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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFCP2

Z-value: 0.81

Motif logo

Transcription factors associated with TFCP2

Gene Symbol Gene ID Gene Info
ENSG00000135457.5 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2hg19_v2_chr12_-_51566849_51566927-0.291.2e-01Click!

Activity profile of TFCP2 motif

Sorted Z-values of TFCP2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_113542063 2.75 ENST00000263339.3
interleukin 1, alpha
chr5_-_149669192 2.43 ENST00000398376.3
calcium/calmodulin-dependent protein kinase II alpha
chr4_-_80994619 2.34 ENST00000404191.1
anthrax toxin receptor 2
chr14_+_75746781 1.96 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr5_-_39219705 1.72 ENST00000351578.6
FYN binding protein
chr20_-_5591626 1.57 ENST00000379019.4
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr5_-_39219641 1.52 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chr11_+_62649158 1.42 ENST00000539891.1
ENST00000536981.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_+_45212074 1.36 ENST00000372217.1
kinesin family member 2C
chr10_-_90611566 1.24 ENST00000371930.4
ankyrin repeat domain 22
chr10_+_88718314 1.23 ENST00000348795.4
synuclein, gamma (breast cancer-specific protein 1)
chr1_+_45212051 1.19 ENST00000372222.3
kinesin family member 2C
chr12_+_41086297 1.16 ENST00000551295.2
contactin 1
chr22_+_25003626 1.14 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
gamma-glutamyltransferase 1
chr6_+_31371337 1.05 ENST00000449934.2
ENST00000421350.1
MHC class I polypeptide-related sequence A
chr18_-_67873078 1.01 ENST00000255674.6
rotatin
chr5_+_137514687 0.99 ENST00000394894.3
kinesin family member 20A
chr4_-_174255400 0.99 ENST00000506267.1
high mobility group box 2
chr10_-_33625154 0.98 ENST00000265371.4
neuropilin 1
chr5_+_137514834 0.95 ENST00000508792.1
ENST00000504621.1
kinesin family member 20A
chr12_+_93963590 0.95 ENST00000340600.2
suppressor of cytokine signaling 2
chrX_+_64887512 0.92 ENST00000360270.5
moesin
chr17_+_26662597 0.92 ENST00000544907.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr20_-_46415341 0.91 ENST00000484875.1
ENST00000361612.4
sulfatase 2
chr19_-_44031341 0.91 ENST00000600651.1
ethylmalonic encephalopathy 1
chr18_-_67872891 0.89 ENST00000454359.1
ENST00000437017.1
rotatin
chr15_+_71389281 0.88 ENST00000355327.3
thrombospondin, type I, domain containing 4
chr11_-_28129656 0.88 ENST00000263181.6
kinesin family member 18A
chr17_-_57229155 0.87 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chrX_+_7137475 0.86 ENST00000217961.4
steroid sulfatase (microsomal), isozyme S
chr10_+_75936444 0.86 ENST00000372734.3
ENST00000541550.1
adenosine kinase
chr20_-_46415297 0.85 ENST00000467815.1
ENST00000359930.4
sulfatase 2
chr1_+_86889769 0.84 ENST00000370565.4
chloride channel accessory 2
chr11_+_46403303 0.84 ENST00000407067.1
ENST00000395565.1
midkine (neurite growth-promoting factor 2)
chr19_+_38826477 0.83 ENST00000409410.2
ENST00000215069.4
catsper channel auxiliary subunit gamma
chr4_+_128702969 0.82 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chr18_+_56338750 0.82 ENST00000345724.3
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr17_+_26662730 0.80 ENST00000226225.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr17_+_33914276 0.79 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr9_-_21995249 0.79 ENST00000494262.1
cyclin-dependent kinase inhibitor 2A
chr11_+_126275477 0.77 ENST00000526727.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr12_+_93964158 0.76 ENST00000549206.1
suppressor of cytokine signaling 2
chr11_+_46403194 0.75 ENST00000395569.4
ENST00000395566.4
midkine (neurite growth-promoting factor 2)
chr19_+_38826415 0.73 ENST00000410018.1
ENST00000409235.3
catsper channel auxiliary subunit gamma
chr11_-_82708519 0.73 ENST00000534301.1
RAB30, member RAS oncogene family
chr9_-_21994597 0.71 ENST00000579755.1
cyclin-dependent kinase inhibitor 2A
chr1_+_117963209 0.71 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr9_-_21995300 0.71 ENST00000498628.2
cyclin-dependent kinase inhibitor 2A
chr10_+_5005598 0.70 ENST00000442997.1
aldo-keto reductase family 1, member C1
chrX_-_132095419 0.68 ENST00000370836.2
ENST00000521489.1
heparan sulfate 6-O-sulfotransferase 2
chr10_-_76995675 0.68 ENST00000469299.1
catechol-O-methyltransferase domain containing 1
chr22_+_38453207 0.67 ENST00000404072.3
ENST00000424694.1
protein interacting with PRKCA 1
chr22_+_38453378 0.66 ENST00000437453.1
ENST00000356976.3
protein interacting with PRKCA 1
chr1_-_212588157 0.65 ENST00000261455.4
ENST00000535273.1
transmembrane protein 206
chr10_-_76995769 0.64 ENST00000372538.3
catechol-O-methyltransferase domain containing 1
chr14_-_106830057 0.64 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr5_+_140782351 0.63 ENST00000573521.1
protocadherin gamma subfamily A, 9
chr10_+_13203543 0.63 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
minichromosome maintenance complex component 10
chr1_-_54304212 0.62 ENST00000540001.1
NDC1 transmembrane nucleoporin
chr11_+_2923499 0.61 ENST00000449793.2
solute carrier family 22, member 18
chr1_+_111770278 0.61 ENST00000369748.4
chitinase 3-like 2
chr13_-_114843416 0.61 ENST00000389544.4
RAS p21 protein activator 3
chr3_+_101568349 0.60 ENST00000326151.5
ENST00000326172.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr14_-_107095662 0.59 ENST00000390630.2
immunoglobulin heavy variable 4-61
chr11_+_2923423 0.58 ENST00000312221.5
solute carrier family 22, member 18
chr18_+_12308231 0.58 ENST00000590103.1
ENST00000591909.1
ENST00000586653.1
ENST00000592683.1
ENST00000590967.1
ENST00000591208.1
ENST00000591463.1
tubulin, beta 6 class V
chr6_+_64282447 0.57 ENST00000370650.2
ENST00000578299.1
protein tyrosine phosphatase type IVA, member 1
chr7_+_125078119 0.57 ENST00000458437.1
ENST00000415896.1
RP11-807H17.1
chr2_-_188378368 0.57 ENST00000392365.1
ENST00000435414.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_122750957 0.56 ENST00000451053.2
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr9_+_130213762 0.56 ENST00000300417.6
leucine rich repeat and sterile alpha motif containing 1
chr1_+_111770232 0.56 ENST00000369744.2
chitinase 3-like 2
chr9_+_130213774 0.56 ENST00000373324.4
ENST00000323301.4
leucine rich repeat and sterile alpha motif containing 1
chr12_-_118112196 0.56 ENST00000302438.5
kinase suppressor of ras 2
chr10_-_10836919 0.56 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
surfactant associated 1, pseudogene
chr1_+_35247859 0.55 ENST00000373362.3
gap junction protein, beta 3, 31kDa
chr17_-_40169659 0.54 ENST00000457167.4
DnaJ (Hsp40) homolog, subfamily C, member 7
chr11_+_2923619 0.54 ENST00000380574.1
solute carrier family 22, member 18
chr10_-_10836865 0.54 ENST00000446372.2
surfactant associated 1, pseudogene
chr6_+_31939608 0.54 ENST00000375331.2
ENST00000375333.2
serine/threonine kinase 19
chr18_+_56338618 0.54 ENST00000348428.3
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr9_-_21994344 0.54 ENST00000530628.2
ENST00000361570.3
cyclin-dependent kinase inhibitor 2A
chr16_+_56642489 0.53 ENST00000561491.1
metallothionein 2A
chr3_-_113465065 0.53 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr7_+_134528635 0.52 ENST00000445569.2
caldesmon 1
chr16_+_56642041 0.52 ENST00000245185.5
metallothionein 2A
chr2_-_172290482 0.51 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
methyltransferase like 8
chr10_-_95241951 0.51 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr10_-_95242044 0.51 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr1_-_11118896 0.50 ENST00000465788.1
spermidine synthase
chr11_+_28129795 0.49 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr7_-_86595190 0.49 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324-like
chr11_+_46402744 0.49 ENST00000533952.1
midkine (neurite growth-promoting factor 2)
chr3_+_50192537 0.49 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr14_-_106878083 0.49 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr3_+_50192499 0.48 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr16_-_2059797 0.48 ENST00000563630.1
zinc finger protein 598
chr17_-_5138099 0.48 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chrX_+_153607557 0.46 ENST00000369842.4
ENST00000369835.3
emerin
chr2_+_191792376 0.46 ENST00000409428.1
ENST00000409215.1
glutaminase
chr15_+_59903975 0.46 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr4_-_174255536 0.45 ENST00000446922.2
high mobility group box 2
chr14_+_74815116 0.44 ENST00000256362.4
vertebrae development associated
chr5_+_54455946 0.44 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr5_+_147443534 0.44 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr10_+_5005445 0.44 ENST00000380872.4
aldo-keto reductase family 1, member C1
chr15_-_34635314 0.43 ENST00000557912.1
ENST00000328848.4
NOP10 ribonucleoprotein
chr10_-_5046042 0.43 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr7_+_141490017 0.43 ENST00000247883.4
taste receptor, type 2, member 5
chr11_-_62368696 0.43 ENST00000527204.1
metastasis associated 1 family, member 2
chr5_+_34757309 0.42 ENST00000397449.1
retinoic acid induced 14
chr1_-_221915418 0.42 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr1_+_153330322 0.42 ENST00000368738.3
S100 calcium binding protein A9
chr16_-_2059748 0.42 ENST00000562103.1
ENST00000431526.1
zinc finger protein 598
chr14_-_106478603 0.42 ENST00000390596.2
immunoglobulin heavy variable 4-4
chr16_-_838329 0.42 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RNA pseudouridylate synthase domain containing 1
chr22_-_45809446 0.41 ENST00000357450.4
structural maintenance of chromosomes 1B
chr7_+_127233689 0.40 ENST00000265825.5
ENST00000420086.2
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr13_+_52586517 0.40 ENST00000523764.1
ENST00000521508.1
ALG11, alpha-1,2-mannosyltransferase
chr17_+_7211656 0.39 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr3_-_197476560 0.38 ENST00000273582.5
KIAA0226
chr1_+_73771844 0.38 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
chr7_-_44613494 0.38 ENST00000431640.1
ENST00000258772.5
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr5_-_36242119 0.37 ENST00000511088.1
ENST00000282512.3
ENST00000506945.1
NAD kinase 2, mitochondrial
chr5_-_37371163 0.37 ENST00000513532.1
nucleoporin 155kDa
chr6_+_64281906 0.37 ENST00000370651.3
protein tyrosine phosphatase type IVA, member 1
chr1_+_190448095 0.36 ENST00000424735.1
RP11-547I7.2
chr20_-_62203808 0.36 ENST00000467148.1
helicase with zinc finger 2, transcriptional coactivator
chr5_-_137514617 0.36 ENST00000254900.5
bromodomain containing 8
chr11_+_47270436 0.36 ENST00000395397.3
ENST00000405576.1
nuclear receptor subfamily 1, group H, member 3
chr6_-_49755019 0.36 ENST00000304801.3
phosphoglycerate kinase 2
chr3_-_113897899 0.36 ENST00000383673.2
ENST00000295881.7
dopamine receptor D3
chr1_+_109656532 0.36 ENST00000531664.1
ENST00000534476.1
KIAA1324
chr11_+_31391381 0.35 ENST00000465995.1
ENST00000536040.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr4_-_89080003 0.35 ENST00000237612.3
ATP-binding cassette, sub-family G (WHITE), member 2
chr6_+_116601265 0.35 ENST00000452085.3
dermatan sulfate epimerase
chr12_-_118797475 0.35 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr17_-_7082861 0.34 ENST00000269299.3
asialoglycoprotein receptor 1
chrX_+_149009941 0.34 ENST00000535454.1
ENST00000542674.1
ENST00000286482.1
melanoma antigen family A, 8
chr16_+_2059872 0.34 ENST00000567649.1
neuropeptide W
chr20_-_61274656 0.34 ENST00000370520.3
HCG2018282; Uncharacterized protein
chr15_-_22473353 0.34 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr11_+_47270475 0.34 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
nuclear receptor subfamily 1, group H, member 3
chrX_-_106146547 0.34 ENST00000276173.4
ENST00000411805.1
ripply transcriptional repressor 1
chr3_-_183966717 0.33 ENST00000446569.1
ENST00000418734.2
ENST00000397676.3
ALG3, alpha-1,3- mannosyltransferase
chr1_-_39325431 0.33 ENST00000373001.3
Ras-related GTP binding C
chr8_-_28243934 0.32 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr12_-_76478446 0.32 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chrX_-_48814810 0.32 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTU domain containing 5
chr9_-_139965000 0.32 ENST00000409687.3
suppressor APC domain containing 2
chr2_+_211421262 0.32 ENST00000233072.5
carbamoyl-phosphate synthase 1, mitochondrial
chr7_-_27187393 0.32 ENST00000222728.3
homeobox A6
chr14_-_106791536 0.31 ENST00000390613.2
immunoglobulin heavy variable 3-30
chr3_-_113464906 0.31 ENST00000477813.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_+_151171012 0.31 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr4_-_157892055 0.31 ENST00000422544.2
platelet derived growth factor C
chr10_+_90354503 0.31 ENST00000531458.1
lipase, family member J
chr22_+_25003568 0.30 ENST00000447416.1
gamma-glutamyltransferase 1
chr15_+_45694523 0.30 ENST00000305560.6
spermatogenesis associated 5-like 1
chr17_-_80408569 0.30 ENST00000577696.1
ENST00000577471.1
ENST00000582545.2
ENST00000437807.2
ENST00000583617.1
ENST00000578913.1
ENST00000336995.7
ENST00000577834.1
ENST00000342572.8
ENST00000585064.1
ENST00000585080.1
ENST00000578919.1
ENST00000306645.5
ENST00000434650.2
chromosome 17 open reading frame 62
chr5_-_37371278 0.29 ENST00000231498.3
nucleoporin 155kDa
chr12_+_93096759 0.29 ENST00000544406.2
chromosome 12 open reading frame 74
chr7_-_108168580 0.29 ENST00000453085.1
patatin-like phospholipase domain containing 8
chr14_+_96722539 0.29 ENST00000553356.1
bradykinin receptor B1
chr8_-_39695764 0.29 ENST00000265708.4
ADAM metallopeptidase domain 2
chr15_+_62359175 0.29 ENST00000355522.5
C2 calcium-dependent domain containing 4A
chr11_+_695380 0.29 ENST00000397510.3
transmembrane protein 80
chr6_+_155470243 0.28 ENST00000456877.2
ENST00000528391.2
T-cell lymphoma invasion and metastasis 2
chr3_+_48956249 0.28 ENST00000452882.1
ENST00000430423.1
ENST00000356401.4
ENST00000449376.1
ENST00000420814.1
ENST00000449729.1
ENST00000433170.1
ariadne RBR E3 ubiquitin protein ligase 2
chr17_-_34308524 0.28 ENST00000293275.3
chemokine (C-C motif) ligand 16
chr17_+_38474489 0.28 ENST00000394089.2
ENST00000425707.3
retinoic acid receptor, alpha
chr16_-_28222797 0.28 ENST00000569951.1
ENST00000565698.1
exportin 6
chr5_+_140792614 0.28 ENST00000398610.2
protocadherin gamma subfamily A, 10
chr16_-_28223166 0.28 ENST00000304658.5
exportin 6
chr2_-_61765315 0.27 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chrX_+_105937068 0.27 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chrX_+_30671476 0.27 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
glycerol kinase
chr12_+_93096619 0.27 ENST00000397833.3
chromosome 12 open reading frame 74
chr2_+_11696464 0.26 ENST00000234142.5
growth regulation by estrogen in breast cancer 1
chr2_-_10952832 0.26 ENST00000540494.1
protein disulfide isomerase family A, member 6
chr8_-_54755459 0.25 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr19_-_47220335 0.25 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
protein kinase D2
chr1_-_91870292 0.25 ENST00000455133.1
ENST00000370424.3
ENST00000427444.1
ENST00000448819.1
ENST00000370425.3
ENST00000294696.5
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr17_-_73401728 0.25 ENST00000316804.5
ENST00000316615.5
growth factor receptor-bound protein 2
chr6_-_33756867 0.25 ENST00000293760.5
LEM domain containing 2
chr11_+_695614 0.25 ENST00000608174.1
ENST00000397512.3
transmembrane protein 80
chr14_+_72399833 0.25 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr17_-_73401567 0.25 ENST00000392562.1
growth factor receptor-bound protein 2
chr2_-_99870744 0.25 ENST00000409238.1
ENST00000423800.1
lysozyme G-like 2
chr12_+_5153085 0.25 ENST00000252321.3
potassium voltage-gated channel, shaker-related subfamily, member 5
chr11_+_128563652 0.24 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr16_+_30935896 0.24 ENST00000562319.1
ENST00000380310.2
F-box and leucine-rich repeat protein 19
chr16_+_1730338 0.24 ENST00000566691.1
ENST00000382710.4
hematological and neurological expressed 1-like
chr7_-_151433342 0.24 ENST00000433631.2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr7_-_151433393 0.23 ENST00000492843.1
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr2_-_88427568 0.23 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chrX_+_151903253 0.23 ENST00000452779.2
ENST00000370291.2
chondrosarcoma associated gene 1
chr3_+_197476621 0.23 ENST00000241502.4
forty-two-three domain containing 1
chr17_+_57297807 0.22 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
glycerophosphodiester phosphodiesterase domain containing 1
chr11_+_695787 0.22 ENST00000526170.1
ENST00000488769.1
transmembrane protein 80

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.4 1.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 2.1 GO:0030421 defecation(GO:0030421)
0.3 0.9 GO:0044209 AMP salvage(GO:0044209)
0.3 1.4 GO:0060356 leucine import(GO:0060356)
0.3 1.4 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 2.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 2.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.9 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 2.8 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 1.6 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.9 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 1.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 0.6 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2 1.8 GO:0046618 drug export(GO:0046618)
0.2 1.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 1.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 1.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 2.8 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.2 0.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.9 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 1.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.0 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.7 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.4 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 1.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 1.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.9 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 3.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 1.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.2 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.8 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 2.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.7 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 1.2 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.9 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 1.6 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.4 GO:0032196 transposition(GO:0032196)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.8 GO:0097503 sialylation(GO:0097503)
0.0 1.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 2.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.7 GO:0010761 fibroblast migration(GO:0010761)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0032449 CBM complex(GO:0032449)
0.2 2.0 GO:0035976 AP1 complex(GO:0035976)
0.2 2.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 0.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.2 1.6 GO:0036128 CatSper complex(GO:0036128)
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 0.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.0 GO:0097443 sorting endosome(GO:0097443)
0.1 0.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.4 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 2.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.7 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.9 GO:0071437 microvillus membrane(GO:0031528) invadopodium(GO:0071437)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 3.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 3.2 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.3 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.7 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.3 1.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.3 1.1 GO:0047023 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.3 1.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 2.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.7 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 0.5 GO:0004766 spermidine synthase activity(GO:0004766)
0.2 0.8 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.2 0.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.4 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.7 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 2.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0004803 transposase activity(GO:0004803)
0.1 0.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 1.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.1 GO:0004568 chitinase activity(GO:0004568)
0.1 1.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 1.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.2 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.9 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.7 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.3 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.4 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.5 PID AURORA B PATHWAY Aurora B signaling
0.1 2.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 ST ADRENERGIC Adrenergic Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 REACTOME KINESINS Genes involved in Kinesins
0.1 3.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules