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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZKSCAN1

Z-value: 0.85

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Transcription factors associated with ZKSCAN1

Gene Symbol Gene ID Gene Info
ZKSCAN1
ENSG00000106261.12 zinc finger with KRAB and SCAN domains 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZKSCAN1hg19_v2_chr7_+_99613195_99613206-0.587.6e-04Click!

Activity profile of ZKSCAN1 motif

Sorted Z-values of ZKSCAN1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_135394840 5.65 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr12_+_4385230 5.55 ENST00000536537.1
CCND2
cyclin D2
chr22_-_37640456 5.23 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_37640277 4.95 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr11_-_58343319 3.73 ENST00000395074.2
LPXN
leupaxin
chr1_-_205391178 3.28 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr9_+_126131131 3.19 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr19_-_19051993 3.01 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr12_-_25055177 2.72 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr11_-_568369 2.48 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG
MIR210 host gene (non-protein coding)
chr1_+_209859510 2.29 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_-_123639445 2.24 ENST00000312189.6
PHF19
PHD finger protein 19
chr1_-_149908217 2.07 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr9_+_103189660 1.91 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr9_-_123639600 1.90 ENST00000373896.3
PHF19
PHD finger protein 19
chr5_-_127873659 1.83 ENST00000262464.4
FBN2
fibrillin 2
chr19_-_55660561 1.82 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr9_+_103189536 1.70 ENST00000374885.1
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr1_+_65613340 1.55 ENST00000546702.1
AK4
adenylate kinase 4
chr1_+_16083154 1.54 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chrX_+_47441712 1.46 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr20_-_56265680 1.44 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr22_+_33197683 1.37 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr20_-_48770244 1.34 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189
transmembrane protein 189
chr2_+_74120094 1.27 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2
actin, gamma 2, smooth muscle, enteric
chr16_-_19729502 1.27 ENST00000219837.7
KNOP1
lysine-rich nucleolar protein 1
chr11_+_72975559 1.16 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_72975524 1.15 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_72975578 1.12 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr5_+_149980622 1.02 ENST00000394243.1
SYNPO
synaptopodin
chr1_+_65613217 0.99 ENST00000545314.1
AK4
adenylate kinase 4
chr10_-_76859247 0.97 ENST00000472493.2
ENST00000605915.1
ENST00000478873.2
DUSP13
dual specificity phosphatase 13
chr2_-_158345462 0.92 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr3_+_12329397 0.90 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr3_+_12329358 0.85 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr22_+_20861858 0.85 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr14_-_96743060 0.81 ENST00000554299.1
DKFZP434O1614
DKFZP434O1614
chr20_+_43343476 0.80 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr19_+_39138271 0.79 ENST00000252699.2
ACTN4
actinin, alpha 4
chr17_-_73150599 0.78 ENST00000392566.2
ENST00000581874.1
HN1
hematological and neurological expressed 1
chr5_-_131562935 0.78 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr20_+_4152356 0.74 ENST00000379460.2
SMOX
spermine oxidase
chr1_-_155224751 0.73 ENST00000350210.2
ENST00000368368.3
FAM189B
family with sequence similarity 189, member B
chr8_-_131028869 0.68 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr19_+_850985 0.68 ENST00000590230.1
ELANE
elastase, neutrophil expressed
chr15_-_34635314 0.66 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr5_-_172756506 0.66 ENST00000265087.4
STC2
stanniocalcin 2
chr20_+_43343517 0.64 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr7_+_73588575 0.63 ENST00000265753.8
EIF4H
eukaryotic translation initiation factor 4H
chr2_+_27070964 0.63 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr19_-_344786 0.62 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr10_+_89420706 0.61 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr7_+_73588665 0.60 ENST00000353999.6
EIF4H
eukaryotic translation initiation factor 4H
chr12_-_123450986 0.59 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr14_+_103851712 0.58 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr17_-_46716647 0.57 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr17_+_75372165 0.56 ENST00000427674.2
SEPT9
septin 9
chr15_+_89921280 0.54 ENST00000560596.1
ENST00000558692.1
ENST00000538734.2
ENST00000559235.1
LINC00925
long intergenic non-protein coding RNA 925
chr11_-_118134997 0.54 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr15_+_75498739 0.53 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr1_+_113009163 0.53 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr16_-_838329 0.53 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RPUSD1
RNA pseudouridylate synthase domain containing 1
chr12_+_8995832 0.52 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr2_+_27071045 0.50 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr11_+_33563821 0.49 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr6_+_36922209 0.48 ENST00000373674.3
PI16
peptidase inhibitor 16
chr18_+_52495426 0.45 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr11_+_70049269 0.45 ENST00000301838.4
FADD
Fas (TNFRSF6)-associated via death domain
chr16_+_67562702 0.44 ENST00000379312.3
ENST00000042381.4
ENST00000540839.3
FAM65A
family with sequence similarity 65, member A
chr22_+_21921994 0.43 ENST00000545681.1
UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr10_-_126432821 0.41 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chr19_+_13051206 0.40 ENST00000586760.1
CALR
calreticulin
chr19_+_39138320 0.39 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chr6_-_30640811 0.36 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr12_+_122326630 0.35 ENST00000541212.1
ENST00000340175.5
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr1_+_16348366 0.34 ENST00000375692.1
ENST00000420078.1
CLCNKA
chloride channel, voltage-sensitive Ka
chr9_+_132934835 0.33 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chrX_-_15402498 0.32 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr11_+_64808675 0.31 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr19_-_15918936 0.31 ENST00000334920.2
OR10H1
olfactory receptor, family 10, subfamily H, member 1
chr3_-_64673289 0.31 ENST00000295903.4
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_+_87563557 0.30 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr7_+_72742178 0.30 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr7_-_72742085 0.29 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr15_-_80215984 0.29 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr9_-_86153218 0.28 ENST00000304195.3
ENST00000376438.1
FRMD3
FERM domain containing 3
chrX_-_130423200 0.28 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr12_+_122326662 0.28 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chrX_-_130423386 0.28 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1
chr1_+_32083301 0.28 ENST00000403528.2
HCRTR1
hypocretin (orexin) receptor 1
chr3_+_184081175 0.28 ENST00000452961.1
ENST00000296223.3
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr3_+_184081213 0.27 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr13_+_76445187 0.27 ENST00000318245.4
C13orf45
chromosome 13 open reading frame 45
chr7_+_72742162 0.27 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr16_+_56899114 0.27 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3
solute carrier family 12 (sodium/chloride transporter), member 3
chr4_+_39460620 0.26 ENST00000340169.2
ENST00000261434.3
LIAS
lipoic acid synthetase
chr1_+_226411319 0.25 ENST00000542034.1
ENST00000366810.5
MIXL1
Mix paired-like homeobox
chr11_-_73720276 0.25 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr6_+_35265586 0.25 ENST00000542066.1
ENST00000316637.5
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chrX_+_150866779 0.24 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr17_-_73150629 0.23 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr2_-_37193606 0.23 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr19_-_38916839 0.23 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr14_-_76447336 0.22 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr5_-_134735568 0.22 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr12_+_52400719 0.20 ENST00000293662.4
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr11_+_46366918 0.20 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr5_+_137774706 0.19 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr15_-_49103184 0.19 ENST00000399334.3
ENST00000325747.5
CEP152
centrosomal protein 152kDa
chr6_-_43276535 0.18 ENST00000372569.3
ENST00000274990.4
CRIP3
cysteine-rich protein 3
chr11_-_61197480 0.18 ENST00000439958.3
ENST00000394888.4
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr4_+_39460659 0.17 ENST00000513731.1
LIAS
lipoic acid synthetase
chr5_+_155753745 0.17 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr8_+_22102626 0.17 ENST00000519237.1
ENST00000397802.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr19_+_18794470 0.16 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr11_-_64739542 0.16 ENST00000536065.1
C11orf85
chromosome 11 open reading frame 85
chr14_+_63671577 0.15 ENST00000555125.1
RHOJ
ras homolog family member J
chr19_-_38916822 0.15 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr19_+_3178736 0.14 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr4_+_39460689 0.14 ENST00000381846.1
LIAS
lipoic acid synthetase
chr16_-_11370330 0.14 ENST00000241808.4
ENST00000435245.2
PRM2
protamine 2
chr10_+_102222798 0.13 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chrX_-_130423240 0.12 ENST00000370910.1
ENST00000370901.4
IGSF1
immunoglobulin superfamily, member 1
chr17_-_26684473 0.10 ENST00000540200.1
POLDIP2
polymerase (DNA-directed), delta interacting protein 2
chr10_+_23384435 0.09 ENST00000376510.3
MSRB2
methionine sulfoxide reductase B2
chr20_-_3644046 0.09 ENST00000290417.2
ENST00000319242.3
GFRA4
GDNF family receptor alpha 4
chr21_+_46066331 0.08 ENST00000334670.8
KRTAP10-11
keratin associated protein 10-11
chr6_-_33160231 0.07 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr2_-_183387430 0.07 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr11_-_64739358 0.06 ENST00000301896.5
ENST00000530444.1
C11orf85
chromosome 11 open reading frame 85
chr9_+_138413277 0.06 ENST00000263598.2
ENST00000371781.3
LCN1
lipocalin 1
chr17_+_36858694 0.05 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr19_-_50666404 0.04 ENST00000600293.1
IZUMO2
IZUMO family member 2
chr20_+_36932521 0.04 ENST00000262865.4
BPI
bactericidal/permeability-increasing protein
chr3_+_184081137 0.04 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr10_-_88281494 0.03 ENST00000298767.5
WAPAL
wings apart-like homolog (Drosophila)
chr10_+_112679301 0.03 ENST00000265277.5
ENST00000369452.4
SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr7_+_87563458 0.02 ENST00000398204.4
ADAM22
ADAM metallopeptidase domain 22
chr2_+_113931513 0.02 ENST00000245796.6
ENST00000441564.3
PSD4
pleckstrin and Sec7 domain containing 4
chr4_-_176733897 0.02 ENST00000393658.2
GPM6A
glycoprotein M6A
chr2_+_1488435 0.02 ENST00000446278.1
ENST00000469607.1
TPO
thyroid peroxidase
chr2_+_231902193 0.02 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr1_-_36615065 0.01 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr19_-_50666431 0.01 ENST00000293405.3
IZUMO2
IZUMO family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.5 3.2 GO:0014028 notochord formation(GO:0014028)
0.5 3.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 2.7 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.4 1.7 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.4 1.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.3 4.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 1.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 1.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.3 3.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 1.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.3 2.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 5.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.7 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.6 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.2 1.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.5 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.1 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.7 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.6 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.1 3.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.7 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.7 GO:1903238 neutrophil mediated killing of gram-negative bacterium(GO:0070945) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 1.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 2.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.5 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 5.4 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.0 GO:0097444 spine apparatus(GO:0097444)
0.1 4.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 10.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.8 GO:0005861 troponin complex(GO:0005861)
0.1 1.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.7 GO:0002102 podosome(GO:0002102)
0.0 7.1 GO:0005604 basement membrane(GO:0005604)
0.0 1.3 GO:0032982 myosin filament(GO:0032982)
0.0 1.2 GO:0031143 pseudopodium(GO:0031143)
0.0 3.0 GO:0045178 basal part of cell(GO:0045178)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.5 GO:0042589 platelet dense granule membrane(GO:0031088) zymogen granule membrane(GO:0042589)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 5.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.6 3.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.5 2.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.5 2.7 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 1.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.2 0.7 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.2 0.6 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 1.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 3.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.7 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.6 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.8 GO:0031014 troponin T binding(GO:0031014)
0.1 0.7 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.8 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 2.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 0.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 5.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0016499 orexin receptor activity(GO:0016499)
0.1 1.5 GO:0031005 filamin binding(GO:0031005)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 4.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 9.0 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 1.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 5.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 5.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 5.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 3.1 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S