Motif ID: AAUACUG

Z-value: 1.464


Mature miRNA associated with seed AAUACUG:

NamemiRBase Accession
hsa-miR-200b MIMAT0000318
hsa-miR-200c MIMAT0000617
hsa-miR-429 MIMAT0001536



Activity profile for motif AAUACUG.

activity profile for motif AAUACUG


Sorted Z-values histogram for motif AAUACUG

Sorted Z-values for motif AAUACUG



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUACUG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_31608097 2.866 NM_001174093
NM_001174095
NM_001174096
NM_030751
 ZEB1



zinc finger E-box binding homeobox 1



chr1_+_183605207 2.746 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr10_+_31610063 2.669 NM_001128128
NM_001174094
 ZEB1

zinc finger E-box binding homeobox 1

chr1_-_57045235 2.574 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_72748147 2.253 NM_173808
 NEGR1
neuronal growth regulator 1
chr8_-_12973752 2.004 NM_001164271
 DLC1
deleted in liver cancer 1
chr8_-_12990731 1.896 NM_006094
 DLC1
deleted in liver cancer 1
chr12_-_47219734 1.860 NM_001143824
NM_018018
 SLC38A4

solute carrier family 38, member 4

chr17_-_76921453 1.850 NM_003255
 TIMP2
TIMP metallopeptidase inhibitor 2
chr2_-_145277879 1.664 NM_001171653
NM_014795
 ZEB2

zinc finger E-box binding homeobox 2

chr2_-_175499275 1.630 NM_003387
 WIPF1
WAS/WASL interacting protein family, member 1
chr2_+_210288668 1.616 NM_001039538
 MAP2
microtubule-associated protein 2
chr2_-_175547471 1.596 NM_001077269
 WIPF1
WAS/WASL interacting protein family, member 1
chr2_+_210444364 1.587 NM_002374
NM_031845
NM_031847
 MAP2


microtubule-associated protein 2


chr10_-_81205091 1.572 NM_153367
 ZCCHC24
zinc finger, CCHC domain containing 24
chr13_-_33760215 1.558 NM_001243466
NM_178007
 STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33780142 1.463 NM_001243474
NM_052851
 STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33859835 1.423 NM_178006
 STARD13
StAR-related lipid transfer (START) domain containing 13
chr8_+_70405027 1.352 NM_001128205
NM_001128206
 SULF1

sulfatase 1

chr12_-_15942350 1.318 NM_004447
 EPS8
epidermal growth factor receptor pathway substrate 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 68 entries
enrichment   p-value GO term description
3.31 2.91e-04 GO:0048011 nerve growth factor receptor signaling pathway
2.66 2.18e-06 GO:0051253 negative regulation of RNA metabolic process
2.60 1.02e-05 GO:0045892 negative regulation of transcription, DNA-dependent
2.46 5.35e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.43 1.82e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.43 2.66e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.40 3.95e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
2.36 1.24e-04 GO:0010629 negative regulation of gene expression
2.34 4.29e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.32 4.17e-05 GO:0031327 negative regulation of cellular biosynthetic process
2.32 7.59e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
2.27 8.19e-05 GO:0009890 negative regulation of biosynthetic process
2.22 1.06e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.19 1.91e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.19 2.54e-02 GO:0031175 neuron projection development
2.16 1.23e-03 GO:0010628 positive regulation of gene expression
2.10 6.02e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.09 5.23e-03 GO:0051254 positive regulation of RNA metabolic process
2.07 4.35e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.07 1.54e-04 GO:0031324 negative regulation of cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
5.09 4.21e-02 GO:0017053 transcriptional repressor complex
3.75 4.58e-02 GO:0000790 nuclear chromatin
2.55 2.51e-02 GO:0000785 chromatin
1.78 1.54e-04 GO:0005654 nucleoplasm
1.70 1.68e-05 GO:0031981 nuclear lumen
1.54 7.96e-04 GO:0044428 nuclear part
1.47 1.56e-02 GO:0005829 cytosol
1.43 3.06e-02 GO:0070013 intracellular organelle lumen
1.42 3.36e-02 GO:0031974 membrane-enclosed lumen
1.41 4.28e-02 GO:0043233 organelle lumen
1.38 2.80e-07 GO:0005634 nucleus
1.38 3.08e-02 GO:0043228 non-membrane-bounded organelle
1.38 3.08e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.22 2.65e-05 GO:0043231 intracellular membrane-bounded organelle
1.22 3.07e-05 GO:0043227 membrane-bounded organelle
1.21 6.56e-04 GO:0005737 cytoplasm
1.20 4.52e-10 GO:0005622 intracellular
1.20 1.49e-05 GO:0043229 intracellular organelle
1.20 1.93e-05 GO:0043226 organelle
1.19 4.31e-08 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
6.99 1.81e-02 GO:0005158 insulin receptor binding
3.47 1.83e-03 GO:0003714 transcription corepressor activity
2.91 2.98e-05 GO:0016563 transcription activator activity
2.65 1.83e-03 GO:0005083 small GTPase regulator activity
2.53 4.66e-04 GO:0000988 protein binding transcription factor activity
2.53 4.66e-04 GO:0000989 transcription factor binding transcription factor activity
2.52 4.72e-03 GO:0016564 transcription repressor activity
2.46 1.23e-03 GO:0003712 transcription cofactor activity
2.25 4.27e-03 GO:0019904 protein domain specific binding
2.17 1.66e-03 GO:0008092 cytoskeletal protein binding
2.08 2.73e-02 GO:0030695 GTPase regulator activity
2.03 7.62e-06 GO:0030528 transcription regulator activity
2.02 4.54e-02 GO:0060589 nucleoside-triphosphatase regulator activity
2.00 2.85e-03 GO:0043565 sequence-specific DNA binding
1.72 2.17e-02 GO:0001071 nucleic acid binding transcription factor activity
1.72 2.17e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.44 4.80e-02 GO:0008270 zinc ion binding
1.33 1.16e-08 GO:0005515 protein binding
1.13 4.72e-04 GO:0005488 binding