Motif ID: AAUGCCC

Z-value: 0.490


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365 MIMAT0000710



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_149109814 0.222 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr5_+_149151502 0.220 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_-_153588789 0.206 NM_020672
S100A14
S100 calcium binding protein A14
chr11_+_34654010 0.162 NM_001206616
EHF
ets homologous factor
chr12_+_72666462 0.159 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr8_+_28351694 0.158 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr11_+_34642587 0.150 NM_001206615
NM_012153
EHF

ets homologous factor

chr3_-_123339423 0.137 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr13_-_21476895 0.126 NM_022459
XPO4
exportin 4
chr10_-_105614952 0.120 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr3_-_123603144 0.115 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr8_-_127570710 0.097 NM_174911
FAM84B
family with sequence similarity 84, member B
chr9_-_23826062 0.089 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_83824216 0.087 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_48229800 0.082 NM_001789
NM_201567
CDC25A

cell division cycle 25 homolog A (S. pombe)

chr12_+_5019048 0.080 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chrX_+_37545008 0.079 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr9_-_23821477 0.079 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_85462622 0.078 NM_153259
MCOLN2
mucolipin 2
chr3_+_189507448 0.077 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr14_-_99737821 0.077 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr9_-_23821842 0.076 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_-_125648704 0.075 NM_212555
PATE2
prostate and testis expressed 2
chr2_-_208634051 0.074 NM_003468
FZD5
frizzled family receptor 5
chr12_-_67072881 0.074 NM_001178074
NM_021150
GRIP1

glutamate receptor interacting protein 1

chr11_+_128563772 0.073 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chr3_+_189349215 0.073 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr8_+_120220554 0.072 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr8_+_124780742 0.069 NM_144963
FAM91A1
family with sequence similarity 91, member A1
chr20_+_9198036 0.066 NM_182797
PLCB4
phospholipase C, beta 4
chr7_+_97736118 0.066 NM_014916
LMTK2
lemur tyrosine kinase 2
chr1_-_38273852 0.066 NM_024640
YRDC
yrdC domain containing (E. coli)
chr20_+_9288446 0.065 NM_000933
PLCB4
phospholipase C, beta 4
chr5_-_64777703 0.064 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr20_+_9049660 0.064 NM_001172646
PLCB4
phospholipase C, beta 4
chr1_+_95558072 0.063 NM_001199679
TMEM56
transmembrane protein 56
chr4_-_11430502 0.063 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr8_+_1449531 0.063 NM_004745
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr9_-_117156684 0.062 NM_030767
AKNA
AT-hook transcription factor
chr2_-_153573858 0.062 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr11_+_63606346 0.062 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr3_+_124303505 0.062 NM_007064
KALRN
kalirin, RhoGEF kinase
chr11_+_63655986 0.061 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr10_-_103874661 0.059 NM_003893
LDB1
LIM domain binding 1
chr1_+_95582827 0.057 NM_152487
TMEM56
transmembrane protein 56
chr3_-_194188967 0.056 NM_024524
ATP13A3
ATPase type 13A3
chr12_-_31479120 0.055 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr17_-_56565700 0.054 NM_001080439
HSF5
heat shock transcription factor family member 5
chr15_+_75074417 0.053 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr2_-_142889269 0.053 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr3_+_14989076 0.052 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr17_-_48072566 0.051 NM_005220
DLX3
distal-less homeobox 3
chr12_-_8088629 0.051 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr17_+_38119225 0.049 NM_178171
GSDMA
gasdermin A
chr18_+_43753986 0.049 NM_001008239
NM_145055
C18orf25

chromosome 18 open reading frame 25

chr10_+_101419169 0.047 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr5_-_142065586 0.047 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr3_+_113775580 0.047 NM_024638
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr9_+_128024109 0.047 NM_015635
GAPVD1
GTPase activating protein and VPS9 domains 1
chr3_-_9005070 0.046 NM_020165
RAD18
RAD18 homolog (S. cerevisiae)
chr5_-_142065991 0.046 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr10_-_103879933 0.046 NM_001113407
LDB1
LIM domain binding 1
chr17_-_56494930 0.046 NM_017763
RNF43
ring finger protein 43
chr13_-_46425756 0.044 NM_198849
SIAH3
seven in absentia homolog 3 (Drosophila)
chr12_+_83080901 0.044 NM_152588
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chrX_+_77359665 0.044 NM_000291
PGK1
phosphoglycerate kinase 1
chr3_-_113465101 0.043 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr5_-_142000899 0.043 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr8_-_57906423 0.042 NM_017813
IMPAD1
inositol monophosphatase domain containing 1
chr3_+_150804675 0.042 NM_053002
MED12L
mediator complex subunit 12-like
chr11_+_35160385 0.042 NM_000610
NM_001001389
NM_001001390
NM_001001391
NM_001001392
NM_001202555
NM_001202556
NM_001202557
CD44







CD44 molecule (Indian blood group)







chr5_-_142077508 0.041 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chrX_+_69664704 0.041 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr4_-_40517913 0.041 NM_019027
RBM47
RNA binding motif protein 47
chr10_-_61900659 0.040 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_-_42419782 0.040 NM_033502
TRERF1
transcriptional regulating factor 1
chr5_-_141993691 0.040 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr10_-_62149487 0.039 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_74124456 0.039 NM_032217
NM_198889
ANKRD17

ankyrin repeat domain 17

chr17_-_40273304 0.039 NM_021078
KAT2A
K(lysine) acetyltransferase 2A
chr6_-_3456734 0.039 NM_015482
SLC22A23
solute carrier family 22, member 23
chrX_-_30907408 0.039 NM_152787
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_-_62332666 0.039 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr5_+_148651395 0.038 NM_001146337
NM_152406
AFAP1L1

actin filament associated protein 1-like 1

chr22_+_37309618 0.038 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_+_155051263 0.037 NM_004952
EFNA3
ephrin-A3
chr1_+_2985730 0.036 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr14_-_36988902 0.035 NM_003317
NKX2-1
NK2 homeobox 1
chrX_+_147582133 0.035 NM_001169122
NM_001169123
NM_001169124
NM_001169125
NM_002025
AFF2




AF4/FMR2 family, member 2




chr19_-_47975244 0.034 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr11_+_111895537 0.034 NM_001931
DLAT
dihydrolipoamide S-acetyltransferase
chr14_-_36989333 0.034 NM_001079668
NKX2-1
NK2 homeobox 1
chr15_+_52121807 0.034 NM_014547
TMOD3
tropomodulin 3 (ubiquitous)
chr3_+_14444083 0.034 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr6_+_106534188 0.033 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chrX_+_69674914 0.033 NM_001166278
DLG3
discs, large homolog 3 (Drosophila)
chrX_+_69672110 0.033 NM_020730
DLG3
discs, large homolog 3 (Drosophila)
chr20_-_62284701 0.033 NM_015894
STMN3
stathmin-like 3
chr6_+_106546736 0.032 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr2_+_48541767 0.032 NM_002158
FOXN2
forkhead box N2
chr22_+_40573879 0.032 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chrX_+_147800610 0.032 NM_001170628
AFF2
AF4/FMR2 family, member 2
chr17_-_17399494 0.032 NM_001199989
NM_016084
RASD1

RAS, dexamethasone-induced 1

chr9_-_14314036 0.032 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr12_-_81763127 0.031 NM_001220479
NM_001220480
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr12_-_123594974 0.031 NM_020845
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr4_+_38665587 0.031 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr17_-_38574042 0.031 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr3_-_47823386 0.030 NM_003074
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr1_-_23857711 0.030 NM_004091
E2F2
E2F transcription factor 2
chr11_+_64073040 0.030 NM_004451
ESRRA
estrogen-related receptor alpha
chr8_-_20112691 0.029 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chr6_-_3445198 0.029 NM_021945
SLC22A23
solute carrier family 22, member 23
chr5_+_148724976 0.029 NM_152407
GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr5_-_132073143 0.028 NM_007054
KIF3A
kinesin family member 3A
chr11_-_128392061 0.028 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chrX_-_15353675 0.028 NM_002641
NM_020473
PIGA

phosphatidylinositol glycan anchor biosynthesis, class A

chr6_+_131456825 0.027 NM_016377
AKAP7
A kinase (PRKA) anchor protein 7
chr12_+_98909331 0.027 NM_001032283
NM_001032284
NM_003276
TMPO


thymopoietin


chr2_-_64881040 0.026 NM_014755
SERTAD2
SERTA domain containing 2
chr12_-_118406027 0.026 NM_173598
KSR2
kinase suppressor of ras 2
chr4_-_40631846 0.026 NM_001098634
RBM47
RNA binding motif protein 47
chr4_+_91048683 0.026 NM_001145065
FAM190A
family with sequence similarity 190, member A
chr11_-_128457452 0.026 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr3_-_15798057 0.025 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr12_-_42538432 0.025 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr14_-_88737160 0.025 NM_138318
KCNK10
potassium channel, subfamily K, member 10
chr12_-_81991959 0.025 NM_001220477
NM_001220478
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr5_+_74632992 0.025 NM_000859
NM_001130996
HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

chr14_-_88793250 0.025 NM_021161
KCNK10
potassium channel, subfamily K, member 10
chr12_-_82152269 0.025 NM_001220475
NM_001220476
NM_001220473
NM_001220474
PPFIA2



protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2



chr5_-_39074494 0.024 NM_152756
RICTOR
RPTOR independent companion of MTOR, complex 2
chr10_+_16478941 0.024 NM_001001484
NM_030664
PTER

phosphotriesterase related

chr22_+_21271619 0.024 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr19_+_50094911 0.023 NM_020719
PRR12
proline rich 12
chr3_+_50229022 0.023 NM_000172
NM_144499
GNAT1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

chr10_-_62493282 0.023 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_-_156051788 0.023 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr12_+_124118312 0.023 NM_001516
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa
chr17_-_27621163 0.023 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr6_+_80340971 0.022 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr5_-_168006413 0.022 NM_024594
PANK3
pantothenate kinase 3
chr22_+_32340435 0.022 NM_003405
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr12_-_82153092 0.022 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr10_-_32217762 0.022 NM_018287
ARHGAP12
Rho GTPase activating protein 12
chr8_+_54793409 0.021 NM_003702
RGS20
regulator of G-protein signaling 20
chr14_-_68162419 0.021 NM_001252650
NM_016026
RDH11

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

chr12_-_49449106 0.021 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr11_+_68816314 0.021 NM_139075
TPCN2
two pore segment channel 2
chr11_-_122932844 0.021 NM_006597
NM_153201
HSPA8

heat shock 70kDa protein 8

chr14_-_88789531 0.021 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr17_+_38444134 0.021 NM_001254
CDC6
cell division cycle 6 homolog (S. cerevisiae)
chr17_-_42275425 0.021 NM_001098833
NM_020218
ATXN7L3

ataxin 7-like 3

chr11_-_27528298 0.021 NM_018362
LIN7C
lin-7 homolog C (C. elegans)
chr11_-_16424391 0.020 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr22_+_40440664 0.020 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr13_+_30002776 0.020 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr7_+_141251077 0.020 NM_018238
AGK
acylglycerol kinase
chr3_-_125094003 0.020 NM_021964
ZNF148
zinc finger protein 148
chr6_-_88411984 0.019 NM_018064
AKIRIN2
akirin 2
chr10_-_120514669 0.019 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr10_-_103815868 0.019 NM_024541
C10orf76
chromosome 10 open reading frame 76
chr1_+_157963062 0.019 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr2_-_206950895 0.019 NM_017759
INO80D
INO80 complex subunit D
chr19_-_42636559 0.018 NM_001207025
NM_001207026
NM_001247994
NM_002698
POU2F2



POU class 2 homeobox 2



chr11_+_69455837 0.018 NM_053056
CCND1
cyclin D1
chr1_+_61547388 0.018 NM_001145512
NFIA
nuclear factor I/A
chr22_+_42229105 0.018 NM_004599
SREBF2
sterol regulatory element binding transcription factor 2
chr1_+_236958539 0.018 NM_000254
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chr3_+_43328001 0.017 NM_001100594
NM_017719
SNRK

SNF related kinase

chr6_+_34857021 0.017 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr12_-_89918531 0.017 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr11_+_107461807 0.017 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr16_-_67840464 0.017 NM_020850
RANBP10
RAN binding protein 10
chr10_-_735522 0.016 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr4_-_149363498 0.016 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr3_-_125314367 0.016 NM_022776
OSBPL11
oxysterol binding protein-like 11
chr11_-_16497917 0.016 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr12_+_66218141 0.015 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr18_+_32397925 0.015 NM_001198943
DTNA
dystrobrevin, alpha
chr16_+_19422056 0.015 NM_001105248
NM_001105249
TMC5

transmembrane channel-like 5

chr2_+_183580960 0.015 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr9_+_131445933 0.015 NM_001122821
SET
SET nuclear oncogene
chrX_+_73641084 0.015 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr5_-_79286793 0.015 NM_001010891
NM_001167741
MTX3

metaxin 3

chr7_+_4721722 0.015 NM_001037165
FOXK1
forkhead box K1
chr13_+_29598746 0.014 NM_001033602
MTUS2
microtubule associated tumor suppressor candidate 2
chr2_+_192542860 0.014 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr6_+_131571298 0.014 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr9_+_116638544 0.014 NM_133374
ZNF618
zinc finger protein 618
chr10_-_101190201 0.014 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr8_-_41909477 0.014 NM_001099412
NM_001099413
NM_006766
KAT6A


K(lysine) acetyltransferase 6A


chr2_-_183731279 0.014 NM_001463
FRZB
frizzled-related protein
chr12_-_70093064 0.013 NM_032735
BEST3
bestrophin 3
chr12_+_2162388 0.013 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr8_+_67624652 0.013 NM_001033578
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr14_+_52734430 0.013 NM_000953
PTGDR
prostaglandin D2 receptor (DP)
chr2_-_136594749 0.013 NM_002299
LCT
lactase
chr18_+_32398225 0.013 NM_001198942
NM_001198944
NM_032980
NM_032981
DTNA



dystrobrevin, alpha



chr8_+_54764367 0.012 NM_170587
RGS20
regulator of G-protein signaling 20

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.14 4.22e-07 GO:0006351 transcription, DNA-dependent
3.46 1.09e-06 GO:0051254 positive regulation of RNA metabolic process
3.43 1.40e-06 GO:0010628 positive regulation of gene expression
3.24 1.70e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.48 3.33e-06 GO:0045893 positive regulation of transcription, DNA-dependent
3.15 3.68e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
3.21 4.10e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
3.02 6.06e-06 GO:0031328 positive regulation of cellular biosynthetic process
2.83 7.41e-06 GO:0032774 RNA biosynthetic process
2.97 9.36e-06 GO:0009891 positive regulation of biosynthetic process
2.02 1.14e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.57 2.66e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.97 3.25e-05 GO:0010556 regulation of macromolecule biosynthetic process
2.48 3.45e-05 GO:0009893 positive regulation of metabolic process
1.75 4.49e-05 GO:0031323 regulation of cellular metabolic process
1.99 7.49e-05 GO:0051252 regulation of RNA metabolic process
2.67 8.52e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.91 1.03e-04 GO:0010468 regulation of gene expression
1.68 1.04e-04 GO:0019222 regulation of metabolic process
1.76 1.05e-04 GO:0060255 regulation of macromolecule metabolic process
1.88 1.07e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 1.07e-04 GO:0031326 regulation of cellular biosynthetic process
2.00 1.08e-04 GO:0006355 regulation of transcription, DNA-dependent
1.85 1.54e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.86 1.65e-04 GO:0009889 regulation of biosynthetic process
2.44 1.67e-04 GO:0031325 positive regulation of cellular metabolic process
1.71 2.34e-04 GO:0080090 regulation of primary metabolic process
3.61 2.62e-04 GO:0032583 regulation of gene-specific transcription
2.14 3.02e-04 GO:0034645 cellular macromolecule biosynthetic process
2.12 4.31e-04 GO:0009059 macromolecule biosynthetic process
3.69 1.27e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.85 1.43e-03 GO:0044249 cellular biosynthetic process
3.18 3.73e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.85 4.22e-03 GO:0090304 nucleic acid metabolic process
1.77 5.97e-03 GO:0009058 biosynthetic process
3.80 6.30e-03 GO:0006366 transcription from RNA polymerase II promoter
4.22 1.57e-02 GO:0043193 positive regulation of gene-specific transcription
1.90 2.53e-02 GO:0016070 RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.29 5.30e-05 GO:0005654 nucleoplasm
1.96 3.69e-04 GO:0031981 nuclear lumen
1.11 9.75e-04 GO:0044464 cell part
1.11 9.86e-04 GO:0005623 cell
1.19 3.04e-03 GO:0044424 intracellular part
1.73 6.04e-03 GO:0070013 intracellular organelle lumen
1.73 8.31e-03 GO:0044428 nuclear part
2.41 8.70e-03 GO:0044451 nucleoplasm part
1.69 1.05e-02 GO:0043233 organelle lumen
1.17 1.63e-02 GO:0005622 intracellular
1.67 1.63e-02 GO:0031974 membrane-enclosed lumen
1.37 1.85e-02 GO:0005634 nucleus
1.21 3.60e-02 GO:0043229 intracellular organelle
1.20 4.04e-02 GO:0043226 organelle
5.57 4.66e-02 GO:0000790 nuclear chromatin

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.74 2.45e-06 GO:0001071 nucleic acid binding transcription factor activity
2.74 2.45e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.42 8.74e-06 GO:0005515 protein binding
2.61 1.46e-05 GO:0030528 transcription regulator activity
2.94 5.21e-05 GO:0043565 sequence-specific DNA binding
3.81 3.33e-04 GO:0016563 transcription activator activity
1.80 9.04e-04 GO:0003677 DNA binding
3.98 1.53e-03 GO:0003702 RNA polymerase II transcription factor activity
1.17 7.25e-03 GO:0005488 binding
1.56 8.66e-03 GO:0003676 nucleic acid binding
3.88 1.67e-02 GO:0000975 regulatory region DNA binding
3.88 1.67e-02 GO:0001067 regulatory region nucleic acid binding
3.88 1.67e-02 GO:0044212 transcription regulatory region DNA binding
5.80 1.73e-02 GO:0003704 specific RNA polymerase II transcription factor activity
3.20 3.41e-02 GO:0008134 transcription factor binding
3.86 3.47e-02 GO:0003682 chromatin binding