Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for ZIC2_GLI1

Z-value: 0.71

Motif logo

logo of logo of

Transcription factors associated with ZIC2_GLI1

Gene Symbol Gene ID Gene Info
ZIC2
ENSG00000043355.6 Zic family member 2
GLI1
ENSG00000111087.5 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI1hg19_v2_chr12_+_57853918_57853934,
hg19_v2_chr12_+_57857475_57857475		-0.365.0e-02Click!
ZIC2hg19_v2_chr13_+_100634004_100634026-0.048.4e-01Click!

Activity profile of ZIC2_GLI1 motif

Sorted Z-values of ZIC2_GLI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_163148973 4.15 ENST00000366888.2
PACRG
PARK2 co-regulated
chr9_-_34397800 3.34 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr22_-_50970506 2.31 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chrX_+_152240819 2.09 ENST00000421798.3
ENST00000535416.1
PNMA6C
PNMA6A
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr9_+_131218698 1.83 ENST00000434106.3
ENST00000546203.1
ENST00000446274.1
ENST00000421776.2
ENST00000432065.2
ODF2
outer dense fiber of sperm tails 2
chr22_-_50970566 1.74 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr1_+_47264711 1.65 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1
chr6_-_29595779 1.59 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr15_-_93616892 1.53 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
RGMA
repulsive guidance molecule family member a
chr22_-_50970919 1.47 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr9_+_131219179 1.46 ENST00000372791.3
ODF2
outer dense fiber of sperm tails 2
chr9_+_131218408 1.45 ENST00000351030.3
ENST00000604420.1
ENST00000535026.1
ENST00000448249.3
ENST00000393527.3
ODF2
outer dense fiber of sperm tails 2
chr16_+_75256507 1.34 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr15_-_78526855 1.34 ENST00000541759.1
ENST00000558130.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr2_-_28113965 1.32 ENST00000302188.3
RBKS
ribokinase
chr9_+_131218336 1.14 ENST00000372814.3
ODF2
outer dense fiber of sperm tails 2
chr12_-_25801478 1.08 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr20_+_57430162 0.95 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS
GNAS complex locus
chr3_-_52486841 0.90 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr11_-_75379612 0.86 ENST00000526740.1
MAP6
microtubule-associated protein 6
chr17_+_17876127 0.70 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr11_-_111783919 0.67 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr3_+_113616317 0.67 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr2_-_213403565 0.66 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr1_-_217250231 0.64 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr2_+_149402553 0.63 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr16_-_16317321 0.63 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr7_+_69064300 0.62 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr2_+_97481974 0.60 ENST00000377060.3
ENST00000305510.3
CNNM3
cyclin M3
chr7_-_112726393 0.60 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chr17_+_7608511 0.58 ENST00000226091.2
EFNB3
ephrin-B3
chr7_+_48211048 0.56 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr3_+_49449636 0.52 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr12_-_122985067 0.52 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr12_-_45270151 0.51 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr17_+_40834580 0.51 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr6_-_55739542 0.49 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr17_-_26989136 0.49 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr16_+_2521500 0.49 ENST00000293973.1
NTN3
netrin 3
chr12_-_122985494 0.49 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr16_-_1031259 0.47 ENST00000563837.1
ENST00000563863.1
ENST00000565069.1
ENST00000570014.1
RP11-161M6.2
LMF1
RP11-161M6.2
lipase maturation factor 1
chr4_-_5021164 0.45 ENST00000506508.1
ENST00000509419.1
ENST00000307746.4
CYTL1
cytokine-like 1
chr16_+_88493879 0.45 ENST00000565624.1
ENST00000437464.1
ZNF469
zinc finger protein 469
chr14_-_61124977 0.44 ENST00000554986.1
SIX1
SIX homeobox 1
chr6_+_33172407 0.44 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr15_-_78526942 0.43 ENST00000258873.4
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr12_-_45270077 0.43 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr11_+_45868957 0.40 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr17_-_74533734 0.40 ENST00000589342.1
CYGB
cytoglobin
chr1_+_32674675 0.39 ENST00000409358.1
DCDC2B
doublecortin domain containing 2B
chr10_-_95360983 0.38 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr8_-_17555164 0.38 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr14_+_24583836 0.38 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11
DDB1 and CUL4 associated factor 11
chr2_-_46769694 0.38 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr14_-_64971288 0.36 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr16_+_30675654 0.36 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr7_-_105517021 0.35 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr12_-_6798616 0.35 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
ZNF384
zinc finger protein 384
chr9_-_73483958 0.34 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr12_-_6798410 0.33 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
ZNF384
zinc finger protein 384
chr7_+_119913688 0.33 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr1_-_151798546 0.33 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr12_-_6798523 0.33 ENST00000319770.3
ZNF384
zinc finger protein 384
chr7_-_99679324 0.32 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr14_+_24584508 0.32 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11
DDB1 and CUL4 associated factor 11
chr7_+_116312411 0.31 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr1_-_112046289 0.31 ENST00000241356.4
ADORA3
adenosine A3 receptor
chr1_+_36690011 0.30 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
THRAP3
thyroid hormone receptor associated protein 3
chr17_-_74533963 0.30 ENST00000293230.5
CYGB
cytoglobin
chr20_-_30310656 0.29 ENST00000376055.4
BCL2L1
BCL2-like 1
chr15_+_60296421 0.29 ENST00000396057.4
FOXB1
forkhead box B1
chr3_+_4535025 0.28 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr1_+_152943122 0.28 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr9_+_22446814 0.28 ENST00000325870.2
DMRTA1
DMRT-like family A1
chr6_+_31620191 0.28 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chr6_+_26240561 0.28 ENST00000377745.2
HIST1H4F
histone cluster 1, H4f
chr17_+_43239231 0.27 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr20_+_36149602 0.27 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr9_-_130639997 0.27 ENST00000373176.1
AK1
adenylate kinase 1
chr4_-_186697044 0.27 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr3_+_153839149 0.26 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr3_-_8686479 0.26 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr7_+_149412094 0.26 ENST00000255992.10
ENST00000319551.8
KRBA1
KRAB-A domain containing 1
chr2_+_217498105 0.26 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr1_+_162531294 0.25 ENST00000367926.4
ENST00000271469.3
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr17_-_15496722 0.25 ENST00000472534.1
CDRT1
CMT1A duplicated region transcript 1
chr1_-_205782304 0.25 ENST00000367137.3
SLC41A1
solute carrier family 41 (magnesium transporter), member 1
chr7_+_31009148 0.25 ENST00000409904.3
ENST00000409316.1
GHRHR
growth hormone releasing hormone receptor
chr3_+_4535155 0.25 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr20_-_30310693 0.25 ENST00000307677.4
ENST00000420653.1
BCL2L1
BCL2-like 1
chr11_-_111784005 0.25 ENST00000527899.1
CRYAB
crystallin, alpha B
chr2_+_178977143 0.24 ENST00000286070.5
RBM45
RNA binding motif protein 45
chr1_+_164528866 0.24 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr2_-_133427767 0.23 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr4_-_186696425 0.23 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr20_+_32782375 0.23 ENST00000568305.1
ASIP
agouti signaling protein
chr5_+_102455968 0.22 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr7_+_138145145 0.21 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr5_+_52776449 0.21 ENST00000396947.3
FST
follistatin
chr6_-_43337180 0.21 ENST00000318149.3
ENST00000361428.2
ZNF318
zinc finger protein 318
chr6_-_134373732 0.21 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr2_+_26915584 0.21 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr7_-_105516923 0.21 ENST00000478915.1
ATXN7L1
ataxin 7-like 1
chr21_-_27945562 0.21 ENST00000299340.4
ENST00000435845.2
CYYR1
cysteine/tyrosine-rich 1
chr19_+_4198072 0.20 ENST00000262970.5
ANKRD24
ankyrin repeat domain 24
chr9_-_86571628 0.20 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr22_-_30783356 0.20 ENST00000382363.3
RNF215
ring finger protein 215
chr5_-_44388899 0.20 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr11_+_10477733 0.20 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr3_+_133118839 0.19 ENST00000302334.2
BFSP2
beaded filament structural protein 2, phakinin
chr7_-_91875109 0.19 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1
KRIT1, ankyrin repeat containing
chr22_-_46373004 0.19 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr11_-_111782696 0.18 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr6_-_29600832 0.18 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_-_183387723 0.18 ENST00000287713.6
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr22_-_30783075 0.18 ENST00000215798.6
RNF215
ring finger protein 215
chr16_+_29819096 0.17 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr10_+_24755416 0.17 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr11_-_11643540 0.17 ENST00000227756.4
GALNT18
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
chr19_+_45312347 0.16 ENST00000270233.6
ENST00000591520.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr19_+_36208877 0.16 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr2_+_137523086 0.16 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr19_-_55881741 0.15 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr2_+_106361333 0.15 ENST00000233154.4
ENST00000451463.2
NCK2
NCK adaptor protein 2
chr5_+_71403061 0.15 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr12_+_117176113 0.15 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chr5_-_76935513 0.15 ENST00000306422.3
OTP
orthopedia homeobox
chrX_+_70443050 0.15 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr11_-_30607819 0.15 ENST00000448418.2
MPPED2
metallophosphoesterase domain containing 2
chr7_+_114562616 0.15 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr12_+_122516626 0.15 ENST00000319080.7
MLXIP
MLX interacting protein
chr17_+_6926339 0.15 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr5_+_52776228 0.15 ENST00000256759.3
FST
follistatin
chr19_+_3708376 0.14 ENST00000539908.2
TJP3
tight junction protein 3
chr9_-_98279241 0.14 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr20_-_34025999 0.14 ENST00000374369.3
GDF5
growth differentiation factor 5
chr11_-_34938039 0.14 ENST00000395787.3
APIP
APAF1 interacting protein
chr14_+_96968802 0.14 ENST00000556619.1
ENST00000392990.2
PAPOLA
poly(A) polymerase alpha
chr1_+_226736446 0.14 ENST00000366788.3
ENST00000366789.4
C1orf95
chromosome 1 open reading frame 95
chr1_+_154966058 0.14 ENST00000392487.1
LENEP
lens epithelial protein
chr11_-_30608413 0.14 ENST00000528686.1
MPPED2
metallophosphoesterase domain containing 2
chr17_-_7137582 0.14 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr16_+_29818857 0.13 ENST00000567444.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_+_67088974 0.13 ENST00000513234.1
ENST00000504068.1
ENST00000515227.1
RP11-434D9.1
RP11-434D9.1
chr11_-_111783595 0.13 ENST00000528628.1
CRYAB
crystallin, alpha B
chr11_-_64527425 0.13 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr17_-_42298201 0.13 ENST00000527034.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr4_+_72052964 0.12 ENST00000264485.5
ENST00000425175.1
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr1_+_42846443 0.12 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chrX_-_107334790 0.12 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr16_+_29819372 0.12 ENST00000568544.1
ENST00000569978.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_+_4969116 0.12 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
KDM4B
lysine (K)-specific demethylase 4B
chr12_-_57522813 0.12 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr17_+_73997419 0.12 ENST00000425876.2
CDK3
cyclin-dependent kinase 3
chr9_+_109625378 0.11 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr20_+_43343886 0.11 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr16_+_29819446 0.11 ENST00000568282.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_+_31477250 0.11 ENST00000313737.4
AC024940.1
AC024940.1
chr1_-_150208320 0.11 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr9_-_115818951 0.11 ENST00000553380.1
ENST00000374227.3
ZFP37
ZFP37 zinc finger protein
chr11_-_119991589 0.11 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr2_-_178257401 0.11 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr4_-_38666430 0.11 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr13_+_111767650 0.11 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr9_-_98079965 0.10 ENST00000289081.3
FANCC
Fanconi anemia, complementation group C
chr4_-_134070250 0.10 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
RP11-9G1.3
chr5_+_161275320 0.10 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_-_40105617 0.10 ENST00000372852.3
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr15_-_75743915 0.10 ENST00000394949.4
SIN3A
SIN3 transcription regulator family member A
chr3_+_6902794 0.10 ENST00000357716.4
ENST00000486284.1
ENST00000389336.4
ENST00000403881.1
ENST00000402647.2
GRM7
glutamate receptor, metabotropic 7
chr11_-_34937858 0.10 ENST00000278359.5
APIP
APAF1 interacting protein
chr6_-_33160231 0.09 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr11_+_64009072 0.09 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr2_+_159825143 0.09 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr11_-_111782484 0.09 ENST00000533971.1
CRYAB
crystallin, alpha B
chr12_-_49333446 0.09 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr11_-_46142615 0.09 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr7_-_150777874 0.09 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr10_+_99344071 0.08 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr8_+_75736761 0.08 ENST00000260113.2
PI15
peptidase inhibitor 15
chr20_+_43343517 0.08 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chrX_-_107334750 0.08 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr2_-_193059634 0.08 ENST00000392314.1
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_-_115053781 0.08 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr1_+_44679159 0.07 ENST00000315913.5
ENST00000372289.2
DMAP1
DNA methyltransferase 1 associated protein 1
chr6_+_43968306 0.07 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr11_+_33278811 0.07 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr16_-_68002456 0.07 ENST00000576616.1
ENST00000572037.1
ENST00000338335.3
ENST00000422611.2
ENST00000316341.3
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr1_+_44679113 0.07 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1
DNA methyltransferase 1 associated protein 1
chr8_-_22014339 0.07 ENST00000306317.2
LGI3
leucine-rich repeat LGI family, member 3
chr14_-_30396802 0.07 ENST00000415220.2
PRKD1
protein kinase D1
chr10_-_86001210 0.07 ENST00000372105.3
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr15_+_81591757 0.07 ENST00000558332.1
IL16
interleukin 16
chr14_-_70655684 0.07 ENST00000356921.2
ENST00000381269.2
ENST00000357887.3
SLC8A3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr5_-_168727786 0.07 ENST00000332966.8
SLIT3
slit homolog 3 (Drosophila)
chrX_-_107979616 0.07 ENST00000372129.2
IRS4
insulin receptor substrate 4
chr2_-_25016251 0.07 ENST00000328379.5
PTRHD1
peptidyl-tRNA hydrolase domain containing 1
chr19_+_36602104 0.07 ENST00000585332.1
ENST00000262637.4
OVOL3
ovo-like zinc finger 3
chr12_-_4554780 0.06 ENST00000228837.2
FGF6
fibroblast growth factor 6
chr6_-_32784687 0.06 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC2_GLI1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.2 1.7 GO:0018879 biphenyl metabolic process(GO:0018879)
0.2 0.9 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.2 0.7 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.2 0.6 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 0.5 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.7 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.4 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.5 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.2 GO:0072061 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.1 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 10.0 GO:0007286 spermatid development(GO:0007286)
0.1 1.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.5 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.0 1.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.3 GO:0060179 male mating behavior(GO:0060179)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:1901675 response to methylglyoxal(GO:0051595) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0070269 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.0 0.4 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 5.9 GO:0001520 outer dense fiber(GO:0001520)
0.2 4.1 GO:0097225 sperm midpiece(GO:0097225)
0.2 0.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0033010 paranodal junction(GO:0033010)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.7 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 4.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0070404 NADH binding(GO:0070404)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.9 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.4 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling