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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZBTB33_CHD2

Z-value: 2.24

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Transcription factors associated with ZBTB33_CHD2

Gene Symbol Gene ID Gene Info
ZBTB33
ENSG00000177485.6 zinc finger and BTB domain containing 33
CHD2
ENSG00000173575.14 chromodomain helicase DNA binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB33hg19_v2_chrX_+_119384607_1193847200.735.8e-06Click!
CHD2hg19_v2_chr15_+_93443419_93443580-0.478.7e-03Click!

Activity profile of ZBTB33_CHD2 motif

Sorted Z-values of ZBTB33_CHD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_7761013 29.27 ENST00000571846.1
CYB5D1
cytochrome b5 domain containing 1
chr17_+_7761301 22.72 ENST00000332439.4
ENST00000570446.1
CYB5D1
cytochrome b5 domain containing 1
chr10_-_75118611 9.99 ENST00000355577.3
ENST00000394865.1
ENST00000310715.3
ENST00000401621.2
TTC18
tetratricopeptide repeat domain 18
chr22_+_45809560 9.98 ENST00000342894.3
ENST00000538017.1
RIBC2
RIB43A domain with coiled-coils 2
chr10_-_75118471 9.88 ENST00000340329.3
TTC18
tetratricopeptide repeat domain 18
chr3_+_108308513 9.46 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr2_-_207629997 9.37 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chrX_+_53449887 9.31 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr2_-_207630033 8.89 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr2_-_99757977 8.73 ENST00000355053.4
TSGA10
testis specific, 10
chr15_+_75287861 8.47 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5
secretory carrier membrane protein 5
chrY_+_15016725 7.34 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr17_+_7591639 6.50 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr11_+_71791849 6.37 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr2_-_99757876 6.22 ENST00000539964.1
ENST00000393482.3
TSGA10
testis specific, 10
chr15_-_56757329 5.97 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr17_+_7591747 5.88 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chrX_+_53449805 5.71 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr15_+_22833395 5.59 ENST00000283645.4
TUBGCP5
tubulin, gamma complex associated protein 5
chr4_-_17812309 5.15 ENST00000382247.1
ENST00000536863.1
DCAF16
DDB1 and CUL4 associated factor 16
chr11_+_71791693 5.06 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_93781750 4.88 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr15_+_22833482 4.82 ENST00000453949.2
TUBGCP5
tubulin, gamma complex associated protein 5
chr15_-_48470544 4.69 ENST00000267836.6
MYEF2
myelin expression factor 2
chr11_+_71791803 4.66 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr16_+_89724188 4.26 ENST00000301031.4
ENST00000566204.1
ENST00000579310.1
SPATA33
spermatogenesis associated 33
chr6_+_116937636 4.17 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr4_-_16085340 4.03 ENST00000508167.1
PROM1
prominin 1
chr4_-_16085314 3.99 ENST00000510224.1
PROM1
prominin 1
chrY_+_15016013 3.88 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr16_+_89724434 3.75 ENST00000568929.1
SPATA33
spermatogenesis associated 33
chr9_+_86595626 3.63 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr6_+_52285131 3.62 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr1_-_24741525 3.58 ENST00000374409.1
STPG1
sperm-tail PG-rich repeat containing 1
chr20_-_61569227 3.58 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
DIDO1
death inducer-obliterator 1
chr2_-_55844720 3.58 ENST00000345102.5
ENST00000272313.5
ENST00000407823.3
SMEK2
SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr20_-_34330129 3.52 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39
RNA binding motif protein 39
chr16_+_89724263 3.44 ENST00000564238.1
SPATA33
spermatogenesis associated 33
chr16_+_90089008 3.30 ENST00000268699.4
GAS8
growth arrest-specific 8
chr8_-_110704014 3.29 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU
syntabulin (syntaxin-interacting)
chr10_+_96305535 3.17 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr13_+_24153488 3.08 ENST00000382258.4
ENST00000382263.3
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr1_-_167906020 3.03 ENST00000458574.1
MPC2
mitochondrial pyruvate carrier 2
chr2_-_43823093 2.98 ENST00000405006.4
THADA
thyroid adenoma associated
chr1_-_207224307 2.96 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr1_+_19923454 2.96 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1
MINOS1
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr2_-_677369 2.85 ENST00000281017.3
TMEM18
transmembrane protein 18
chr11_-_118436707 2.72 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr1_-_167906277 2.69 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr15_-_48470558 2.68 ENST00000324324.7
MYEF2
myelin expression factor 2
chr13_-_21750659 2.62 ENST00000400018.3
ENST00000314759.5
SKA3
spindle and kinetochore associated complex subunit 3
chr10_-_28287968 2.55 ENST00000305242.5
ARMC4
armadillo repeat containing 4
chr9_+_26956371 2.54 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr11_-_118436606 2.51 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr12_+_56661033 2.39 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr11_+_71791359 2.39 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr13_+_115047097 2.33 ENST00000351487.5
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr4_+_40751914 2.33 ENST00000381782.2
ENST00000316607.5
NSUN7
NOP2/Sun domain family, member 7
chr3_-_160117301 2.31 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr8_-_42698433 2.28 ENST00000345117.2
ENST00000254250.3
THAP1
THAP domain containing, apoptosis associated protein 1
chr16_+_14165160 2.28 ENST00000574998.1
ENST00000571589.1
ENST00000574045.1
MKL2
MKL/myocardin-like 2
chr8_-_110703819 2.28 ENST00000532779.1
ENST00000534578.1
SYBU
syntabulin (syntaxin-interacting)
chrX_+_77154935 2.26 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr15_-_64126084 2.21 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr15_+_66797627 2.19 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr1_-_59165763 2.12 ENST00000472487.1
MYSM1
Myb-like, SWIRM and MPN domains 1
chr13_+_115047053 2.10 ENST00000375299.3
UPF3A
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr10_+_127408263 2.08 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr8_+_75896731 2.05 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr3_-_137893721 2.01 ENST00000505015.2
ENST00000260803.4
DBR1
debranching RNA lariats 1
chr22_+_23487513 2.00 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr1_-_174992544 1.96 ENST00000476371.1
MRPS14
mitochondrial ribosomal protein S14
chr2_-_25194963 1.95 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr5_-_10249990 1.94 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chr10_+_124768482 1.92 ENST00000368869.4
ENST00000358776.4
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr1_+_70820451 1.92 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr6_+_52285046 1.91 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr1_+_20512568 1.91 ENST00000375099.3
UBXN10
UBX domain protein 10
chr16_+_57481382 1.89 ENST00000564655.1
ENST00000567072.1
ENST00000567933.1
ENST00000563166.1
COQ9
coenzyme Q9
chr9_-_21031608 1.83 ENST00000513293.2
ENST00000495827.2
PTPLAD2
protein tyrosine phosphatase-like A domain containing 2
chr2_-_241497374 1.82 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ANKMY1
ankyrin repeat and MYND domain containing 1
chr15_+_66797455 1.82 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr4_+_186064395 1.81 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr6_-_43478239 1.79 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr16_-_84150492 1.78 ENST00000343411.3
MBTPS1
membrane-bound transcription factor peptidase, site 1
chr1_+_179923873 1.78 ENST00000367607.3
ENST00000491495.2
CEP350
centrosomal protein 350kDa
chr1_+_231473743 1.77 ENST00000295050.7
SPRTN
SprT-like N-terminal domain
chr1_+_3569129 1.76 ENST00000354437.4
ENST00000357733.3
ENST00000346387.4
TP73
tumor protein p73
chr6_+_18155632 1.74 ENST00000297792.5
KDM1B
lysine (K)-specific demethylase 1B
chr13_+_24734844 1.73 ENST00000382108.3
SPATA13
spermatogenesis associated 13
chr1_+_3569072 1.72 ENST00000378295.4
ENST00000604074.1
TP73
tumor protein p73
chr1_+_111992064 1.70 ENST00000483994.1
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr11_+_111848024 1.69 ENST00000315253.5
DIXDC1
DIX domain containing 1
chr15_-_73925651 1.68 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr17_+_53046096 1.67 ENST00000376352.2
ENST00000299341.4
ENST00000405898.1
ENST00000434978.2
ENST00000398391.2
STXBP4
syntaxin binding protein 4
chr1_+_26146397 1.64 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L
mitochondrial fission regulator 1-like
chr11_+_62104897 1.64 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1
asparaginase like 1
chr2_-_20101385 1.64 ENST00000431392.1
TTC32
tetratricopeptide repeat domain 32
chr17_-_4843206 1.63 ENST00000576951.1
SLC25A11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr14_-_92413727 1.63 ENST00000267620.10
FBLN5
fibulin 5
chr7_-_150038704 1.62 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr5_+_75699040 1.61 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr6_-_146285455 1.60 ENST00000367505.2
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr17_+_7590734 1.59 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr1_+_26146674 1.59 ENST00000525713.1
ENST00000374301.3
MTFR1L
mitochondrial fission regulator 1-like
chr5_+_75699149 1.58 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr2_-_43823119 1.58 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr13_-_41768654 1.57 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr14_+_65381079 1.56 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
CHURC1
FNTB
CHURC1-FNTB
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr4_+_48988259 1.56 ENST00000226432.4
CWH43
cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
chr20_+_30946106 1.53 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr1_+_183441500 1.53 ENST00000456731.2
SMG7
SMG7 nonsense mediated mRNA decay factor
chr15_+_44580899 1.53 ENST00000559222.1
ENST00000299957.6
CASC4
cancer susceptibility candidate 4
chr16_+_57481349 1.52 ENST00000262507.6
ENST00000565964.1
COQ9
coenzyme Q9
chr7_-_75677251 1.52 ENST00000431581.1
ENST00000359697.3
ENST00000451157.1
ENST00000340062.5
ENST00000360591.3
ENST00000248600.1
STYXL1
serine/threonine/tyrosine interacting-like 1
chr2_-_85555355 1.50 ENST00000282120.2
ENST00000398263.2
TGOLN2
trans-golgi network protein 2
chr2_+_149402553 1.49 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr1_-_223316611 1.46 ENST00000366881.1
TLR5
toll-like receptor 5
chr16_-_54320675 1.46 ENST00000329734.3
IRX3
iroquois homeobox 3
chr6_-_146285221 1.46 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr1_+_110577229 1.45 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr22_-_37172111 1.45 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr20_-_61569296 1.45 ENST00000370371.4
DIDO1
death inducer-obliterator 1
chr1_-_47779762 1.45 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL
SCL/TAL1 interrupting locus
chr8_+_16884740 1.43 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr2_+_170683942 1.43 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr22_-_37172191 1.42 ENST00000340630.5
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr7_+_99775366 1.42 ENST00000394018.2
ENST00000416412.1
STAG3
stromal antigen 3
chr2_+_170683979 1.41 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr8_+_81398444 1.40 ENST00000455036.3
ENST00000426744.2
ZBTB10
zinc finger and BTB domain containing 10
chr21_-_34144157 1.40 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr18_-_59854203 1.39 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
PIGN
phosphatidylinositol glycan anchor biosynthesis, class N
chr15_+_44580955 1.38 ENST00000345795.2
ENST00000360824.3
CASC4
cancer susceptibility candidate 4
chr5_+_56469843 1.37 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr6_+_18155560 1.34 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B
lysine (K)-specific demethylase 1B
chr2_-_160761179 1.34 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
LY75
LY75-CD302
lymphocyte antigen 75
LY75-CD302 readthrough
chr15_-_93616892 1.33 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
RGMA
repulsive guidance molecule family member a
chr17_-_37607497 1.32 ENST00000394287.3
ENST00000300651.6
MED1
mediator complex subunit 1
chr5_-_127418755 1.32 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
CTC-228N24.3
chr1_-_156252590 1.32 ENST00000361813.5
ENST00000368267.5
SMG5
SMG5 nonsense mediated mRNA decay factor
chr22_-_23484246 1.31 ENST00000216036.4
RTDR1
rhabdoid tumor deletion region gene 1
chr7_-_128171123 1.31 ENST00000608477.1
RP11-212P7.2
RP11-212P7.2
chr10_-_127408011 1.31 ENST00000531977.1
ENST00000527483.1
ENST00000525909.1
ENST00000528844.1
ENST00000423178.2
RP11-383C5.4
RP11-383C5.4
chr7_+_99775520 1.30 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3
stromal antigen 3
chr5_+_138629337 1.30 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3
matrin 3
chr17_-_2415169 1.30 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
METTL16
methyltransferase like 16
chr1_+_246887349 1.29 ENST00000366510.3
SCCPDH
saccharopine dehydrogenase (putative)
chr4_-_103748880 1.27 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr17_+_4843679 1.27 ENST00000576229.1
RNF167
ring finger protein 167
chr19_-_33555780 1.26 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr19_+_35168567 1.26 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr17_-_4843316 1.26 ENST00000544061.2
SLC25A11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr4_-_168155730 1.23 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr14_+_65007177 1.23 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chr2_-_10587897 1.22 ENST00000405333.1
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr14_-_20923195 1.21 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr19_+_12273866 1.21 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136
zinc finger protein 136
chr13_-_22178284 1.21 ENST00000468222.2
ENST00000382374.4
MICU2
mitochondrial calcium uptake 2
chrX_-_129402857 1.19 ENST00000447817.1
ENST00000370978.4
ZNF280C
zinc finger protein 280C
chr3_+_169684553 1.19 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr15_-_66649010 1.19 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr1_-_6614565 1.18 ENST00000377705.5
NOL9
nucleolar protein 9
chr6_-_107436473 1.18 ENST00000369042.1
BEND3
BEN domain containing 3
chr12_-_29534074 1.16 ENST00000546839.1
ENST00000360150.4
ENST00000552155.1
ENST00000550353.1
ENST00000548441.1
ENST00000552132.1
ERGIC2
ERGIC and golgi 2
chr14_-_64108125 1.16 ENST00000267522.3
WDR89
WD repeat domain 89
chr17_+_58755184 1.13 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr8_-_144691718 1.12 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
PYCRL
pyrroline-5-carboxylate reductase-like
chrX_-_80457385 1.11 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chr1_-_24306798 1.11 ENST00000374452.5
ENST00000492112.2
ENST00000343255.5
ENST00000344989.6
SRSF10
serine/arginine-rich splicing factor 10
chr1_+_28052456 1.11 ENST00000373954.6
ENST00000419687.2
FAM76A
family with sequence similarity 76, member A
chr19_-_1876156 1.11 ENST00000565797.1
CTB-31O20.2
CTB-31O20.2
chr3_+_42642106 1.10 ENST00000232978.8
NKTR
natural killer-tumor recognition sequence
chrX_+_40944871 1.10 ENST00000378308.2
ENST00000324545.8
USP9X
ubiquitin specific peptidase 9, X-linked
chr12_-_27091183 1.10 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN
asunder spermatogenesis regulator
chr7_+_99933730 1.09 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr19_+_35168633 1.09 ENST00000505365.2
ZNF302
zinc finger protein 302
chr17_+_55162453 1.09 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr11_+_94227129 1.08 ENST00000540349.1
ENST00000535502.1
ENST00000545130.1
ENST00000544253.1
ENST00000541144.1
ANKRD49
ankyrin repeat domain 49
chr16_+_57769635 1.07 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr1_-_70820357 1.06 ENST00000370944.4
ENST00000262346.6
ANKRD13C
ankyrin repeat domain 13C
chr16_-_18468926 1.06 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr3_+_49044798 1.04 ENST00000438660.1
ENST00000608424.1
ENST00000415265.2
WDR6
WD repeat domain 6
chr3_-_195270162 1.04 ENST00000438848.1
ENST00000328432.3
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr16_-_5147743 1.04 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
FAM86A
family with sequence similarity 86, member A
chr22_+_41865109 1.03 ENST00000216254.4
ENST00000396512.3
ACO2
aconitase 2, mitochondrial
chr18_-_53255766 1.03 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr22_+_29279552 1.02 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr17_+_79935418 1.02 ENST00000306729.7
ENST00000306739.4
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr2_+_24714729 1.01 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr9_-_136214877 1.00 ENST00000446777.1
ENST00000343730.5
ENST00000344469.5
ENST00000371999.1
ENST00000494177.2
ENST00000457204.2
MED22
mediator complex subunit 22
chr5_+_56469775 0.99 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr1_+_60280458 0.99 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chr1_+_41157671 0.98 ENST00000534399.1
ENST00000372653.1
NFYC
nuclear transcription factor Y, gamma
chr4_-_178363581 0.98 ENST00000264595.2
AGA
aspartylglucosaminidase
chr1_+_104068562 0.98 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr11_+_44087729 0.98 ENST00000524990.1
ENST00000263776.8
ACCS
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr2_-_157189180 0.98 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr13_+_21750780 0.96 ENST00000309594.4
MRP63
mitochondrial ribosomal protein 63
chr6_-_119399895 0.96 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr6_-_116575226 0.96 ENST00000420283.1
TSPYL4
TSPY-like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB33_CHD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0032203 telomere formation via telomerase(GO:0032203)
2.0 8.0 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.4 5.7 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
1.4 19.3 GO:0006108 malate metabolic process(GO:0006108)
1.2 3.6 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
1.2 10.6 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.1 4.6 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.1 3.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.9 3.7 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.9 17.8 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.6 2.4 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.6 3.6 GO:0015853 adenine transport(GO:0015853)
0.6 2.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.6 1.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.5 1.6 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.5 1.5 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.5 2.9 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.5 3.3 GO:1904526 regulation of microtubule binding(GO:1904526)
0.5 2.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.5 2.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.5 1.4 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.4 1.7 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
0.4 1.2 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.4 1.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.4 1.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.4 1.5 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.3 3.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.3 1.6 GO:0061760 antifungal innate immune response(GO:0061760)
0.3 2.2 GO:0080009 mRNA methylation(GO:0080009)
0.3 0.6 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.3 0.9 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.3 1.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.3 1.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 0.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 0.9 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.3 0.9 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 1.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.3 0.8 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.3 5.4 GO:0070986 left/right axis specification(GO:0070986)
0.3 1.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.3 1.6 GO:0018343 protein farnesylation(GO:0018343)
0.3 1.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.3 13.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 1.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.7 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.2 3.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 5.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 8.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 0.7 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.9 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.9 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.2 1.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.2 1.7 GO:0048478 replication fork protection(GO:0048478)
0.2 0.6 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 1.4 GO:0033504 floor plate development(GO:0033504)
0.2 0.6 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.2 1.0 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.6 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.2 2.8 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.2 1.6 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.2 0.8 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 1.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 1.6 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 0.5 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 3.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 1.6 GO:0006552 leucine catabolic process(GO:0006552)
0.2 0.5 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 2.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 0.9 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.6 GO:0048378 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) mesendoderm development(GO:0048382)
0.1 9.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.0 GO:0035900 response to isolation stress(GO:0035900)
0.1 3.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:0072642 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 0.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 2.2 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.1 1.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 1.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 0.5 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.8 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 1.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.7 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1 0.7 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 2.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.8 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 2.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 1.7 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.1 1.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 9.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 1.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.3 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.8 GO:0009414 response to water deprivation(GO:0009414)
0.1 2.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0006983 ER overload response(GO:0006983)
0.1 1.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.5 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 1.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 1.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 1.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.7 GO:0035461 pantothenate metabolic process(GO:0015939) vitamin transmembrane transport(GO:0035461)
0.1 1.1 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.1 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 4.4 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.1 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.3 GO:0072312 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 1.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.1 GO:0060661 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.0 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.8 GO:0032196 transposition(GO:0032196)
0.1 0.8 GO:0071468 cellular response to acidic pH(GO:0071468)
0.0 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 3.1 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 2.4 GO:0003341 cilium movement(GO:0003341)
0.0 1.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0015846 polyamine transport(GO:0015846)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 2.5 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 1.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.6 GO:0042330 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 0.8 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 1.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:2000825 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) positive regulation of androgen receptor activity(GO:2000825)
0.0 1.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 3.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.6 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 15.9 GO:0030031 cell projection assembly(GO:0030031)
0.0 0.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0097676 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.0 3.0 GO:0007004 telomere maintenance via telomerase(GO:0007004)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 1.0 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 1.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.2 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.6 GO:0043632 modification-dependent macromolecule catabolic process(GO:0043632)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0 1.2 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 1.8 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.3 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.3 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 1.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.3 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.9 GO:0032259 methylation(GO:0032259)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.0 GO:0006829 zinc II ion transport(GO:0006829)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0001534 radial spoke(GO:0001534)
1.4 9.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
1.2 10.6 GO:0000923 equatorial microtubule organizing center(GO:0000923)
1.0 4.0 GO:1990423 RZZ complex(GO:1990423)
0.5 2.2 GO:0032044 DSIF complex(GO:0032044)
0.5 14.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.5 1.5 GO:0034455 t-UTP complex(GO:0034455)
0.5 18.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.4 8.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 5.6 GO:0097433 dense body(GO:0097433)
0.4 2.1 GO:1990246 uniplex complex(GO:1990246)
0.4 1.6 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.4 3.0 GO:0061617 MICOS complex(GO:0061617)
0.3 1.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 1.6 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.3 2.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 1.8 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 5.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.2 2.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.9 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 0.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 1.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.6 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 0.8 GO:0060187 cell pole(GO:0060187)
0.2 4.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 0.5 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 0.2 GO:0043291 RAVE complex(GO:0043291)
0.2 1.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 1.6 GO:0071953 elastic fiber(GO:0071953)
0.2 1.6 GO:0044754 autolysosome(GO:0044754)
0.2 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 1.2 GO:0036128 CatSper complex(GO:0036128)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.1 16.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 1.1 GO:0005827 polar microtubule(GO:0005827)
0.1 0.8 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.8 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 4.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 5.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 3.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.0 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 6.6 GO:0000786 nucleosome(GO:0000786)
0.1 14.9 GO:0031514 motile cilium(GO:0031514)
0.1 1.2 GO:0031298 replication fork protection complex(GO:0031298)
0.1 2.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.3 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 8.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 3.0 GO:0016592 mediator complex(GO:0016592)
0.1 2.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.6 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.1 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 5.8 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0097539 clathrin complex(GO:0071439) ciliary transition fiber(GO:0097539)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 5.4 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 3.4 GO:0044450 microtubule organizing center part(GO:0044450)
0.0 1.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 9.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 19.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
2.1 18.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.8 2.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.7 2.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.7 5.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 1.8 GO:0030626 U12 snRNA binding(GO:0030626)
0.6 2.9 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.5 1.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.5 8.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.5 9.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.5 3.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.5 2.0 GO:0036033 mediator complex binding(GO:0036033)
0.5 1.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.5 1.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.4 17.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 1.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 1.6 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.4 1.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 1.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.3 3.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 0.9 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.3 0.8 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.3 2.1 GO:0048039 ubiquinone binding(GO:0048039)
0.3 3.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 1.7 GO:0046979 TAP2 binding(GO:0046979)
0.2 1.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 0.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 0.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.9 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 1.1 GO:0031208 POZ domain binding(GO:0031208)
0.2 0.8 GO:0004803 transposase activity(GO:0004803)
0.2 0.6 GO:0016730 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.2 1.3 GO:0050733 RS domain binding(GO:0050733)
0.2 0.9 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.2 0.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.5 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 1.8 GO:0015288 porin activity(GO:0015288)
0.2 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.7 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.5 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.2 1.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 5.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.4 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.6 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.7 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 1.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.8 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.6 GO:0000150 recombinase activity(GO:0000150)
0.1 0.4 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 4.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 8.0 GO:0042805 actinin binding(GO:0042805)
0.1 9.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.9 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 1.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.2 GO:0000182 rDNA binding(GO:0000182)
0.1 1.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.7 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 1.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.1 0.3 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 2.6 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 2.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 3.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.2 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.5 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0030492 hemoglobin binding(GO:0030492)
0.1 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 1.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 4.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.7 GO:0034062 RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 3.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 2.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0022821 calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.0 1.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.5 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 3.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.2 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 3.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)
0.0 1.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.9 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 3.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 13.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 1.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 2.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 2.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 5.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism