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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for VDR

Z-value: 0.87

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Transcription factors associated with VDR

Gene Symbol Gene ID Gene Info
VDR
ENSG00000111424.6 vitamin D receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VDRhg19_v2_chr12_-_48298785_482988280.412.3e-02Click!

Activity profile of VDR motif

Sorted Z-values of VDR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102928009 4.28 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr16_-_2770216 2.69 ENST00000302641.3
PRSS27
protease, serine 27
chr2_-_235405168 2.67 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr5_-_39270725 2.60 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr10_-_5541525 2.29 ENST00000380332.3
CALML5
calmodulin-like 5
chr17_+_2699697 1.88 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr11_-_65667997 1.86 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr2_+_210517895 1.81 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr20_+_30327063 1.79 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr20_-_52790512 1.78 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr12_-_133050726 1.74 ENST00000595994.1
MUC8
mucin 8
chr9_+_139839711 1.69 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr11_-_28129656 1.66 ENST00000263181.6
KIF18A
kinesin family member 18A
chr11_-_65667884 1.59 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr1_+_17559776 1.58 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr17_-_36347835 1.53 ENST00000519532.1
TBC1D3
TBC1 domain family, member 3
chr17_-_34807272 1.53 ENST00000535592.1
ENST00000394453.1
TBC1D3G
TBC1 domain family, member 3G
chr7_+_155090271 1.52 ENST00000476756.1
INSIG1
insulin induced gene 1
chr17_-_36348610 1.52 ENST00000339023.4
ENST00000354664.4
TBC1D3
TBC1 domain family, member 3
chr17_-_34808047 1.52 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1D3G
TBC1D3H
TBC1 domain family, member 3G
TBC1 domain family, member 3H
chr11_-_61582579 1.51 ENST00000539419.1
ENST00000545245.1
ENST00000545405.1
ENST00000542506.1
FADS1
fatty acid desaturase 1
chr17_-_34756219 1.51 ENST00000451448.2
ENST00000394359.3
TBC1D3C
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chr7_+_143701022 1.43 ENST00000408922.2
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr17_+_36284791 1.41 ENST00000505415.1
TBC1D3F
TBC1 domain family, member 3F
chr14_+_94640633 1.35 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr1_-_75198940 1.25 ENST00000417775.1
CRYZ
crystallin, zeta (quinone reductase)
chr16_+_2479390 1.23 ENST00000397066.4
CCNF
cyclin F
chr12_+_110011571 1.20 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr9_+_131644781 1.17 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr5_-_147211190 1.15 ENST00000510027.2
SPINK1
serine peptidase inhibitor, Kazal type 1
chr9_+_139839686 1.15 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr8_+_26371763 1.09 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chr1_-_221915418 1.09 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr19_+_38826415 1.08 ENST00000410018.1
ENST00000409235.3
CATSPERG
catsper channel auxiliary subunit gamma
chr5_-_147211226 1.07 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr8_-_145028013 1.06 ENST00000354958.2
PLEC
plectin
chr4_+_142557771 1.04 ENST00000514653.1
IL15
interleukin 15
chr10_+_54074033 1.00 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr8_+_95653427 1.00 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chr10_+_80008505 0.99 ENST00000434974.1
ENST00000423770.1
ENST00000432742.1
LINC00856
long intergenic non-protein coding RNA 856
chr11_-_64527425 0.98 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr17_-_34591208 0.95 ENST00000336331.5
TBC1D3C
TBC1 domain family, member 3C
chr4_-_103266626 0.93 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr8_-_22926526 0.92 ENST00000347739.3
ENST00000542226.1
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr2_-_85625857 0.92 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chrX_-_65253506 0.92 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr19_-_16045665 0.92 ENST00000248041.8
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr17_-_43487741 0.87 ENST00000455881.1
ARHGAP27
Rho GTPase activating protein 27
chr19_-_16045619 0.87 ENST00000402119.4
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr12_+_57857475 0.85 ENST00000528467.1
GLI1
GLI family zinc finger 1
chr1_+_153232160 0.85 ENST00000368742.3
LOR
loricrin
chr8_+_95653302 0.85 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr11_+_73882144 0.83 ENST00000328257.8
PPME1
protein phosphatase methylesterase 1
chr8_+_95653373 0.82 ENST00000358397.5
ESRP1
epithelial splicing regulatory protein 1
chr13_+_114321463 0.82 ENST00000335678.6
GRK1
G protein-coupled receptor kinase 1
chr1_-_38218577 0.80 ENST00000540011.1
EPHA10
EPH receptor A10
chr11_+_73882311 0.76 ENST00000398427.4
ENST00000544401.1
PPME1
protein phosphatase methylesterase 1
chr10_-_33623826 0.75 ENST00000374867.2
NRP1
neuropilin 1
chr19_-_35992780 0.75 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr12_-_96390063 0.74 ENST00000541929.1
HAL
histidine ammonia-lyase
chr11_+_57365150 0.73 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr10_-_76995769 0.73 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr11_+_6624970 0.72 ENST00000420936.2
ENST00000528995.1
ILK
integrin-linked kinase
chr8_-_13134045 0.71 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr1_-_6550625 0.69 ENST00000377725.1
ENST00000340850.5
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr12_+_10658489 0.69 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr10_-_33623564 0.69 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr10_-_33624002 0.69 ENST00000432372.2
NRP1
neuropilin 1
chr1_+_3816936 0.68 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
RP13-15E13.1
long intergenic non-protein coding RNA 1134
chr7_+_65552756 0.67 ENST00000450043.1
AC068533.7
AC068533.7
chr21_-_47575481 0.67 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD
formimidoyltransferase cyclodeaminase
chr17_-_64225508 0.67 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr16_-_67217844 0.66 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr4_-_103266219 0.65 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_+_6625046 0.65 ENST00000396751.2
ILK
integrin-linked kinase
chr6_+_24775153 0.65 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr11_+_6624955 0.65 ENST00000299421.4
ENST00000537806.1
ILK
integrin-linked kinase
chr10_+_5454505 0.64 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr6_+_30525051 0.64 ENST00000376557.3
PRR3
proline rich 3
chr11_+_28129795 0.64 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr19_+_1407517 0.63 ENST00000336761.6
ENST00000233078.4
DAZAP1
DAZ associated protein 1
chr3_+_111578131 0.63 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_+_79439405 0.63 ENST00000552744.1
SYT1
synaptotagmin I
chr1_-_67519782 0.62 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr8_-_22926623 0.62 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr19_-_19932501 0.62 ENST00000540806.2
ENST00000590766.1
ENST00000587452.1
ENST00000545006.1
ENST00000590319.1
ENST00000587461.1
ENST00000450683.2
ENST00000443905.2
ENST00000590274.1
ZNF506
CTC-559E9.4
zinc finger protein 506
CTC-559E9.4
chr17_-_43487780 0.61 ENST00000532038.1
ENST00000528677.1
ARHGAP27
Rho GTPase activating protein 27
chr17_-_46716647 0.60 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr6_+_30524663 0.60 ENST00000376560.3
PRR3
proline rich 3
chr8_+_10383039 0.59 ENST00000328655.3
ENST00000522210.1
PRSS55
protease, serine, 55
chr1_-_19426149 0.59 ENST00000429347.2
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr9_-_115095123 0.58 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr16_+_31119615 0.58 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
BCKDK
branched chain ketoacid dehydrogenase kinase
chr6_-_30524951 0.57 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr7_-_36764142 0.54 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chrX_+_153813407 0.54 ENST00000443287.2
ENST00000333128.3
CTAG1A
cancer/testis antigen 1A
chr17_+_78388959 0.52 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV
endonuclease V
chr9_+_71789133 0.52 ENST00000348208.4
ENST00000265384.7
TJP2
tight junction protein 2
chrX_+_43515467 0.52 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr7_-_22539771 0.51 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr12_+_57610562 0.51 ENST00000349394.5
NXPH4
neurexophilin 4
chr9_+_138391805 0.50 ENST00000371785.1
MRPS2
mitochondrial ribosomal protein S2
chr2_+_198557830 0.50 ENST00000409845.1
AC011997.1
Uncharacterized protein
chr19_+_50270219 0.49 ENST00000354293.5
ENST00000359032.5
AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr15_-_99057551 0.46 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr12_-_114404111 0.45 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RBM19
RNA binding motif protein 19
chrX_-_153881842 0.45 ENST00000369585.3
ENST00000247306.4
CTAG2
cancer/testis antigen 2
chr2_+_220363579 0.45 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA
GDP-mannose pyrophosphorylase A
chr4_+_158142750 0.45 ENST00000505888.1
ENST00000449365.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr9_+_130213774 0.45 ENST00000373324.4
ENST00000323301.4
LRSAM1
leucine rich repeat and sterile alpha motif containing 1
chr14_+_22984601 0.45 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr2_+_87769459 0.45 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_+_54157480 0.44 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr3_-_122283100 0.43 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr5_-_82969405 0.43 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr16_-_2260834 0.43 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr13_-_33859819 0.43 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_+_108905095 0.43 ENST00000251481.6
ENST00000326853.5
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr11_-_104817919 0.43 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr20_+_55904815 0.41 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11
SPO11 meiotic protein covalently bound to DSB
chr14_-_75330537 0.41 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr14_+_105212297 0.41 ENST00000556623.1
ENST00000555674.1
ADSSL1
adenylosuccinate synthase like 1
chr14_-_24806588 0.40 ENST00000555591.1
ENST00000554569.1
RP11-934B9.3
RIPK3
Uncharacterized protein
receptor-interacting serine-threonine kinase 3
chr12_+_48876275 0.40 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr15_+_83776324 0.40 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1
transmembrane 6 superfamily member 1
chr4_-_164534657 0.39 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_36764004 0.39 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr6_+_167704838 0.39 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr13_-_38172863 0.39 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr1_+_26348259 0.38 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr17_+_53828333 0.38 ENST00000268896.5
PCTP
phosphatidylcholine transfer protein
chr11_-_111794446 0.36 ENST00000527950.1
CRYAB
crystallin, alpha B
chr17_+_79213039 0.36 ENST00000431388.2
C17orf89
chromosome 17 open reading frame 89
chr10_-_18940501 0.35 ENST00000377304.4
NSUN6
NOP2/Sun domain family, member 6
chr15_+_41851211 0.35 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr7_+_155089486 0.35 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1
insulin induced gene 1
chr20_+_30028322 0.35 ENST00000376309.3
DEFB123
defensin, beta 123
chr19_-_40331345 0.35 ENST00000597224.1
FBL
fibrillarin
chr17_+_53828381 0.34 ENST00000576183.1
PCTP
phosphatidylcholine transfer protein
chr1_+_47137445 0.34 ENST00000569393.1
ENST00000334122.4
ENST00000415500.1
TEX38
testis expressed 38
chr13_+_57721622 0.34 ENST00000377930.1
PRR20B
proline rich 20B
chr7_-_151433393 0.34 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr22_-_17680472 0.34 ENST00000330232.4
CECR1
cat eye syndrome chromosome region, candidate 1
chr1_+_47137544 0.33 ENST00000564373.1
TEX38
testis expressed 38
chr20_+_58630972 0.33 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr7_-_151433342 0.33 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr11_+_18433840 0.33 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr14_-_20801427 0.33 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr6_+_167704798 0.33 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr15_+_75940218 0.33 ENST00000308527.5
SNX33
sorting nexin 33
chr2_+_11752379 0.32 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr14_-_106781017 0.32 ENST00000390612.2
IGHV4-28
immunoglobulin heavy variable 4-28
chr12_-_71512027 0.32 ENST00000549357.1
CTD-2021H9.3
Uncharacterized protein
chr1_-_205325850 0.31 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr18_-_44544607 0.30 ENST00000591973.2
TCEB3CL2
transcription elongation factor B polypeptide 3C-like 2
chr2_-_202483867 0.30 ENST00000439802.1
ENST00000286195.3
ENST00000439140.1
ENST00000450242.1
ALS2CR11
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
chr12_-_96390108 0.30 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr16_+_1128781 0.29 ENST00000293897.4
ENST00000562758.1
SSTR5
somatostatin receptor 5
chr16_-_31106048 0.29 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr11_+_124609823 0.29 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr16_-_31106211 0.29 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr1_-_200992827 0.28 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr8_+_9046503 0.28 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr12_-_109221160 0.28 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr18_-_44556449 0.28 ENST00000330682.2
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr2_+_176957619 0.28 ENST00000392539.3
HOXD13
homeobox D13
chr19_-_49122384 0.28 ENST00000550973.1
ENST00000550645.1
ENST00000549273.1
ENST00000552588.1
RPL18
ribosomal protein L18
chr9_+_131038425 0.27 ENST00000320188.5
ENST00000608796.1
ENST00000419867.2
ENST00000418976.1
SWI5
SWI5 recombination repair homolog (yeast)
chr22_+_50624323 0.27 ENST00000380909.4
ENST00000303434.4
TRABD
TraB domain containing
chr12_-_6579833 0.27 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr1_+_175036966 0.26 ENST00000239462.4
TNN
tenascin N
chr14_-_91884150 0.26 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr2_+_108905325 0.26 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr6_+_46661575 0.26 ENST00000450697.1
TDRD6
tudor domain containing 6
chr6_+_56819895 0.26 ENST00000370748.3
BEND6
BEN domain containing 6
chr10_+_104154229 0.25 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr16_+_640201 0.24 ENST00000563109.1
RAB40C
RAB40C, member RAS oncogene family
chr9_+_125376948 0.24 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr1_+_24069952 0.24 ENST00000609199.1
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr16_-_31105870 0.23 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr12_+_27091426 0.23 ENST00000546072.1
ENST00000327214.5
FGFR1OP2
FGFR1 oncogene partner 2
chr16_-_31228680 0.23 ENST00000302964.3
PYDC1
PYD (pyrin domain) containing 1
chr14_-_54908043 0.23 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr11_-_104840093 0.23 ENST00000417440.2
ENST00000444739.2
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_+_65154070 0.22 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr13_+_47127322 0.22 ENST00000389798.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr3_-_45838011 0.22 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr17_-_79805146 0.22 ENST00000415593.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr19_-_54804173 0.22 ENST00000391744.3
ENST00000251390.3
LILRA3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr8_+_12809093 0.21 ENST00000528753.2
KIAA1456
KIAA1456
chr19_-_13261160 0.21 ENST00000343587.5
ENST00000591197.1
STX10
syntaxin 10
chr14_-_102771462 0.21 ENST00000522874.1
MOK
MOK protein kinase
chr9_+_111624577 0.21 ENST00000333999.3
ACTL7A
actin-like 7A
chr19_-_13261090 0.21 ENST00000588848.1
STX10
syntaxin 10
chr16_+_28834303 0.20 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L
ataxin 2-like
chr12_+_3069037 0.20 ENST00000397122.2
TEAD4
TEA domain family member 4
chr14_-_102771516 0.20 ENST00000524214.1
ENST00000193029.6
ENST00000361847.2
MOK
MOK protein kinase
chr1_+_154474689 0.20 ENST00000368482.4
TDRD10
tudor domain containing 10
chr11_+_113779704 0.20 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr18_-_44550534 0.20 ENST00000451265.1
TCEB3CL
transcription elongation factor B polypeptide 3C-like

Network of associatons between targets according to the STRING database.

First level regulatory network of VDR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.6 1.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.6 1.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.6 3.5 GO:0007296 vitellogenesis(GO:0007296)
0.4 1.8 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.4 2.1 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4 1.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 2.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.3 1.0 GO:0045062 extrathymic T cell selection(GO:0045062)
0.3 1.7 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 1.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.3 1.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 1.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.9 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.2 0.5 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 1.6 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0042138 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.4 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 1.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.1 1.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.8 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.3 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.7 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 10.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 2.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.4 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.5 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 1.5 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.1 1.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 2.0 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.5 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 2.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.8 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.3 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.5 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 2.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0044828 positive regulation of translational initiation in response to stress(GO:0032058) negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 1.6 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.6 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.4 GO:0015824 proline transport(GO:0015824)
0.0 0.7 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.0 0.7 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 1.0 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.7 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 1.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.1 GO:0030516 regulation of axon extension(GO:0030516)
0.0 1.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.5 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 2.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880) osteoblast fate commitment(GO:0002051)
0.0 0.0 GO:0061744 psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0 0.3 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 1.9 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.5 1.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 2.8 GO:0005579 membrane attack complex(GO:0005579)
0.2 2.1 GO:0097443 sorting endosome(GO:0097443)
0.1 1.1 GO:0036128 CatSper complex(GO:0036128)
0.1 1.8 GO:0043203 axon hillock(GO:0043203)
0.1 0.6 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.4 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.6 GO:0045180 basal cortex(GO:0045180)
0.1 3.3 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 3.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 4.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0070761 PCAF complex(GO:0000125) pre-snoRNP complex(GO:0070761)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 1.6 GO:0034702 ion channel complex(GO:0034702)
0.0 1.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 4.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 2.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 1.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.4 1.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.3 1.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 0.9 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.3 0.8 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.3 1.5 GO:0045569 TRAIL binding(GO:0045569)
0.2 1.2 GO:0070404 NADH binding(GO:0070404)
0.2 1.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.2 1.7 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 1.5 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2 2.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 0.8 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 2.8 GO:0019841 retinol binding(GO:0019841)
0.1 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.0 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 2.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 9.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0005165 neurotrophin receptor binding(GO:0005165)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 1.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.5 REACTOME KINESINS Genes involved in Kinesins
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins