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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for ZNF784
Z-value: 0.97
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Transcription factors associated with ZNF784
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF784 | hg19_v2_chr19_-_56135928_56135967 | -0.59 | 6.0e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_41029235 Show fit | 4.74 |
ENST00000380618.1
|
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 |
|
| chr1_-_153029980 Show fit | 4.19 |
ENST00000392653.2
|
small proline-rich protein 2A |
|
| chr22_-_37640456 Show fit | 3.89 |
ENST00000405484.1
ENST00000441619.1 ENST00000406508.1 |
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
|
| chr22_-_37640277 Show fit | 3.76 |
ENST00000401529.3
ENST00000249071.6 |
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
|
| chr15_+_40453204 Show fit | 3.75 |
ENST00000287598.6
ENST00000412359.3 |
BUB1 mitotic checkpoint serine/threonine kinase B |
|
| chr1_+_32042131 Show fit | 3.62 |
ENST00000271064.7
ENST00000537531.1 |
tubulointerstitial nephritis antigen-like 1 |
|
| chr1_+_32042105 Show fit | 3.61 |
ENST00000457433.2
ENST00000441210.2 |
tubulointerstitial nephritis antigen-like 1 |
|
| chr15_-_74501360 Show fit | 3.05 |
ENST00000323940.5
|
stimulated by retinoic acid 6 |
|
| chr18_+_21529811 Show fit | 2.76 |
ENST00000588004.1
|
laminin, alpha 3 |
|
| chr2_-_72375167 Show fit | 2.50 |
ENST00000001146.2
|
cytochrome P450, family 26, subfamily B, polypeptide 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF784
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.7 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.7 | 7.9 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.0 | 7.3 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.7 | 4.3 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.1 | 4.2 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.9 | 3.7 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.7 | 3.6 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.3 | 3.5 | GO:1902172 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
| 0.0 | 3.5 | GO:0070268 | cornification(GO:0070268) |
| 0.3 | 3.4 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.3 | 6.6 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.3 | 4.6 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.3 | 4.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 4.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 3.4 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 3.2 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.6 | 3.1 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.3 | 3.1 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 3.1 | GO:0034451 | centriolar satellite(GO:0034451) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.2 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 8.2 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.3 | 7.0 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.3 | 5.0 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.1 | 5.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.3 | 4.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 4.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 3.6 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 3.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 3.2 | GO:0031490 | chromatin DNA binding(GO:0031490) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 8.6 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 7.9 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 7.1 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 4.3 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 3.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 3.3 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 3.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 3.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 3.1 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 2.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.4 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.2 | 7.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 4.9 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.1 | 4.7 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.1 | 3.3 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 3.2 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 3.1 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.1 | 2.3 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 2.1 | REACTOME BIOLOGICAL OXIDATIONS | Genes involved in Biological oxidations |
| 0.1 | 2.0 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |