Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for TFEC_MITF_ARNTL_BHLHE41
Z-value: 0.82
Motif logo
Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000105967.11 | transcription factor EC | |
| ENSG00000187098.10 | melanocyte inducing transcription factor | |
| ENSG00000133794.13 | aryl hydrocarbon receptor nuclear translocator like | |
| ENSG00000123095.5 | basic helix-loop-helix family member e41 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MITF | hg19_v2_chr3_+_69985792_69985874 | -0.42 | 2.1e-02 | Click! |
| BHLHE41 | hg19_v2_chr12_-_26278030_26278060 | 0.28 | 1.3e-01 | Click! |
| ARNTL | hg19_v2_chr11_+_13299186_13299432 | -0.19 | 3.0e-01 | Click! |
| TFEC | hg19_v2_chr7_-_115670792_115670798 | 0.14 | 4.6e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TFEC_MITF_ARNTL_BHLHE41
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.7 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.2 | 3.9 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.5 | 3.7 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.2 | 3.4 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 1.0 | 3.0 | GO:1904170 | regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172) |
| 0.0 | 2.5 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.6 | 2.4 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.3 | 1.8 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.1 | 1.6 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 1.6 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.4 | 3.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.6 | 3.0 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.0 | 2.8 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.2 | 2.6 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 2.5 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 2.5 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 1.5 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.5 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 1.1 | GO:0097512 | cardiac myofibril(GO:0097512) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.4 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.2 | 3.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.5 | 3.2 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 2.6 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 2.5 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 2.2 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 1.9 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.5 | 1.5 | GO:0070362 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
| 0.2 | 1.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 1.3 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 2.4 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 2.1 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.8 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.4 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 1.1 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 1.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 0.9 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.9 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 4.4 | REACTOME G2 M CHECKPOINTS | Genes involved in G2/M Checkpoints |
| 0.1 | 2.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 2.3 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.3 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 1.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.3 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 1.2 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 1.1 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |