Motif ID: AGCUUAU

Z-value: 0.487


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
hsa-miR-21 MIMAT0000076
hsa-miR-590-5p MIMAT0003258



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_18480203 0.266 NM_001131010
SATB1
SATB homeobox 1
chr3_-_18466759 0.265 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr1_+_203274646 0.198 NM_006763
BTG2
BTG family, member 2
chr4_+_86699846 0.154 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr4_+_86396251 0.152 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr4_+_86851425 0.147 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr10_+_112631552 0.142 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr8_-_9009050 0.109 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr8_-_9008138 0.097 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr16_+_4382224 0.096 NM_032575
GLIS2
GLIS family zinc finger 2
chr8_+_98881277 0.093 NM_002380
NM_030583
MATN2

matrilin 2

chr9_-_95244750 0.092 NM_001193335
NM_017680
ASPN

asporin

chr10_+_72163860 0.088 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr22_+_46546498 0.085 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr3_-_24536176 0.084 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr9_-_98270830 0.076 NM_000264
PTCH1
patched 1
chr8_-_22550708 0.073 NM_004430
EGR3
early growth response 3
chr8_-_22549901 0.070 NM_001199880
EGR3
early growth response 3
chr17_-_32690180 0.068 NM_002981
CCL1
chemokine (C-C motif) ligand 1
chr2_-_55459698 0.068 NM_001135598
C2orf63
chromosome 2 open reading frame 63

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
4.02 9.30e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.53 1.60e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.52 1.69e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.46 1.13e-03 GO:0051254 positive regulation of RNA metabolic process
3.45 1.47e-02 GO:0045892 negative regulation of transcription, DNA-dependent
3.43 1.32e-03 GO:0010628 positive regulation of gene expression
3.38 1.89e-02 GO:0051253 negative regulation of RNA metabolic process
3.36 3.25e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
3.26 1.63e-02 GO:0010629 negative regulation of gene expression
3.23 5.89e-03 GO:0031327 negative regulation of cellular biosynthetic process
3.16 7.93e-03 GO:0009890 negative regulation of biosynthetic process
3.11 5.79e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
3.05 7.51e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.96 1.17e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
2.91 5.60e-03 GO:0006351 transcription, DNA-dependent
2.73 9.53e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.72 4.00e-02 GO:0009891 positive regulation of biosynthetic process
2.70 2.77e-02 GO:0031324 negative regulation of cellular metabolic process
2.67 3.25e-02 GO:0010605 negative regulation of macromolecule metabolic process
2.62 2.76e-02 GO:0032774 RNA biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.62 3.54e-02 GO:0044451 nucleoplasm part
2.21 1.36e-02 GO:0005654 nucleoplasm
1.48 8.92e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.25 5.96e-04 GO:0043565 sequence-specific DNA binding
3.04 3.75e-05 GO:0001071 nucleic acid binding transcription factor activity
3.04 3.75e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.69 1.23e-02 GO:0003676 nucleic acid binding
1.20 1.83e-02 GO:0005488 binding