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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ZNF652

Z-value: 0.72

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Transcription factors associated with ZNF652

Gene Symbol Gene ID Gene Info
ENSG00000198740.4 zinc finger protein 652

Activity profile of ZNF652 motif

Sorted Z-values of ZNF652 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_89224508 1.75 ENST00000525196.1
NADPH oxidase 4
chr11_-_89224488 1.43 ENST00000534731.1
ENST00000527626.1
NADPH oxidase 4
chr11_-_89224299 1.37 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NADPH oxidase 4
chr7_+_80231466 1.30 ENST00000309881.7
ENST00000534394.1
CD36 molecule (thrombospondin receptor)
chr22_-_37880543 1.15 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_+_23286182 1.09 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
glycoprotein (transmembrane) nmb
chr12_-_6982442 1.04 ENST00000523102.1
ENST00000524270.1
ENST00000519357.1
splA/ryanodine receptor domain and SOCS box containing 2
chr10_-_28623368 1.04 ENST00000441595.2
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr11_-_89224638 1.02 ENST00000535633.1
ENST00000263317.4
NADPH oxidase 4
chr5_-_54281407 0.90 ENST00000381403.4
endothelial cell-specific molecule 1
chr16_-_56459354 0.85 ENST00000290649.5
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr11_-_111782484 0.84 ENST00000533971.1
crystallin, alpha B
chr5_+_135394840 0.73 ENST00000503087.1
transforming growth factor, beta-induced, 68kDa
chr11_-_111782696 0.69 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr17_+_48172639 0.68 ENST00000503176.1
ENST00000503614.1
pyruvate dehydrogenase kinase, isozyme 2
chr18_-_5296138 0.67 ENST00000400143.3
zinc finger and BTB domain containing 14
chr1_-_185597619 0.66 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
chr9_+_74764278 0.63 ENST00000238018.4
ENST00000376989.3
guanine deaminase
chr1_-_6662919 0.61 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chr5_+_167181917 0.61 ENST00000519204.1
teneurin transmembrane protein 2
chr2_+_38893208 0.59 ENST00000410063.1
galactose mutarotase (aldose 1-epimerase)
chr16_-_79634595 0.56 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr17_+_72733350 0.56 ENST00000392613.5
ENST00000392612.3
ENST00000392610.1
RAB37, member RAS oncogene family
chr17_-_6735012 0.55 ENST00000535086.1
tektin 1
chr1_+_152635854 0.52 ENST00000368784.1
late cornified envelope 2D
chr19_+_46651474 0.52 ENST00000377693.4
IGF-like family member 2
chr4_+_72897521 0.51 ENST00000308744.6
ENST00000344413.5
neuropeptide FF receptor 2
chr5_-_147211226 0.51 ENST00000296695.5
serine peptidase inhibitor, Kazal type 1
chr8_-_140715294 0.50 ENST00000303015.1
ENST00000520439.1
potassium channel, subfamily K, member 9
chrX_-_128788914 0.49 ENST00000429967.1
ENST00000307484.6
apelin
chr12_+_6982725 0.49 ENST00000433346.1
leucine rich repeat containing 23
chr20_-_36793663 0.48 ENST00000536701.1
ENST00000536724.1
transglutaminase 2
chr19_-_14316980 0.46 ENST00000361434.3
ENST00000340736.6
latrophilin 1
chrX_-_44202857 0.44 ENST00000420999.1
EF-hand domain (C-terminal) containing 2
chr14_+_22771851 0.43 ENST00000390466.1
T cell receptor alpha variable 39
chr17_+_26800296 0.43 ENST00000444914.3
ENST00000314669.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr12_+_20848486 0.42 ENST00000545102.1
solute carrier organic anion transporter family, member 1C1
chr12_+_20848377 0.41 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
solute carrier organic anion transporter family, member 1C1
chr17_+_12569306 0.41 ENST00000425538.1
myocardin
chr1_+_145293371 0.41 ENST00000342960.5
neuroblastoma breakpoint family, member 10
chr6_+_46655612 0.40 ENST00000544460.1
tudor domain containing 6
chr17_+_26800648 0.39 ENST00000545060.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr11_-_63381925 0.39 ENST00000415826.1
phospholipase A2, group XVI
chr3_+_121774202 0.39 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86 molecule
chr17_+_26800756 0.39 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr10_+_104263743 0.38 ENST00000369902.3
ENST00000369899.2
ENST00000423559.2
suppressor of fused homolog (Drosophila)
chr1_+_86934526 0.37 ENST00000394711.1
chloride channel accessory 1
chr2_-_86564776 0.37 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr3_+_183353356 0.36 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
kelch-like family member 24
chr9_+_132096166 0.36 ENST00000436710.1
RP11-65J3.1
chr9_+_74764340 0.35 ENST00000376986.1
ENST00000358399.3
guanine deaminase
chr2_-_61244308 0.35 ENST00000407787.1
ENST00000398658.2
pseudouridylate synthase 10
chr13_+_111267866 0.34 ENST00000458711.2
ENST00000424185.2
ENST00000397191.4
ENST00000309957.2
carbohydrate kinase domain containing
chr4_-_99578776 0.34 ENST00000515287.1
tetraspanin 5
chr6_-_51952418 0.34 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr5_-_153857819 0.33 ENST00000231121.2
heart and neural crest derivatives expressed 1
chr4_-_165898768 0.33 ENST00000329314.5
tripartite motif containing 61
chr1_+_202431859 0.33 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr11_-_86383370 0.33 ENST00000526834.1
ENST00000359636.2
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr14_-_88459503 0.33 ENST00000393568.4
ENST00000261304.2
galactosylceramidase
chr11_-_86383157 0.32 ENST00000393324.3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr14_+_79745746 0.32 ENST00000281127.7
neurexin 3
chr1_-_221915418 0.32 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr15_+_71185148 0.32 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr15_-_38856836 0.32 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr20_-_36793774 0.32 ENST00000361475.2
transglutaminase 2
chrX_-_110513703 0.32 ENST00000324068.1
calpain 6
chr6_-_55740352 0.31 ENST00000370830.3
bone morphogenetic protein 5
chr14_+_79746249 0.30 ENST00000428277.2
neurexin 3
chr15_-_49255632 0.30 ENST00000332408.4
SHC (Src homology 2 domain containing) family, member 4
chr17_-_4689727 0.29 ENST00000328739.5
ENST00000354194.4
vitelline membrane outer layer 1 homolog (chicken)
chr16_+_31470179 0.29 ENST00000538189.1
ENST00000268314.4
armadillo repeat containing 5
chr16_+_31470143 0.28 ENST00000457010.2
ENST00000563544.1
armadillo repeat containing 5
chr14_+_24867992 0.28 ENST00000382554.3
NYN domain and retroviral integrase containing
chr7_+_1127723 0.28 ENST00000397088.3
G protein-coupled estrogen receptor 1
chr16_-_57570450 0.28 ENST00000258214.2
coiled-coil domain containing 102A
chr17_+_47865917 0.28 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
K(lysine) acetyltransferase 7
chr19_+_10531150 0.28 ENST00000352831.6
phosphodiesterase 4A, cAMP-specific
chr10_-_15413035 0.27 ENST00000378116.4
ENST00000455654.1
family with sequence similarity 171, member A1
chr3_-_133648656 0.27 ENST00000408895.2
chromosome 3 open reading frame 36
chr4_-_77134742 0.27 ENST00000452464.2
scavenger receptor class B, member 2
chr19_-_55881741 0.27 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
interleukin 11
chr16_-_57513657 0.27 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
docking protein 4
chr14_-_22005343 0.26 ENST00000327430.3
spalt-like transcription factor 2
chr12_+_32112340 0.26 ENST00000540924.1
ENST00000312561.4
KIAA1551
chr6_+_26217159 0.26 ENST00000303910.2
histone cluster 1, H2ae
chr20_-_43753104 0.26 ENST00000372785.3
WAP four-disulfide core domain 12
chrX_-_154250989 0.25 ENST00000360256.4
coagulation factor VIII, procoagulant component
chr12_-_11139511 0.25 ENST00000506868.1
taste receptor, type 2, member 50
chr11_-_128894053 0.25 ENST00000392657.3
Rho GTPase activating protein 32
chr16_-_1843720 0.25 ENST00000415638.3
ENST00000215539.3
insulin-like growth factor binding protein, acid labile subunit
chr1_+_22351977 0.25 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
long intergenic non-protein coding RNA 339
chr11_-_62752162 0.25 ENST00000458333.2
ENST00000421062.2
solute carrier family 22 (organic anion transporter), member 6
chr17_-_66287350 0.24 ENST00000580666.1
ENST00000583477.1
solute carrier family 16, member 6
chr2_+_11052054 0.24 ENST00000295082.1
potassium voltage-gated channel, subfamily F, member 1
chr14_-_65769392 0.24 ENST00000555736.1
CTD-2509G16.5
chr3_+_49209023 0.24 ENST00000332780.2
kelch domain containing 8B
chr7_-_121944491 0.23 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr5_-_157002775 0.23 ENST00000257527.4
ADAM metallopeptidase domain 19
chr14_-_101034407 0.23 ENST00000443071.2
ENST00000557378.1
brain-enriched guanylate kinase-associated
chr7_-_92465868 0.23 ENST00000424848.2
cyclin-dependent kinase 6
chr13_-_38172863 0.22 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr11_-_59951889 0.22 ENST00000532169.1
ENST00000534596.1
membrane-spanning 4-domains, subfamily A, member 6A
chr14_+_85996507 0.22 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr3_-_193272874 0.22 ENST00000342695.4
ATPase type 13A4
chr3_-_193272741 0.22 ENST00000392443.3
ATPase type 13A4
chr8_+_66955648 0.22 ENST00000522619.1
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr2_-_15701422 0.22 ENST00000441750.1
ENST00000281513.5
neuroblastoma amplified sequence
chr14_-_69263043 0.22 ENST00000408913.2
ZFP36 ring finger protein-like 1
chr11_+_57365150 0.22 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_+_22333943 0.21 ENST00000400271.2
chymotrypsin-like elastase family, member 3A
chr1_-_182641037 0.21 ENST00000483095.2
regulator of G-protein signaling 8
chr2_-_190044480 0.21 ENST00000374866.3
collagen, type V, alpha 2
chr22_-_24641027 0.21 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
gamma-glutamyltransferase 5
chr2_+_204193129 0.21 ENST00000417864.1
abl-interactor 2
chr6_+_109169591 0.20 ENST00000368972.3
ENST00000392644.4
armadillo repeat containing 2
chr2_-_192016316 0.20 ENST00000358470.4
ENST00000432798.1
ENST00000450994.1
signal transducer and activator of transcription 4
chr14_-_22005062 0.20 ENST00000317492.5
spalt-like transcription factor 2
chr12_+_7072354 0.20 ENST00000537269.1
U47924.27
chr1_-_1182102 0.20 ENST00000330388.2
family with sequence similarity 132, member A
chr6_+_152126790 0.20 ENST00000456483.2
estrogen receptor 1
chr8_-_145018080 0.20 ENST00000354589.3
plectin
chr7_-_127255982 0.19 ENST00000338516.3
ENST00000378740.2
paired box 4
chr1_-_156647189 0.19 ENST00000368223.3
nestin
chr1_-_182640988 0.19 ENST00000367556.1
regulator of G-protein signaling 8
chr9_+_131683174 0.19 ENST00000372592.3
ENST00000428610.1
phytanoyl-CoA dioxygenase domain containing 1
chr14_-_21562648 0.19 ENST00000555270.1
zinc finger protein 219
chr12_+_10460549 0.19 ENST00000543420.1
ENST00000543777.1
killer cell lectin-like receptor subfamily D, member 1
chr19_+_45349630 0.19 ENST00000252483.5
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr12_-_6809958 0.19 ENST00000320591.5
ENST00000534837.1
PILR alpha associated neural protein
chr15_+_68871569 0.19 ENST00000566799.1
coronin, actin binding protein, 2B
chr5_-_78281775 0.19 ENST00000396151.3
ENST00000565165.1
arylsulfatase B
chr5_-_178054014 0.19 ENST00000520957.1
CDC-like kinase 4
chr14_-_106926724 0.18 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr12_-_6451186 0.18 ENST00000540022.1
ENST00000536194.1
tumor necrosis factor receptor superfamily, member 1A
chr7_-_137686791 0.18 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
cAMP responsive element binding protein 3-like 2
chr16_+_67927147 0.18 ENST00000291041.5
protein serine kinase H1
chr1_+_181003067 0.17 ENST00000434571.2
ENST00000367579.3
ENST00000282990.6
ENST00000367580.5
major histocompatibility complex, class I-related
chr2_-_188378368 0.17 ENST00000392365.1
ENST00000435414.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_+_39760783 0.17 ENST00000398904.2
ENST00000538976.1
dishevelled associated activator of morphogenesis 2
chr8_-_7309887 0.17 ENST00000458665.1
ENST00000528168.1
sperm associated antigen 11B
chr14_-_21493884 0.17 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr11_-_26593649 0.17 ENST00000455601.2
mucin 15, cell surface associated
chr3_+_46412345 0.17 ENST00000292303.4
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr3_-_141719195 0.17 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_-_157002749 0.17 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM metallopeptidase domain 19
chr16_+_53242350 0.16 ENST00000565442.1
chromodomain helicase DNA binding protein 9
chr14_+_31343951 0.16 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
cochlin
chr15_+_63569785 0.16 ENST00000380343.4
ENST00000560353.1
APH1B gamma secretase subunit
chr4_-_34041504 0.16 ENST00000512581.1
ENST00000505018.1
RP11-79E3.3
chr12_-_6809543 0.16 ENST00000540656.1
PILR alpha associated neural protein
chr16_-_75285380 0.16 ENST00000393420.6
ENST00000162330.5
breast cancer anti-estrogen resistance 1
chr11_-_59633951 0.16 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr20_-_60942361 0.15 ENST00000252999.3
laminin, alpha 5
chr14_+_24407940 0.15 ENST00000354854.1
DHRS4-AS1
chr2_+_38893047 0.15 ENST00000272252.5
galactose mutarotase (aldose 1-epimerase)
chr16_+_24266874 0.15 ENST00000005284.3
calcium channel, voltage-dependent, gamma subunit 3
chr10_-_28571015 0.15 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr6_-_134373732 0.15 ENST00000275230.5
solute carrier family 2 (facilitated glucose transporter), member 12
chr17_-_7120525 0.15 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
discs, large homolog 4 (Drosophila)
chr17_-_46035187 0.15 ENST00000300557.2
proline rich 15-like
chr7_-_150675372 0.15 ENST00000262186.5
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr14_-_21493649 0.15 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr8_+_7716700 0.15 ENST00000454911.2
ENST00000326625.5
sperm associated antigen 11A
chr6_-_28226984 0.14 ENST00000423974.2
zinc finger with KRAB and SCAN domains 4
chr3_+_135969148 0.14 ENST00000251654.4
ENST00000490504.1
ENST00000483687.1
ENST00000468777.1
ENST00000462637.1
ENST00000466072.1
ENST00000482086.1
ENST00000471595.1
ENST00000469217.1
ENST00000465423.1
ENST00000478469.1
propionyl CoA carboxylase, beta polypeptide
chr4_-_143226979 0.14 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr9_+_109694914 0.14 ENST00000542028.1
zinc finger protein 462
chr7_-_142583506 0.14 ENST00000359396.3
transient receptor potential cation channel, subfamily V, member 6
chr3_+_113616317 0.14 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr4_-_103998439 0.14 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr5_+_152870287 0.14 ENST00000340592.5
glutamate receptor, ionotropic, AMPA 1
chr16_+_84733575 0.14 ENST00000219473.7
ENST00000563892.1
ENST00000562283.1
ENST00000570191.1
ENST00000569038.1
ENST00000570053.1
ubiquitin specific peptidase 10
chr10_-_61513146 0.13 ENST00000430431.1
long intergenic non-protein coding RNA 948
chr20_-_17662705 0.13 ENST00000455029.2
ribosome binding protein 1
chr9_+_130860583 0.13 ENST00000373064.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr12_+_56546223 0.13 ENST00000550443.1
ENST00000207437.5
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr4_-_130014532 0.13 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
sodium channel and clathrin linker 1
chr9_-_115983568 0.13 ENST00000446284.1
ENST00000414250.1
FK506 binding protein 15, 133kDa
chr9_+_130860810 0.13 ENST00000433501.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr1_-_33168336 0.13 ENST00000373484.3
syncoilin, intermediate filament protein
chr6_-_46048116 0.13 ENST00000185206.6
chloride intracellular channel 5
chr14_-_67982146 0.13 ENST00000557779.1
ENST00000557006.1
transmembrane protein 229B
chr6_-_16761678 0.13 ENST00000244769.4
ENST00000436367.1
ataxin 1
chr3_+_113251143 0.13 ENST00000264852.4
ENST00000393830.3
SID1 transmembrane family, member 1
chr1_-_150849047 0.13 ENST00000354396.2
ENST00000505755.1
aryl hydrocarbon receptor nuclear translocator
chr12_-_6451235 0.13 ENST00000440083.2
ENST00000162749.2
tumor necrosis factor receptor superfamily, member 1A
chr2_-_68547061 0.12 ENST00000263655.3
cannabinoid receptor interacting protein 1
chr2_+_223536428 0.12 ENST00000446656.3
monoacylglycerol O-acyltransferase 1
chr22_+_39966758 0.12 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr16_-_30798492 0.12 ENST00000262525.4
zinc finger protein 629
chr4_+_74275057 0.12 ENST00000511370.1
albumin
chr12_-_58329888 0.12 ENST00000546580.1
RP11-620J15.3
chr2_+_204193149 0.12 ENST00000422511.2
abl-interactor 2
chr2_-_99224915 0.12 ENST00000328709.3
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr3_+_151531810 0.12 ENST00000232892.7
arylacetamide deacetylase
chr6_+_28227063 0.11 ENST00000343684.3
NFKB activating protein-like
chr17_-_41985096 0.11 ENST00000269095.4
ENST00000523220.1
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr15_-_34880646 0.11 ENST00000543376.1
golgin A8 family, member A
chr22_-_29196546 0.11 ENST00000403532.3
ENST00000216037.6
X-box binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF652

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 1.0 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 0.7 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 1.3 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.7 GO:2000724 positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.2 5.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.2 0.5 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.4 GO:0097254 renal tubular secretion(GO:0097254)
0.1 1.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.9 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.3 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.5 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 1.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.2 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 0.3 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.2 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.0 0.4 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.3 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.5 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.7 GO:0003170 heart valve development(GO:0003170)
0.0 0.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0043259 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.4 1.2 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.3 0.9 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.3 1.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.7 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.3 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.8 GO:0045545 syndecan binding(GO:0045545)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.2 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.0 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.3 GO:0032947 protein complex scaffold(GO:0032947)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 5.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2