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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for XBP1

Z-value: 0.79

Motif logo

Transcription factors associated with XBP1

Gene Symbol Gene ID Gene Info
ENSG00000100219.12 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
XBP1hg19_v2_chr22_-_29196030_29196121,
hg19_v2_chr22_-_29196546_29196585
-0.125.2e-01Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_25228669 1.78 ENST00000216962.4
phosphorylase, glycogen; brain
chr19_-_49015050 1.57 ENST00000600059.1
lemur tyrosine kinase 3
chr9_+_124461603 1.39 ENST00000373782.3
DAB2 interacting protein
chr11_-_64646086 1.22 ENST00000320631.3
EH-domain containing 1
chr12_-_28122980 1.21 ENST00000395868.3
ENST00000534890.1
parathyroid hormone-like hormone
chr10_+_102106829 1.16 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr5_+_9546306 1.13 ENST00000508179.1
small nucleolar RNA host gene 18 (non-protein coding)
chr7_-_128045984 1.04 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr11_+_69455855 0.97 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr12_-_28123206 0.97 ENST00000542963.1
ENST00000535992.1
parathyroid hormone-like hormone
chr3_-_57583185 0.93 ENST00000463880.1
ADP-ribosylation factor 4
chr2_-_220408430 0.92 ENST00000243776.6
chondroitin polymerizing factor
chr20_+_32951070 0.89 ENST00000535650.1
ENST00000262650.6
itchy E3 ubiquitin protein ligase
chr3_+_171758344 0.89 ENST00000336824.4
ENST00000423424.1
fibronectin type III domain containing 3B
chr3_-_10362725 0.87 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13 homolog (S. cerevisiae)
chr2_-_216003127 0.81 ENST00000412081.1
ENST00000272895.7
ATP-binding cassette, sub-family A (ABC1), member 12
chr17_+_15848231 0.78 ENST00000304222.2
adenosine A2b receptor
chr6_+_41606176 0.76 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr20_+_44044717 0.75 ENST00000279036.6
ENST00000279035.9
ENST00000372689.5
ENST00000545755.1
ENST00000341555.5
ENST00000535404.1
ENST00000543458.2
ENST00000432270.1
phosphatidylinositol glycan anchor biosynthesis, class T
chr2_+_64681219 0.74 ENST00000238875.5
lectin, galactoside-binding-like
chr1_+_21835858 0.70 ENST00000539907.1
ENST00000540617.1
ENST00000374840.3
alkaline phosphatase, liver/bone/kidney
chr14_-_23834411 0.70 ENST00000429593.2
embryonal Fyn-associated substrate
chr5_+_154237778 0.67 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CCR4-NOT transcription complex, subunit 8
chr2_-_15701422 0.65 ENST00000441750.1
ENST00000281513.5
neuroblastoma amplified sequence
chr17_+_8339164 0.64 ENST00000582665.1
ENST00000334527.7
ENST00000299734.7
nudE neurodevelopment protein 1-like 1
chr6_-_7313381 0.64 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr12_-_99038732 0.64 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBKB interacting protein
chr17_+_8339189 0.63 ENST00000585098.1
ENST00000380025.4
ENST00000402554.3
ENST00000584866.1
ENST00000582490.1
nudE neurodevelopment protein 1-like 1
chr17_-_40575535 0.63 ENST00000357037.5
polymerase I and transcript release factor
chr1_-_24126051 0.60 ENST00000445705.1
UDP-galactose-4-epimerase
chr19_+_16187816 0.59 ENST00000588410.1
tropomyosin 4
chr9_-_35732362 0.58 ENST00000314888.9
ENST00000540444.1
talin 1
chr3_-_105588231 0.58 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr4_-_119757239 0.58 ENST00000280551.6
SEC24 family member D
chr7_+_100547156 0.57 ENST00000379458.4
Protein LOC100131514
chr22_+_45148432 0.57 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
Rho GTPase activating protein 8
chr15_+_79603404 0.57 ENST00000299705.5
transmembrane emp24 protein transport domain containing 3
chr19_-_22379753 0.56 ENST00000397121.2
zinc finger protein 676
chr3_+_127771212 0.55 ENST00000243253.3
ENST00000481210.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr1_-_144932464 0.55 ENST00000479408.2
phosphodiesterase 4D interacting protein
chr6_-_43596899 0.54 ENST00000307126.5
ENST00000452781.1
GTP binding protein 2
chr1_-_119682812 0.53 ENST00000537870.1
tryptophanyl tRNA synthetase 2, mitochondrial
chrX_-_41782249 0.53 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr10_-_22292675 0.53 ENST00000376946.1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr10_+_112257596 0.53 ENST00000369583.3
dual specificity phosphatase 5
chr21_+_45138941 0.53 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_-_24126023 0.53 ENST00000429356.1
UDP-galactose-4-epimerase
chr11_-_66056478 0.52 ENST00000431556.2
ENST00000528575.1
Yip1 interacting factor homolog A (S. cerevisiae)
chr22_+_46476192 0.52 ENST00000443490.1
hsa-mir-4763
chr7_-_30066233 0.51 ENST00000222803.5
FK506 binding protein 14, 22 kDa
chr17_-_8059638 0.50 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
period circadian clock 1
chr2_+_85132749 0.49 ENST00000233143.4
thymosin beta 10
chr1_+_26758790 0.48 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
dehydrodolichyl diphosphate synthase
chr8_-_124054362 0.47 ENST00000405944.3
derlin 1
chr3_-_156272924 0.46 ENST00000467789.1
ENST00000265044.2
signal sequence receptor, gamma (translocon-associated protein gamma)
chr19_+_1026566 0.46 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
calponin 2
chr8_-_124054484 0.45 ENST00000419562.2
derlin 1
chr5_-_171881362 0.44 ENST00000519643.1
SH3 and PX domains 2B
chr20_+_32951041 0.44 ENST00000374864.4
itchy E3 ubiquitin protein ligase
chr18_-_34408802 0.44 ENST00000590842.1
tubulin polyglutamylase complex subunit 2
chr19_-_4670345 0.43 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr3_-_28390298 0.43 ENST00000457172.1
5-azacytidine induced 2
chr7_+_128379449 0.43 ENST00000479257.1
calumenin
chr11_-_207221 0.42 ENST00000486280.1
ENST00000332865.6
ENST00000529614.2
ENST00000325147.9
ENST00000410108.1
ENST00000382762.3
Bet1 golgi vesicular membrane trafficking protein-like
chr19_+_17186577 0.42 ENST00000595618.1
ENST00000594824.1
myosin IXB
chr9_+_139377947 0.42 ENST00000354376.1
chromosome 9 open reading frame 163
chr3_-_128369643 0.42 ENST00000296255.3
ribophorin I
chr12_-_121712313 0.41 ENST00000392474.2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr17_+_72199721 0.40 ENST00000439590.2
ENST00000311111.6
ENST00000584577.1
ENST00000534490.1
ENST00000528433.2
ENST00000533498.1
ribosomal protein L38
chr14_+_96342729 0.39 ENST00000504119.1
long intergenic non-protein coding RNA 617
chr5_+_154238042 0.39 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CCR4-NOT transcription complex, subunit 8
chr4_+_141445311 0.39 ENST00000323570.3
ENST00000511887.2
ELMO/CED-12 domain containing 2
chr5_-_176730676 0.38 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24, member RAS oncogene family
chr19_+_47104553 0.38 ENST00000598871.1
ENST00000594523.1
calmodulin 3 (phosphorylase kinase, delta)
chr5_+_154238149 0.38 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CCR4-NOT transcription complex, subunit 8
chrX_-_41782683 0.37 ENST00000378163.1
ENST00000378154.1
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr1_-_145039949 0.37 ENST00000313382.9
phosphodiesterase 4D interacting protein
chr13_+_46039037 0.37 ENST00000349995.5
component of oligomeric golgi complex 3
chr1_-_119683251 0.37 ENST00000369426.5
ENST00000235521.4
tryptophanyl tRNA synthetase 2, mitochondrial
chr12_-_106641728 0.37 ENST00000378026.4
cytoskeleton-associated protein 4
chr4_-_119757322 0.36 ENST00000379735.5
SEC24 family member D
chr19_-_19030157 0.35 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
coatomer protein complex, subunit epsilon
chr1_-_11120057 0.35 ENST00000376957.2
spermidine synthase
chr7_-_6523688 0.35 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr6_-_111927062 0.34 ENST00000359831.4
TRAF3 interacting protein 2
chr7_+_116593953 0.34 ENST00000397750.3
ST7 overlapping transcript 4
chr19_+_39421556 0.33 ENST00000407800.2
ENST00000402029.3
mitochondrial ribosomal protein S12
chr3_-_149688896 0.32 ENST00000239940.7
profilin 2
chr3_-_105587879 0.31 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_+_56862301 0.31 ENST00000338146.5
SPRY domain containing 4
chr3_+_33155525 0.30 ENST00000449224.1
cartilage associated protein
chr6_+_63921351 0.30 ENST00000370659.1
FK506 binding protein 1C
chr7_+_127292234 0.30 ENST00000354725.3
staphylococcal nuclease and tudor domain containing 1
chr4_+_190992087 0.29 ENST00000553598.1
double homeobox 4 like 7
chr5_-_171881491 0.29 ENST00000311601.5
SH3 and PX domains 2B
chr19_-_54618650 0.29 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr10_+_18948311 0.29 ENST00000377275.3
ADP-ribosylation factor-like 5B
chr11_-_66056596 0.29 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr20_-_33680588 0.29 ENST00000451813.2
ENST00000432634.2
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr8_+_105235572 0.28 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr19_+_42388437 0.28 ENST00000378152.4
ENST00000337665.4
Rho guanine nucleotide exchange factor (GEF) 1
chr20_-_17662705 0.28 ENST00000455029.2
ribosome binding protein 1
chr1_-_144932316 0.28 ENST00000313431.9
phosphodiesterase 4D interacting protein
chr8_-_124553437 0.27 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr3_+_50284321 0.27 ENST00000451956.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr7_+_128379346 0.27 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr7_-_12443501 0.27 ENST00000275358.3
von Willebrand factor D and EGF domains
chr10_+_32735030 0.27 ENST00000277657.6
ENST00000362006.5
coiled-coil domain containing 7
chr5_-_115177496 0.27 ENST00000274459.4
ENST00000509910.1
autophagy related 12
chr3_-_57583130 0.27 ENST00000303436.6
ADP-ribosylation factor 4
chr3_-_156272872 0.26 ENST00000476217.1
signal sequence receptor, gamma (translocon-associated protein gamma)
chr1_-_144932014 0.26 ENST00000529945.1
phosphodiesterase 4D interacting protein
chr9_+_15553055 0.26 ENST00000380701.3
coiled-coil domain containing 171
chr20_-_17662878 0.26 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
ribosome binding protein 1
chr5_+_154238096 0.26 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CCR4-NOT transcription complex, subunit 8
chr14_-_24664540 0.26 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
transmembrane 9 superfamily member 1
chr19_-_54619006 0.25 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr3_-_139108475 0.25 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
coatomer protein complex, subunit beta 2 (beta prime)
chr3_-_28390120 0.25 ENST00000334100.6
5-azacytidine induced 2
chr2_+_242254679 0.25 ENST00000428282.1
ENST00000360051.3
septin 2
chr14_+_39736299 0.24 ENST00000341502.5
ENST00000396158.2
ENST00000280083.3
CTAGE family, member 5
chr19_+_33182823 0.24 ENST00000397061.3
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr19_+_1491144 0.24 ENST00000233596.3
receptor accessory protein 6
chr10_+_64893039 0.23 ENST00000277746.6
ENST00000435510.2
nuclear receptor binding factor 2
chr12_+_56624436 0.23 ENST00000266980.4
ENST00000437277.1
solute carrier family 39 (zinc transporter), member 5
chr6_+_33168597 0.23 ENST00000374675.3
solute carrier family 39 (zinc transporter), member 7
chr19_-_58459039 0.23 ENST00000282308.3
ENST00000598928.1
zinc finger protein 256
chr1_+_87170577 0.22 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr5_-_121413974 0.22 ENST00000231004.4
lysyl oxidase
chr13_-_52027134 0.22 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr18_-_34408693 0.22 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
tubulin polyglutamylase complex subunit 2
chr5_+_176730769 0.22 ENST00000303204.4
ENST00000503216.1
PRELI domain containing 1
chr12_-_109125285 0.21 ENST00000552871.1
ENST00000261401.3
coronin, actin binding protein, 1C
chr4_+_128982430 0.21 ENST00000512292.1
ENST00000508819.1
La ribonucleoprotein domain family, member 1B
chr20_+_57267669 0.21 ENST00000356091.6
aminopeptidase-like 1
chr3_+_132378741 0.20 ENST00000493720.2
ubiquitin-like modifier activating enzyme 5
chr2_+_171785824 0.20 ENST00000452526.2
golgi reassembly stacking protein 2, 55kDa
chr17_-_74068707 0.20 ENST00000307877.2
signal recognition particle 68kDa
chr19_+_47104493 0.20 ENST00000291295.9
ENST00000597743.1
calmodulin 3 (phosphorylase kinase, delta)
chr17_-_74068567 0.20 ENST00000355113.5
ENST00000539137.1
signal recognition particle 68kDa
chr3_-_28390415 0.20 ENST00000414162.1
ENST00000420543.2
5-azacytidine induced 2
chr10_+_75504105 0.19 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24 family member C
chr6_+_33168637 0.19 ENST00000374677.3
solute carrier family 39 (zinc transporter), member 7
chr14_+_39736582 0.18 ENST00000556148.1
ENST00000348007.3
CTAGE family, member 5
chr6_-_34664612 0.18 ENST00000374023.3
ENST00000374026.3
chromosome 6 open reading frame 106
chr2_+_27255806 0.18 ENST00000238788.9
ENST00000404032.3
transmembrane protein 214
chr6_+_116692102 0.18 ENST00000359564.2
dermatan sulfate epimerase
chr14_-_24664776 0.18 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
transmembrane 9 superfamily member 1
chr6_+_7107999 0.18 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr19_+_50353944 0.17 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
prostate tumor overexpressed 1
chr8_-_124054587 0.17 ENST00000259512.4
derlin 1
chr11_-_59383617 0.17 ENST00000263847.1
oxysterol binding protein
chr12_+_58120044 0.17 ENST00000542466.2
AGAP2 antisense RNA 1
chrX_-_153059811 0.17 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
isocitrate dehydrogenase 3 (NAD+) gamma
chr1_-_155145721 0.16 ENST00000295682.4
keratinocyte associated protein 2
chr1_+_63788730 0.16 ENST00000371116.2
forkhead box D3
chr12_-_91348949 0.15 ENST00000358859.2
coiled-coil glutamate-rich protein 1
chr18_-_46987000 0.15 ENST00000442713.2
ENST00000269445.6
dymeclin
chr12_+_48722763 0.15 ENST00000335017.1
H1 histone family, member N, testis-specific
chr5_+_112196919 0.14 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
signal recognition particle 19kDa
chr3_-_132378897 0.14 ENST00000545291.1
acyl-CoA dehydrogenase family, member 11
chr19_-_29704448 0.14 ENST00000304863.4
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chrX_+_153627231 0.14 ENST00000406022.2
ribosomal protein L10
chr5_+_126853301 0.13 ENST00000296666.8
ENST00000442138.2
ENST00000512635.2
proline-rich coiled-coil 1
chr3_-_57583052 0.13 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr22_+_21271714 0.13 ENST00000354336.3
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr20_-_8000426 0.13 ENST00000527925.1
ENST00000246024.2
thioredoxin-related transmembrane protein 4
chr2_+_241508039 0.13 ENST00000270357.4
arginyl aminopeptidase (aminopeptidase B)-like 1
chr1_+_1567474 0.13 ENST00000356026.5
matrix metallopeptidase 23B
chr2_-_88927092 0.12 ENST00000303236.3
eukaryotic translation initiation factor 2-alpha kinase 3
chr2_-_38604398 0.12 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
atlastin GTPase 2
chrX_+_47050236 0.12 ENST00000377351.4
ubiquitin-like modifier activating enzyme 1
chr4_+_76649797 0.12 ENST00000538159.1
ENST00000514213.2
USO1 vesicle transport factor
chr2_+_242254507 0.12 ENST00000391973.2
septin 2
chr9_+_101984577 0.12 ENST00000223641.4
Sec61 beta subunit
chr1_-_87379785 0.12 ENST00000401030.3
ENST00000370554.1
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr19_+_7701985 0.11 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
syntaxin binding protein 2
chrX_+_153060090 0.11 ENST00000370086.3
ENST00000370085.3
signal sequence receptor, delta
chr1_-_22109682 0.11 ENST00000400301.1
ENST00000532737.1
ubiquitin specific peptidase 48
chr18_-_47018869 0.11 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr12_+_7053228 0.11 ENST00000540506.2
chromosome 12 open reading frame 57
chr12_+_107349497 0.11 ENST00000548125.1
ENST00000280756.4
chromosome 12 open reading frame 23
chr10_-_105615164 0.11 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr20_-_62199427 0.10 ENST00000427522.2
helicase with zinc finger 2, transcriptional coactivator
chr1_-_161087802 0.10 ENST00000368010.3
prefoldin subunit 2
chr7_-_27183263 0.10 ENST00000222726.3
homeobox A5
chrX_-_153059958 0.10 ENST00000370092.3
ENST00000217901.5
isocitrate dehydrogenase 3 (NAD+) gamma
chr12_+_7053172 0.10 ENST00000229281.5
chromosome 12 open reading frame 57
chrX_+_153059608 0.09 ENST00000370087.1
signal sequence receptor, delta
chr1_+_249200395 0.09 ENST00000355360.4
ENST00000329291.5
ENST00000539153.1
piggyBac transposable element derived 2
chr12_+_7052974 0.09 ENST00000544681.1
ENST00000537087.1
chromosome 12 open reading frame 57
chr2_-_33824382 0.09 ENST00000238823.8
family with sequence similarity 98, member A
chr17_+_7184986 0.08 ENST00000317370.8
ENST00000571308.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr8_+_104384616 0.08 ENST00000520337.1
collagen triple helix repeat containing 1
chr21_+_45705752 0.08 ENST00000291582.5
autoimmune regulator
chr11_+_118443098 0.08 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
archain 1
chr21_-_18985158 0.08 ENST00000339775.6
BTG family, member 3
chr1_-_87380002 0.08 ENST00000331835.5
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr6_-_90062543 0.08 ENST00000435041.2
ubiquitin-conjugating enzyme E2, J1
chr19_+_36606654 0.08 ENST00000588385.1
ENST00000585746.1
tubulin folding cofactor B

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 1.4 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.3 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.2 0.7 GO:0071529 cementum mineralization(GO:0071529)
0.2 0.8 GO:0035627 ceramide transport(GO:0035627)
0.2 0.8 GO:0002880 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.2 0.6 GO:0039019 pronephric nephron development(GO:0039019)
0.2 1.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2 0.9 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.5 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 0.9 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 1.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 1.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 0.5 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 1.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.3 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.4 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.0 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.6 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 1.1 GO:0019388 galactose catabolic process(GO:0019388)
0.1 2.2 GO:0002076 osteoblast development(GO:0002076) negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.2 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.7 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.4 GO:0035459 cargo loading into vesicle(GO:0035459) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:1990737 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.4 GO:0048318 axial mesoderm development(GO:0048318)
0.0 1.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.8 GO:0060707 dorsal/ventral axis specification(GO:0009950) trophoblast giant cell differentiation(GO:0060707)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 1.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.0 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 1.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1990032 parallel fiber(GO:1990032)
0.4 1.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.3 1.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.2 1.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.6 GO:0070939 Dsl1p complex(GO:0070939)
0.2 1.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 2.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.9 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 2.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 1.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 1.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.3 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 0.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 0.8 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 1.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.9 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.5 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.2 0.5 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.6 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.4 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 3.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)