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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZIC1

Z-value: 0.71

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Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ZIC1
ENSG00000152977.5 Zic family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg19_v2_chr3_+_147127142_1471271710.029.3e-01Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_2182388 0.98 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr17_-_39203519 0.93 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr1_-_177134024 0.93 ENST00000367654.3
ASTN1
astrotactin 1
chr6_-_35656685 0.92 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr3_-_58563094 0.87 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr6_-_35656712 0.86 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chr19_-_6433765 0.75 ENST00000321510.6
SLC25A41
solute carrier family 25, member 41
chr16_-_755819 0.73 ENST00000397621.1
FBXL16
F-box and leucine-rich repeat protein 16
chr22_-_24622080 0.65 ENST00000425408.1
GGT5
gamma-glutamyltransferase 5
chr1_-_60392452 0.63 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr2_+_54951679 0.50 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr2_+_120189422 0.46 ENST00000306406.4
TMEM37
transmembrane protein 37
chr10_+_118350468 0.45 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr13_-_29069232 0.44 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr14_+_22739823 0.44 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr9_-_127263265 0.44 ENST00000373587.3
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr2_-_29297127 0.43 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr16_-_745946 0.43 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr19_-_8213753 0.42 ENST00000601739.1
FBN3
fibrillin 3
chr19_+_41509851 0.41 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr21_+_46066331 0.40 ENST00000334670.8
KRTAP10-11
keratin associated protein 10-11
chr17_-_39183452 0.40 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr1_+_16348366 0.40 ENST00000375692.1
ENST00000420078.1
CLCNKA
chloride channel, voltage-sensitive Ka
chr8_+_25042192 0.39 ENST00000410074.1
DOCK5
dedicator of cytokinesis 5
chr4_-_7105056 0.38 ENST00000504402.1
ENST00000499242.2
ENST00000501888.2
RP11-367J11.3
RP11-367J11.3
chr11_-_110582773 0.36 ENST00000524756.1
ARHGAP20
Rho GTPase activating protein 20
chr16_-_31100284 0.36 ENST00000280606.6
PRSS53
protease, serine, 53
chr21_+_46020497 0.36 ENST00000380102.2
KRTAP10-7
keratin associated protein 10-7
chr10_+_118350522 0.36 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr14_-_65409502 0.35 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr21_-_46012386 0.34 ENST00000400368.1
KRTAP10-6
keratin associated protein 10-6
chr8_+_85097110 0.34 ENST00000517638.1
ENST00000522647.1
RALYL
RALY RNA binding protein-like
chr2_-_46769694 0.34 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr11_-_59612969 0.34 ENST00000541311.1
ENST00000257248.2
GIF
gastric intrinsic factor (vitamin B synthesis)
chr1_+_1567474 0.33 ENST00000356026.5
MMP23B
matrix metallopeptidase 23B
chr1_+_16370271 0.32 ENST00000375679.4
CLCNKB
chloride channel, voltage-sensitive Kb
chr1_+_1567546 0.32 ENST00000378675.3
MMP23B
matrix metallopeptidase 23B
chr17_-_39216344 0.31 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr7_-_37026108 0.31 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr20_+_31619454 0.31 ENST00000349552.1
BPIFB6
BPI fold containing family B, member 6
chr19_+_13135731 0.31 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_16348497 0.30 ENST00000439316.2
CLCNKA
chloride channel, voltage-sensitive Ka
chr17_+_60704762 0.29 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr14_-_65409438 0.29 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr1_-_211307315 0.29 ENST00000271751.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr4_-_66535653 0.28 ENST00000354839.4
ENST00000432638.2
EPHA5
EPH receptor A5
chr15_-_71407833 0.27 ENST00000449977.2
CT62
cancer/testis antigen 62
chr1_-_1711508 0.27 ENST00000378625.1
NADK
NAD kinase
chr15_-_71407806 0.27 ENST00000566432.1
ENST00000567117.1
CT62
cancer/testis antigen 62
chrX_+_71354000 0.26 ENST00000510661.1
ENST00000535692.1
NHSL2
NHS-like 2
chr6_+_44187242 0.25 ENST00000393844.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr2_+_105050794 0.25 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr14_+_57735614 0.24 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr5_+_140514782 0.24 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr4_-_66536196 0.24 ENST00000511294.1
EPHA5
EPH receptor A5
chr21_+_45148735 0.24 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr16_+_23194033 0.24 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chrX_-_129299847 0.23 ENST00000319908.3
ENST00000287295.3
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr9_-_16870704 0.23 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chrX_+_68835911 0.23 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr19_+_45409011 0.22 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr21_+_46117087 0.22 ENST00000400365.3
KRTAP10-12
keratin associated protein 10-12
chr2_-_74780176 0.22 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr17_-_39197699 0.22 ENST00000306271.4
KRTAP1-1
keratin associated protein 1-1
chr4_-_109090106 0.21 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr1_-_244615425 0.21 ENST00000366535.3
ADSS
adenylosuccinate synthase
chrX_-_129299638 0.21 ENST00000535724.1
ENST00000346424.2
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr3_+_71803201 0.21 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr19_+_13135790 0.21 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_+_150264365 0.20 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr4_-_109089573 0.20 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr13_+_102104952 0.20 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chrX_-_78622805 0.19 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr1_+_207038699 0.18 ENST00000367098.1
IL20
interleukin 20
chr10_-_81708854 0.18 ENST00000372292.3
SFTPD
surfactant protein D
chr2_-_208989225 0.18 ENST00000264376.4
CRYGD
crystallin, gamma D
chr4_-_175750364 0.18 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr17_-_3796334 0.17 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr21_+_45209394 0.17 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr13_-_100624012 0.17 ENST00000267294.4
ZIC5
Zic family member 5
chr1_+_207039154 0.17 ENST00000367096.3
ENST00000391930.2
IL20
interleukin 20
chr19_-_2740036 0.17 ENST00000586572.1
ENST00000269740.4
AC006538.4
SLC39A3
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chrX_+_70364667 0.16 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr4_-_66536057 0.16 ENST00000273854.3
EPHA5
EPH receptor A5
chr1_+_46668994 0.16 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr6_-_34216766 0.16 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
C6orf1
chromosome 6 open reading frame 1
chrX_+_24711997 0.16 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr1_-_111991908 0.16 ENST00000235090.5
WDR77
WD repeat domain 77
chr18_+_76829441 0.15 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr15_+_80351910 0.15 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr21_+_31768348 0.15 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr19_-_3028354 0.14 ENST00000586422.1
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr2_-_74779744 0.14 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr3_-_53080047 0.13 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr10_+_49917751 0.13 ENST00000325239.5
ENST00000413659.2
WDFY4
WDFY family member 4
chr11_-_57417405 0.13 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr21_-_39870339 0.13 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr15_+_41245160 0.13 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr14_+_38677123 0.13 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr1_+_22963158 0.13 ENST00000438241.1
C1QA
complement component 1, q subcomponent, A chain
chr17_-_39191107 0.13 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr11_-_62689046 0.13 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chr20_+_61924532 0.12 ENST00000358894.6
ENST00000326996.6
ENST00000435874.1
COL20A1
collagen, type XX, alpha 1
chr19_+_35940486 0.12 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr15_+_73976715 0.12 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chr17_-_3794021 0.12 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr8_-_120685608 0.12 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr18_-_52989217 0.12 ENST00000570287.2
TCF4
transcription factor 4
chr1_+_18958008 0.12 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr9_-_35103105 0.12 ENST00000452248.2
ENST00000356493.5
STOML2
stomatin (EPB72)-like 2
chr3_-_45838011 0.12 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr12_-_11002063 0.12 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr21_-_31864275 0.12 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr16_+_838614 0.12 ENST00000262315.9
ENST00000455171.2
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr11_-_46142505 0.11 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr19_-_14586125 0.11 ENST00000292513.3
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr6_-_117086873 0.11 ENST00000368557.4
FAM162B
family with sequence similarity 162, member B
chr3_+_14444063 0.11 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr2_+_90248739 0.11 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr17_-_43045439 0.11 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr16_-_11485922 0.11 ENST00000599216.1
CTD-3088G3.8
Protein LOC388210
chr22_-_23922448 0.11 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr3_+_126243126 0.10 ENST00000319340.2
CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr11_+_66824346 0.10 ENST00000532559.1
RHOD
ras homolog family member D
chr2_+_89184868 0.10 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr22_-_23922410 0.10 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr21_+_18811205 0.09 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chrX_+_53078273 0.09 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr22_+_21369316 0.09 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chrX_+_72064876 0.09 ENST00000373532.3
ENST00000333826.5
DMRTC1B
DMRT-like family C1B
chr18_+_76829385 0.09 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr1_+_22962948 0.09 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr7_+_39017504 0.09 ENST00000403058.1
POU6F2
POU class 6 homeobox 2
chr22_+_29702572 0.09 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr1_-_71513471 0.09 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3
prostaglandin E receptor 3 (subtype EP3)
chr11_+_67777751 0.09 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chrX_-_153979315 0.09 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr13_+_30510003 0.09 ENST00000400540.1
LINC00544
long intergenic non-protein coding RNA 544
chr4_-_89444883 0.09 ENST00000273968.4
PYURF
PIGY upstream reading frame
chr4_-_47839966 0.09 ENST00000273857.4
ENST00000505909.1
ENST00000502252.1
CORIN
corin, serine peptidase
chr12_-_27091183 0.09 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN
asunder spermatogenesis regulator
chr1_+_61869748 0.08 ENST00000357977.5
NFIA
nuclear factor I/A
chr3_-_45837959 0.08 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr7_-_4877677 0.08 ENST00000538469.1
RADIL
Ras association and DIL domains
chrX_+_72064690 0.08 ENST00000438696.1
DMRTC1B
DMRT-like family C1B
chr14_-_50999190 0.07 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr19_+_54024251 0.07 ENST00000253144.9
ZNF331
zinc finger protein 331
chr2_+_234668894 0.07 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_-_98280383 0.07 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr15_+_81589254 0.07 ENST00000394652.2
IL16
interleukin 16
chrX_+_13707235 0.07 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr9_-_112260531 0.06 ENST00000374541.2
ENST00000262539.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr6_+_41755389 0.06 ENST00000398884.3
ENST00000398881.3
TOMM6
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr3_-_79816965 0.06 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_2739992 0.06 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr5_+_167181917 0.06 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr4_-_40632605 0.06 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr10_-_36813162 0.06 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr9_+_35792151 0.06 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr14_+_23340822 0.06 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr9_+_132934835 0.05 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr17_-_53809473 0.05 ENST00000575734.1
TMEM100
transmembrane protein 100
chr6_+_31540056 0.05 ENST00000418386.2
LTA
lymphotoxin alpha
chr6_+_31949801 0.05 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr2_+_46769798 0.05 ENST00000238738.4
RHOQ
ras homolog family member Q
chr6_-_168476511 0.04 ENST00000440994.2
FRMD1
FERM domain containing 1
chrY_+_4868267 0.04 ENST00000333703.4
PCDH11Y
protocadherin 11 Y-linked
chr3_+_141105705 0.04 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_-_121993673 0.04 ENST00000379692.4
NDNF
neuron-derived neurotrophic factor
chr9_+_124329336 0.04 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr17_-_76274572 0.04 ENST00000374945.1
RP11-219G17.4
RP11-219G17.4
chr3_-_50329835 0.04 ENST00000429673.2
IFRD2
interferon-related developmental regulator 2
chr19_-_16582754 0.04 ENST00000602151.1
ENST00000597937.1
ENST00000535753.2
EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
chr5_-_126409159 0.04 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr17_+_18280976 0.04 ENST00000399134.4
EVPLL
envoplakin-like
chrX_+_52926322 0.04 ENST00000430150.2
ENST00000452021.2
ENST00000412319.1
FAM156B
family with sequence similarity 156, member B
chr22_+_41956767 0.04 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr3_+_32859510 0.04 ENST00000383763.5
TRIM71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr19_+_10563567 0.04 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr10_-_101945771 0.04 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr12_-_15038779 0.03 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr16_+_28858004 0.03 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr1_-_111991850 0.03 ENST00000411751.2
WDR77
WD repeat domain 77
chr7_-_102789629 0.03 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr15_+_85523671 0.03 ENST00000310298.4
ENST00000557957.1
PDE8A
phosphodiesterase 8A
chr1_+_111992064 0.03 ENST00000483994.1
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr10_-_49701686 0.03 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr5_-_76935513 0.03 ENST00000306422.3
OTP
orthopedia homeobox
chr22_+_44319648 0.03 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr22_+_44319619 0.03 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr15_+_77712993 0.03 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr1_+_89990431 0.03 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr2_-_27938593 0.02 ENST00000379677.2
AC074091.13
Uncharacterized protein
chr11_-_74022658 0.02 ENST00000427714.2
ENST00000331597.4
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr7_-_107880508 0.02 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr7_+_29874341 0.02 ENST00000409290.1
ENST00000242140.5
WIPF3
WAS/WASL interacting protein family, member 3
chr17_-_18945798 0.02 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr1_-_89641680 0.02 ENST00000294671.2
GBP7
guanylate binding protein 7
chr2_-_89399845 0.02 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr2_+_169926047 0.02 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.6 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.4 GO:0007538 primary sex determination(GO:0007538)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.2 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:1904044 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.0 0.8 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 1.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 1.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 1.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.4 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 3.0 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 2.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.2 GO:0034709 methylosome(GO:0034709)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 1.0 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling