095 2.80 ENST00000303824.7
eyes absent homolog 1 (Drosophila)
chr20_-_39317868 2.77 ENST00000373313.2
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr15_-_40401062 2.51 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
Bcl2 modifying factor
chr11_+_45918092 2.38 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr2_+_85981008 2.27 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr6_+_17281573 2.24 ENST00000379052.5
RNA binding motif protein 24
chr8_-_110660999 2.13 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
syntabulin (syntaxin-interacting)
chr4_+_75858318 1.89 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr22_-_36013368 1.80 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr12_+_49297899 1.77 ENST00000552942.1
ENST00000320516.4
coiled-coil domain containing 65
chr9_-_112970436 1.70 ENST00000400613.4
chromosome 9 open reading frame 152
chr8_+_81398444 1.67 ENST00000455036.3
ENST00000426744.2
zinc finger and BTB domain containing 10
chr1_-_216896780 1.61 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
estrogen-related receptor gamma
chr4_+_75858290 1.59 ENST00000513238.1
prostate androgen-regulated mucin-like protein 1
chr5_+_50678921 1.55 ENST00000230658.7
ISL LIM homeobox 1
chr1_+_212738676 1.54 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr8_-_72274467 1.49 ENST00000340726.3
eyes absent homolog 1 (Drosophila)
chr17_+_4981535 1.49 ENST00000318833.3
ZFP3 zinc finger protein
chr10_-_102089729 1.48 ENST00000465680.2
polycystic kidney disease 2-like 1
chr10_+_94594351 1.43 ENST00000371552.4
exocyst complex component 6
chr8_+_81397876 1.41 ENST00000430430.1
zinc finger and BTB domain containing 10
chr12_+_104458235 1.40 ENST00000229330.4
host cell factor C2
chr22_+_31003133 1.39 ENST00000405742.3
transcobalamin II
chr1_-_183622442 1.36 ENST00000308641.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr22_+_31002779 1.36 ENST00000215838.3
transcobalamin II
chr2_+_233562015 1.33 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr1_-_150669500 1.28 ENST00000271732.3
golgi phosphoprotein 3-like
chr21_-_34185944 1.27 ENST00000479548.1
chromosome 21 open reading frame 62
chr17_+_68071389 1.25 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_68071458 1.24 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr15_+_67547163 1.23 ENST00000335894.4
IQ motif containing H
chr4_+_74702214 1.21 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr11_-_85430204 1.19 ENST00000389958.3
ENST00000527794.1
synaptotagmin-like 2
chr3_-_183273477 1.16 ENST00000341319.3
kelch-like family member 6
chr11_-_85430163 1.15 ENST00000529581.1
ENST00000533577.1
synaptotagmin-like 2
chr1_+_14075865 1.11 ENST00000413440.1
PR domain containing 2, with ZNF domain
chr11_+_73675873 1.08 ENST00000537753.1
ENST00000542350.1
DnaJ (Hsp40) homolog, subfamily B, member 13
chr16_+_83932684 1.07 ENST00000262430.4
malonyl-CoA decarboxylase
chr7_-_120497178 1.01 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr3_+_49057876 1.00 ENST00000326912.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr12_+_56473628 0.94 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr3_+_49058444 0.93 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_-_39339777 0.93 ENST00000397572.2
MYC binding protein
chr12_+_49297887 0.92 ENST00000266984.5
coiled-coil domain containing 65
chr11_+_7597639 0.91 ENST00000533792.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr22_+_35776828 0.91 ENST00000216117.8
heme oxygenase (decycling) 1
chr7_-_30029574 0.90 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
secernin 1
chr22_+_31003190 0.86 ENST00000407817.3
transcobalamin II
chr4_+_86699834 0.85 ENST00000395183.2
Rho GTPase activating protein 24
chr2_-_73460334 0.84 ENST00000258083.2
protease-associated domain containing 1
chr7_+_128784712 0.84 ENST00000289407.4
tetraspanin 33
chr7_-_30029367 0.82 ENST00000242059.5
secernin 1
chr1_+_15272271 0.82 ENST00000400797.3
kazrin, periplakin interacting protein
chr15_+_43809797 0.82 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr1_+_110082487 0.81 ENST00000527748.1
G protein-coupled receptor 61
chr19_+_18208603 0.80 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr13_-_41635512 0.79 ENST00000405737.2
E74-like factor 1 (ets domain transcription factor)
chr3_-_120365866 0.79 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr2_+_97203082 0.79 ENST00000454558.2
AT rich interactive domain 5A (MRF1-like)
chr16_-_31076332 0.78 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
zinc finger protein 668
chr1_+_14075903 0.76 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PR domain containing 2, with ZNF domain
chr2_-_27603582 0.76 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr14_-_53019211 0.76 ENST00000557374.1
ENST00000281741.4
thioredoxin domain containing 16
chr5_+_102201687 0.76 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr1_-_24741525 0.76 ENST00000374409.1
sperm-tail PG-rich repeat containing 1
chr6_-_76203454 0.74 ENST00000237172.7
filamin A interacting protein 1
chr3_-_65583561 0.74 ENST00000460329.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_167063282 0.73 ENST00000361200.2
dual specificity phosphatase 27 (putative)
chr6_-_76203345 0.73 ENST00000393004.2
filamin A interacting protein 1
chr2_+_230787201 0.73 ENST00000283946.3
F-box protein 36
chr7_-_99869799 0.73 ENST00000436886.2
GATS, stromal antigen 3 opposite strand
chr12_+_109826524 0.72 ENST00000431443.2
myosin IH
chr7_+_116660246 0.72 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
suppression of tumorigenicity 7
chr11_-_62474803 0.72 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_+_102201509 0.71 ENST00000348126.2
ENST00000379787.4
peptidylglycine alpha-amidating monooxygenase
chr10_+_95848824 0.71 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chrX_-_10851762 0.70 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr3_-_52486841 0.70 ENST00000496590.1
troponin C type 1 (slow)
chr20_+_44098346 0.69 ENST00000372676.3
WAP four-disulfide core domain 2
chr12_+_72233487 0.69 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1 domain family, member 15
chr6_-_31697255 0.69 ENST00000436437.1
dimethylarginine dimethylaminohydrolase 2
chr6_+_46761118 0.68 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr5_+_102201722 0.67 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chr2_-_158345462 0.66 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr12_+_122150646 0.66 ENST00000449592.2
transmembrane protein 120B
chr3_-_64211112 0.64 ENST00000295902.6
prickle homolog 2 (Drosophila)
chr6_+_44184653 0.63 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
chr6_+_90272027 0.63 ENST00000522441.1
ankyrin repeat domain 6
chr19_+_10527449 0.62 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr14_-_23288930 0.62 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_58755184 0.62 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr12_-_54121261 0.61 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr11_+_71498552 0.61 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
family with sequence similarity 86, member C1
chr3_-_193272741 0.61 ENST00000392443.3
ATPase type 13A4
chr3_-_193272874 0.59 ENST00000342695.4
ATPase type 13A4
chr11_+_1944054 0.59 ENST00000397301.1
ENST00000397304.2
ENST00000446240.1
troponin T type 3 (skeletal, fast)
chr1_-_86043921 0.59 ENST00000535924.2
dimethylarginine dimethylaminohydrolase 1
chr12_-_54121212 0.58 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
calcium binding and coiled-coil domain 1
chr12_+_86268065 0.58 ENST00000551529.1
ENST00000256010.6
neurotensin
chr2_+_95537170 0.57 ENST00000295201.4
tektin 4
chr20_+_53092123 0.56 ENST00000262593.5
docking protein 5
chr22_+_39052632 0.55 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
chibby homolog 1 (Drosophila)
chr1_-_175712665 0.55 ENST00000263525.2
tenascin R
chr8_-_95961578 0.55 ENST00000448464.2
ENST00000342697.4
tumor protein p53 inducible nuclear protein 1
chr16_-_31076273 0.54 ENST00000426488.2
zinc finger protein 668
chr20_+_33292068 0.54 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
tumor protein p53 inducible nuclear protein 2
chr14_+_45431379 0.54 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
family with sequence similarity 179, member B
chrX_-_108868390 0.54 ENST00000372101.2
KCNE1-like
chr8_+_98788003 0.54 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr1_+_174844645 0.53 ENST00000486220.1
RAB GTPase activating protein 1-like
chr16_-_4323015 0.53 ENST00000204517.6
transcription factor AP-4 (activating enhancer binding protein 4)
chr2_-_148779106 0.52 ENST00000416719.1
ENST00000264169.2
origin recognition complex, subunit 4
chr8_+_98788057 0.52 ENST00000517924.1
lysosomal protein transmembrane 4 beta
chr3_-_52868931 0.52 ENST00000486659.1
musculoskeletal, embryonic nuclear protein 1
chr15_-_75748115 0.51 ENST00000360439.4
SIN3 transcription regulator family member A
chr20_-_40247133 0.51 ENST00000373233.3
ENST00000309279.7
chromodomain helicase DNA binding protein 6
chr12_-_50297638 0.51 ENST00000320634.3
Fas apoptotic inhibitory molecule 2
chr20_+_53092232 0.50 ENST00000395939.1
docking protein 5
chr17_+_26800648 0.50 ENST00000545060.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr4_-_103682145 0.50 ENST00000226578.4
mannosidase, beta A, lysosomal
chr17_+_26800756 0.49 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr20_+_43160409 0.49 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr9_-_123239632 0.49 ENST00000416449.1
CDK5 regulatory subunit associated protein 2
chr2_-_154335300 0.49 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr8_-_71581377 0.49 ENST00000276590.4
ENST00000522447.1
lactamase, beta 2
chr1_+_223101757 0.48 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr11_+_6411670 0.48 ENST00000530395.1
ENST00000527275.1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr14_+_24584508 0.47 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DDB1 and CUL4 associated factor 11
chr5_+_102201430 0.47 ENST00000438793.3
ENST00000346918.2
peptidylglycine alpha-amidating monooxygenase
chr1_+_172422026 0.47 ENST00000367725.4
chromosome 1 open reading frame 105
chr15_-_52944231 0.47 ENST00000546305.2
family with sequence similarity 214, member A
chr17_+_1627834 0.46 ENST00000419248.1
ENST00000418841.1
WD repeat domain 81
chr5_+_49962772 0.46 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr6_-_31651817 0.46 ENST00000375863.3
ENST00000375860.2
lymphocyte antigen 6 complex, locus G5C
chr18_-_19180681 0.45 ENST00000269214.5
establishment of sister chromatid cohesion N-acetyltransferase 1
chr17_+_7462103 0.45 ENST00000396545.4
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_52869205 0.45 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr20_+_44098385 0.45 ENST00000217425.5
ENST00000339946.3
WAP four-disulfide core domain 2
chr7_-_92855762 0.44 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr9_-_13165457 0.44 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
multiple PDZ domain protein
chr6_-_39399087 0.44 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
kinesin family member 6
chr12_-_50298000 0.43 ENST00000550635.2
Fas apoptotic inhibitory molecule 2
chr16_-_5147743 0.43 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
family with sequence similarity 86, member A
chr17_+_26800296 0.43 ENST00000444914.3
ENST00000314669.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr5_+_43603229 0.43 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr17_+_7462031 0.43 ENST00000380535.4
tumor necrosis factor (ligand) superfamily, member 13
chr17_-_47755436 0.42 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
speckle-type POZ protein
chr2_+_231280954 0.42 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100 nuclear antigen
chr3_-_49058479 0.42 ENST00000440857.1
DALR anticodon binding domain containing 3
chr1_+_159750720 0.42 ENST00000368109.1
ENST00000368108.3
dual specificity phosphatase 23
chr2_+_68384976 0.42 ENST00000263657.2
partner of NOB1 homolog (S. cerevisiae)
chr1_+_159750776 0.42 ENST00000368107.1
dual specificity phosphatase 23
chr11_+_6411636 0.41 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
sphingomyelin phosphodiesterase 1, acid lysosomal
chrY_+_14774265 0.41 ENST00000457658.1
ENST00000440408.1
ENST00000543097.1
testis-specific transcript, Y-linked 15 (non-protein coding)
chr15_+_67547113 0.40 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQ motif containing H
chr12_+_122667658 0.40 ENST00000339777.4
ENST00000425921.1
leucine rich repeat containing 43
chr17_-_7145106 0.40 ENST00000577035.1
GABA(A) receptor-associated protein
chr5_+_145583156 0.40 ENST00000265271.5
RNA binding motif protein 27
chr9_+_2717502 0.40 ENST00000382082.3
potassium channel, subfamily V, member 2
chr11_+_71938925 0.40 ENST00000538751.1
inositol polyphosphate phosphatase-like 1
chr17_-_26989136 0.40 ENST00000247020.4
stromal cell-derived factor 2
chr10_-_62149433 0.39 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr19_-_46285646 0.39 ENST00000458663.2
dystrophia myotonica-protein kinase
chr9_+_2159850 0.39 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_-_85430088 0.39 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr20_+_62697564 0.39 ENST00000458442.1
transcription elongation factor A (SII), 2
chr5_-_58571935 0.38 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr2_+_137523086 0.38 ENST00000409968.1
thrombospondin, type I, domain containing 7B
chr12_-_56122426 0.38 ENST00000551173.1
CD63 molecule
chr6_-_31697563 0.38 ENST00000375789.2
ENST00000416410.1
dimethylarginine dimethylaminohydrolase 2
chr16_+_71929397 0.38 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
increased sodium tolerance 1 homolog (yeast)
chr15_-_42749711 0.37 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr2_+_97202480 0.37 ENST00000357485.3
AT rich interactive domain 5A (MRF1-like)
chr15_-_83680325 0.37 ENST00000508990.2
ENST00000510873.2
ENST00000538348.2
ENST00000451195.3
ENST00000513601.2
ENST00000304177.5
ENST00000565712.1
chromosome 15 open reading frame 40
chr16_-_84273304 0.37 ENST00000308251.4
ENST00000568181.1
potassium voltage-gated channel, subfamily G, member 4
chr2_-_148778323 0.36 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr19_+_1041212 0.36 ENST00000433129.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr19_+_7587491 0.36 ENST00000264079.6
mucolipin 1
chr1_-_33647267 0.36 ENST00000291416.5
tripartite motif containing 62
chr8_-_38008783 0.35 ENST00000276449.4
steroidogenic acute regulatory protein
chr10_+_88428206 0.35 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chr17_-_38083843 0.35 ENST00000304046.2
ENST00000579695.1
ORM1-like 3 (S. cerevisiae)
chr4_+_159727272 0.35 ENST00000379346.3
folliculin interacting protein 2
chr4_+_154178520 0.35 ENST00000433687.1
tripartite motif containing 2
chr3_+_32147997 0.34 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr10_+_102790980 0.34 ENST00000393459.1
ENST00000224807.5
sideroflexin 3
chr4_-_140223670 0.34 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr8_-_74791051 0.34 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
ubiquitin-conjugating enzyme E2W (putative)
chr6_+_30852130 0.33 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
discoidin domain receptor tyrosine kinase 1
chr2_+_179149636 0.33 ENST00000409631.1
oxysterol binding protein-like 6
chr6_+_30851840 0.32 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
discoidin domain receptor tyrosine kinase 1
chr17_+_73521763 0.32 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
lethal giant larvae homolog 2 (Drosophila)
chr17_-_80275466 0.31 ENST00000312648.3
CD7 molecule
chr1_-_68915610 0.31 ENST00000262340.5
retinal pigment epithelium-specific protein 65kDa
chr21_-_34185989 0.31 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.7 2.6 GO:0018032 protein amidation(GO:0018032)
0.5 1.6 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.5 1.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 4.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 3.5 GO:0015889 cobalamin transport(GO:0015889)
0.3 4.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 0.9 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.3 2.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 1.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 1.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 1.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.2 2.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 0.5 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.7 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.7 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 2.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.9 GO:0023021 termination of signal transduction(GO:0023021)
0.1 1.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.4 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 1.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.4 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.4 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 2.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.8 GO:0051604 protein maturation(GO:0051604)
0.1 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 1.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 2.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0001893 maternal placenta development(GO:0001893)
0.1 0.2 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.1 0.4 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.9 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.1 1.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.2 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 3.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 0.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.2 GO:0002467 germinal center formation(GO:0002467)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.4 GO:0032868 response to insulin(GO:0032868)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 4.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 4.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.5 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0001554 luteolysis(GO:0001554)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 2.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 2.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 1.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0098727 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0 0.2 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 1.6 GO:0006397 mRNA processing(GO:0006397)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0070997 neuron death(GO:0070997)
0.0 0.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.0 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.2 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.4 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.0 GO:0002265 astrocyte activation involved in immune response(GO:0002265)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.4 4.2 GO:0097427 microtubule bundle(GO:0097427)
0.3 2.4 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.7 GO:0072534 perineuronal net(GO:0072534)
0.2 1.3 GO:1990635 proximal dendrite(GO:1990635)
0.2 2.1 GO:0097433 dense body(GO:0097433)
0.1 0.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 6.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.4 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.9 GO:0042599 lamellar body(GO:0042599)
0.0 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 4.6 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 3.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 2.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 3.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.6 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.8 GO:0043235 receptor complex(GO:0043235)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701) junctional membrane complex(GO:0030314)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 2.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.4 GO:0005770 late endosome(GO:0005770)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.7 2.6 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5 1.4 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.3 3.6 GO:0031419 cobalamin binding(GO:0031419)
0.3 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 1.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 2.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.4 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 2.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0090541 MIT domain binding(GO:0090541)
0.1 2.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 1.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.5 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 1.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 2.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0015923 mannose binding(GO:0005537) mannosidase activity(GO:0015923)
0.0 5.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 1.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 5.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.0 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism