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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TP53

Z-value: 0.85

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
TP53
ENSG00000141510.11 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg19_v2_chr17_-_7590745_7590856-0.271.5e-01Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51504411 7.96 ENST00000593490.1
KLK8
kallikrein-related peptidase 8
chr10_+_11784360 5.68 ENST00000379215.4
ENST00000420401.1
ECHDC3
enoyl CoA hydratase domain containing 3
chr8_-_10588010 4.22 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chr2_+_95691445 3.82 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
MAL
mal, T-cell differentiation protein
chr2_+_95691417 3.81 ENST00000309988.4
MAL
mal, T-cell differentiation protein
chr7_+_100770328 3.40 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr20_+_33759854 3.27 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr17_+_74372662 2.88 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr17_+_76210267 2.77 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr11_+_706595 2.52 ENST00000531348.1
ENST00000530636.1
EPS8L2
EPS8-like 2
chr17_+_76210367 2.42 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr11_-_2160611 2.36 ENST00000416167.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_+_139847347 2.29 ENST00000371632.3
LCN12
lipocalin 12
chr12_+_22778291 2.23 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chrX_+_99899180 1.99 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr6_-_30712313 1.90 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr10_-_105212059 1.85 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr2_-_26205340 1.71 ENST00000264712.3
KIF3C
kinesin family member 3C
chr8_-_23021533 1.61 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr18_-_28622774 1.60 ENST00000434452.1
DSC3
desmocollin 3
chr8_-_23082580 1.59 ENST00000221132.3
TNFRSF10A
tumor necrosis factor receptor superfamily, member 10a
chr1_-_26197744 1.58 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr9_-_95527079 1.58 ENST00000356884.6
ENST00000375512.3
BICD2
bicaudal D homolog 2 (Drosophila)
chr10_-_105212141 1.58 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr18_-_28622699 1.56 ENST00000360428.4
DSC3
desmocollin 3
chrX_-_106959631 1.54 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr10_-_90751038 1.50 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr8_-_22926526 1.44 ENST00000347739.3
ENST00000542226.1
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr3_+_44379611 1.44 ENST00000383746.3
ENST00000417237.1
TCAIM
T cell activation inhibitor, mitochondrial
chr22_+_42949925 1.43 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
SERHL2
serine hydrolase-like 2
chr1_+_28206150 1.43 ENST00000456990.1
THEMIS2
thymocyte selection associated family member 2
chr3_-_12800751 1.40 ENST00000435218.2
ENST00000435575.1
TMEM40
transmembrane protein 40
chr14_-_75079026 1.40 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr19_+_45174724 1.33 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr19_-_14048804 1.33 ENST00000254320.3
ENST00000586075.1
PODNL1
podocan-like 1
chr1_-_6453426 1.33 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr19_+_45174994 1.31 ENST00000403660.3
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr9_+_116037922 1.28 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr19_+_49458107 1.27 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr11_+_60699222 1.23 ENST00000536409.1
TMEM132A
transmembrane protein 132A
chr8_+_22960426 1.21 ENST00000540813.1
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr19_+_926000 1.21 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr1_-_6453399 1.20 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr7_+_116165754 1.19 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr20_+_42984330 1.19 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chrX_+_152086373 1.17 ENST00000318529.8
ZNF185
zinc finger protein 185 (LIM domain)
chr22_+_38302285 1.08 ENST00000215957.6
MICALL1
MICAL-like 1
chr3_+_14166440 1.08 ENST00000306077.4
TMEM43
transmembrane protein 43
chr16_-_15149917 1.03 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr3_+_44379944 1.02 ENST00000396078.3
ENST00000342649.4
TCAIM
T cell activation inhibitor, mitochondrial
chr1_+_10057274 1.01 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr22_+_37447771 0.99 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr19_+_39687596 0.97 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr16_-_15149828 0.97 ENST00000566419.1
ENST00000568320.1
NTAN1
N-terminal asparagine amidase
chr8_-_22926623 0.97 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr3_+_122785895 0.95 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr2_+_197504278 0.94 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150
coiled-coil domain containing 150
chr17_+_25621102 0.94 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1
WD repeat and SOCS box containing 1
chr1_-_209825674 0.92 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr17_+_80332153 0.91 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr1_-_153588334 0.91 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr5_-_131892501 0.90 ENST00000450655.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr1_-_201438282 0.88 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr12_-_53207842 0.88 ENST00000458244.2
KRT4
keratin 4
chr10_+_47746929 0.87 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr10_+_48255253 0.86 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
ANXA8
AL591684.1
annexin A8
Protein LOC100996760
chr2_-_75788038 0.84 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr11_-_3078616 0.83 ENST00000401769.3
ENST00000278224.9
ENST00000397114.3
ENST00000380525.4
CARS
cysteinyl-tRNA synthetase
chr16_+_15744078 0.80 ENST00000396354.1
ENST00000570727.1
NDE1
nudE neurodevelopment protein 1
chr4_-_10117949 0.76 ENST00000508079.1
WDR1
WD repeat domain 1
chr6_+_36098262 0.76 ENST00000373761.6
ENST00000373766.5
MAPK13
mitogen-activated protein kinase 13
chr6_-_101329157 0.75 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr1_-_110283138 0.75 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr1_+_243419306 0.74 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8
serologically defined colon cancer antigen 8
chr19_-_2456922 0.73 ENST00000582871.1
ENST00000325327.3
LMNB2
lamin B2
chr1_-_202936394 0.72 ENST00000367249.4
CYB5R1
cytochrome b5 reductase 1
chr19_-_42746714 0.72 ENST00000222330.3
GSK3A
glycogen synthase kinase 3 alpha
chr1_-_10532531 0.70 ENST00000377036.2
ENST00000377038.3
DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
chr19_-_8809139 0.69 ENST00000324436.3
ACTL9
actin-like 9
chr13_-_48877795 0.69 ENST00000436963.1
ENST00000433480.2
LINC00441
long intergenic non-protein coding RNA 441
chr19_+_2785458 0.68 ENST00000307741.6
ENST00000585338.1
THOP1
thimet oligopeptidase 1
chr2_+_47168630 0.68 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr4_-_48908805 0.68 ENST00000273860.4
OCIAD2
OCIA domain containing 2
chr4_+_153457404 0.66 ENST00000604157.1
ENST00000594836.1
MIR4453
microRNA 4453
chr8_+_22429205 0.65 ENST00000520207.1
SORBS3
sorbin and SH3 domain containing 3
chr4_-_48908822 0.65 ENST00000508632.1
OCIAD2
OCIA domain containing 2
chr16_-_58231782 0.64 ENST00000565188.1
ENST00000262506.3
CSNK2A2
casein kinase 2, alpha prime polypeptide
chr11_+_119039414 0.64 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr9_+_80912059 0.64 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr15_-_89456630 0.64 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr4_-_48908737 0.62 ENST00000381464.2
OCIAD2
OCIA domain containing 2
chr1_+_13910479 0.61 ENST00000509009.1
PDPN
podoplanin
chr11_-_65626753 0.61 ENST00000526975.1
ENST00000531413.1
CFL1
cofilin 1 (non-muscle)
chr4_-_153457197 0.59 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_+_107168342 0.57 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr12_-_126467906 0.56 ENST00000507313.1
ENST00000545784.1
LINC00939
long intergenic non-protein coding RNA 939
chr11_+_64126614 0.56 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr7_+_63361201 0.56 ENST00000450544.1
RP11-340I6.8
RP11-340I6.8
chr9_+_138606400 0.55 ENST00000486577.2
KCNT1
potassium channel, subfamily T, member 1
chr15_-_89456593 0.55 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8
milk fat globule-EGF factor 8 protein
chrX_+_192989 0.55 ENST00000399012.1
ENST00000430923.2
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr3_-_113465065 0.54 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_-_25747283 0.54 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE
Rh blood group, CcEe antigens
chr1_+_156052354 0.54 ENST00000368301.2
LMNA
lamin A/C
chr20_-_1373606 0.54 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr11_-_64084959 0.53 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr1_-_205744574 0.53 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr7_+_23145884 0.53 ENST00000409689.1
ENST00000410047.1
KLHL7
kelch-like family member 7
chr11_-_3078838 0.51 ENST00000397111.5
CARS
cysteinyl-tRNA synthetase
chr22_+_21336267 0.51 ENST00000215739.8
LZTR1
leucine-zipper-like transcription regulator 1
chr4_-_186347099 0.51 ENST00000505357.1
ENST00000264689.6
UFSP2
UFM1-specific peptidase 2
chr7_-_99766191 0.51 ENST00000423751.1
ENST00000360039.4
GAL3ST4
galactose-3-O-sulfotransferase 4
chr12_+_107168418 0.51 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr1_-_205744205 0.49 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr7_-_72742085 0.49 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr19_+_38865398 0.49 ENST00000585598.1
ENST00000602911.1
ENST00000592561.1
PSMD8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr13_+_38923959 0.49 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr17_-_14140166 0.48 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr18_-_34408802 0.47 ENST00000590842.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr6_+_36097992 0.47 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr11_+_67171391 0.47 ENST00000312390.5
TBC1D10C
TBC1 domain family, member 10C
chr1_+_211432700 0.46 ENST00000452621.2
RCOR3
REST corepressor 3
chr1_+_224544552 0.46 ENST00000465271.1
ENST00000366858.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr16_-_29874211 0.46 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr3_-_184079382 0.44 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
CLCN2
chloride channel, voltage-sensitive 2
chr19_+_35862192 0.44 ENST00000597214.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr4_-_10118348 0.44 ENST00000502702.1
WDR1
WD repeat domain 1
chr19_+_35861831 0.44 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr14_-_50999190 0.44 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr7_+_23145366 0.44 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
KLHL7
kelch-like family member 7
chr12_-_64784471 0.43 ENST00000333722.5
C12orf56
chromosome 12 open reading frame 56
chr1_+_54411715 0.43 ENST00000371370.3
ENST00000371368.1
LRRC42
leucine rich repeat containing 42
chr16_+_2961973 0.42 ENST00000399667.2
ENST00000416288.2
ENST00000570425.1
ENST00000573525.1
FLYWCH1
FLYWCH-type zinc finger 1
chr6_+_4776580 0.41 ENST00000397588.3
CDYL
chromodomain protein, Y-like
chr14_-_50999307 0.41 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_-_47168850 0.40 ENST00000409207.1
MCFD2
multiple coagulation factor deficiency 2
chr19_+_3136115 0.40 ENST00000262958.3
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr1_+_11796126 0.40 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr1_+_116519112 0.40 ENST00000369503.4
SLC22A15
solute carrier family 22, member 15
chr19_+_42746927 0.39 ENST00000378108.1
AC006486.1
AC006486.1
chr17_-_72855989 0.39 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr20_-_1373726 0.39 ENST00000400137.4
FKBP1A
FK506 binding protein 1A, 12kDa
chr11_-_65626797 0.38 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr6_-_101329191 0.38 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr21_+_44313375 0.38 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr1_-_1243252 0.38 ENST00000353662.3
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr1_-_1243392 0.38 ENST00000354700.5
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr20_-_1373682 0.38 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr1_+_114447763 0.37 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr1_+_13910757 0.37 ENST00000376061.4
ENST00000513143.1
PDPN
podoplanin
chr1_+_25598872 0.36 ENST00000328664.4
RHD
Rh blood group, D antigen
chr19_+_42364460 0.36 ENST00000593863.1
RPS19
ribosomal protein S19
chr1_-_113249734 0.36 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr10_-_88854518 0.35 ENST00000277865.4
GLUD1
glutamate dehydrogenase 1
chr9_+_35605274 0.35 ENST00000336395.5
TESK1
testis-specific kinase 1
chr9_-_116037840 0.34 ENST00000374206.3
CDC26
cell division cycle 26
chr11_+_67171358 0.34 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr7_+_72742178 0.33 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr11_+_64002292 0.33 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr5_+_121647924 0.33 ENST00000414317.2
SNCAIP
synuclein, alpha interacting protein
chr11_-_82997013 0.33 ENST00000529073.1
ENST00000529611.1
CCDC90B
coiled-coil domain containing 90B
chr16_-_67997947 0.33 ENST00000537830.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr19_+_42364313 0.33 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr6_+_116692102 0.32 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr12_+_69186125 0.32 ENST00000399333.3
AC124890.1
HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr19_+_35849723 0.32 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr3_-_113464906 0.32 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr10_+_90750493 0.31 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr19_+_56652556 0.31 ENST00000337080.3
ZNF444
zinc finger protein 444
chr1_+_11796177 0.31 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP
angiotensin II receptor-associated protein
chr2_-_242447732 0.30 ENST00000439101.1
ENST00000424537.1
ENST00000401869.1
ENST00000436402.1
STK25
serine/threonine kinase 25
chr15_-_34635314 0.30 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr1_-_243418621 0.30 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr16_-_68000717 0.29 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr2_+_47168313 0.29 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr18_+_34409069 0.29 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
KIAA1328
chr7_+_72742162 0.29 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr1_-_113249678 0.29 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr3_-_58196939 0.29 ENST00000394549.2
ENST00000461914.3
DNASE1L3
deoxyribonuclease I-like 3
chr17_+_73089382 0.29 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr10_-_71993176 0.28 ENST00000373232.3
PPA1
pyrophosphatase (inorganic) 1
chr1_-_2458026 0.28 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr1_-_114447683 0.28 ENST00000256658.4
ENST00000369564.1
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr15_-_64455404 0.28 ENST00000300026.3
PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr19_-_5567842 0.27 ENST00000587632.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr1_-_114447620 0.27 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr22_-_38484922 0.26 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr19_+_3585471 0.26 ENST00000322315.5
GIPC3
GIPC PDZ domain containing family, member 3
chr4_-_10118573 0.26 ENST00000382452.2
ENST00000382451.2
WDR1
WD repeat domain 1
chr19_+_13229126 0.26 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chrX_-_153285395 0.26 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr6_+_24403144 0.26 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
MRS2
MRS2 magnesium transporter
chr12_+_56546223 0.25 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chrX_-_153285251 0.25 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr12_-_6451235 0.25 ENST00000440083.2
ENST00000162749.2
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr3_+_196466710 0.25 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr13_-_102068706 0.25 ENST00000251127.6
NALCN
sodium leak channel, non-selective
chr2_-_241759622 0.25 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr19_+_51293672 0.24 ENST00000270593.1
ENST00000270594.3
ACPT
acid phosphatase, testicular
chr4_-_10118469 0.24 ENST00000499869.2
WDR1
WD repeat domain 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.0 8.0 GO:0031642 negative regulation of myelination(GO:0031642)
1.0 2.9 GO:0046521 sphingoid catabolic process(GO:0046521)
0.6 2.5 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.6 7.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 1.3 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.4 1.7 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.4 1.3 GO:0060057 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.4 1.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.3 3.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.3 0.9 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.3 0.9 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3 0.9 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.3 1.5 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.7 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.2 1.6 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.2 5.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.2 0.9 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.2 2.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 1.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 4.3 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.2 0.7 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2 2.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.7 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 1.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.0 GO:2000769 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.6 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 1.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.1 0.5 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 1.3 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 1.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.5 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 0.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.3 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.5 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 5.1 GO:0001706 endoderm formation(GO:0001706)
0.1 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.9 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.4 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.1 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 3.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:1904172 NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.9 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 1.4 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 4.1 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 1.0 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 2.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0097107 postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.3 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 1.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.6 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 1.8 GO:0048477 oogenesis(GO:0048477)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.3 GO:1902403 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 2.0 GO:0007613 memory(GO:0007613)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.8 GO:0015909 long-chain fatty acid transport(GO:0015909)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 1.7 GO:0042643 actomyosin, actin portion(GO:0042643)
0.3 1.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 1.3 GO:1990425 ryanodine receptor complex(GO:1990425)
0.3 1.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.3 GO:0005638 lamin filament(GO:0005638)
0.1 1.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 3.3 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 1.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 6.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 9.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.8 GO:0045569 TRAIL binding(GO:0045569)
0.5 2.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 7.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 1.3 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.4 1.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 0.9 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.3 2.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 2.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.5 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.2 1.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 0.5 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 1.2 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 1.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 1.3 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.6 GO:0034452 dynactin binding(GO:0034452)
0.1 5.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.0 GO:0019841 retinol binding(GO:0019841)
0.1 2.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 1.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.0 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.6 GO:0043295 glutathione binding(GO:0043295)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 1.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 3.9 GO:0019838 growth factor binding(GO:0019838)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 2.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 4.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.5 GO:0043621 protein self-association(GO:0043621)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 3.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 5.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.7 REACTOME KINESINS Genes involved in Kinesins
0.0 5.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 2.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 3.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling