Motif ID: AAUACUG

Z-value: 1.464


Mature miRNA associated with seed AAUACUG:

NamemiRBase Accession
hsa-miR-200b MIMAT0000318
hsa-miR-200c MIMAT0000617
hsa-miR-429 MIMAT0001536



Activity profile for motif AAUACUG.

activity profile for motif AAUACUG


Sorted Z-values histogram for motif AAUACUG

Sorted Z-values for motif AAUACUG



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUACUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_31608097 2.866 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr1_+_183605207 2.746 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr10_+_31610063 2.669 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr1_-_57045235 2.574 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_72748147 2.253 NM_173808
NEGR1
neuronal growth regulator 1
chr8_-_12973752 2.004 NM_001164271
DLC1
deleted in liver cancer 1
chr8_-_12990731 1.896 NM_006094
DLC1
deleted in liver cancer 1
chr12_-_47219734 1.860 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr17_-_76921453 1.850 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr2_-_145277879 1.664 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr2_-_175499275 1.630 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr2_+_210288668 1.616 NM_001039538
MAP2
microtubule-associated protein 2
chr2_-_175547471 1.596 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr2_+_210444364 1.587 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr10_-_81205091 1.572 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr13_-_33760215 1.558 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33780142 1.463 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33859835 1.423 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr8_+_70405027 1.352 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr12_-_15942350 1.318 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr6_-_139695349 1.271 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chr6_-_139695784 1.258 NM_006079
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr8_+_97505876 1.210 NM_002998
SDC2
syndecan 2
chr19_-_11308184 1.191 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr9_+_36036900 1.158 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr2_-_38303307 1.143 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr5_-_172198160 1.135 NM_004417
DUSP1
dual specificity phosphatase 1
chr5_-_111312522 1.131 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr5_-_111093251 1.131 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr8_+_70378858 1.125 NM_001128204
NM_015170
SULF1

sulfatase 1

chr5_-_111093030 1.124 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr5_-_111092918 1.113 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr8_+_79428335 1.111 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr5_-_111093792 1.107 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr19_-_11305186 0.985 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr12_-_31743822 0.957 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr5_-_121412805 0.923 NM_001178102
LOX
lysyl oxidase
chr2_-_214016332 0.911 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_-_167275657 0.908 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr5_-_121414011 0.902 NM_002317
LOX
lysyl oxidase
chrX_-_15873094 0.902 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr13_+_76194569 0.883 NM_005358
LMO7
LIM domain 7
chr7_-_139477437 0.870 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr6_-_167040700 0.861 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_201170603 0.859 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr5_-_14871555 0.834 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr9_-_113800243 0.830 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr13_+_76334796 0.825 NM_015842
LMO7
LIM domain 7
chr21_-_34100228 0.813 NM_001160302
NM_001160306
SYNJ1

synaptojanin 1

chr19_+_15218141 0.795 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr2_+_201170795 0.754 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr13_+_93879011 0.739 NM_005708
GPC6
glypican 6
chr12_+_26126687 0.725 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr9_-_138987096 0.722 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr7_+_8008416 0.720 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr12_+_79257772 0.719 NM_001135805
SYT1
synaptotagmin I
chr2_-_167232464 0.704 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr4_+_160188997 0.703 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr21_-_34100316 0.695 NM_003895
NM_203446
SYNJ1

synaptojanin 1

chr14_-_61115906 0.687 NM_005982
SIX1
SIX homeobox 1
chr1_+_213123853 0.678 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr3_-_15900928 0.677 NM_015199
ANKRD28
ankyrin repeat domain 28
chr8_-_93115453 0.672 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr3_-_178789597 0.670 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr8_-_93029864 0.664 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_114178516 0.662 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr12_+_79439432 0.654 NM_001135806
SYT1
synaptotagmin I
chr8_+_42128797 0.651 NM_001190720
NM_001242778
NM_001556
IKBKB


inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta


chr3_-_120169493 0.649 NM_007085
FSTL1
follistatin-like 1
chr17_+_19281726 0.649 NM_002749
NM_139034
MAPK7

mitogen-activated protein kinase 7

chr3_+_141043054 0.636 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr5_-_111091947 0.629 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr11_+_118478305 0.625 NM_001144758
NM_001144759
PHLDB1

pleckstrin homology-like domain, family B, member 1

chr10_-_14372807 0.621 NM_018027
FRMD4A
FERM domain containing 4A
chr7_-_28220342 0.614 NM_175061
JAZF1
JAZF zinc finger 1
chr17_+_19281013 0.611 NM_139032
NM_139033
MAPK7

mitogen-activated protein kinase 7

chr5_+_71403040 0.610 NM_005909
MAP1B
microtubule-associated protein 1B
chr12_+_57522247 0.610 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr12_+_26205490 0.598 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr16_+_8768403 0.595 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr12_+_79258448 0.592 NM_005639
SYT1
synaptotagmin I
chr8_-_93111915 0.588 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_63536112 0.588 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr11_+_120195837 0.587 NM_001198670
NM_001198671
NM_001198672
NM_001198673
NM_001198674
NM_001198675
NM_174926
TMEM136






transmembrane protein 136






chrX_-_99665270 0.570 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr16_+_4382224 0.568 NM_032575
GLIS2
GLIS family zinc finger 2
chr8_-_93107881 0.563 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr8_-_93107442 0.561 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr4_-_89618928 0.560 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr16_+_8814567 0.553 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr6_-_154831704 0.551 NM_173515
CNKSR3
CNKSR family member 3
chr2_-_214015053 0.545 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr16_+_1359622 0.541 NM_003345
NM_194259
UBE2I

ubiquitin-conjugating enzyme E2I

chr7_-_27183225 0.535 NM_019102
HOXA5
homeobox A5
chr1_-_1624180 0.534 NM_001110781
SLC35E2B
solute carrier family 35, member E2B
chr14_-_75593720 0.532 NM_033116
NEK9
NIMA (never in mitosis gene a)- related kinase 9
chr11_+_111848008 0.521 NM_033425
DIXDC1
DIX domain containing 1
chr6_+_11538486 0.520 NM_001100829
TMEM170B
transmembrane protein 170B
chr2_+_237993954 0.495 NM_006710
NM_198189
COPS8

COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)

chr3_+_185000714 0.490 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr2_+_205410465 0.488 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr17_-_36956145 0.487 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr15_-_82338348 0.487 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr20_+_39766128 0.486 NM_002660
NM_182811
PLCG1

phospholipase C, gamma 1

chr16_+_1359153 0.481 NM_194260
NM_194261
UBE2I

ubiquitin-conjugating enzyme E2I

chr2_-_19558371 0.479 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr19_+_34745452 0.473 NM_014686
KIAA0355
KIAA0355
chr16_+_8806825 0.467 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr2_-_85839178 0.461 NM_001013649
C2orf68
chromosome 2 open reading frame 68
chr8_-_13372183 0.458 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr17_-_38083762 0.457 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr11_+_12695851 0.456 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_-_82024277 0.451 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr6_+_30524485 0.448 NM_001077497
NM_025263
PRR3

proline rich 3

chr15_-_49338496 0.441 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr2_-_122406994 0.441 NM_001142273
NM_001142274
NM_001207051
NM_015282
CLASP1



cytoplasmic linker associated protein 1



chr14_+_77228132 0.439 NM_014909
VASH1
vasohibin 1
chr12_+_120105656 0.435 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr8_-_11058847 0.434 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr14_+_51955854 0.432 NM_001042481
FRMD6
FERM domain containing 6
chr6_-_52926588 0.430 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr1_+_202431870 0.429 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chrX_-_19988381 0.429 NM_198279
CXorf23
chromosome X open reading frame 23
chr9_-_73029539 0.425 NM_001206
KLF9
Kruppel-like factor 9
chr8_-_93075190 0.424 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_119215240 0.422 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr1_-_208417635 0.421 NM_025179
PLXNA2
plexin A2
chr1_+_202509241 0.415 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr6_+_126102278 0.414 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr17_+_57408907 0.410 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chr1_+_25071759 0.408 NM_013943
CLIC4
chloride intracellular channel 4
chr11_+_118477212 0.408 NM_015157
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr3_-_15839674 0.401 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr6_-_57087018 0.399 NM_016277
RAB23
RAB23, member RAS oncogene family
chr2_+_11886739 0.393 NM_145693
LPIN1
lipin 1
chr11_+_111807857 0.391 NM_001037954
DIXDC1
DIX domain containing 1
chr6_-_57086204 0.388 NM_183227
RAB23
RAB23, member RAS oncogene family
chr20_+_46130600 0.386 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr3_-_15798057 0.384 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr4_-_2263706 0.383 NM_006454
MXD4
MAX dimerization protein 4
chr11_+_73019662 0.381 NM_014786
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr1_+_33722158 0.380 NM_152493
ZNF362
zinc finger protein 362
chr10_+_104503724 0.380 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr6_-_137113624 0.377 NM_005923
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr9_-_15510899 0.376 NM_001128217
NM_033222
PSIP1

PC4 and SFRS1 interacting protein 1

chr14_+_52118539 0.369 NM_152330
FRMD6
FERM domain containing 6
chr19_+_49617611 0.369 NM_022165
LIN7B
lin-7 homolog B (C. elegans)
chr1_-_33647626 0.367 NM_018207
TRIM62
tripartite motif containing 62
chr13_-_96296919 0.365 NM_014934
NM_198968
DZIP1

DAZ interacting protein 1

chr7_-_6312137 0.361 NM_004227
CYTH3
cytohesin 3
chr12_-_52585686 0.358 NM_001081492
NM_182507
KRT80

keratin 80

chr9_+_112887780 0.357 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr10_+_104535887 0.354 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr2_+_23608297 0.352 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr9_-_127703294 0.352 NM_002077
GOLGA1
golgin A1
chr8_-_95961543 0.351 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr1_+_179923870 0.347 NM_014810
CEP350
centrosomal protein 350kDa
chr17_-_56065596 0.346 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr5_+_102201526 0.342 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr12_-_54653369 0.341 NM_001127321
CBX5
chromobox homolog 5
chr9_+_112810877 0.340 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr12_-_54653317 0.340 NM_001127322
CBX5
chromobox homolog 5
chr17_+_41323181 0.337 NM_005899
NBR1
neighbor of BRCA1 gene 1
chr14_-_35183722 0.335 NM_001243645
NM_138638
CFL2

cofilin 2 (muscle)

chr17_-_76778306 0.333 NM_004762
NM_017456
CYTH1

cytohesin 1

chr8_-_71316006 0.327 NM_006540
NCOA2
nuclear receptor coactivator 2
chr8_-_95907423 0.325 NM_057749
CCNE2
cyclin E2
chr12_-_96794207 0.324 NM_001170464
NM_002595
CDK17

cyclin-dependent kinase 17

chr5_-_89825292 0.323 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr14_-_67982020 0.323 NM_182526
TMEM229B
transmembrane protein 229B
chr5_-_90679115 0.323 NM_020801
ARRDC3
arrestin domain containing 3
chr5_+_76248679 0.321 NM_001882
CRHBP
corticotropin releasing hormone binding protein
chr7_-_73133917 0.316 NM_001165903
NM_004603
STX1A

syntaxin 1A (brain)

chr17_-_78450247 0.315 NM_002522
NPTX1
neuronal pentraxin I
chr12_+_26111951 0.314 NM_001164748
NM_007211
RASSF8

Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

chr7_+_2557496 0.314 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr14_-_35182944 0.313 NM_021914
CFL2
cofilin 2 (muscle)
chr1_+_61547625 0.310 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr12_+_104458235 0.307 NM_013320
HCFC2
host cell factor C2
chr11_-_9286832 0.307 NM_001243254
NM_015213
DENND5A

DENN/MADD domain containing 5A

chr9_+_34990266 0.306 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr12_+_12764755 0.305 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr7_+_2552162 0.304 NM_001166355
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_109125289 0.302 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr13_+_27131799 0.299 NM_006646
WASF3
WAS protein family, member 3
chr14_-_89020888 0.296 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr13_-_74707913 0.295 NM_007249
KLF12
Kruppel-like factor 12
chr17_+_66508525 0.290 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr11_-_66115016 0.290 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr3_+_73046081 0.289 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr6_+_136172802 0.286 NM_018945
PDE7B
phosphodiesterase 7B
chr8_+_77593506 0.286 NM_024721
ZFHX4
zinc finger homeobox 4
chr12_-_54673901 0.285 NM_012117
CBX5
chromobox homolog 5
chr3_-_66550844 0.281 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr10_-_23003443 0.279 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr15_+_62939509 0.279 NM_015059
TLN2
talin 2
chr7_+_104654494 0.279 NM_018682
NM_182931
MLL5

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

chr13_-_40177355 0.277 NM_005780
LHFP
lipoma HMGIC fusion partner
chr12_+_99038918 0.277 NM_001160
NM_013229
NM_181861
NM_181868
NM_181869
APAF1




apoptotic peptidase activating factor 1




chr14_+_29236171 0.276 NM_005249
FOXG1
forkhead box G1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 3.06e-07 GO:0050794 regulation of cellular process
2.66 2.18e-06 GO:0051253 negative regulation of RNA metabolic process
1.30 2.65e-06 GO:0050789 regulation of biological process
1.80 2.88e-06 GO:0006464 protein modification process
1.77 3.21e-06 GO:0043412 macromolecule modification
1.52 6.27e-06 GO:0080090 regulation of primary metabolic process
1.84 6.50e-06 GO:0023051 regulation of signaling
1.49 9.23e-06 GO:0023052 signaling
1.28 9.70e-06 GO:0065007 biological regulation
2.60 1.02e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.60 1.77e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 1.77e-05 GO:0031323 regulation of cellular metabolic process
1.64 1.78e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.43 1.82e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.43 2.66e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.40 3.95e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
2.32 4.17e-05 GO:0031327 negative regulation of cellular biosynthetic process
2.07 4.35e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.64 5.73e-05 GO:0051252 regulation of RNA metabolic process
1.50 6.57e-05 GO:0060255 regulation of macromolecule metabolic process
1.44 6.95e-05 GO:0019222 regulation of metabolic process
2.32 7.59e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.65 7.79e-05 GO:0048523 negative regulation of cellular process
1.41 8.01e-05 GO:0044260 cellular macromolecule metabolic process
2.27 8.19e-05 GO:0009890 negative regulation of biosynthetic process
1.60 8.50e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.55 1.14e-04 GO:0051171 regulation of nitrogen compound metabolic process
2.36 1.24e-04 GO:0010629 negative regulation of gene expression
1.48 1.35e-04 GO:0007165 signal transduction
1.57 1.46e-04 GO:0010468 regulation of gene expression
2.07 1.54e-04 GO:0031324 negative regulation of cellular metabolic process
1.63 1.55e-04 GO:0006355 regulation of transcription, DNA-dependent
1.55 1.85e-04 GO:0031326 regulation of cellular biosynthetic process
2.04 2.27e-04 GO:0010605 negative regulation of macromolecule metabolic process
3.31 2.91e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.54 3.56e-04 GO:0009889 regulation of biosynthetic process
1.76 9.25e-04 GO:0009966 regulation of signal transduction
2.16 1.23e-03 GO:0010628 positive regulation of gene expression
1.92 1.42e-03 GO:0009892 negative regulation of metabolic process
1.55 1.65e-03 GO:0048519 negative regulation of biological process
2.19 1.91e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.72 1.99e-03 GO:0009653 anatomical structure morphogenesis
1.38 2.34e-03 GO:0051716 cellular response to stimulus
1.52 3.00e-03 GO:0048522 positive regulation of cellular process
1.49 3.30e-03 GO:0048518 positive regulation of biological process
1.51 3.79e-03 GO:0044267 cellular protein metabolic process
1.80 3.98e-03 GO:0010604 positive regulation of macromolecule metabolic process
2.34 4.29e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.60 5.21e-03 GO:0048583 regulation of response to stimulus
2.09 5.23e-03 GO:0051254 positive regulation of RNA metabolic process
2.46 5.35e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.00 5.95e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.10 6.02e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.91 7.53e-03 GO:0006351 transcription, DNA-dependent
1.31 9.21e-03 GO:0043170 macromolecule metabolic process
1.70 9.60e-03 GO:0035556 intracellular signal transduction
1.98 1.03e-02 GO:2000026 regulation of multicellular organismal development
2.22 1.06e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.87 1.11e-02 GO:0050793 regulation of developmental process
1.94 1.36e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.96 1.78e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.70 1.90e-02 GO:0009893 positive regulation of metabolic process
2.19 2.54e-02 GO:0031175 neuron projection development
1.78 2.73e-02 GO:0006793 phosphorus metabolic process
1.78 2.73e-02 GO:0006796 phosphate metabolic process
1.24 3.36e-02 GO:0044237 cellular metabolic process
1.70 3.76e-02 GO:0031325 positive regulation of cellular metabolic process
1.62 3.90e-02 GO:0065009 regulation of molecular function

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 4.52e-10 GO:0005622 intracellular
1.19 4.31e-08 GO:0044424 intracellular part
1.38 2.80e-07 GO:0005634 nucleus
1.20 1.49e-05 GO:0043229 intracellular organelle
1.70 1.68e-05 GO:0031981 nuclear lumen
1.20 1.93e-05 GO:0043226 organelle
1.22 2.65e-05 GO:0043231 intracellular membrane-bounded organelle
1.22 3.07e-05 GO:0043227 membrane-bounded organelle
1.78 1.54e-04 GO:0005654 nucleoplasm
1.21 6.56e-04 GO:0005737 cytoplasm
1.54 7.96e-04 GO:0044428 nuclear part
1.47 1.56e-02 GO:0005829 cytosol
2.55 2.51e-02 GO:0000785 chromatin
1.06 2.57e-02 GO:0044464 cell part
1.06 2.61e-02 GO:0005623 cell
1.43 3.06e-02 GO:0070013 intracellular organelle lumen
1.38 3.08e-02 GO:0043228 non-membrane-bounded organelle
1.38 3.08e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.42 3.36e-02 GO:0031974 membrane-enclosed lumen
5.09 4.21e-02 GO:0017053 transcriptional repressor complex
1.41 4.28e-02 GO:0043233 organelle lumen
3.75 4.58e-02 GO:0000790 nuclear chromatin

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.33 1.16e-08 GO:0005515 protein binding
2.03 7.62e-06 GO:0030528 transcription regulator activity
2.91 2.98e-05 GO:0016563 transcription activator activity
2.53 4.66e-04 GO:0000988 protein binding transcription factor activity
2.53 4.66e-04 GO:0000989 transcription factor binding transcription factor activity
1.13 4.72e-04 GO:0005488 binding
2.46 1.23e-03 GO:0003712 transcription cofactor activity
2.17 1.66e-03 GO:0008092 cytoskeletal protein binding
3.47 1.83e-03 GO:0003714 transcription corepressor activity
2.65 1.83e-03 GO:0005083 small GTPase regulator activity
2.00 2.85e-03 GO:0043565 sequence-specific DNA binding
2.25 4.27e-03 GO:0019904 protein domain specific binding
2.52 4.72e-03 GO:0016564 transcription repressor activity
6.99 1.81e-02 GO:0005158 insulin receptor binding
1.72 2.17e-02 GO:0001071 nucleic acid binding transcription factor activity
1.72 2.17e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.08 2.73e-02 GO:0030695 GTPase regulator activity
2.02 4.54e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.44 4.80e-02 GO:0008270 zinc ion binding