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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZNF282

Z-value: 0.35

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ENSG00000170265.7 zinc finger protein 282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF282hg19_v2_chr7_+_148892557_148892580-0.202.8e-01Click!

Activity profile of ZNF282 motif

Sorted Z-values of ZNF282 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_50970506 0.66 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr22_-_50970919 0.59 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B
chr9_+_126777676 0.56 ENST00000488674.2
LIM homeobox 2
chr12_-_13248598 0.43 ENST00000337630.6
ENST00000545699.1
germ cell associated 1
chr10_+_114135004 0.39 ENST00000393081.1
acyl-CoA synthetase long-chain family member 5
chr10_+_95753714 0.39 ENST00000260766.3
phospholipase C, epsilon 1
chr2_-_241497374 0.38 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ankyrin repeat and MYND domain containing 1
chr20_-_62284766 0.36 ENST00000370053.1
stathmin-like 3
chr22_-_24641027 0.33 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
gamma-glutamyltransferase 5
chr16_+_67927147 0.33 ENST00000291041.5
protein serine kinase H1
chr14_-_24911448 0.31 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
short chain dehydrogenase/reductase family 39U, member 1
chr6_-_79944336 0.31 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr17_-_56605341 0.31 ENST00000583114.1
septin 4
chr6_+_39760783 0.30 ENST00000398904.2
ENST00000538976.1
dishevelled associated activator of morphogenesis 2
chr7_+_139026057 0.28 ENST00000541515.3
LUC7-like 2 (S. cerevisiae)
chr12_-_49582978 0.28 ENST00000301071.7
tubulin, alpha 1a
chr16_+_29467780 0.27 ENST00000395400.3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr19_-_6110474 0.26 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
regulatory factor X, 2 (influences HLA class II expression)
chr16_+_30207122 0.26 ENST00000395137.2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr12_+_122150646 0.26 ENST00000449592.2
transmembrane protein 120B
chr1_-_45288932 0.25 ENST00000438067.1
patched 2
chr15_+_38276910 0.25 ENST00000558081.2
RP11-1008C21.1
chr22_+_27017921 0.24 ENST00000354760.3
crystallin, beta A4
chr1_-_9129631 0.23 ENST00000377414.3
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_13390765 0.23 ENST00000357367.2
PRAME family member 8
chr14_-_36989336 0.23 ENST00000522719.2
NK2 homeobox 1
chr7_+_139025875 0.23 ENST00000297534.6
chromosome 7 open reading frame 55
chr8_+_74888417 0.22 ENST00000517439.1
ENST00000312184.5
transmembrane protein 70
chr4_-_74904398 0.21 ENST00000296026.4
chemokine (C-X-C motif) ligand 3
chr17_+_55183261 0.21 ENST00000576295.1
A kinase (PRKA) anchor protein 1
chr22_-_50970566 0.20 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr16_-_70239683 0.19 ENST00000601706.1
Uncharacterized protein
chr17_-_73937116 0.18 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
Fas (TNFRSF6) binding factor 1
chr2_-_241497390 0.18 ENST00000272972.3
ENST00000401804.1
ENST00000361678.4
ENST00000405523.3
ankyrin repeat and MYND domain containing 1
chr14_+_55590646 0.17 ENST00000553493.1
lectin, galactoside-binding, soluble, 3
chrX_-_135849484 0.17 ENST00000370620.1
ENST00000535227.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_+_226250379 0.17 ENST00000366815.3
ENST00000366814.3
H3 histone, family 3A
chr6_+_10748019 0.17 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
synaptonemal complex protein 2-like
transmembrane protein 14B
chr19_-_58220517 0.16 ENST00000512439.2
ENST00000426889.1
zinc finger protein 154
chr6_+_10747986 0.16 ENST00000379542.5
transmembrane protein 14B
chr5_+_167718604 0.16 ENST00000265293.4
WW and C2 domain containing 1
chr14_-_36989427 0.15 ENST00000354822.5
NK2 homeobox 1
chr11_+_66278080 0.15 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
Bardet-Biedl syndrome 1
chr17_+_66509019 0.13 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr6_+_32938692 0.13 ENST00000443797.2
bromodomain containing 2
chr6_+_32938665 0.13 ENST00000374831.4
ENST00000395289.2
bromodomain containing 2
chr10_-_28034989 0.13 ENST00000375790.5
mohawk homeobox
chr12_-_113841678 0.13 ENST00000552280.1
ENST00000257549.4
serine dehydratase
chr3_-_180707466 0.12 ENST00000491873.1
ENST00000486355.1
ENST00000382564.2
DnaJ (Hsp40) homolog, subfamily C, member 19
chr11_+_111957497 0.11 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
succinate dehydrogenase complex, subunit D, integral membrane protein
chr1_+_45792541 0.11 ENST00000334815.3
4-hydroxyphenylpyruvate dioxygenase-like
chr11_+_63998006 0.10 ENST00000355040.4
DnaJ (Hsp40) homolog, subfamily C, member 4
chrX_-_49121165 0.10 ENST00000376207.4
ENST00000376199.2
forkhead box P3
chr1_+_17248418 0.10 ENST00000375541.5
ciliary rootlet coiled-coil, rootletin
chr12_-_127256772 0.10 ENST00000536517.1
long intergenic non-protein coding RNA 944
chr5_+_7869217 0.10 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr12_+_4758264 0.09 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr10_+_51572408 0.09 ENST00000374082.1
nuclear receptor coactivator 4
chr17_+_41323204 0.09 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
neighbor of BRCA1 gene 1
chr16_-_62070305 0.09 ENST00000584337.1
cadherin 8, type 2
chrX_-_13835147 0.08 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr21_+_35747773 0.08 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
small integral membrane protein 11
chr10_+_51572339 0.08 ENST00000344348.6
nuclear receptor coactivator 4
chr1_+_160313062 0.08 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
nicastrin
chr10_-_114206649 0.08 ENST00000369404.3
ENST00000369405.3
zinc finger, DHHC-type containing 6
chr11_-_321340 0.08 ENST00000526811.1
interferon induced transmembrane protein 3
chr7_-_155326532 0.08 ENST00000406197.1
ENST00000321736.5
canopy FGF signaling regulator 1
chr17_-_61996136 0.07 ENST00000342364.4
growth hormone 1
chr16_+_67204400 0.07 ENST00000563439.1
ENST00000432069.2
ENST00000564992.1
ENST00000564053.1
nucleolar protein 3 (apoptosis repressor with CARD domain)
chrX_-_72095622 0.07 ENST00000290273.5
DMRT-like family C1
chr15_-_44955842 0.07 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
spastic paraplegia 11 (autosomal recessive)
chr2_+_242289502 0.07 ENST00000451310.1
septin 2
chr11_-_111957451 0.07 ENST00000504148.2
ENST00000541231.1
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr6_-_17706618 0.07 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr14_+_58711539 0.07 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr12_-_122296755 0.07 ENST00000289004.4
4-hydroxyphenylpyruvate dioxygenase
chr1_+_145507587 0.07 ENST00000330165.8
ENST00000369307.3
RNA binding motif protein 8A
chr20_+_62492566 0.06 ENST00000369916.3
abhydrolase domain containing 16B
chr12_-_9102549 0.06 ENST00000000412.3
mannose-6-phosphate receptor (cation dependent)
chr17_+_42422662 0.06 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
granulin
chr19_-_46285736 0.06 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr2_-_197664366 0.05 ENST00000409364.3
ENST00000263956.3
general transcription factor IIIC, polypeptide 3, 102kDa
chr2_+_137523086 0.05 ENST00000409968.1
thrombospondin, type I, domain containing 7B
chrX_-_47004878 0.05 ENST00000377811.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr2_+_232260254 0.05 ENST00000287590.5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr5_-_7869108 0.05 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FAST kinase domains 3
chrX_-_13835461 0.05 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr17_-_77924627 0.05 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1 domain family, member 16
chr13_+_31309645 0.05 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chr15_-_83736091 0.05 ENST00000261721.4
BTB (POZ) domain containing 1
chrM_+_9207 0.04 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr1_-_108735440 0.04 ENST00000370041.4
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr12_+_54519842 0.04 ENST00000508564.1
RP11-834C11.4
chr19_+_30097181 0.04 ENST00000586420.1
ENST00000221770.3
ENST00000392279.3
ENST00000590688.1
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
chr1_-_160313025 0.04 ENST00000368069.3
ENST00000241704.7
coatomer protein complex, subunit alpha
chr3_-_170587974 0.04 ENST00000463836.1
ribosomal protein L22-like 1
chr17_+_42422637 0.04 ENST00000053867.3
ENST00000588143.1
granulin
chr12_-_46766577 0.04 ENST00000256689.5
solute carrier family 38, member 2
chr8_+_10383039 0.04 ENST00000328655.3
ENST00000522210.1
protease, serine, 55
chr3_-_186262166 0.04 ENST00000307944.5
crystallin, gamma S
chr5_-_175788758 0.04 ENST00000510164.1
ENST00000533553.1
ENST00000504688.1
ENST00000393725.2
ENST00000503082.1
ENST00000506983.1
KIAA1191
chr5_+_150816595 0.03 ENST00000520111.1
ENST00000520701.1
ENST00000429484.2
solute carrier family 36 (proton/amino acid symporter), member 1
chr19_-_39390350 0.03 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
sirtuin 2
chr19_+_39390587 0.03 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr1_+_40723779 0.03 ENST00000372759.3
zinc metallopeptidase STE24
chr6_+_10585979 0.02 ENST00000265012.4
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr20_-_43150601 0.02 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr6_-_137314371 0.02 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
chr19_-_51340469 0.02 ENST00000326856.4
kallikrein-related peptidase 15
chr1_-_2126192 0.02 ENST00000378546.4
chromosome 1 open reading frame 86
chr4_+_52709229 0.02 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCN1, defective in cullin neddylation 1, domain containing 4
chr8_-_21988558 0.02 ENST00000312841.8
hair growth associated
chr18_+_54318566 0.01 ENST00000589935.1
ENST00000357574.3
WD repeat domain 7
chr7_+_16828866 0.01 ENST00000597084.1
Uncharacterized protein
chr1_-_9129735 0.01 ENST00000377424.4
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr8_-_28347737 0.01 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
F-box protein 16
chr12_-_125473600 0.01 ENST00000308736.2
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr4_+_88343952 0.01 ENST00000440591.2
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr18_-_47018869 0.01 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr1_-_24151903 0.01 ENST00000436439.2
ENST00000374490.3
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr19_-_39390440 0.01 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
sirtuin 2
chr18_-_47018769 0.00 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr1_+_47799446 0.00 ENST00000371873.5
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr3_+_45927994 0.00 ENST00000357632.2
ENST00000395963.2
chemokine (C-C motif) receptor 9
chr4_+_39460659 0.00 ENST00000513731.1
lipoic acid synthetase
chr12_-_127256858 0.00 ENST00000542248.1
ENST00000540684.1
long intergenic non-protein coding RNA 944
chr18_-_47017956 0.00 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32 readthrough
ribosomal protein L17
chr1_-_24151892 0.00 ENST00000235958.4
3-hydroxymethyl-3-methylglutaryl-CoA lyase

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.6 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.0 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway