Motif ID: AGCACCA

Z-value: 2.091


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
hsa-miR-29a MIMAT0000086
hsa-miR-29b MIMAT0000100
hsa-miR-29c MIMAT0000681



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_189839078 6.024 NM_000090
 COL3A1
collagen, type III, alpha 1
chr7_+_94023872 4.834 NM_000089
 COL1A2
collagen, type I, alpha 2
chr15_-_48937795 4.568 NM_000138
 FBN1
fibrillin 1
chr1_-_236228476 4.288 NM_002508
 NID1
nidogen 1
chrX_+_16964730 3.490 NM_001080975
NM_004726
 REPS2

RALBP1 associated Eps domain containing 2

chr2_+_109745996 3.241 NM_001099289
 SH3RF3
SH3 domain containing ring finger 3
chr3_+_157154579 3.179 NM_002852
 PTX3
pentraxin 3, long
chr5_-_111312522 3.128 NM_001142474
NM_001142475
 C5orf13

chromosome 5 open reading frame 13

chr5_-_111093251 3.082 NM_001142479
NM_001142480
NM_001142478
 C5orf13


chromosome 5 open reading frame 13


chr5_-_111093030 3.075 NM_001142482
NM_001142481
 C5orf13

chromosome 5 open reading frame 13

chr5_-_111093792 3.049 NM_001142477
NM_001142476
 C5orf13

chromosome 5 open reading frame 13

chr5_-_111092918 3.032 NM_004772
 C5orf13
chromosome 5 open reading frame 13
chr6_-_88875766 2.999 NM_001160226
NM_001160258
NM_001160259
NM_016083
 CNR1



cannabinoid receptor 1 (brain)



chr10_-_21463019 2.913 NM_001173484
NM_213569
 NEBL

nebulette

chr5_-_149535420 2.731 NM_002609
 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr17_-_48278987 2.653 NM_000088
 COL1A1
collagen, type I, alpha 1
chr1_-_3528058 2.597 NM_001409
 MEGF6
multiple EGF-like-domains 6
chr2_-_190044330 2.573 NM_000393
 COL5A2
collagen, type V, alpha 2
chr16_+_55515468 2.539 NM_001127891
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr16_+_55512801 2.407 NM_004530
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
29.32 2.28e-03 GO:0032964 collagen biosynthetic process
10.86 1.73e-05 GO:0030199 collagen fibril organization
8.38 5.15e-03 GO:0043588 skin development
4.99 1.91e-04 GO:0030198 extracellular matrix organization
2.29 8.93e-03 GO:0031175 neuron projection development
2.24 1.01e-03 GO:0030030 cell projection organization
2.20 6.61e-03 GO:0048666 neuron development
2.16 7.18e-05 GO:0048699 generation of neurons
2.11 9.70e-05 GO:0022008 neurogenesis
2.06 9.80e-03 GO:0030182 neuron differentiation
2.03 4.49e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.00 2.96e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.96 4.84e-02 GO:0009890 negative regulation of biosynthetic process
1.86 2.45e-02 GO:0050793 regulation of developmental process
1.82 1.76e-04 GO:0007399 nervous system development
1.60 2.40e-03 GO:0030154 cell differentiation
1.56 8.07e-03 GO:0048869 cellular developmental process
1.54 1.04e-03 GO:0071842 cellular component organization at cellular level
1.48 2.66e-05 GO:0032502 developmental process
1.48 6.61e-03 GO:0071841 cellular component organization or biogenesis at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
29.32 1.22e-02 GO:0005588 collagen type V
24.43 8.29e-05 GO:0005587 collagen type IV
20.94 2.82e-04 GO:0030935 sheet-forming collagen
15.99 1.93e-04 GO:0005583 fibrillar collagen
13.85 1.42e-13 GO:0005581 collagen
6.23 1.66e-10 GO:0044420 extracellular matrix part
5.87 2.66e-05 GO:0005604 basement membrane
4.89 2.81e-04 GO:0030027 lamellipodium
3.55 8.00e-09 GO:0005578 proteinaceous extracellular matrix
3.25 1.89e-08 GO:0031012 extracellular matrix
3.11 3.94e-03 GO:0031252 cell leading edge
1.76 3.21e-02 GO:0042995 cell projection
1.15 4.58e-04 GO:0044424 intracellular part
1.14 1.03e-03 GO:0005622 intracellular
1.14 4.83e-02 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
29.32 1.50e-02 GO:0042799 histone methyltransferase activity (H4-K20 specific)
18.66 5.88e-06 GO:0048407 platelet-derived growth factor binding
5.87 3.91e-06 GO:0005201 extracellular matrix structural constituent
3.67 5.66e-03 GO:0035091 phosphatidylinositol binding
1.47 3.07e-02 GO:0008270 zinc ion binding
1.22 3.82e-03 GO:0005515 protein binding
1.12 8.80e-03 GO:0005488 binding