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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.82

Motif logo

Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
ENSG00000105967.11 transcription factor EC
ENSG00000187098.10 melanocyte inducing transcription factor
ENSG00000133794.13 aryl hydrocarbon receptor nuclear translocator like
ENSG00000123095.5 basic helix-loop-helix family member e41

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MITFhg19_v2_chr3_+_69985792_69985874-0.422.1e-02Click!
BHLHE41hg19_v2_chr12_-_26278030_262780600.281.3e-01Click!
ARNTLhg19_v2_chr11_+_13299186_13299432-0.193.0e-01Click!
TFEChg19_v2_chr7_-_115670792_1156707980.144.6e-01Click!

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_67159416 3.22 ENST00000307980.2
ENST00000544620.1
RAD9 homolog A (S. pombe)
chrY_+_22918021 2.70 ENST00000288666.5
ribosomal protein S4, Y-linked 2
chrY_+_2709527 2.52 ENST00000250784.8
ribosomal protein S4, Y-linked 1
chr1_-_42921915 2.30 ENST00000372565.3
ENST00000433602.2
zinc finger, MYND-type containing 12
chrY_+_2709906 2.24 ENST00000430575.1
ribosomal protein S4, Y-linked 1
chr6_+_151646800 2.06 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chrY_+_15016725 1.69 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chrY_+_15016013 1.58 ENST00000360160.4
ENST00000454054.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chrX_-_100914781 1.51 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
armadillo repeat containing, X-linked 2
chr7_+_36429409 1.48 ENST00000265748.2
anillin, actin binding protein
chr7_+_36429424 1.48 ENST00000396068.2
anillin, actin binding protein
chr1_-_68962805 1.45 ENST00000370966.5
DEP domain containing 1
chr1_+_11866207 1.43 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr1_+_154193325 1.43 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr1_-_68962782 1.40 ENST00000456315.2
DEP domain containing 1
chr17_+_72270380 1.36 ENST00000582036.1
ENST00000307504.5
dynein, axonemal, intermediate chain 2
chr17_+_72270429 1.26 ENST00000311014.6
dynein, axonemal, intermediate chain 2
chr3_-_19988462 1.23 ENST00000344838.4
EF-hand domain family, member B
chr17_-_7137582 1.22 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr19_+_14544099 1.17 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr17_-_7137857 1.13 ENST00000005340.5
dishevelled segment polarity protein 2
chr2_+_240323439 1.13 ENST00000428471.1
ENST00000413029.1
Uncharacterized protein
chr12_-_111358372 1.11 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr1_-_26233423 1.10 ENST00000357865.2
stathmin 1
chr19_-_49137762 1.03 ENST00000593500.1
D site of albumin promoter (albumin D-box) binding protein
chr5_-_133706695 1.03 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr11_+_118938485 1.01 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr12_+_93964746 0.98 ENST00000536696.2
suppressor of cytokine signaling 2
chr19_-_49137790 0.97 ENST00000599385.1
D site of albumin promoter (albumin D-box) binding protein
chr19_+_1275917 0.96 ENST00000469144.1
chromosome 19 open reading frame 24
chr19_+_5720666 0.96 ENST00000381624.3
ENST00000381614.2
catsper channel auxiliary subunit delta
chr6_+_151561506 0.91 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr16_+_15737124 0.91 ENST00000396355.1
ENST00000396353.2
nudE neurodevelopment protein 1
chr18_+_56530794 0.89 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
zinc finger protein 532
chr19_+_49458107 0.88 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr12_-_2986107 0.88 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr17_+_62223320 0.86 ENST00000580828.1
ENST00000582965.1
small nucleolar RNA, H/ACA box 76
chr2_-_160143084 0.82 ENST00000409990.3
WD repeat, sterile alpha motif and U-box domain containing 1
chr19_-_11545920 0.82 ENST00000356392.4
ENST00000591179.1
coiled-coil domain containing 151
chr10_+_69644404 0.82 ENST00000212015.6
sirtuin 1
chr2_-_160143242 0.81 ENST00000359774.4
WD repeat, sterile alpha motif and U-box domain containing 1
chr2_-_160143059 0.80 ENST00000392796.3
WD repeat, sterile alpha motif and U-box domain containing 1
chr10_+_101542462 0.79 ENST00000370449.4
ENST00000370434.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr2_-_160143158 0.79 ENST00000409124.1
ENST00000358147.4
WD repeat, sterile alpha motif and U-box domain containing 1
chr22_-_42342692 0.79 ENST00000404067.1
ENST00000402338.1
centromere protein M
chrX_-_34675391 0.79 ENST00000275954.3
transmembrane protein 47
chr19_-_41256207 0.77 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr19_-_11688500 0.74 ENST00000433365.2
acid phosphatase 5, tartrate resistant
chr15_-_72668185 0.73 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr22_-_42343117 0.73 ENST00000407253.3
ENST00000215980.5
centromere protein M
chr8_+_75896731 0.70 ENST00000262207.4
cysteine-rich secretory protein LCCL domain containing 1
chr12_-_123849374 0.67 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr14_-_94443105 0.66 ENST00000555019.1
ankyrin repeat and SOCS box containing 2
chr3_+_134204551 0.65 ENST00000332047.5
ENST00000354446.3
centrosomal protein 63kDa
chr6_+_87865262 0.65 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chrX_-_100662881 0.63 ENST00000218516.3
galactosidase, alpha
chr16_-_88923285 0.63 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
galactosamine (N-acetyl)-6-sulfate sulfatase
chr11_-_18343669 0.63 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
Hermansky-Pudlak syndrome 5
chr7_+_97361218 0.62 ENST00000319273.5
tachykinin, precursor 1
chr16_-_23160591 0.61 ENST00000219689.7
ubiquitin specific peptidase 31
chr3_-_122512619 0.61 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr20_-_2821271 0.59 ENST00000448755.1
ENST00000360652.2
PC-esterase domain containing 1A
chr3_+_134204881 0.58 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
centrosomal protein 63kDa
chr12_+_12878829 0.57 ENST00000326765.6
apolipoprotein L domain containing 1
chr2_-_47572105 0.56 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr19_-_5719860 0.56 ENST00000590729.1
lon peptidase 1, mitochondrial
chr3_+_134205000 0.56 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
centrosomal protein 63kDa
chr9_-_34048873 0.55 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
ubiquitin associated protein 2
chr20_-_2821756 0.54 ENST00000356872.3
ENST00000439542.1
PC-esterase domain containing 1A
chr2_+_187558698 0.54 ENST00000304698.5
family with sequence similarity 171, member B
chr6_-_33385854 0.54 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr19_+_10765003 0.53 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr3_-_134204815 0.53 ENST00000514612.1
ENST00000510994.1
ENST00000354910.5
anaphase promoting complex subunit 13
chr15_-_72668805 0.53 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr15_+_41913690 0.53 ENST00000563576.1
MGA, MAX dimerization protein
chr9_-_100684845 0.52 ENST00000375119.3
chromosome 9 open reading frame 156
chr11_+_95523823 0.52 ENST00000538658.1
centrosomal protein 57kDa
chr19_+_10764937 0.52 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr1_-_27226928 0.51 ENST00000361720.5
G patch domain containing 3
chr19_+_4007644 0.51 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr6_-_33385823 0.50 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr2_+_46926048 0.50 ENST00000306503.5
suppressor of cytokine signaling 5
chr15_+_82555125 0.50 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
family with sequence similarity 154, member B
chr16_+_31044413 0.50 ENST00000394998.1
syntaxin 4
chr6_-_33385655 0.49 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr19_+_41256764 0.49 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
small nuclear ribonucleoprotein polypeptide A
chr3_-_189840223 0.48 ENST00000427335.2
leprecan-like 1
chr11_-_113746277 0.46 ENST00000003302.4
ENST00000545540.1
ubiquitin specific peptidase 28
chr6_+_151561085 0.46 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr18_-_29522989 0.46 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
trafficking protein particle complex 8
chr2_-_220108309 0.46 ENST00000409640.1
galactosidase, beta 1-like
chr19_-_5720123 0.45 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
lon peptidase 1, mitochondrial
chr19_-_5720248 0.45 ENST00000360614.3
lon peptidase 1, mitochondrial
chr2_+_27309605 0.44 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
ketohexokinase (fructokinase)
chr6_-_84937314 0.43 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr5_+_68463043 0.43 ENST00000508407.1
ENST00000505500.1
cyclin B1
chr7_+_97361388 0.42 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr6_-_33385902 0.41 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chrX_-_100872911 0.41 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
armadillo repeat containing, X-linked 6
chr4_+_128651530 0.41 ENST00000281154.4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr11_-_19263145 0.41 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8
chr6_+_7590413 0.41 ENST00000342415.5
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr10_+_99344071 0.40 ENST00000370647.4
ENST00000370646.4
4-hydroxy-2-oxoglutarate aldolase 1
chr5_+_68462944 0.40 ENST00000506572.1
cyclin B1
chr16_-_57219721 0.40 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
family with sequence similarity 192, member A
chr6_-_33385870 0.40 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr11_-_113746212 0.39 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
ubiquitin specific peptidase 28
chr16_+_31044812 0.39 ENST00000313843.3
syntaxin 4
chr1_+_17248418 0.39 ENST00000375541.5
ciliary rootlet coiled-coil, rootletin
chr15_+_89182178 0.38 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr10_-_25305011 0.38 ENST00000331161.4
ENST00000376363.1
enkurin, TRPC channel interacting protein
chrY_-_15591485 0.38 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chrX_-_101397433 0.38 ENST00000372774.3
transcription elongation factor A (SII)-like 6
chr3_+_130745769 0.37 ENST00000412440.2
NIMA-related kinase 11
chr17_-_76124711 0.37 ENST00000306591.7
ENST00000590602.1
transmembrane channel-like 6
chr6_-_43337180 0.37 ENST00000318149.3
ENST00000361428.2
zinc finger protein 318
chr3_-_48057890 0.36 ENST00000434267.1
microtubule-associated protein 4
chr22_+_35776828 0.36 ENST00000216117.8
heme oxygenase (decycling) 1
chrX_+_101975643 0.35 ENST00000361229.4
basic helix-loop-helix domain containing, class B, 9
chrX_+_101975619 0.35 ENST00000457056.1
basic helix-loop-helix domain containing, class B, 9
chr12_+_51632666 0.35 ENST00000604900.1
DAZ associated protein 2
chr16_+_9185450 0.35 ENST00000327827.7
chromosome 16 open reading frame 72
chr12_+_93964158 0.34 ENST00000549206.1
suppressor of cytokine signaling 2
chr12_+_122356488 0.34 ENST00000397454.2
WD repeat domain 66
chr17_-_76124812 0.34 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
transmembrane channel-like 6
chr19_-_49016418 0.34 ENST00000270238.3
lemur tyrosine kinase 3
chr8_+_133787586 0.33 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHD finger protein 20-like 1
chr8_+_17780346 0.33 ENST00000325083.8
pericentriolar material 1
chrX_+_128913906 0.33 ENST00000356892.3
SAM and SH3 domain containing 3
chr17_+_42977122 0.33 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr11_+_60197069 0.33 ENST00000528905.1
ENST00000528093.1
membrane-spanning 4-domains, subfamily A, member 5
chr3_+_148847371 0.32 ENST00000296051.2
ENST00000460120.1
Hermansky-Pudlak syndrome 3
chr18_+_9136758 0.32 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr7_-_155089251 0.32 ENST00000609974.1
AC144652.1
chr15_-_31393910 0.32 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
transient receptor potential cation channel, subfamily M, member 1
chr17_-_5015129 0.32 ENST00000575898.1
ENST00000416429.2
zinc finger protein 232
chr15_+_89181974 0.31 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr1_-_26232951 0.31 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr9_+_133971863 0.31 ENST00000372309.3
allograft inflammatory factor 1-like
chr1_-_217250231 0.31 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr2_-_197036289 0.30 ENST00000263955.4
serine/threonine kinase 17b
chr16_+_2570340 0.30 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr7_+_73242069 0.30 ENST00000435050.1
claudin 4
chr17_-_6915646 0.30 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chr17_-_7197881 0.30 ENST00000007699.5
Y box binding protein 2
chr9_-_79307096 0.30 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
prune homolog 2 (Drosophila)
chr2_-_220083671 0.29 ENST00000439002.2
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr20_-_44519839 0.29 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr11_+_7534999 0.29 ENST00000528947.1
ENST00000299492.4
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_-_9734004 0.29 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr7_+_142919130 0.29 ENST00000408947.3
taste receptor, type 2, member 40
chr8_-_82754427 0.29 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
sorting nexin 16
chr19_-_11688447 0.29 ENST00000590420.1
acid phosphatase 5, tartrate resistant
chr17_+_62503147 0.28 ENST00000553412.1
centrosomal protein 95kDa
chr7_+_143013198 0.28 ENST00000343257.2
chloride channel, voltage-sensitive 1
chr1_+_199996702 0.28 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr8_-_103425047 0.28 ENST00000520539.1
ubiquitin protein ligase E3 component n-recognin 5
chr12_+_7023491 0.28 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr18_-_46987000 0.28 ENST00000442713.2
ENST00000269445.6
dymeclin
chr4_-_89978299 0.28 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
family with sequence similarity 13, member A
chr19_-_12886327 0.27 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
hook microtubule-tethering protein 2
chr12_+_7023735 0.27 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr2_-_128643496 0.27 ENST00000272647.5
AMMECR1-like
chr8_-_66701319 0.27 ENST00000379419.4
phosphodiesterase 7A
chr22_-_39096661 0.27 ENST00000216039.5
Josephin domain containing 1
chr2_-_220083692 0.27 ENST00000265316.3
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr3_+_130745688 0.27 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NIMA-related kinase 11
chr2_-_133427767 0.27 ENST00000397463.2
LY6/PLAUR domain containing 1
chr5_+_78532003 0.26 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr16_-_5083589 0.26 ENST00000563578.1
ENST00000562346.2
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr7_-_30029367 0.26 ENST00000242059.5
secernin 1
chr4_-_23891658 0.26 ENST00000507380.1
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_45307817 0.26 ENST00000020926.3
synaptotagmin XIII
chr19_+_39903185 0.26 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_-_15236173 0.26 ENST00000527093.1
ilvB (bacterial acetolactate synthase)-like
chr9_+_34646651 0.26 ENST00000378842.3
galactose-1-phosphate uridylyltransferase
chr6_+_64345698 0.25 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHD finger protein 3
chr9_+_34646624 0.25 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr6_+_7107999 0.25 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr6_+_127587755 0.25 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr21_-_46330545 0.25 ENST00000320216.6
ENST00000397852.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_80657292 0.25 ENST00000369816.4
ELOVL fatty acid elongase 4
chr9_+_133971909 0.25 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
allograft inflammatory factor 1-like
chr14_+_77564440 0.25 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
CLOCK-interacting pacemaker
chr12_+_57916466 0.25 ENST00000355673.3
methyl-CpG binding domain protein 6
chr8_+_67039278 0.25 ENST00000276573.7
ENST00000350034.4
tripartite motif containing 55
chr11_-_60719213 0.24 ENST00000227880.3
solute carrier family 15 (oligopeptide transporter), member 3
chr7_-_47621736 0.24 ENST00000311160.9
tensin 3
chrX_+_146993449 0.24 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chr6_+_127588020 0.24 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr7_+_99746514 0.24 ENST00000341942.5
ENST00000441173.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr16_-_5083917 0.24 ENST00000312251.3
ENST00000381955.3
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr19_-_45004556 0.24 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
zinc finger protein 180
chr17_-_35969409 0.23 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma
chr16_+_28986134 0.23 ENST00000352260.7
spinster homolog 1 (Drosophila)
chr7_-_30029574 0.23 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
secernin 1
chr14_-_20923195 0.23 ENST00000206542.4
O-sialoglycoprotein endopeptidase
chr1_-_28969517 0.23 ENST00000263974.4
ENST00000373824.4
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr1_+_11796126 0.23 ENST00000376637.3
angiotensin II receptor-associated protein
chr4_+_39184024 0.23 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WD repeat domain 19

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.6 2.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.5 3.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.5 1.5 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.3 1.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.3 0.9 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 0.9 GO:1902339 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3 0.8 GO:0046680 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.3 0.8 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 0.8 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.3 1.8 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 1.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 1.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 3.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 1.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 1.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 3.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.5 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.2 0.5 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 1.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 1.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.3 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.9 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 1.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.1 GO:0034059 response to anoxia(GO:0034059)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 0.4 GO:2000301 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.1 0.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.9 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.2 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.2 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.2 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.1 0.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.2 GO:1990169 detoxification of copper ion(GO:0010273) cellular response to lead ion(GO:0071284) stress response to copper ion(GO:1990169)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.3 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.0 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 1.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.0 2.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0048565 digestive tract development(GO:0048565)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 1.5 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 4.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0072019 isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.2 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 1.4 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.4 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.2 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.1 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 0.1 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0012502 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.6 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.0 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0010042 response to manganese ion(GO:0010042)
0.0 0.3 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.1 GO:0044256 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.1 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.0 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0042921 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 1.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.0 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) regulation of melanosome transport(GO:1902908) positive regulation of melanosome transport(GO:1902910)
0.0 0.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.0 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.0 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.5 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 3.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 1.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 2.6 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.0 GO:0036128 CatSper complex(GO:0036128)
0.1 0.3 GO:0001534 radial spoke(GO:0001534)
0.1 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.3 GO:0019034 viral replication complex(GO:0019034)
0.1 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.9 GO:0000322 storage vacuole(GO:0000322)
0.1 0.3 GO:0097447 dendritic tree(GO:0097447)
0.1 6.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 2.5 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 2.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 1.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.0 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.5 1.5 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.3 0.9 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 0.8 GO:0043398 HLH domain binding(GO:0043398)
0.2 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 3.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.6 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.5 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 1.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.4 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 7.4 GO:0019843 rRNA binding(GO:0019843)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.2 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 2.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 2.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0035240 dopamine binding(GO:0035240)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.1 PID ATM PATHWAY ATM pathway
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.4 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME HIV LIFE CYCLE Genes involved in HIV Life Cycle
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels