ISMARA results: ZNF384

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZNF384

Z-value: 1.53

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Transcription factors associated with ZNF384

Gene Symbol	Gene ID	Gene Info
ZNF384 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000126746.13	zinc finger protein 384

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZNF384	hg19_v2_chr12_-_6798616_6798684	0.33	7.7e-02	Click!

Activity profile of ZNF384 motif

Sorted Z-values of ZNF384 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_+_100354442 Show fit	6.09	ENST00000475887.1	GPR128 Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 128
chr3_-_197676740 Show fit	5.27	ENST00000452735.1 ENST00000453254.1 ENST00000455191.1	IQCG Ensembl NCBI GeneCards UniProt NextProt Show fit	IQ motif containing G
chr1_+_38022572 Show fit	5.24	ENST00000541606.1	DNALI1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, axonemal, light intermediate chain 1
chr6_+_116937636 Show fit	5.13	ENST00000368581.4 ENST00000229554.5 ENST00000368580.4	RSPH4A Ensembl NCBI GeneCards UniProt NextProt Show fit	radial spoke head 4 homolog A (Chlamydomonas)
chr12_-_58329819 Show fit	4.57	ENST00000551421.1	RP11-620J15.3 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-620J15.3
chr1_-_109655377 Show fit	4.42	ENST00000369948.3	C1orf194 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 194
chr16_-_28621353 Show fit	4.39	ENST00000567512.1	SULT1A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrY_+_2709527 Show fit	4.28	ENST00000250784.8	RPS4Y1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S4, Y-linked 1
chr1_-_109655355 Show fit	4.28	ENST00000369945.3	C1orf194 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 194
chr3_+_63638339 Show fit	4.27	ENST00000343837.3 ENST00000469440.1	SNTN Ensembl NCBI GeneCards UniProt NextProt Show fit	sentan, cilia apical structure protein

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF384

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	23.3	GO:0035082	axoneme assembly(GO:0035082)
0.9	9.7	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2	8.4	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.3	8.3	GO:0051923	sulfation(GO:0051923)
0.2	6.8	GO:0003341	cilium movement(GO:0003341)
0.2	6.6	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.9	5.7	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.5	5.5	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	5.0	GO:0000209	protein polyubiquitination(GO:0000209)
1.4	4.3	GO:0006756	dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)

Showing 1 to 10 of 542 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	26.7	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1	8.6	GO:0005814	centriole(GO:0005814)
0.0	8.6	GO:0005929	cilium(GO:0005929)
0.0	8.5	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.7	8.2	GO:0036157	outer dynein arm(GO:0036157)
2.6	7.8	GO:0001534	radial spoke(GO:0001534)
1.0	6.8	GO:0002177	manchette(GO:0002177)
0.3	5.9	GO:0036038	MKS complex(GO:0036038)
0.3	4.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2	4.5	GO:0042613	MHC class II protein complex(GO:0042613)

Showing 1 to 10 of 223 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	15.2	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	7.7	GO:0030544	Hsp70 protein binding(GO:0030544)
1.4	5.7	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.2	5.0	GO:0070840	dynein complex binding(GO:0070840)
0.7	4.9	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1	4.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.4	4.5	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2	4.5	GO:0070330	aromatase activity(GO:0070330)
0.4	4.0	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.1	3.8	GO:0045505	dynein intermediate chain binding(GO:0045505)

Showing 1 to 10 of 340 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	4.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	3.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	2.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	2.0	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.9	PID BMP PATHWAY	BMP receptor signaling
0.1	1.8	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	1.8	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.8	PID E2F PATHWAY	E2F transcription factor network

Showing 1 to 10 of 42 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.4	6.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	4.1	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	3.9	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	3.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	3.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	3.2	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	2.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.3	2.4	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	2.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling

Showing 1 to 10 of 80 entries

Results for ZNF384

Z-value: 1.53

Motif logo

Transcription factors associated with ZNF384

Activity-expression correlation:

Activity profile of ZNF384 motif

Sorted Z-values of ZNF384 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF384

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: