ISMARA results: TFDP1

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFDP1

Z-value: 0.85

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Transcription factors associated with TFDP1

Gene Symbol	Gene ID	Gene Info
TFDP1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000198176.8	transcription factor Dp-1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TFDP1	hg19_v2_chr13_+_114239588_114239752	0.67	4.3e-05	Click!

Activity profile of TFDP1 motif

Sorted Z-values of TFDP1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_83351005 Show fit	1.77	ENST00000295470.5	HNRNPDL Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein D-like
chr6_+_20403997 Show fit	1.35	ENST00000535432.1	E2F3 Ensembl NCBI GeneCards UniProt NextProt Show fit	E2F transcription factor 3
chr2_+_174219548 Show fit	1.34	ENST00000347703.3 ENST00000392567.2 ENST00000306721.3 ENST00000410101.3 ENST00000410019.3	CDCA7 Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle associated 7
chr1_+_212208919 Show fit	1.33	ENST00000366991.4 ENST00000542077.1	DTL Ensembl NCBI GeneCards UniProt NextProt Show fit	denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr6_-_86352982 Show fit	1.29	ENST00000369622.3	SYNCRIP Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_-_64851496 Show fit	1.26	ENST00000404147.3 ENST00000275517.3	CDCA5 Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle associated 5
chr16_+_46723552 Show fit	1.24	ENST00000219097.2 ENST00000568364.2	ORC6 Ensembl NCBI GeneCards UniProt NextProt Show fit	origin recognition complex, subunit 6
chr17_+_30814707 Show fit	1.16	ENST00000584792.1	CDK5R1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr10_+_105127704 Show fit	1.06	ENST00000369839.3 ENST00000351396.4	TAF5 Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
chr11_-_118966167 Show fit	1.06	ENST00000530167.1	H2AFX Ensembl NCBI GeneCards UniProt NextProt Show fit	H2A histone family, member X

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of TFDP1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	3.3	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	2.6	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1	2.4	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.5	2.3	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.3	1.9	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2	1.9	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	1.9	GO:0043486	histone exchange(GO:0043486)
0.2	1.8	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	1.8	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)

Showing 1 to 10 of 448 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.6	GO:0000922	spindle pole(GO:0000922)
0.0	3.1	GO:0072686	mitotic spindle(GO:0072686)
0.2	2.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	1.9	GO:0097452	GAIT complex(GO:0097452)
0.1	1.9	GO:0000812	Swr1 complex(GO:0000812)
0.2	1.8	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.6	1.7	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.4	1.7	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	1.7	GO:0042555	MCM complex(GO:0042555)
0.1	1.6	GO:0005642	annulate lamellae(GO:0005642)

Showing 1 to 10 of 173 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	2.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.2	2.1	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.1	2.1	GO:0005521	lamin binding(GO:0005521)
0.0	2.0	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	1.9	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	1.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.2	1.8	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	1.8	GO:0008143	poly(A) binding(GO:0008143)
0.0	1.8	GO:0019003	GDP binding(GO:0019003)

Showing 1 to 10 of 250 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.8	PID E2F PATHWAY	E2F transcription factor network
0.1	4.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	3.6	PID AURORA B PATHWAY	Aurora B signaling
0.1	3.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	3.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	2.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	1.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	1.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.5	PID CXCR4 PATHWAY	CXCR4-mediated signaling events

Showing 1 to 10 of 43 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.8	REACTOME LAGGING STRAND SYNTHESIS	Genes involved in Lagging Strand Synthesis
0.2	4.4	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.3	3.8	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	2.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	2.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	2.5	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	2.2	REACTOME KINESINS	Genes involved in Kinesins
0.1	2.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	2.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition

Showing 1 to 10 of 81 entries

Results for TFDP1

Z-value: 0.85

Motif logo

Transcription factors associated with TFDP1

Activity-expression correlation:

Activity profile of TFDP1 motif

Sorted Z-values of TFDP1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TFDP1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: