Motif ID: TLX2.p2

Z-value: 0.867


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX2chr2_+_74740585-0.216.1e-01Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_120935893 1.497 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr12_+_13044493 1.402 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr12_+_13044352 1.309 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr18_+_29027731 1.303 NM_001944
 DSG3
desmoglein 3
chr1_+_86889768 1.270 NM_006536
 CLCA2
chloride channel accessory 2
chr20_-_14318200 1.026 NM_013281
NM_198391
 FLRT3

fibronectin leucine rich transmembrane protein 3

chr1_-_153363544 1.023 NM_002964
 S100A8
S100 calcium binding protein A8
chr18_-_28681885 1.013 NM_004949
NM_024422
 DSC2

desmocollin 2

chr10_+_48255223 1.005 NM_001040084
NM_001098845
 ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr1_-_21059132 0.999 NM_001103160
NM_001103161
 SH2D5

SH2 domain containing 5

chr12_-_8815266 0.968 MFAP5
microfibrillar associated protein 5
chr20_+_58251715 0.941 NM_001199506
 PHACTR3
phosphatase and actin regulator 3
chr20_-_43883183 0.936 NM_003064
 SLPI
secretory leukocyte peptidase inhibitor
chr16_-_68269948 0.923 NM_024939
 ESRP2
epithelial splicing regulatory protein 2
chr5_-_60140041 0.886 NM_001104558
NM_024930
 ELOVL7

ELOVL fatty acid elongase 7

chr15_+_41136178 0.880 NM_003710
NM_181642
 SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_+_95286099 0.877 NM_152369
 SLC44A3
solute carrier family 44, member 3
chr1_+_95286193 0.874 SLC44A3
solute carrier family 44, member 3
chr1_+_152486977 0.865 NM_019060
 CRCT1
cysteine-rich C-terminal 1
chr9_-_33447527 0.827 NM_004925
 AQP3
aquaporin 3 (Gill blood group)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.96 1.58e-02 GO:0061061 muscle structure development
1.49 7.19e-04 GO:0002376 immune system process
1.33 1.71e-02 GO:0048513 organ development
1.31 3.45e-04 GO:0048731 system development
1.29 4.06e-04 GO:0048856 anatomical structure development
1.27 6.89e-04 GO:0007275 multicellular organismal development
1.24 3.03e-03 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.80 3.05e-02 GO:0016459 myosin complex
1.88 2.24e-04 GO:0009986 cell surface
1.55 6.61e-03 GO:0005789 endoplasmic reticulum membrane
1.54 5.84e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.51 7.55e-03 GO:0044432 endoplasmic reticulum part
1.50 1.80e-05 GO:0031226 intrinsic to plasma membrane
1.50 2.28e-05 GO:0005887 integral to plasma membrane
1.46 2.80e-02 GO:0005615 extracellular space
1.45 1.91e-03 GO:0005783 endoplasmic reticulum
1.38 4.52e-02 GO:0044421 extracellular region part
1.37 1.79e-05 GO:0044459 plasma membrane part
1.36 2.75e-03 GO:0012505 endomembrane system
1.27 6.06e-10 GO:0031224 intrinsic to membrane
1.27 1.36e-09 GO:0016021 integral to membrane
1.22 2.32e-08 GO:0044425 membrane part
1.18 1.47e-02 GO:0005886 plasma membrane
1.18 2.22e-02 GO:0071944 cell periphery
1.17 2.48e-06 GO:0016020 membrane
1.04 2.05e-02 GO:0044464 cell part
1.04 2.11e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.50 3.42e-02 GO:0015081 sodium ion transmembrane transporter activity
2.22 1.31e-02 GO:0046873 metal ion transmembrane transporter activity
1.45 6.88e-03 GO:0005102 receptor binding