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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZNF350

Z-value: 0.55

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 zinc finger protein 350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_524901130.412.6e-02Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_132286754 3.45 ENST00000434330.1
CCDC74A
coiled-coil domain containing 74A
chr2_+_132287237 2.89 ENST00000467992.2
CCDC74A
coiled-coil domain containing 74A
chr1_-_46089718 2.32 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
CCDC17
coiled-coil domain containing 17
chr17_+_68071389 2.17 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_+_100328433 2.17 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr17_+_68071458 2.15 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr4_+_75858290 2.02 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr4_+_75858318 1.83 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr1_-_46089639 1.75 ENST00000445048.2
CCDC17
coiled-coil domain containing 17
chr1_-_98510843 1.47 ENST00000413670.2
ENST00000538428.1
MIR137HG
MIR137 host gene (non-protein coding)
chr16_+_69600209 1.36 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_+_68165657 1.26 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr20_+_62367989 1.25 ENST00000309546.3
LIME1
Lck interacting transmembrane adaptor 1
chr5_+_42423872 1.24 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr2_+_233497931 1.20 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr11_-_63381925 1.20 ENST00000415826.1
PLA2G16
phospholipase A2, group XVI
chr16_+_69600058 1.15 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_-_45687128 0.81 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr2_-_157198860 0.78 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_+_120301997 0.78 ENST00000602047.1
PCDP1
Primary ciliary dyskinesia protein 1
chr2_+_120302041 0.77 ENST00000442513.3
ENST00000413369.3
PCDP1
Primary ciliary dyskinesia protein 1
chr14_+_96671016 0.74 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr4_-_76008706 0.73 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
RP11-44F21.5
chr18_+_77155856 0.71 ENST00000253506.5
ENST00000591814.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr12_+_50451331 0.71 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr12_+_50451462 0.69 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr11_-_62473776 0.64 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr3_-_113775328 0.63 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
KIAA1407
chr13_-_96329048 0.63 ENST00000606011.1
ENST00000499499.2
DNAJC3-AS1
DNAJC3 antisense RNA 1 (head to head)
chr17_+_7487146 0.58 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr11_-_62473706 0.57 ENST00000403550.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_8954491 0.56 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16
chromosome 11 open reading frame 16
chr12_+_81471816 0.54 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr1_-_33647267 0.49 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr8_+_86157699 0.49 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr11_-_414948 0.48 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr11_-_63381823 0.45 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chr11_-_327537 0.43 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr4_+_6784401 0.41 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr3_-_11623804 0.40 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr6_-_56707943 0.40 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr10_-_12084770 0.39 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr16_+_71879861 0.37 ENST00000427980.2
ENST00000568581.1
ATXN1L
IST1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr3_+_140947563 0.35 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr18_+_77155942 0.34 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr12_+_131438443 0.34 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr10_+_69644404 0.34 ENST00000212015.6
SIRT1
sirtuin 1
chr11_-_119217365 0.32 ENST00000360167.4
ENST00000555262.1
ENST00000449574.2
ENST00000445041.2
MFRP
C1QTNF5
membrane frizzled-related protein
C1q and tumor necrosis factor related protein 5
chr16_+_14802801 0.32 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr17_+_6554971 0.32 ENST00000391428.2
C17orf100
chromosome 17 open reading frame 100
chr7_+_2559399 0.29 ENST00000222725.5
ENST00000359574.3
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_64323428 0.27 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr8_+_144295067 0.26 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr11_-_7041466 0.26 ENST00000536068.1
ENST00000278314.4
ZNF214
zinc finger protein 214
chr11_-_9113093 0.24 ENST00000450649.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr5_-_107717058 0.21 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr10_-_94003003 0.21 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr16_+_31225337 0.21 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr11_-_9113137 0.20 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr15_+_57210818 0.20 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr11_-_64612041 0.19 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr1_-_51425902 0.19 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr17_+_19030782 0.18 ENST00000344415.4
ENST00000577213.1
GRAPL
GRB2-related adaptor protein-like
chr6_-_28303901 0.18 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr12_-_53228079 0.17 ENST00000330553.5
KRT79
keratin 79
chr14_+_73603126 0.17 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
PSEN1
presenilin 1
chr19_+_42829702 0.17 ENST00000334370.4
MEGF8
multiple EGF-like-domains 8
chr4_+_108910870 0.17 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH
hydroxyacyl-CoA dehydrogenase
chr8_-_12612962 0.17 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr11_-_64511789 0.16 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr4_+_108911036 0.15 ENST00000505878.1
HADH
hydroxyacyl-CoA dehydrogenase
chr16_+_67282853 0.13 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr1_+_228395755 0.13 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr1_+_204797749 0.12 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
NFASC
neurofascin
chr15_+_57210961 0.12 ENST00000557843.1
TCF12
transcription factor 12
chr1_-_247094628 0.12 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AHCTF1
AT hook containing transcription factor 1
chr12_+_54519842 0.11 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chrX_-_17878827 0.11 ENST00000360011.1
RAI2
retinoic acid induced 2
chr1_+_202792385 0.11 ENST00000549576.1
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr13_+_96329381 0.11 ENST00000602402.1
ENST00000376795.6
DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr10_-_120938303 0.10 ENST00000356951.3
ENST00000298510.2
PRDX3
peroxiredoxin 3
chr21_-_30365136 0.08 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr1_+_173446405 0.08 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr3_-_155524049 0.07 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chr2_+_219524473 0.07 ENST00000439945.1
ENST00000431802.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr2_+_177025619 0.07 ENST00000410016.1
HOXD3
homeobox D3
chr10_+_7860460 0.07 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr13_-_37633567 0.06 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr10_+_50822083 0.05 ENST00000337653.2
ENST00000395562.2
CHAT
choline O-acetyltransferase
chr1_+_156611960 0.05 ENST00000361588.5
BCAN
brevican
chr19_+_57050317 0.05 ENST00000301318.3
ENST00000591844.1
ZFP28
ZFP28 zinc finger protein
chr8_-_144679296 0.05 ENST00000317198.6
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr15_-_43029252 0.05 ENST00000563260.1
ENST00000356231.3
CDAN1
codanin 1
chr9_-_99616642 0.04 ENST00000478850.1
ENST00000481138.1
ZNF782
zinc finger protein 782
chr1_+_156611704 0.04 ENST00000329117.5
BCAN
brevican
chr3_-_128902729 0.03 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr1_+_22970119 0.03 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
C1QC
complement component 1, q subcomponent, C chain
chr2_+_219524379 0.03 ENST00000443791.1
ENST00000359273.3
ENST00000392109.1
ENST00000392110.2
ENST00000423377.1
ENST00000392111.2
ENST00000412366.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr19_+_5681011 0.03 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_-_17488143 0.01 ENST00000599426.1
ENST00000252590.4
PLVAP
plasmalemma vesicle associated protein
chr3_-_151176497 0.01 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr2_+_235860616 0.01 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr20_-_54580523 0.00 ENST00000064571.2
CBLN4
cerebellin 4 precursor
chr17_-_74449252 0.00 ENST00000319380.7
UBE2O
ubiquitin-conjugating enzyme E2O
chr1_-_200379104 0.00 ENST00000367352.3
ZNF281
zinc finger protein 281
chr13_+_50202435 0.00 ENST00000282026.1
ARL11
ADP-ribosylation factor-like 11
chr22_-_50964558 0.00 ENST00000535425.1
ENST00000439934.1
SCO2
SCO2 cytochrome c oxidase assembly protein

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 1.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 0.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 1.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 1.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 4.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.5 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 1.2 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 3.9 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 3.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:1904796 regulation of core promoter binding(GO:1904796)
0.0 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.9 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 5.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 1.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 4.3 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 5.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.7 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 1.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.4 GO:0090541 MIT domain binding(GO:0090541)
0.1 1.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR