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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZBTB18

Z-value: 0.69

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Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ZBTB18
ENSG00000179456.9 zinc finger and BTB domain containing 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB18hg19_v2_chr1_+_244214577_244214593-0.846.1e-09Click!

Activity profile of ZBTB18 motif

Sorted Z-values of ZBTB18 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_100770328 3.01 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr2_+_113885138 2.65 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr3_-_111314230 2.31 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr4_+_75480629 2.22 ENST00000380846.3
AREGB
amphiregulin B
chr4_+_75310851 2.21 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr4_+_75311019 2.21 ENST00000502307.1
AREG
amphiregulin
chr9_+_125137565 2.11 ENST00000373698.5
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr15_-_74501360 1.77 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr21_+_30502806 1.76 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr11_-_62323702 1.62 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chrX_+_99899180 1.51 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr2_+_33359687 1.45 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr19_-_36001113 1.43 ENST00000434389.1
DMKN
dermokine
chr2_+_33359646 1.40 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr17_-_41174424 1.36 ENST00000355653.3
VAT1
vesicle amine transport 1
chr22_-_37823468 1.30 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr14_+_94577074 1.27 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr19_-_36001286 1.26 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr11_-_101454658 1.16 ENST00000344327.3
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr8_-_49833978 1.15 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr11_+_5410607 1.14 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr10_+_105253661 1.07 ENST00000369780.4
NEURL
neuralized E3 ubiquitin protein ligase 1
chr11_-_5537920 1.02 ENST00000380184.1
UBQLNL
ubiquilin-like
chr8_-_49834299 0.97 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr5_-_151304337 0.93 ENST00000455880.2
ENST00000545569.1
ENST00000274576.4
GLRA1
glycine receptor, alpha 1
chr11_+_65405556 0.90 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chrY_-_2655644 0.89 ENST00000525526.2
ENST00000534739.2
ENST00000383070.1
SRY
sex determining region Y
chr9_+_116263639 0.88 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr1_+_78354297 0.88 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr4_-_152149033 0.87 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr2_+_108994466 0.87 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr15_+_67418047 0.87 ENST00000540846.2
SMAD3
SMAD family member 3
chr9_+_116263778 0.86 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chrX_+_43515467 0.85 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr10_-_71332994 0.83 ENST00000242462.4
NEUROG3
neurogenin 3
chr3_-_37216055 0.83 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chrX_+_150151824 0.79 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chr4_+_15376165 0.79 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr19_+_39903185 0.77 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_-_34379546 0.76 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr20_+_30467600 0.76 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr16_-_30393752 0.73 ENST00000566517.1
ENST00000605106.1
SEPT1
SEPT1
septin 1
Uncharacterized protein
chr19_-_10341948 0.72 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr12_+_112563303 0.71 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr11_+_15136462 0.70 ENST00000379556.3
ENST00000424273.1
INSC
inscuteable homolog (Drosophila)
chr6_-_163148780 0.69 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
PARK2
parkin RBR E3 ubiquitin protein ligase
chr17_+_36584662 0.67 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr12_+_112563335 0.66 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr12_-_54785074 0.66 ENST00000338010.5
ENST00000550774.1
ZNF385A
zinc finger protein 385A
chr10_+_11206925 0.65 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr10_-_95241951 0.63 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr13_-_33780133 0.63 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr8_+_38965048 0.62 ENST00000399831.3
ENST00000437682.2
ENST00000519315.1
ENST00000379907.4
ENST00000522506.1
ADAM32
ADAM metallopeptidase domain 32
chr17_+_48638371 0.62 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr12_-_102874102 0.61 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr10_-_95242044 0.61 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr15_+_55611128 0.60 ENST00000164305.5
ENST00000539642.1
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr12_-_54785054 0.58 ENST00000352268.6
ENST00000549962.1
ZNF385A
zinc finger protein 385A
chr8_+_104831472 0.57 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr11_+_76494253 0.57 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr15_-_55611306 0.55 ENST00000563262.1
RAB27A
RAB27A, member RAS oncogene family
chr2_-_163099885 0.54 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr15_-_31453157 0.54 ENST00000559177.1
ENST00000558445.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr12_-_104443890 0.53 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2
glycosyltransferase 8 domain containing 2
chr3_+_100211412 0.52 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A
transmembrane protein 45A
chr3_+_49840685 0.50 ENST00000333323.4
FAM212A
family with sequence similarity 212, member A
chr16_+_6069586 0.50 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_11058847 0.49 ENST00000297303.4
ENST00000416569.2
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr5_+_140782351 0.49 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chr19_+_48673949 0.48 ENST00000328759.7
C19orf68
chromosome 19 open reading frame 68
chr15_-_31453359 0.48 ENST00000542188.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr2_-_163100045 0.47 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr3_-_52273098 0.45 ENST00000499914.2
ENST00000305533.5
ENST00000597542.1
TWF2
TLR9
twinfilin actin-binding protein 2
toll-like receptor 9
chr10_+_97733786 0.45 ENST00000371198.2
CC2D2B
coiled-coil and C2 domain containing 2B
chr2_+_201994042 0.45 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr4_+_156824840 0.45 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr16_-_30394143 0.44 ENST00000321367.3
ENST00000571393.1
SEPT1
septin 1
chr9_+_72658490 0.44 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr11_-_94227029 0.44 ENST00000323977.3
ENST00000536754.1
ENST00000323929.3
MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
chr2_-_85829496 0.44 ENST00000409668.1
TMEM150A
transmembrane protein 150A
chr1_+_186265399 0.44 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr1_+_32608566 0.43 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr11_+_71249071 0.43 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr2_-_85829811 0.40 ENST00000306353.3
TMEM150A
transmembrane protein 150A
chr5_+_159895275 0.39 ENST00000517927.1
MIR146A
microRNA 146a
chr6_+_160542870 0.39 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr6_+_160542821 0.38 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr7_-_122339162 0.38 ENST00000340112.2
RNF133
ring finger protein 133
chr14_+_64971292 0.38 ENST00000358738.3
ENST00000394712.2
ZBTB1
zinc finger and BTB domain containing 1
chr12_+_2162447 0.38 ENST00000335762.5
ENST00000399655.1
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr15_-_74501310 0.37 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr4_-_100009856 0.36 ENST00000296412.8
ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide
chr8_+_1772132 0.36 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr14_+_67707826 0.36 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chrX_+_48242863 0.35 ENST00000376886.2
ENST00000375517.3
SSX4
synovial sarcoma, X breakpoint 4
chr11_-_94226964 0.35 ENST00000538923.1
ENST00000540013.1
ENST00000407439.3
ENST00000393241.4
MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
chr3_+_159570722 0.35 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_-_85829780 0.34 ENST00000334462.5
TMEM150A
transmembrane protein 150A
chr3_+_101659682 0.34 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr18_+_3448455 0.33 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chrX_+_123480375 0.31 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr15_-_74043816 0.31 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr16_-_49698136 0.31 ENST00000535559.1
ZNF423
zinc finger protein 423
chr20_+_57875758 0.31 ENST00000395654.3
EDN3
endothelin 3
chrX_-_77225135 0.30 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr6_+_155537771 0.30 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr3_+_121311966 0.30 ENST00000338040.4
FBXO40
F-box protein 40
chr11_+_128562372 0.30 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_-_8263538 0.30 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr10_+_98064085 0.29 ENST00000419175.1
ENST00000371174.2
DNTT
DNA nucleotidylexotransferase
chrX_-_30877837 0.29 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr3_-_160167301 0.29 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr9_+_118916082 0.29 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr5_+_49962495 0.28 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr20_+_57875658 0.28 ENST00000371025.3
EDN3
endothelin 3
chr11_+_59824060 0.27 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr14_-_38725573 0.27 ENST00000342213.2
CLEC14A
C-type lectin domain family 14, member A
chr3_-_160167508 0.26 ENST00000479460.1
TRIM59
tripartite motif containing 59
chr2_+_189839046 0.26 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr19_+_50936142 0.25 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr11_+_59824127 0.25 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chrY_-_21239221 0.25 ENST00000447937.1
ENST00000331787.2
TTTY14
testis-specific transcript, Y-linked 14 (non-protein coding)
chr1_+_26856236 0.25 ENST00000374168.2
ENST00000374166.4
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chrX_-_19688475 0.25 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr6_-_163148700 0.23 ENST00000366894.1
ENST00000338468.3
PARK2
parkin RBR E3 ubiquitin protein ligase
chr2_+_177053307 0.23 ENST00000331462.4
HOXD1
homeobox D1
chrX_+_103031758 0.23 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr3_+_124303472 0.23 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chrX_+_123480194 0.22 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr21_-_34186006 0.22 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr1_-_2458026 0.22 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chrX_+_123480421 0.22 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr15_+_51669444 0.21 ENST00000396399.2
GLDN
gliomedin
chr3_-_160167540 0.20 ENST00000496222.1
ENST00000471396.1
ENST00000471155.1
ENST00000309784.4
TRIM59
tripartite motif containing 59
chr16_-_87367879 0.19 ENST00000568879.1
RP11-178L8.4
RP11-178L8.4
chr19_-_15918936 0.19 ENST00000334920.2
OR10H1
olfactory receptor, family 10, subfamily H, member 1
chr2_+_152214098 0.19 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr8_+_21823726 0.19 ENST00000433566.4
XPO7
exportin 7
chr1_-_11907829 0.19 ENST00000376480.3
NPPA
natriuretic peptide A
chr7_+_95115210 0.19 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr17_+_75369167 0.18 ENST00000423034.2
SEPT9
septin 9
chr11_+_5509915 0.18 ENST00000322641.5
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr2_-_74692473 0.17 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
MOGS
mannosyl-oligosaccharide glucosidase
chr7_+_97361388 0.17 ENST00000350485.4
ENST00000346867.4
TAC1
tachykinin, precursor 1
chrX_+_103031421 0.16 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr22_-_37213554 0.16 ENST00000443735.1
PVALB
parvalbumin
chr17_-_62050278 0.16 ENST00000578147.1
ENST00000435607.1
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr13_-_46964177 0.16 ENST00000389908.3
KIAA0226L
KIAA0226-like
chr1_-_113160826 0.16 ENST00000538187.1
ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr11_-_57089671 0.16 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr7_+_97361218 0.15 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr15_+_92937058 0.15 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr12_-_53893227 0.14 ENST00000547488.1
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr19_-_13947099 0.14 ENST00000587762.1
MIR24-2
microRNA 24-2
chr7_+_62809239 0.14 ENST00000456890.1
AC006455.1
AC006455.1
chr1_+_78354175 0.13 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr4_-_111563076 0.13 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr5_+_132009675 0.13 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr18_+_54814288 0.12 ENST00000585477.1
BOD1L2
biorientation of chromosomes in cell division 1-like 2
chr19_+_11649532 0.12 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1
calponin 1, basic, smooth muscle
chr13_+_113777105 0.12 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
F10
coagulation factor X
chr12_+_26126681 0.10 ENST00000542865.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr5_-_149324306 0.10 ENST00000255266.5
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr1_-_156647189 0.10 ENST00000368223.3
NES
nestin
chr7_+_120969045 0.10 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr4_+_88571429 0.09 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr6_-_74363803 0.09 ENST00000355773.5
SLC17A5
solute carrier family 17 (acidic sugar transporter), member 5
chrX_+_150151752 0.08 ENST00000325307.7
HMGB3
high mobility group box 3
chr17_-_67138015 0.07 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr16_-_67185117 0.06 ENST00000449549.3
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr19_-_52148798 0.06 ENST00000534261.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr12_-_48119301 0.05 ENST00000545824.2
ENST00000422538.3
ENDOU
endonuclease, polyU-specific
chrX_-_110513703 0.05 ENST00000324068.1
CAPN6
calpain 6
chr17_+_77020325 0.05 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_-_63684316 0.05 ENST00000301459.4
RCOR2
REST corepressor 2
chr11_+_46366918 0.05 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr17_+_32907768 0.04 ENST00000321639.5
TMEM132E
transmembrane protein 132E
chr15_+_31619013 0.04 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr3_-_105588231 0.04 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr19_+_9251052 0.03 ENST00000247956.6
ENST00000360385.3
ZNF317
zinc finger protein 317
chr17_+_77020224 0.03 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr12_-_48119340 0.03 ENST00000229003.3
ENDOU
endonuclease, polyU-specific
chr3_+_124303539 0.02 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr17_+_32612687 0.02 ENST00000305869.3
CCL11
chemokine (C-C motif) ligand 11
chr19_+_7584088 0.02 ENST00000394341.2
ZNF358
zinc finger protein 358
chr8_+_24241789 0.02 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr3_-_44552094 0.02 ENST00000436261.1
ZNF852
zinc finger protein 852
chr2_+_90139056 0.01 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr5_+_140792614 0.01 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chrX_-_111923145 0.01 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr17_+_64961026 0.00 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.7 2.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6 4.4 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.5 1.0 GO:0097325 melanocyte proliferation(GO:0097325)
0.4 2.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.4 2.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 2.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 2.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 1.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.9 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 0.9 GO:0042631 cellular response to water deprivation(GO:0042631)
0.2 0.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.3 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 2.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.6 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.4 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.5 GO:1901895 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.8 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 1.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.8 GO:0060290 transdifferentiation(GO:0060290)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.9 GO:2000020 positive regulation of male gonad development(GO:2000020)
0.1 1.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:0098912 calcium-mediated signaling using extracellular calcium source(GO:0035585) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.7 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 1.3 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 1.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0032009 early phagosome(GO:0032009)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.6 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 3.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.6 2.9 GO:0050436 microfibril binding(GO:0050436)
0.5 2.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.8 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 4.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 1.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 1.5 GO:0019838 growth factor binding(GO:0019838)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 2.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 5.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 4.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 2.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism