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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZBTB49

Z-value: 0.60

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Transcription factors associated with ZBTB49

Gene Symbol Gene ID Gene Info
ZBTB49
ENSG00000168826.11 zinc finger and BTB domain containing 49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB49hg19_v2_chr4_+_4291924_4292011-0.261.7e-01Click!

Activity profile of ZBTB49 motif

Sorted Z-values of ZBTB49 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51466681 7.02 ENST00000456750.2
KLK6
kallikrein-related peptidase 6
chr2_+_95691445 4.51 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
MAL
mal, T-cell differentiation protein
chr2_+_95691417 4.10 ENST00000309988.4
MAL
mal, T-cell differentiation protein
chr15_+_90728145 3.81 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr10_-_90751038 2.10 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr10_+_94352956 2.06 ENST00000260731.3
KIF11
kinesin family member 11
chrX_+_64887512 1.62 ENST00000360270.5
MSN
moesin
chr3_-_196756646 1.61 ENST00000439320.1
ENST00000296351.4
ENST00000296350.5
MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr15_+_75639773 1.48 ENST00000567657.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr22_-_37915247 1.45 ENST00000251973.5
CARD10
caspase recruitment domain family, member 10
chr17_-_80009650 1.38 ENST00000310496.4
RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_-_74582191 1.31 ENST00000225276.5
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr14_+_35591858 1.28 ENST00000603544.1
KIAA0391
KIAA0391
chr6_-_109777128 1.14 ENST00000358807.3
ENST00000358577.3
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr1_-_110933663 1.08 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr9_+_139553306 1.08 ENST00000371699.1
EGFL7
EGF-like-domain, multiple 7
chr11_+_117857063 1.04 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA
interleukin 10 receptor, alpha
chr1_-_110933611 0.99 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr6_-_49604545 0.84 ENST00000371175.4
ENST00000229810.7
RHAG
Rh-associated glycoprotein
chr5_-_146833222 0.81 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr8_-_82024290 0.79 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr22_-_20255212 0.77 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr2_+_89890533 0.76 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr3_-_51813009 0.75 ENST00000398780.3
IQCF6
IQ motif containing F6
chr3_-_49055991 0.74 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALRD3
DALR anticodon binding domain containing 3
chr14_+_35591735 0.73 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr6_-_153452356 0.69 ENST00000206262.1
RGS17
regulator of G-protein signaling 17
chr14_+_35591928 0.68 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr3_-_172428959 0.67 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
NCEH1
neutral cholesterol ester hydrolase 1
chr22_-_20256054 0.66 ENST00000043402.7
RTN4R
reticulon 4 receptor
chr5_+_154237778 0.60 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr9_-_123676827 0.59 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr8_+_95653302 0.58 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr22_-_19166343 0.57 ENST00000215882.5
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr14_-_74485960 0.56 ENST00000556242.1
ENST00000334696.6
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr19_+_17862274 0.55 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCHO1
FCH domain only 1
chrX_-_131623874 0.54 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr19_-_59070239 0.50 ENST00000595957.1
ENST00000253023.3
UBE2M
ubiquitin-conjugating enzyme E2M
chr6_-_43655511 0.49 ENST00000372133.3
ENST00000372116.1
ENST00000427312.1
MRPS18A
mitochondrial ribosomal protein S18A
chr11_+_4116005 0.49 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chr11_-_2950642 0.48 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr2_+_234160217 0.45 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr20_-_32700075 0.45 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr11_+_4116054 0.44 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr4_-_2243839 0.40 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
POLN
HAUS3
polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3
chr2_+_234160340 0.39 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
ATG16L1
autophagy related 16-like 1 (S. cerevisiae)
chr8_-_16043780 0.39 ENST00000445506.2
MSR1
macrophage scavenger receptor 1
chr10_+_64893039 0.38 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr3_+_196594727 0.36 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5
SUMO1/sentrin specific peptidase 5
chr16_+_81069433 0.35 ENST00000299575.4
ATMIN
ATM interactor
chr20_-_25320367 0.34 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr10_+_90750493 0.33 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr12_+_104324112 0.32 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr10_-_46641003 0.32 ENST00000395721.2
ENST00000374218.2
ENST00000395725.3
ENST00000374346.3
ENST00000417004.1
PTPN20A
protein tyrosine phosphatase, non-receptor type 20A
chrX_+_151903253 0.32 ENST00000452779.2
ENST00000370291.2
CSAG1
chondrosarcoma associated gene 1
chr10_+_81466084 0.31 ENST00000342531.2
NUTM2B
NUT family member 2B
chrX_+_52780318 0.29 ENST00000375515.3
ENST00000276049.6
SSX2B
synovial sarcoma, X breakpoint 2B
chr6_+_53659746 0.29 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr17_+_80009741 0.28 ENST00000578552.1
ENST00000320548.4
ENST00000581578.1
ENST00000583885.1
ENST00000583641.1
ENST00000581418.1
ENST00000355130.2
ENST00000306823.6
ENST00000392358.2
GPS1
G protein pathway suppressor 1
chr20_+_1115821 0.28 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr7_-_44613494 0.27 ENST00000431640.1
ENST00000258772.5
DDX56
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr19_-_4182530 0.26 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
SIRT6
sirtuin 6
chr3_+_52232102 0.26 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
ALAS1
aminolevulinate, delta-, synthase 1
chr17_+_74734052 0.25 ENST00000590514.1
MFSD11
major facilitator superfamily domain containing 11
chr3_-_196242233 0.24 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr22_-_42017021 0.24 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr8_-_99129384 0.24 ENST00000521560.1
ENST00000254878.3
HRSP12
heat-responsive protein 12
chr15_-_55489097 0.23 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr20_+_33134619 0.23 ENST00000374837.3
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr11_+_63993738 0.21 ENST00000441250.2
ENST00000279206.3
NUDT22
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr19_-_42894420 0.20 ENST00000597255.1
ENST00000222032.5
CNFN
cornifelin
chr5_+_154238096 0.19 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr5_-_77590480 0.19 ENST00000519295.1
ENST00000255194.6
AP3B1
adaptor-related protein complex 3, beta 1 subunit
chr18_-_11148587 0.18 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr16_+_28722684 0.17 ENST00000331666.6
ENST00000395587.1
ENST00000569690.1
ENST00000564243.1
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr8_+_58907104 0.16 ENST00000361488.3
FAM110B
family with sequence similarity 110, member B
chr2_-_48982708 0.16 ENST00000428232.1
ENST00000405626.1
ENST00000294954.7
LHCGR
luteinizing hormone/choriogonadotropin receptor
chr8_-_99129338 0.15 ENST00000520507.1
HRSP12
heat-responsive protein 12
chr5_+_154238042 0.14 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CNOT8
CCR4-NOT transcription complex, subunit 8
chrX_+_30265256 0.13 ENST00000397548.2
MAGEB1
melanoma antigen family B, 1
chr16_-_28415162 0.13 ENST00000398944.3
ENST00000398943.3
ENST00000380876.4
EIF3CL
eukaryotic translation initiation factor 3, subunit C-like
chr16_+_28722809 0.12 ENST00000566866.1
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr1_-_36863481 0.11 ENST00000315732.2
LSM10
LSM10, U7 small nuclear RNA associated
chr7_-_12443501 0.11 ENST00000275358.3
VWDE
von Willebrand factor D and EGF domains
chr19_+_18669809 0.09 ENST00000602094.1
KXD1
KxDL motif containing 1
chr8_+_99129513 0.08 ENST00000522319.1
ENST00000401707.2
POP1
processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
chr11_-_63993690 0.08 ENST00000394546.2
ENST00000541278.1
TRPT1
tRNA phosphotransferase 1
chr21_-_26979786 0.07 ENST00000419219.1
ENST00000352957.4
ENST00000307301.7
MRPL39
mitochondrial ribosomal protein L39
chr11_-_63993601 0.07 ENST00000545812.1
ENST00000394547.3
ENST00000317459.6
TRPT1
tRNA phosphotransferase 1
chr17_-_3195876 0.07 ENST00000323404.1
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr19_-_51611623 0.06 ENST00000421832.2
CTU1
cytosolic thiouridylase subunit 1
chr14_+_79745682 0.06 ENST00000557594.1
NRXN3
neurexin 3
chr19_+_50145328 0.06 ENST00000360565.3
SCAF1
SR-related CTD-associated factor 1
chr19_-_54567035 0.06 ENST00000366170.2
ENST00000425006.2
VSTM1
V-set and transmembrane domain containing 1
chr5_+_154238149 0.05 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8
CCR4-NOT transcription complex, subunit 8
chr17_+_54671047 0.04 ENST00000332822.4
NOG
noggin
chr1_+_26869597 0.03 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr6_-_159240415 0.02 ENST00000367075.3
EZR
ezrin
chr20_-_33735070 0.02 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr12_+_83080659 0.02 ENST00000321196.3
TMTC2
transmembrane and tetratricopeptide repeat containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 1.1 GO:0019417 sulfur oxidation(GO:0019417)
0.3 2.1 GO:0090131 mesenchyme migration(GO:0090131)
0.3 7.0 GO:0016540 protein autoprocessing(GO:0016540)
0.3 2.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.3 0.8 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.3 1.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.6 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.2 0.5 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.8 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 2.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.9 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 3.8 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.3 GO:0097527 Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.1 0.2 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.0 0.4 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 1.3 GO:0097503 sialylation(GO:0097503)
0.0 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 1.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.3 2.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.4 GO:0032449 CBM complex(GO:0032449)
0.2 0.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 1.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 8.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 1.4 GO:0038131 neuregulin receptor activity(GO:0038131)
0.3 1.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 0.8 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 0.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 2.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 3.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.7 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.6 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 2.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 7.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 2.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.1 REACTOME KINESINS Genes involved in Kinesins
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events