Motif ID: AAUGCCC

Z-value: 0.490


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365 MIMAT0000710



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_149109814 0.222 NM_001172698
NM_133263
 PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr5_+_149151502 0.220 NM_001172699
 PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_-_153588789 0.206 NM_020672
 S100A14
S100 calcium binding protein A14
chr11_+_34654010 0.162 NM_001206616
 EHF
ets homologous factor
chr12_+_72666462 0.159 NM_013381
 TRHDE
thyrotropin-releasing hormone degrading enzyme
chr8_+_28351694 0.158 NM_017412
NM_145866
 FZD3

frizzled family receptor 3

chr11_+_34642587 0.150 NM_001206615
NM_012153
 EHF

ets homologous factor

chr3_-_123339423 0.137 NM_053031
NM_053032
 MYLK

myosin light chain kinase

chr13_-_21476895 0.126 NM_022459
 XPO4
exportin 4
chr10_-_105614952 0.120 NM_014631
 SH3PXD2A
SH3 and PX domains 2A
chr3_-_123603144 0.115 NM_053025
NM_053026
NM_053027
NM_053028
 MYLK



myosin light chain kinase



chr8_-_127570710 0.097 NM_174911
 FAM84B
family with sequence similarity 84, member B
chr9_-_23826062 0.089 NM_004432
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_83824216 0.087 NM_006080
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_48229800 0.082 NM_001789
NM_201567
 CDC25A

cell division cycle 25 homolog A (S. pombe)

chr12_+_5019048 0.080 NM_000217
 KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chrX_+_37545008 0.079 NM_021083
 XK
X-linked Kx blood group (McLeod syndrome)
chr9_-_23821477 0.079 NM_001171197
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_85462622 0.078 NM_153259
 MCOLN2
mucolipin 2
chr3_+_189507448 0.077 NM_001114980
NM_001114981
NM_001114982
 TP63


tumor protein p63



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
4.22 1.57e-02 GO:0043193 positive regulation of gene-specific transcription
3.80 6.30e-03 GO:0006366 transcription from RNA polymerase II promoter
3.69 1.27e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
3.61 2.62e-04 GO:0032583 regulation of gene-specific transcription
3.48 3.33e-06 GO:0045893 positive regulation of transcription, DNA-dependent
3.46 1.09e-06 GO:0051254 positive regulation of RNA metabolic process
3.43 1.40e-06 GO:0010628 positive regulation of gene expression
3.24 1.70e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.21 4.10e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
3.18 3.73e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.15 3.68e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
3.14 4.22e-07 GO:0006351 transcription, DNA-dependent
3.02 6.06e-06 GO:0031328 positive regulation of cellular biosynthetic process
2.97 9.36e-06 GO:0009891 positive regulation of biosynthetic process
2.83 7.41e-06 GO:0032774 RNA biosynthetic process
2.67 8.52e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.57 2.66e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.48 3.45e-05 GO:0009893 positive regulation of metabolic process
2.44 1.67e-04 GO:0031325 positive regulation of cellular metabolic process
2.14 3.02e-04 GO:0034645 cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
5.57 4.66e-02 GO:0000790 nuclear chromatin
2.41 8.70e-03 GO:0044451 nucleoplasm part
2.29 5.30e-05 GO:0005654 nucleoplasm
1.96 3.69e-04 GO:0031981 nuclear lumen
1.73 6.04e-03 GO:0070013 intracellular organelle lumen
1.73 8.31e-03 GO:0044428 nuclear part
1.69 1.05e-02 GO:0043233 organelle lumen
1.67 1.63e-02 GO:0031974 membrane-enclosed lumen
1.37 1.85e-02 GO:0005634 nucleus
1.21 3.60e-02 GO:0043229 intracellular organelle
1.20 4.04e-02 GO:0043226 organelle
1.19 3.04e-03 GO:0044424 intracellular part
1.17 1.63e-02 GO:0005622 intracellular
1.11 9.75e-04 GO:0044464 cell part
1.11 9.86e-04 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
5.80 1.73e-02 GO:0003704 specific RNA polymerase II transcription factor activity
3.98 1.53e-03 GO:0003702 RNA polymerase II transcription factor activity
3.88 1.67e-02 GO:0000975 regulatory region DNA binding
3.88 1.67e-02 GO:0001067 regulatory region nucleic acid binding
3.88 1.67e-02 GO:0044212 transcription regulatory region DNA binding
3.86 3.47e-02 GO:0003682 chromatin binding
3.81 3.33e-04 GO:0016563 transcription activator activity
3.20 3.41e-02 GO:0008134 transcription factor binding
2.94 5.21e-05 GO:0043565 sequence-specific DNA binding
2.74 2.45e-06 GO:0001071 nucleic acid binding transcription factor activity
2.74 2.45e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
2.61 1.46e-05 GO:0030528 transcription regulator activity
1.80 9.04e-04 GO:0003677 DNA binding
1.56 8.66e-03 GO:0003676 nucleic acid binding
1.42 8.74e-06 GO:0005515 protein binding
1.17 7.25e-03 GO:0005488 binding