Motif ID: AAUCUCA

Z-value: 0.088


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_207205996 0.038 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr8_-_57233240 0.037 NM_138969
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr5_-_148442606 0.029 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr5_+_68800003 0.027 NM_001205255
OCLN
occludin
chr5_+_68788118 0.027 NM_002538
OCLN
occludin
chr6_-_138428477 0.026 NM_022121
PERP
PERP, TP53 apoptosis effector
chr5_+_149109814 0.026 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr5_+_68788387 0.025 NM_001205254
OCLN
occludin
chr5_+_36608430 0.025 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_149151502 0.024 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr12_-_95044205 0.021 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr17_-_29641094 0.019 NM_006495
EVI2B
ecotropic viral integration site 2B
chr18_-_28622624 0.019 NM_001941
NM_024423
DSC3

desmocollin 3

chr1_-_53793743 0.018 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr1_-_160990971 0.018 NM_016946
F11R
F11 receptor
chr4_+_155665150 0.016 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr1_-_67520028 0.014 NM_015139
SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr12_+_5019048 0.012 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr2_+_113885137 0.012 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr3_+_142342265 0.012 NM_002670
PLS1
plastin 1
chr3_-_74570262 0.011 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr3_+_142375738 0.011 NM_001172312
PLS1
plastin 1
chr14_+_71374111 0.011 NM_014982
PCNX
pecanex homolog (Drosophila)
chr6_+_147829784 0.010 NM_001030060
SAMD5
sterile alpha motif domain containing 5
chr15_-_83953465 0.010 NM_001717
BNC1
basonuclin 1
chr10_-_116286661 0.010 NM_006720
ABLIM1
actin binding LIM protein 1
chr13_-_21476895 0.010 NM_022459
XPO4
exportin 4
chr11_-_17035948 0.010 NM_175058
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr21_-_43346780 0.009 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr17_+_53342320 0.009 NM_002126
HLF
hepatic leukemia factor
chr13_-_76055872 0.009 NM_014832
TBC1D4
TBC1 domain family, member 4
chr10_-_116418056 0.009 NM_002313
ABLIM1
actin binding LIM protein 1
chr10_-_116444374 0.009 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr3_+_142315205 0.009 NM_001145319
PLS1
plastin 1
chr21_-_43373938 0.009 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr19_+_45147090 0.008 NM_001135768
NM_001135769
NM_001135770
NM_006505
PVR



poliovirus receptor



chr5_+_36606456 0.008 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr12_-_12849120 0.008 NM_006143
GPR19
G protein-coupled receptor 19
chr17_-_26941178 0.008 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr9_+_4662285 0.008 NM_203453
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr8_+_67341244 0.008 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr22_-_46933066 0.008 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr22_-_19109912 0.007 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chr3_+_126707380 0.007 NM_032242
PLXNA1
plexin A1
chr9_-_36276930 0.007 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr7_-_139876718 0.007 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr2_+_26987122 0.007 NM_017877
CENPA
C2orf18
centromere protein A
chromosome 2 open reading frame 18
chr3_-_121264780 0.007 NM_199420
POLQ
polymerase (DNA directed), theta
chr14_-_104313730 0.007 NM_015316
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr4_+_3076236 0.007 NM_002111
HTT
huntingtin
chrX_+_105066531 0.006 NM_198465
NRK
Nik related kinase
chr2_-_203776948 0.006 NM_018256
WDR12
WD repeat domain 12
chr1_-_205782135 0.006 NM_173854
SLC41A1
solute carrier family 41, member 1
chr10_-_108924287 0.006 NM_001013031
NM_001206569
NM_001206570
NM_001206571
NM_001206572
NM_052918
SORCS1





sortilin-related VPS10 domain containing receptor 1





chr9_-_21031607 0.006 NM_001010915
PTPLAD2
protein tyrosine phosphatase-like A domain containing 2
chr1_-_109506016 0.006 NM_001048210
NM_015127
CLCC1

AKNAD1
chloride channel CLIC-like 1

AKNA domain containing 1
chr4_-_66535652 0.006 NM_004439
NM_182472
EPHA5

EPH receptor A5

chr12_+_11802726 0.006 NM_001987
ETV6
ets variant 6
chr2_+_113875469 0.006 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr8_-_110342107 0.006 NM_001128211
NUDCD1
NudC domain containing 1
chr4_+_89299874 0.006 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr7_-_91509979 0.006 NM_006980
MTERF
mitochondrial transcription termination factor
chr1_-_211307314 0.006 NM_002238
NM_172362
KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr8_-_110346272 0.006 NM_032869
NUDCD1
NudC domain containing 1
chr8_-_114449018 0.006 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr14_+_32798478 0.005 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr2_+_73441344 0.005 NM_006062
SMYD5
SMYD family member 5
chr2_+_135676387 0.005 NM_001241
NM_058241
CCNT2

cyclin T2

chr1_-_89738477 0.005 NM_001134486
NM_052942
GBP5

guanylate binding protein 5

chr17_+_48046561 0.005 NM_138281
DLX4
distal-less homeobox 4
chr1_-_204329043 0.005 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr8_-_114389381 0.005 NM_198124
CSMD3
CUB and Sushi multiple domains 3
chr9_+_87284573 0.005 NM_001018065
NM_001018066
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr4_+_81952118 0.005 NM_001201
BMP3
bone morphogenetic protein 3
chr3_-_121553907 0.005 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr9_-_36258383 0.005 NM_001190383
NM_001190384
NM_005476
GNE


glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase


chr10_+_98592015 0.005 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chrX_+_67718623 0.005 NM_001195214
NM_173834
YIPF6

Yip1 domain family, member 6

chr1_+_101361589 0.005 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr2_-_158485393 0.005 NM_001111032
NM_001111033
NM_145259
ACVR1C


activin A receptor, type IC


chr15_-_34629941 0.005 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr17_+_37793332 0.005 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr11_-_123065988 0.004 NM_024769
CLMP
CXADR-like membrane protein
chr19_+_42788605 0.004 NM_015125
CIC
capicua homolog (Drosophila)
chr16_-_10276115 0.004 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr15_-_49255640 0.004 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr21_+_36041687 0.004 NM_053277
CLIC6
chloride intracellular channel 6
chr15_-_34630203 0.004 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr10_+_11206928 0.004 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr2_+_234826042 0.004 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr9_-_14693459 0.004 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chr1_-_155532322 0.004 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr14_+_70078309 0.004 NM_014734
KIAA0247
KIAA0247
chr16_-_19729417 0.004 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr7_+_12250818 0.004 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr11_+_68228182 0.004 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chr11_-_128894008 0.004 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr2_-_151344145 0.004 NM_005168
RND3
Rho family GTPase 3
chr12_-_51420097 0.004 NM_000617
NM_001174126
NM_001174127
NM_001174128
SLC11A2



solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2



chr6_-_135271206 0.004 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr12_+_10163225 0.004 NM_001129998
NM_205852
CLEC12B

C-type lectin domain family 12, member B

chr12_-_57030083 0.004 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr4_-_139163222 0.003 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr18_-_22932109 0.003 NM_015461
ZNF521
zinc finger protein 521
chr10_+_43277953 0.003 NM_014753
BMS1
BMS1 homolog, ribosome assembly protein (yeast)
chr5_-_137549029 0.003 NM_004661
CDC23
cell division cycle 23 homolog (S. cerevisiae)
chr16_-_10912456 0.003 NM_001079512
FAM18A
family with sequence similarity 18, member A
chr18_+_59854514 0.003 NM_020854
KIAA1468
KIAA1468
chr10_+_46222647 0.003 NM_001169106
NM_001169107
NM_015262
FAM21C


family with sequence similarity 21, member C


chr12_+_27933162 0.003 NM_020782
KLHDC5
kelch domain containing 5
chr10_+_11047253 0.003 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr10_+_51827654 0.003 NM_001005751
FAM21C
FAM21A
family with sequence similarity 21, member C
family with sequence similarity 21, member A
chr16_-_10276610 0.003 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr11_-_129062092 0.003 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr2_-_158454025 0.003 NM_001111031
ACVR1C
activin A receptor, type IC
chr11_+_119076974 0.003 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr15_-_34610928 0.003 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_-_220445831 0.003 NM_012414
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr6_-_33048554 0.003 NM_001242524
NM_001242525
HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

chr13_-_31040035 0.003 NM_002128
HMGB1
high mobility group box 1
chrX_-_10588458 0.003 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr6_-_94129059 0.003 NM_004440
EPHA7
EPH receptor A7
chr12_-_10022457 0.003 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr7_-_113559048 0.003 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chrX_-_10645726 0.003 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr1_-_67896098 0.003 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr6_-_33041266 0.003 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr4_+_148402068 0.003 NM_001166055
NM_001957
EDNRA

endothelin receptor type A

chr2_+_203241044 0.003 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr1_-_6296034 0.003 NM_012405
ICMT
isoprenylcysteine carboxyl methyltransferase
chr15_-_34629044 0.002 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr18_-_61034350 0.002 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr11_-_69490093 0.002 NM_153451
ORAOV1
oral cancer overexpressed 1
chr3_+_42642105 0.002 NM_005385
NKTR
natural killer-tumor recognition sequence
chr16_-_18937722 0.002 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr13_-_73356070 0.002 NM_001128226
NM_014953
DIS3

DIS3 mitotic control homolog (S. cerevisiae)

chr16_-_67840464 0.002 NM_020850
RANBP10
RAN binding protein 10
chr1_+_33938231 0.002 NM_145238
ZSCAN20
zinc finger and SCAN domain containing 20
chr16_+_31191430 0.002 NM_001170634
NM_001170937
NM_004960
FUS


fused in sarcoma


chr4_+_40058507 0.002 NM_018177
N4BP2
NEDD4 binding protein 2
chrX_-_10544852 0.002 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr17_-_62340652 0.002 NM_018469
TEX2
testis expressed 2
chr5_-_34043234 0.002 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr4_-_113437327 0.002 NM_024019
NEUROG2
neurogenin 2
chrX_-_10851808 0.002 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr17_+_30677138 0.002 NM_001032293
NM_001098507
NM_003457
ZNF207


zinc finger protein 207


chr9_-_104500861 0.002 NM_133445
GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr10_+_98592658 0.002 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr4_-_85887543 0.002 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chr1_+_166808721 0.002 NM_017542
POGK
pogo transposable element with KRAB domain
chr4_+_99916787 0.002 NM_015143
METAP1
methionyl aminopeptidase 1
chr3_+_63638343 0.002 NM_001080537
SNTN
sentan, cilia apical structure protein
chr15_-_33360084 0.002 NM_001103184
FMN1
formin 1
chr11_+_92085261 0.002 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr20_-_524335 0.002 NM_001895
NM_177559
NM_177560
CSNK2A1


casein kinase 2, alpha 1 polypeptide


chr1_-_220263150 0.002 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chrX_+_122993536 0.002 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr4_-_121993568 0.002 NM_024574
NDNF
neuron-derived neurotrophic factor
chr11_-_132812870 0.002 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr16_-_12009804 0.002 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr3_-_69129502 0.002 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr10_+_11059854 0.002 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr3_+_172472246 0.002 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr3_+_19189969 0.002 NM_144633
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr1_-_52831817 0.002 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr2_-_26205437 0.001 NM_002254
KIF3C
kinesin family member 3C
chr5_+_139493689 0.001 NM_005859
PURA
purine-rich element binding protein A
chrX_-_30907408 0.001 NM_152787
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr8_+_48872762 0.001 NM_005914
NM_182746
MCM4

minichromosome maintenance complex component 4

chr15_-_65321921 0.001 NM_139242
MTFMT
mitochondrial methionyl-tRNA formyltransferase
chr15_+_22833394 0.001 NM_001102610
NM_052903
TUBGCP5

tubulin, gamma complex associated protein 5

chr13_-_100624162 0.001 NM_033132
ZIC5
Zic family member 5
chr2_-_228029274 0.001 NM_000092
COL4A4
collagen, type IV, alpha 4
chrX_-_19905665 0.001 NM_031892
SH3KBP1
SH3-domain kinase binding protein 1
chr9_-_14779530 0.001 NM_001177704
FREM1
FRAS1 related extracellular matrix 1
chr3_+_85775631 0.001 NM_153184
CADM2
cell adhesion molecule 2
chr12_+_106994914 0.001 NM_001206691
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chrX_-_19688991 0.001 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_154155698 0.001 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chr2_-_172967234 0.001 NM_004405
DLX2
distal-less homeobox 2
chrX_-_20284708 0.001 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr19_+_54041332 0.001 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr9_-_14910992 0.001 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr3_-_160283361 0.001 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr8_-_89339716 0.001 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr1_+_14075861 0.001 NM_001007257
PRDM2
PR domain containing 2, with ZNF domain
chr14_+_73603140 0.001 NM_000021
NM_007318
PSEN1

presenilin 1

chr18_-_67624159 0.001 NM_006566
CD226
CD226 molecule
chr1_+_27719151 0.001 NM_005281
GPR3
G protein-coupled receptor 3
chr16_-_12010518 0.001 NM_001130007
GSPT1
G1 to S phase transition 1
chrX_-_19817907 0.001 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr18_+_67068134 0.001 NM_152721
DOK6
docking protein 6
chr11_+_108093558 0.001 NM_000051
ATM
ataxia telangiectasia mutated
chr18_-_24442534 0.001 NM_004028
AQP4
aquaporin 4
chr6_+_97372495 0.001 NM_052904
KLHL32
kelch-like 32 (Drosophila)
chrX_+_144899330 0.001 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chr4_+_76649826 0.001 NM_003715
USO1
USO1 vesicle docking protein homolog (yeast)
chr3_-_142166782 0.001 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr9_+_71650478 0.001 NM_000144
NM_001161706
NM_181425
FXN


frataxin


chr12_+_106976684 0.001 NM_213594
RFX4
regulatory factor X, 4 (influences HLA class II expression)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.85 1.19e-02 GO:0044459 plasma membrane part

Nothing significant found in function category.