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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TLX2

Z-value: 0.84

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Transcription factors associated with TLX2

Gene Symbol Gene ID Gene Info
TLX2
ENSG00000115297.9 T cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TLX2hg19_v2_chr2_+_74741569_747416200.135.0e-01Click!

Activity profile of TLX2 motif

Sorted Z-values of TLX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102928009 4.89 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr8_+_86376081 3.90 ENST00000285379.5
CA2
carbonic anhydrase II
chr14_+_54863739 3.19 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chr14_+_54863667 2.92 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chr2_+_10262857 2.90 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr14_+_54863682 2.89 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
CDKN3
cyclin-dependent kinase inhibitor 3
chr1_-_17304771 2.61 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr4_+_17812525 2.44 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr11_+_69924639 2.28 ENST00000538023.1
ENST00000398543.2
ANO1
anoctamin 1, calcium activated chloride channel
chr1_+_152881014 2.21 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr1_+_152486950 2.16 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr10_+_88718397 2.02 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr11_-_123065989 2.02 ENST00000448775.2
CLMP
CXADR-like membrane protein
chr6_+_24775641 1.96 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr1_-_24469602 1.93 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr22_+_31477296 1.92 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
SMTN
smoothelin
chr10_+_88718314 1.88 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr4_+_156680518 1.85 ENST00000513437.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr3_+_121796697 1.72 ENST00000482356.1
ENST00000393627.2
CD86
CD86 molecule
chr2_-_190044480 1.68 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr10_-_90712520 1.67 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr4_+_156680143 1.67 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr19_+_676385 1.66 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr17_-_76899275 1.59 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chr7_+_155090271 1.57 ENST00000476756.1
INSIG1
insulin induced gene 1
chr4_+_156680153 1.50 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr3_+_121774202 1.48 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr3_-_42744312 1.46 ENST00000416756.1
ENST00000441594.1
HHATL
hedgehog acyltransferase-like
chr2_-_72375167 1.45 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr19_+_47104553 1.45 ENST00000598871.1
ENST00000594523.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr19_-_11266471 1.40 ENST00000592540.1
SPC24
SPC24, NDC80 kinetochore complex component
chr14_+_65171315 1.38 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr14_+_55034599 1.33 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr2_+_192543153 1.32 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr12_-_99038732 1.30 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr1_+_86889769 1.29 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr20_-_1373606 1.28 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr10_-_75401500 1.23 ENST00000359322.4
MYOZ1
myozenin 1
chr9_+_35673853 1.22 ENST00000378357.4
CA9
carbonic anhydrase IX
chr8_+_22423219 1.22 ENST00000523965.1
ENST00000521554.1
SORBS3
sorbin and SH3 domain containing 3
chr4_+_1873100 1.22 ENST00000508803.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr10_+_76871229 1.19 ENST00000372690.3
SAMD8
sterile alpha motif domain containing 8
chr1_+_151030234 1.16 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr9_+_36572851 1.15 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr14_+_65171099 1.14 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_+_113403434 1.12 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr21_-_38639601 1.10 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
DSCR3
Down syndrome critical region gene 3
chr8_+_27182862 1.09 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr21_-_16437126 1.09 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr21_-_16437255 1.07 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr11_+_35160709 1.06 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44
CD44 molecule (Indian blood group)
chr8_+_27183033 1.06 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr9_+_139847347 1.04 ENST00000371632.3
LCN12
lipocalin 12
chr14_-_57272366 1.03 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr19_-_51512804 1.03 ENST00000594211.1
ENST00000376832.4
KLK9
kallikrein-related peptidase 9
chr9_+_75263565 1.02 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr1_+_16083154 1.02 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr10_-_33623564 1.02 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr10_-_103347883 1.01 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL
polymerase (DNA directed), lambda
chr8_+_26435359 1.01 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr19_-_11688500 0.99 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr19_-_11688447 0.96 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr15_-_82555000 0.96 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1
elongation factor Tu GTP binding domain containing 1
chr6_-_39290316 0.96 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16
potassium channel, subfamily K, member 16
chr10_+_124030819 0.96 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr2_-_224702257 0.94 ENST00000409375.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr13_+_109248500 0.93 ENST00000356711.2
MYO16
myosin XVI
chr1_-_204135450 0.92 ENST00000272190.8
ENST00000367195.2
REN
renin
chr12_+_6602517 0.91 ENST00000315579.5
ENST00000539714.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr2_-_224702270 0.90 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr1_+_119957554 0.90 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr16_+_11343475 0.90 ENST00000572173.1
RMI2
RecQ mediated genome instability 2
chr6_-_66417107 0.89 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr2_-_224702201 0.89 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr1_-_6526192 0.87 ENST00000377782.3
ENST00000351959.5
ENST00000356876.3
TNFRSF25
tumor necrosis factor receptor superfamily, member 25
chr1_-_22263790 0.87 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr1_-_156571254 0.86 ENST00000438976.2
ENST00000334588.7
ENST00000368232.4
ENST00000415314.2
GPATCH4
G patch domain containing 4
chr17_-_39211463 0.84 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr12_-_33049690 0.84 ENST00000070846.6
ENST00000340811.4
PKP2
plakophilin 2
chr16_-_88851618 0.83 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr6_+_106546808 0.81 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr8_-_131455835 0.81 ENST00000518721.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr10_+_76871353 0.80 ENST00000542569.1
SAMD8
sterile alpha motif domain containing 8
chr5_+_131409476 0.80 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr4_+_169552748 0.80 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr7_+_77469439 0.79 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr14_-_54955721 0.79 ENST00000554908.1
GMFB
glia maturation factor, beta
chr8_-_105601134 0.78 ENST00000276654.5
ENST00000424843.2
LRP12
low density lipoprotein receptor-related protein 12
chr15_-_34628951 0.78 ENST00000397707.2
ENST00000560611.1
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr1_-_6526167 0.78 ENST00000351748.3
ENST00000348333.3
TNFRSF25
tumor necrosis factor receptor superfamily, member 25
chr4_+_2814011 0.77 ENST00000502260.1
ENST00000435136.2
SH3BP2
SH3-domain binding protein 2
chr19_+_2389784 0.77 ENST00000332578.3
TMPRSS9
transmembrane protease, serine 9
chr11_+_62186498 0.77 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr18_+_29077990 0.77 ENST00000261590.8
DSG2
desmoglein 2
chr10_+_76871454 0.76 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr19_+_35783037 0.75 ENST00000361922.4
MAG
myelin associated glycoprotein
chr19_-_59084647 0.75 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr4_-_165305086 0.74 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr12_-_95611149 0.73 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr19_+_39421556 0.73 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr1_+_31769836 0.73 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
ZCCHC17
zinc finger, CCHC domain containing 17
chr19_+_35783047 0.73 ENST00000595791.1
ENST00000597035.1
ENST00000537831.2
MAG
myelin associated glycoprotein
chr20_+_56884752 0.72 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr11_-_93474645 0.71 ENST00000532455.1
TAF1D
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr19_+_35783028 0.70 ENST00000600291.1
ENST00000392213.3
MAG
myelin associated glycoprotein
chr2_+_219433588 0.70 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr16_+_15744078 0.70 ENST00000396354.1
ENST00000570727.1
NDE1
nudE neurodevelopment protein 1
chr12_+_71833756 0.70 ENST00000536515.1
ENST00000540815.2
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr3_+_50192537 0.70 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr11_+_65343494 0.70 ENST00000309295.4
ENST00000533237.1
EHBP1L1
EH domain binding protein 1-like 1
chr1_+_107683644 0.68 ENST00000370067.1
NTNG1
netrin G1
chr19_+_48216600 0.68 ENST00000263277.3
ENST00000538399.1
EHD2
EH-domain containing 2
chrX_+_38211777 0.68 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chr3_+_50192499 0.68 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_151762943 0.68 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH
tudor and KH domain containing
chr4_-_69111401 0.67 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr3_+_63428752 0.66 ENST00000295894.5
SYNPR
synaptoporin
chr8_-_145018905 0.66 ENST00000398774.2
PLEC
plectin
chr5_-_147162263 0.65 ENST00000333010.6
ENST00000265272.5
JAKMIP2
janus kinase and microtubule interacting protein 2
chr16_-_28223166 0.65 ENST00000304658.5
XPO6
exportin 6
chr3_+_101504200 0.65 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr3_+_63428982 0.65 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr1_+_86046433 0.65 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr16_-_67693846 0.64 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr11_+_67195917 0.64 ENST00000524934.1
ENST00000539188.1
ENST00000312629.5
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr12_-_122240792 0.64 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr6_-_43496605 0.63 ENST00000455285.2
XPO5
exportin 5
chrX_+_46940254 0.63 ENST00000336169.3
RGN
regucalcin
chr21_-_38639813 0.63 ENST00000309117.6
ENST00000398998.1
DSCR3
Down syndrome critical region gene 3
chr1_+_24645865 0.62 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr19_-_6767516 0.62 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr1_+_24645807 0.61 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr15_+_81475047 0.61 ENST00000559388.1
IL16
interleukin 16
chr5_-_147162078 0.61 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr1_+_24646002 0.61 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr19_+_47104493 0.60 ENST00000291295.9
ENST00000597743.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr14_-_67859422 0.60 ENST00000556532.1
PLEK2
pleckstrin 2
chr14_-_24610779 0.59 ENST00000560403.1
ENST00000419198.2
ENST00000216799.4
EMC9
ER membrane protein complex subunit 9
chr2_+_17721920 0.59 ENST00000295156.4
VSNL1
visinin-like 1
chr2_-_130939115 0.58 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
SMPD4
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr7_+_139529040 0.57 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr16_+_31119615 0.57 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
BCKDK
branched chain ketoacid dehydrogenase kinase
chr8_+_38758737 0.57 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr20_+_42984330 0.57 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr16_+_30075463 0.57 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr17_+_7211280 0.56 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A
eukaryotic translation initiation factor 5A
chr16_-_28222797 0.56 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr7_-_22539771 0.56 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr12_+_56732658 0.55 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr9_-_114937676 0.55 ENST00000374270.3
SUSD1
sushi domain containing 1
chr5_-_16916624 0.54 ENST00000513882.1
MYO10
myosin X
chr11_+_61015594 0.54 ENST00000451616.2
PGA5
pepsinogen 5, group I (pepsinogen A)
chr19_-_53636125 0.53 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
ZNF415
zinc finger protein 415
chr1_-_32169920 0.52 ENST00000373672.3
ENST00000373668.3
COL16A1
collagen, type XVI, alpha 1
chr5_-_159797627 0.52 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr20_-_1373682 0.51 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr1_-_32169761 0.51 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr19_-_42931567 0.51 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr8_+_120428546 0.50 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr15_-_71055769 0.50 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr16_+_81478775 0.50 ENST00000537098.3
CMIP
c-Maf inducing protein
chr4_+_140222609 0.50 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_+_42925270 0.50 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chrX_-_45629661 0.50 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr15_-_65398647 0.49 ENST00000502113.2
UBAP1L
ubiquitin associated protein 1-like
chr7_+_139528952 0.49 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr1_-_27930102 0.49 ENST00000247087.5
ENST00000374011.2
AHDC1
AT hook, DNA binding motif, containing 1
chr12_+_9144626 0.48 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr5_+_149877334 0.48 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_+_14716606 0.48 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
C3orf20
chromosome 3 open reading frame 20
chr20_-_656437 0.48 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr1_+_57320437 0.48 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr17_-_74722672 0.47 ENST00000397625.4
ENST00000445478.2
JMJD6
jumonji domain containing 6
chr1_-_153363452 0.47 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr16_+_30075595 0.47 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr16_-_3149278 0.47 ENST00000575108.1
ENST00000576483.1
ENST00000538082.2
ENST00000576985.1
ZSCAN10
zinc finger and SCAN domain containing 10
chr1_+_155829286 0.47 ENST00000368324.4
SYT11
synaptotagmin XI
chr19_-_6767431 0.47 ENST00000437152.3
ENST00000597687.1
SH2D3A
SH2 domain containing 3A
chr6_+_84563295 0.47 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr7_-_99766191 0.47 ENST00000423751.1
ENST00000360039.4
GAL3ST4
galactose-3-O-sulfotransferase 4
chrX_+_151999511 0.46 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr19_+_4402659 0.45 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr5_-_64064508 0.45 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr3_-_28390415 0.45 ENST00000414162.1
ENST00000420543.2
AZI2
5-azacytidine induced 2
chr8_-_55014336 0.45 ENST00000343231.6
LYPLA1
lysophospholipase I
chr4_+_2813946 0.45 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr9_+_95709733 0.45 ENST00000375482.3
FGD3
FYVE, RhoGEF and PH domain containing 3
chr3_+_148847371 0.44 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr12_+_6494285 0.44 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr9_+_125027127 0.44 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr13_-_33760216 0.44 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_225811747 0.43 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr17_+_15604513 0.43 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr1_+_53068020 0.43 ENST00000361314.4
GPX7
glutathione peroxidase 7
chr6_+_30525051 0.43 ENST00000376557.3
PRR3
proline rich 3
chr2_+_130939235 0.43 ENST00000425361.1
ENST00000457492.1
MZT2B
mitotic spindle organizing protein 2B
chr14_+_23299088 0.42 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr18_-_13726510 0.42 ENST00000322247.3
ENST00000592976.1
ENST00000402563.1
ENST00000591269.1
FAM210A
family with sequence similarity 210, member A
chr7_-_32110451 0.42 ENST00000396191.1
ENST00000396182.2
PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr22_-_22221900 0.42 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0042938 dipeptide transport(GO:0042938)
1.1 3.2 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.8 5.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.7 2.2 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.6 5.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.6 1.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 2.1 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.5 1.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.5 1.5 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.5 1.4 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.4 2.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 2.7 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.3 2.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.3 2.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 1.7 GO:0090131 mesenchyme migration(GO:0090131)
0.3 2.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 0.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 2.2 GO:0015705 iodide transport(GO:0015705)
0.2 0.5 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.2 0.7 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.2 0.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 0.6 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.2 0.6 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.2 0.6 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 1.6 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 1.6 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.0 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 2.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.2 1.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 3.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 0.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 0.8 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.2 0.8 GO:0045918 positive regulation of interleukin-23 production(GO:0032747) negative regulation of cytolysis(GO:0045918)
0.2 0.5 GO:1990927 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 0.8 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.9 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 1.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.9 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 2.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.4 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.4 GO:0060752 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.5 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.8 GO:0010193 response to ozone(GO:0010193)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 1.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.0 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.9 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 2.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 4.6 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 1.8 GO:0090178 regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.6 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.4 GO:0016598 protein arginylation(GO:0016598)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 1.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.3 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.4 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.6 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.6 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 9.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.7 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.3 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.8 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.9 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 1.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.1 GO:0001508 action potential(GO:0001508)
0.1 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.5 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.5 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0043473 pigmentation(GO:0043473)
0.0 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.3 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.9 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.4 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.5 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 1.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 1.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:1903147 negative regulation of mitophagy(GO:1903147)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 1.3 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 1.2 GO:0023056 positive regulation of signal transduction(GO:0009967) positive regulation of signaling(GO:0023056)
0.0 0.7 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 2.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.5 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.7 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 1.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 1.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.4 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.6 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.7 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 1.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.1 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.9 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0098743 cell aggregation(GO:0098743)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0061368 negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 1.3 GO:0048675 axon extension(GO:0048675)
0.0 0.6 GO:0042100 B cell proliferation(GO:0042100)
0.0 1.1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 1.1 GO:0048565 digestive tract development(GO:0048565)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.6 2.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.6 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 2.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.3 3.3 GO:0000796 condensin complex(GO:0000796)
0.3 1.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.3 GO:0070876 SOSS complex(GO:0070876)
0.2 0.7 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.2 1.4 GO:0031262 Ndc80 complex(GO:0031262)
0.2 0.6 GO:0042565 RNA nuclear export complex(GO:0042565)
0.2 5.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 1.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 2.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.3 GO:0097443 sorting endosome(GO:0097443)
0.1 0.7 GO:0071547 piP-body(GO:0071547)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 2.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.0 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 1.9 GO:0031143 pseudopodium(GO:0031143)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.5 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 3.7 GO:0001533 cornified envelope(GO:0001533)
0.1 1.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.5 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 2.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0009986 cell surface(GO:0009986)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 1.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 4.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.4 GO:0005768 endosome(GO:0005768)
0.0 2.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 2.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.6 GO:0002102 podosome(GO:0002102)
0.0 2.3 GO:0005902 microvillus(GO:0005902)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 3.0 GO:0001650 fibrillar center(GO:0001650)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 7.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 2.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.3 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 4.7 GO:0005819 spindle(GO:0005819)
0.0 2.5 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.7 2.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.6 2.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 2.8 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 3.9 GO:0004064 arylesterase activity(GO:0004064)
0.5 2.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 1.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 1.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 1.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 0.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 1.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 0.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.6 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 3.7 GO:0048185 activin binding(GO:0048185)
0.2 1.2 GO:0051373 FATZ binding(GO:0051373)
0.2 5.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 1.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 0.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 0.5 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.2 1.9 GO:0008199 ferric iron binding(GO:0008199)
0.2 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 9.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.9 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.4 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 2.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.2 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 3.0 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 3.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 2.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 3.3 PID AURORA B PATHWAY Aurora B signaling
0.0 2.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 2.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 5.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 2.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.9 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.1 0.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 3.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 2.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping