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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for TP73

Z-value: 0.49

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Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
TP73
ENSG00000078900.10 tumor protein p73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg19_v2_chr1_+_3614591_3614622-0.311.0e-01Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_46703069 0.64 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr8_+_120885949 0.54 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr16_-_20367584 0.51 ENST00000570689.1
UMOD
uromodulin
chr20_-_52790512 0.48 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr1_-_236228417 0.48 ENST00000264187.6
NID1
nidogen 1
chr1_-_236228403 0.47 ENST00000366595.3
NID1
nidogen 1
chr6_-_46703430 0.38 ENST00000537365.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr18_-_28681950 0.37 ENST00000251081.6
DSC2
desmocollin 2
chr22_-_37976082 0.36 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chrX_+_72667090 0.35 ENST00000373514.2
CDX4
caudal type homeobox 4
chr17_-_42452063 0.35 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chrX_+_130192318 0.35 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr1_-_26197744 0.35 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr16_+_8891670 0.35 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2
phosphomannomutase 2
chr2_+_95940220 0.34 ENST00000542147.1
PROM2
prominin 2
chr1_+_26485511 0.34 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr1_+_47137445 0.33 ENST00000569393.1
ENST00000334122.4
ENST00000415500.1
TEX38
testis expressed 38
chr15_-_74043816 0.32 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr20_-_52790055 0.31 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr19_-_19626838 0.31 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr1_+_47137544 0.30 ENST00000564373.1
TEX38
testis expressed 38
chr14_+_105190514 0.29 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr2_+_95940186 0.29 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
PROM2
prominin 2
chr16_+_5008290 0.29 ENST00000251170.7
SEC14L5
SEC14-like 5 (S. cerevisiae)
chrX_+_130192216 0.27 ENST00000276211.5
ARHGAP36
Rho GTPase activating protein 36
chr1_+_110082487 0.27 ENST00000527748.1
GPR61
G protein-coupled receptor 61
chr19_+_41620335 0.26 ENST00000331105.2
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr14_+_103566481 0.26 ENST00000380069.3
EXOC3L4
exocyst complex component 3-like 4
chr14_+_103566665 0.25 ENST00000559116.1
EXOC3L4
exocyst complex component 3-like 4
chr1_-_203055129 0.25 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr8_-_145016692 0.25 ENST00000357649.2
PLEC
plectin
chr5_+_38258511 0.25 ENST00000354891.3
ENST00000322350.5
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr17_-_40835076 0.24 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr11_+_65154070 0.24 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr11_+_75479850 0.24 ENST00000376262.3
ENST00000604733.1
DGAT2
diacylglycerol O-acyltransferase 2
chr17_+_78388959 0.23 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV
endonuclease V
chr10_-_105212059 0.22 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr1_-_160832642 0.22 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr2_+_114163945 0.22 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr10_-_105212141 0.21 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr14_-_25519095 0.21 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr17_-_79818354 0.20 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chrX_-_131228291 0.20 ENST00000370879.1
FRMD7
FERM domain containing 7
chr15_+_74466744 0.20 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr17_+_37356528 0.19 ENST00000225430.4
RPL19
ribosomal protein L19
chr2_-_26864228 0.19 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr9_+_36169380 0.19 ENST00000335119.2
CCIN
calicin
chr17_+_37356586 0.19 ENST00000579260.1
ENST00000582193.1
RPL19
ribosomal protein L19
chr11_+_60197040 0.18 ENST00000300190.2
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr3_-_100120223 0.18 ENST00000284320.5
TOMM70A
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr14_-_25519317 0.18 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr1_+_162467595 0.17 ENST00000538489.1
ENST00000489294.1
UHMK1
U2AF homology motif (UHM) kinase 1
chr6_+_31515337 0.17 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr20_-_62203808 0.17 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr6_-_112194484 0.17 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr2_+_220283091 0.17 ENST00000373960.3
DES
desmin
chr17_+_37356555 0.17 ENST00000579374.1
RPL19
ribosomal protein L19
chr2_+_128293323 0.17 ENST00000389524.4
ENST00000428314.1
MYO7B
myosin VIIB
chr17_+_43318434 0.16 ENST00000587489.1
FMNL1
formin-like 1
chr13_-_48877795 0.16 ENST00000436963.1
ENST00000433480.2
LINC00441
long intergenic non-protein coding RNA 441
chr7_-_27213893 0.16 ENST00000283921.4
HOXA10
homeobox A10
chr6_-_72130472 0.16 ENST00000426635.2
LINC00472
long intergenic non-protein coding RNA 472
chr19_-_35981358 0.16 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr18_+_77623668 0.16 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr5_-_135528822 0.15 ENST00000607574.1
AC009014.3
AC009014.3
chr1_+_156785425 0.14 ENST00000392302.2
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr17_-_39023462 0.14 ENST00000251643.4
KRT12
keratin 12
chr17_+_54230819 0.14 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr17_+_72427477 0.14 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_+_136676851 0.14 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr19_+_19627026 0.14 ENST00000608404.1
ENST00000555938.1
ENST00000503283.1
ENST00000512771.3
ENST00000428459.2
YJEFN3
CTC-260F20.3
NDUFA13
YjeF N-terminal domain containing 3
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr11_-_65686496 0.14 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr16_-_8891481 0.14 ENST00000333050.6
TMEM186
transmembrane protein 186
chr19_+_49622646 0.13 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr22_+_39966758 0.13 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr12_+_113495492 0.13 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr9_-_132383055 0.12 ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr1_-_220219775 0.12 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr10_-_105238997 0.12 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chr1_-_220220000 0.12 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr17_+_73750699 0.12 ENST00000584939.1
ITGB4
integrin, beta 4
chrX_-_138724677 0.11 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr16_-_2581409 0.11 ENST00000567119.1
ENST00000565480.1
ENST00000382350.1
CEMP1
cementum protein 1
chr10_+_47746929 0.11 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr3_+_136676707 0.11 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr17_-_47492236 0.11 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr2_-_230135937 0.10 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
PID1
phosphotyrosine interaction domain containing 1
chr3_+_42201653 0.10 ENST00000341421.3
ENST00000396175.1
TRAK1
trafficking protein, kinesin binding 1
chr18_-_4455260 0.10 ENST00000581527.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr9_+_6757634 0.10 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr8_+_37654424 0.10 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr15_+_75498739 0.10 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr15_+_41136216 0.09 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr17_-_42200996 0.09 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr3_+_48481658 0.09 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr4_+_6717842 0.08 ENST00000320776.3
BLOC1S4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr19_+_17326521 0.08 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr15_+_41136586 0.08 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr17_-_2614927 0.08 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr6_+_155537771 0.08 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr10_-_97200772 0.07 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr16_-_68000717 0.07 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr11_+_65686952 0.07 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr11_-_17035943 0.07 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr6_-_122792919 0.07 ENST00000339697.4
SERINC1
serine incorporator 1
chr17_-_80059726 0.07 ENST00000583053.1
CCDC57
coiled-coil domain containing 57
chr1_-_52344471 0.06 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chrX_-_138724994 0.06 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr8_+_37654693 0.06 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr14_+_72399833 0.06 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr10_+_70661014 0.06 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr17_-_47492164 0.05 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
PHB
prohibitin
chr3_-_50340996 0.05 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr5_-_156593273 0.05 ENST00000302938.4
FAM71B
family with sequence similarity 71, member B
chr16_+_21312170 0.05 ENST00000338573.5
ENST00000561968.1
CRYM-AS1
CRYM antisense RNA 1
chr11_+_65687158 0.05 ENST00000532933.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr22_-_20255212 0.05 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr4_-_76598544 0.05 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr7_-_2883928 0.05 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr11_+_63449045 0.05 ENST00000354497.4
RTN3
reticulon 3
chr8_-_70745575 0.04 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr14_+_22217447 0.04 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr17_+_4835580 0.04 ENST00000329125.5
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr1_-_235324530 0.04 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RBM34
RNA binding motif protein 34
chr12_+_44152740 0.03 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr14_+_22554680 0.03 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chr19_-_39226045 0.03 ENST00000597987.1
ENST00000595177.1
CAPN12
calpain 12
chr5_+_78532003 0.03 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr2_-_27357479 0.03 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr11_-_75062829 0.02 ENST00000393505.4
ARRB1
arrestin, beta 1
chr10_-_91295304 0.01 ENST00000341233.4
ENST00000371790.4
SLC16A12
solute carrier family 16, member 12
chr3_-_48936272 0.01 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr5_+_139027877 0.01 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr6_+_35995552 0.01 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr12_-_91573249 0.01 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr6_+_35995531 0.01 ENST00000229794.4
MAPK14
mitogen-activated protein kinase 14
chr17_+_7792101 0.00 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr1_-_214724566 0.00 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.2 1.0 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.2 0.6 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.5 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.2 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.2 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.9 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:1903862 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.2 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:2001170 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0097421 liver regeneration(GO:0097421)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0044393 microspike(GO:0044393)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 1.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.0 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins