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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for UUGGCAA

Z-value: 0.53

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miRNA associated with seed UUGGCAA

NamemiRBASE accession
hsa-miR-182-5p
MIMAT0000259

Activity profile of UUGGCAA motif

Sorted Z-values of UUGGCAA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_160473996 2.01 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr7_-_158380465 1.86 ENST00000389413.3
ENST00000409483.1
PTPRN2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr13_+_24734844 1.78 ENST00000382108.3
SPATA13
spermatogenesis associated 13
chr6_+_135502466 1.59 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr14_+_75536280 1.36 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr6_-_10838710 1.31 ENST00000313243.2
MAK
male germ cell-associated kinase
chr5_-_16509101 1.31 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr2_-_220110187 1.27 ENST00000295759.7
ENST00000392089.2
GLB1L
galactosidase, beta 1-like
chr2_+_85981008 1.24 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr19_+_32896697 1.23 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr5_+_50678921 1.20 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr3_+_238273 1.18 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr1_+_3607228 1.17 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73
tumor protein p73
chr15_-_49255632 1.11 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_+_20512568 1.10 ENST00000375099.3
UBXN10
UBX domain protein 10
chr12_-_56652111 1.10 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr3_+_69812877 1.09 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr17_-_1532106 1.09 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chrX_+_16964794 1.06 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr10_-_46167722 1.00 ENST00000374366.3
ENST00000344646.5
ZFAND4
zinc finger, AN1-type domain 4
chr7_+_30174426 0.98 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_+_97481974 0.96 ENST00000377060.3
ENST00000305510.3
CNNM3
cyclin M3
chr10_-_62704005 0.95 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr19_-_14316980 0.93 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr1_-_217262969 0.91 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr1_+_57110972 0.89 ENST00000371244.4
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr6_-_90121938 0.88 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr6_+_138483058 0.85 ENST00000251691.4
KIAA1244
KIAA1244
chr20_-_21494654 0.84 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr3_-_9994021 0.83 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr11_+_46299199 0.82 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr14_-_90085458 0.81 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr2_-_213403565 0.80 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr8_+_101170257 0.80 ENST00000251809.3
SPAG1
sperm associated antigen 1
chr6_+_36164487 0.77 ENST00000357641.6
BRPF3
bromodomain and PHD finger containing, 3
chr3_+_179370517 0.77 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr17_+_72322346 0.77 ENST00000551294.1
ENST00000389916.4
KIF19
kinesin family member 19
chr6_-_79787902 0.73 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr4_-_83483395 0.72 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr10_+_72164135 0.71 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr4_+_108745711 0.71 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr8_+_28351707 0.70 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr6_+_1312675 0.69 ENST00000296839.2
FOXQ1
forkhead box Q1
chr1_+_180601139 0.69 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr8_+_120885949 0.68 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr18_-_54305658 0.68 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chr11_+_111807863 0.68 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr20_+_42086525 0.66 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr6_-_36842784 0.65 ENST00000373699.5
PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chr5_-_179499086 0.64 ENST00000261947.4
RNF130
ring finger protein 130
chr3_+_61547585 0.64 ENST00000295874.10
ENST00000474889.1
PTPRG
protein tyrosine phosphatase, receptor type, G
chr6_-_99395787 0.64 ENST00000369244.2
ENST00000229971.1
FBXL4
F-box and leucine-rich repeat protein 4
chr21_-_34852304 0.64 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr12_-_94853716 0.63 ENST00000339839.5
ENST00000397809.5
ENST00000547575.1
CCDC41
coiled-coil domain containing 41
chr9_-_139922631 0.62 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr2_-_152955537 0.61 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr3_+_181429704 0.61 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr1_-_86043921 0.60 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_+_14444063 0.59 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr16_+_50775948 0.58 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr3_+_187930719 0.58 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr9_-_80646374 0.58 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr3_-_114790179 0.57 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_133968529 0.57 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr2_-_86564776 0.56 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chrX_+_72783026 0.56 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr7_+_94139105 0.55 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr19_-_33555780 0.55 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr3_-_161090660 0.55 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr14_+_74111578 0.55 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr9_+_976964 0.55 ENST00000190165.2
DMRT3
doublesex and mab-3 related transcription factor 3
chr1_+_109656579 0.55 ENST00000526264.1
ENST00000369939.3
KIAA1324
KIAA1324
chr1_-_234614849 0.55 ENST00000040877.1
TARBP1
TAR (HIV-1) RNA binding protein 1
chr6_+_80341000 0.54 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr7_+_17338239 0.54 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr10_+_104613980 0.53 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32
chrX_+_9431324 0.53 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr8_-_130951940 0.53 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B
family with sequence similarity 49, member B
chr14_-_39901618 0.52 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr8_+_123793633 0.52 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr14_+_57735614 0.52 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr14_-_53619816 0.51 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1
DDHD domain containing 1
chr21_-_40685477 0.51 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr5_+_153825510 0.51 ENST00000297109.6
SAP30L
SAP30-like
chr6_-_80247105 0.50 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr16_+_77822427 0.50 ENST00000302536.2
VAT1L
vesicle amine transport 1-like
chr12_+_110906169 0.50 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr10_-_61469837 0.49 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr17_+_4981535 0.48 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr2_+_45878790 0.48 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr3_-_46037299 0.48 ENST00000296137.2
FYCO1
FYVE and coiled-coil domain containing 1
chr9_+_71320596 0.48 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr11_-_64612041 0.47 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chrX_+_70752917 0.46 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_+_46524537 0.46 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr14_+_56046914 0.45 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr4_+_184826418 0.45 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chrX_+_17393543 0.45 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_+_71998506 0.43 ENST00000370435.4
OGFRL1
opioid growth factor receptor-like 1
chr7_-_130080977 0.43 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr17_-_27621125 0.43 ENST00000579665.1
ENST00000225388.4
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr1_+_101361626 0.43 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr10_-_98480243 0.43 ENST00000339364.5
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr22_-_44894178 0.43 ENST00000341255.3
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr15_-_83316254 0.42 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr4_+_41362796 0.42 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr7_+_107110488 0.42 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr10_-_116286656 0.41 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
ABLIM1
actin binding LIM protein 1
chr10_-_62149433 0.41 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_13390270 0.40 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr4_-_88141755 0.39 ENST00000273963.5
KLHL8
kelch-like family member 8
chr7_+_94285637 0.39 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr3_-_133614597 0.39 ENST00000285208.4
ENST00000460865.3
RAB6B
RAB6B, member RAS oncogene family
chr1_+_9294822 0.39 ENST00000377403.2
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr14_+_105331596 0.38 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B
centrosomal protein 170B
chr20_-_50384864 0.38 ENST00000311637.5
ENST00000402822.1
ATP9A
ATPase, class II, type 9A
chrX_-_117250740 0.38 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
KLHL13
kelch-like family member 13
chr2_+_162272605 0.38 ENST00000389554.3
TBR1
T-box, brain, 1
chr3_+_155588300 0.38 ENST00000496455.2
GMPS
guanine monphosphate synthase
chr5_-_90679145 0.38 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr8_+_61429416 0.37 ENST00000262646.7
ENST00000531289.1
RAB2A
RAB2A, member RAS oncogene family
chr13_+_98794810 0.37 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr9_+_104161123 0.36 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189
zinc finger protein 189
chr7_-_112727774 0.36 ENST00000297146.3
ENST00000501255.2
GPR85
G protein-coupled receptor 85
chr13_+_108870714 0.36 ENST00000375898.3
ABHD13
abhydrolase domain containing 13
chr16_-_87525651 0.36 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr6_+_56954867 0.36 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr20_+_33292068 0.36 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr1_+_231664390 0.35 ENST00000366639.4
ENST00000413309.2
TSNAX
translin-associated factor X
chr1_+_113615794 0.35 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr1_-_16678914 0.35 ENST00000375592.3
FBXO42
F-box protein 42
chr22_-_39548627 0.35 ENST00000216133.5
CBX7
chromobox homolog 7
chr20_-_50419055 0.34 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr1_+_15943995 0.34 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr7_+_87257701 0.33 ENST00000338056.3
ENST00000493037.1
RUNDC3B
RUN domain containing 3B
chr5_-_9546180 0.33 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr6_+_17600576 0.33 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr6_+_69345166 0.33 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr8_-_103876965 0.32 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr13_+_115079949 0.32 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr1_-_177133818 0.31 ENST00000424564.2
ENST00000361833.2
ASTN1
astrotactin 1
chr1_-_154934200 0.31 ENST00000368457.2
PYGO2
pygopus family PHD finger 2
chr9_+_79074068 0.31 ENST00000444201.2
ENST00000376730.4
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_-_95225768 0.31 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr7_-_25164969 0.31 ENST00000305786.2
CYCS
cytochrome c, somatic
chr17_-_33760164 0.30 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12
schlafen family member 12
chr1_-_202858227 0.30 ENST00000367262.3
RABIF
RAB interacting factor
chr10_-_52383644 0.30 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr3_-_134093395 0.29 ENST00000249883.5
AMOTL2
angiomotin like 2
chr10_+_102295616 0.29 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr13_+_100634004 0.29 ENST00000376335.3
ZIC2
Zic family member 2
chr12_-_104234966 0.29 ENST00000392876.3
NT5DC3
5'-nucleotidase domain containing 3
chr12_-_42538657 0.29 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr9_-_125675576 0.29 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr11_+_123396528 0.28 ENST00000322282.7
ENST00000529750.1
GRAMD1B
GRAM domain containing 1B
chr4_+_146402925 0.28 ENST00000302085.4
SMAD1
SMAD family member 1
chr19_-_6279932 0.27 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr11_-_73309228 0.27 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr10_-_73533255 0.27 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr22_-_36903101 0.27 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr11_-_79151695 0.27 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr17_+_61699766 0.27 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr10_+_111767720 0.27 ENST00000356080.4
ENST00000277900.8
ADD3
adducin 3 (gamma)
chr14_+_71374122 0.27 ENST00000304743.2
ENST00000238570.5
PCNX
pecanex homolog (Drosophila)
chr12_+_69864129 0.27 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr14_+_105781048 0.26 ENST00000458164.2
ENST00000447393.1
PACS2
phosphofurin acidic cluster sorting protein 2
chr2_+_208394616 0.26 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr12_+_104682496 0.26 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr19_-_33793430 0.26 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr12_-_56727487 0.26 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr6_-_109703663 0.26 ENST00000368961.5
CD164
CD164 molecule, sialomucin
chr4_-_16228120 0.25 ENST00000405303.2
TAPT1
transmembrane anterior posterior transformation 1
chr9_-_79520989 0.25 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr2_+_46769798 0.25 ENST00000238738.4
RHOQ
ras homolog family member Q
chr9_+_91003271 0.25 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr5_+_71403061 0.25 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr11_-_46142948 0.25 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr3_-_88108192 0.24 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr20_+_30865429 0.24 ENST00000375712.3
KIF3B
kinesin family member 3B
chr2_+_86947296 0.24 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr12_+_113229737 0.24 ENST00000551052.1
ENST00000415485.3
RPH3A
rabphilin 3A homolog (mouse)
chr1_-_93257951 0.24 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5
ecotropic viral integration site 5
chr1_-_231004220 0.24 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr11_+_7597639 0.24 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_+_114055052 0.23 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr6_-_86352642 0.23 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_-_115375107 0.23 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr5_-_114880533 0.23 ENST00000274457.3
FEM1C
fem-1 homolog c (C. elegans)
chr7_+_142985308 0.23 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr11_-_94964354 0.23 ENST00000536441.1
SESN3
sestrin 3
chr7_-_47621736 0.22 ENST00000311160.9
TNS3
tensin 3
chr2_+_32288725 0.22 ENST00000315285.3
SPAST
spastin
chr4_+_95679072 0.22 ENST00000515059.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_157108130 0.22 ENST00000368192.4
ETV3
ets variant 3
chr9_+_129677039 0.22 ENST00000259351.5
ENST00000424082.2
ENST00000394022.3
ENST00000394011.3
ENST00000319107.4
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr12_-_58240470 0.22 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr2_-_38303218 0.22 ENST00000407341.1
ENST00000260630.3
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr8_-_93978357 0.22 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr5_+_67511524 0.22 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr16_+_71879861 0.22 ENST00000427980.2
ENST00000568581.1
ATXN1L
IST1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of UUGGCAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4 1.2 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.3 0.8 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 0.8 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.3 0.8 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.7 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2 0.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 0.5 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.2 1.2 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.3 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.4 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.5 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.6 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.8 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.4 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.6 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.5 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.5 GO:0021764 amygdala development(GO:0021764)
0.1 0.9 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.1 GO:0061010 gall bladder development(GO:0061010)
0.1 0.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.2 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.2 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.1 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.1 GO:0060066 oviduct development(GO:0060066)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.2 GO:0060044 negative regulation of JUN kinase activity(GO:0043508) negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.9 GO:0035404 histone-serine phosphorylation(GO:0035404) fatty acid homeostasis(GO:0055089)
0.0 1.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.6 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.4 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 1.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 1.2 GO:0035640 exploration behavior(GO:0035640)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.0 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.4 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 1.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983) response to dithiothreitol(GO:0072720)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 2.1 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 1.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.2 GO:0098760 interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.3 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.7 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.4 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.8 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0043586 tongue development(GO:0043586)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.9 GO:0097542 ciliary tip(GO:0097542)
0.1 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.0 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.3 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.5 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.5 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 1.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.4 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 1.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.5 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 2.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.3 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 2.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0008523 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.0 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling