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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZKSCAN3

Z-value: 0.36

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Transcription factors associated with ZKSCAN3

Gene Symbol Gene ID Gene Info
ZKSCAN3
ENSG00000189298.9 zinc finger with KRAB and SCAN domains 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZKSCAN3hg19_v2_chr6_+_28317685_283177610.193.2e-01Click!

Activity profile of ZKSCAN3 motif

Sorted Z-values of ZKSCAN3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_3598871 1.68 ENST00000603362.1
ENST00000604479.1
TP73
tumor protein p73
chr9_+_124926856 1.14 ENST00000418632.1
MORN5
MORN repeat containing 5
chr15_-_41624685 1.14 ENST00000560640.1
ENST00000220514.3
OIP5
Opa interacting protein 5
chr15_+_41624892 0.93 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
NUSAP1
nucleolar and spindle associated protein 1
chr19_+_39786962 0.64 ENST00000333625.2
IFNL1
interferon, lambda 1
chr18_-_74728998 0.43 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr19_+_39759154 0.43 ENST00000331982.5
IFNL2
interferon, lambda 2
chr19_-_39735646 0.40 ENST00000413851.2
IFNL3
interferon, lambda 3
chr16_+_2479390 0.30 ENST00000397066.4
CCNF
cyclin F
chr14_-_106926724 0.28 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr7_+_155089486 0.28 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1
insulin induced gene 1
chr2_+_191745560 0.28 ENST00000338435.4
GLS
glutaminase
chr9_+_138235095 0.27 ENST00000320778.2
C9orf62
chromosome 9 open reading frame 62
chr5_+_65018017 0.24 ENST00000380985.5
ENST00000502464.1
NLN
neurolysin (metallopeptidase M3 family)
chr10_+_6779326 0.23 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr15_+_74610894 0.20 ENST00000558821.1
ENST00000268082.4
CCDC33
coiled-coil domain containing 33
chr14_-_80697396 0.20 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr10_+_21823079 0.19 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr7_+_155090271 0.19 ENST00000476756.1
INSIG1
insulin induced gene 1
chr14_-_106069247 0.17 ENST00000479229.1
RP11-731F5.1
RP11-731F5.1
chr11_-_64013288 0.15 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_-_155089251 0.15 ENST00000609974.1
AC144652.1
AC144652.1
chr19_-_42348692 0.14 ENST00000330743.3
ENST00000601246.1
LYPD4
LY6/PLAUR domain containing 4
chr10_+_21823243 0.14 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr22_+_50312316 0.14 ENST00000328268.4
CRELD2
cysteine-rich with EGF-like domains 2
chr22_-_50312052 0.13 ENST00000330817.6
ALG12
ALG12, alpha-1,6-mannosyltransferase
chrX_+_153775821 0.12 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr8_+_123793633 0.11 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr11_-_64013663 0.11 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr22_+_50312379 0.10 ENST00000407217.3
ENST00000403427.3
CRELD2
cysteine-rich with EGF-like domains 2
chr6_-_31508304 0.10 ENST00000376177.2
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr12_-_3982511 0.10 ENST00000427057.2
ENST00000228820.4
PARP11
poly (ADP-ribose) polymerase family, member 11
chr5_-_65017921 0.10 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr22_+_50312274 0.10 ENST00000404488.3
CRELD2
cysteine-rich with EGF-like domains 2
chr12_-_3982548 0.09 ENST00000397096.2
ENST00000447133.3
ENST00000450737.2
PARP11
poly (ADP-ribose) polymerase family, member 11
chr1_-_115259337 0.08 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_+_93913713 0.08 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chrX_-_135338503 0.08 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr16_-_745946 0.07 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chrX_-_153775426 0.07 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr19_-_49258606 0.06 ENST00000310160.3
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr1_+_93913665 0.06 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
FNBP1L
formin binding protein 1-like
chr3_-_122512619 0.06 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr1_-_28415075 0.06 ENST00000373863.3
ENST00000436342.2
ENST00000540618.1
ENST00000545175.1
EYA3
eyes absent homolog 3 (Drosophila)
chr12_+_109535373 0.06 ENST00000242576.2
UNG
uracil-DNA glycosylase
chr1_-_19811996 0.06 ENST00000264203.3
ENST00000401084.2
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr19_+_32836499 0.04 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr1_+_226250379 0.04 ENST00000366815.3
ENST00000366814.3
H3F3A
H3 histone, family 3A
chr1_-_19811962 0.03 ENST00000375142.1
ENST00000264202.6
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr5_+_140079919 0.03 ENST00000274712.3
ZMAT2
zinc finger, matrin-type 2
chr14_+_94492674 0.03 ENST00000203664.5
ENST00000553723.1
OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr12_+_100867694 0.03 ENST00000392986.3
ENST00000549996.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_-_95297534 0.02 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr1_-_28415204 0.02 ENST00000373871.3
EYA3
eyes absent homolog 3 (Drosophila)
chr5_-_114598548 0.01 ENST00000379615.3
ENST00000419445.1
PGGT1B
protein geranylgeranyltransferase type I, beta subunit
chr1_-_99470368 0.01 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr17_-_60142609 0.00 ENST00000397786.2
MED13
mediator complex subunit 13
chr12_+_109535923 0.00 ENST00000336865.2
UNG
uracil-DNA glycosylase

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.4 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.2 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 1.1 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.0 GO:0031055 chromatin remodeling at centromere(GO:0031055)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 1.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere