Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 1.796


Transcription factors associated with ADNP_IRX_SIX_ZHX.p2:

Gene SymbolEntrez IDGene Name
ADNP 23394 activity-dependent neuroprotector homeobox
IRX4 50805 iroquois homeobox 4
IRX5 10265 iroquois homeobox 5
SIX2 10736 SIX homeobox 2
SIX5 147912 SIX homeobox 5
ZHX1 11244 zinc fingers and homeoboxes 1
ZHX2 22882 zinc fingers and homeoboxes 2
ZHX3 23051 zinc fingers and homeoboxes 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZHX1chr8_-_124286566-0.921.2e-03Click!
ZHX3chr20_-_399287080.911.8e-03Click!
IRX4chr5_-_1882764-0.866.4e-03Click!
SIX2chr2_-_452365210.733.8e-02Click!
ZHX2chr8_+_123793988,
chr8_+_123794043		-0.667.4e-02Click!
IRX5chr16_+_549651100.157.2e-01Click!
ADNPchr20_-_495474510.127.9e-01Click!
SIX5chr19_-_462724960.059.1e-01Click!


Activity profile for motif ADNP_IRX_SIX_ZHX.p2.

activity profile for motif ADNP_IRX_SIX_ZHX.p2


Sorted Z-values histogram for motif ADNP_IRX_SIX_ZHX.p2

Sorted Z-values for motif ADNP_IRX_SIX_ZHX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ADNP_IRX_SIX_ZHX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_102104941 5.194 NM_004791
 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr5_-_111312522 3.077 NM_001142474
NM_001142475
 C5orf13

chromosome 5 open reading frame 13

chr5_+_156696351 2.992 NM_014376
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_-_91576579 2.847 DCN
decorin
chr12_-_91576805 2.804 NM_001920
 DCN
decorin
chrX_+_85517970 2.726 NM_001139515
 DACH2
dachshund homolog 2 (Drosophila)
chr2_+_189839132 2.301 COL3A1
collagen, type III, alpha 1
chr9_-_95186559 2.216 NM_005014
 OMD
osteomodulin
chr3_+_69812961 2.167 NM_006722
 MITF
microphthalmia-associated transcription factor
chr4_+_70916158 2.034 NM_002159
 HTN1
histatin 1
chr5_+_71403040 1.979 NM_005909
 MAP1B
microtubule-associated protein 1B
chr5_+_71502700 1.940 MAP1B
microtubule-associated protein 1B
chr1_+_78470593 1.912 NM_007034
 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_+_110407389 1.884 NM_033035
 TSLP
thymic stromal lymphopoietin
chr3_-_112358510 1.853 CCDC80
coiled-coil domain containing 80
chr1_+_115572414 1.849 NM_000549
 TSHB
thyroid stimulating hormone, beta
chr5_-_168271852 1.641


chr2_-_200325200 1.634 SATB2
SATB homeobox 2
chr20_-_34025955 1.625 NM_000557
 GDF5
growth differentiation factor 5
chr5_+_95066628 1.621 NM_014899
 RHOBTB3
Rho-related BTB domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.68 8.11e-03 GO:0007156 homophilic cell adhesion
1.37 4.46e-03 GO:0006355 regulation of transcription, DNA-dependent
1.34 6.50e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.34 6.85e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.34 1.73e-02 GO:0051252 regulation of RNA metabolic process
1.32 1.19e-02 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.47 1.71e-02 GO:0044421 extracellular region part
1.37 1.04e-03 GO:0005576 extracellular region

Nothing significant found in function category.