Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 2.976


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNTchr1_-_150849211-0.811.5e-02Click!
AHRchr7_+_17338182-0.541.7e-01Click!
ARNT2chr15_+_806965690.442.7e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_160822625 2.662 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
 B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr15_+_41136622 2.379 NM_001032367
 SPINT1
serine peptidase inhibitor, Kunitz type 1
chr15_+_41136178 2.223 NM_003710
NM_181642
 SPINT1

serine peptidase inhibitor, Kunitz type 1

chr6_+_43738757 2.215 VEGFA
vascular endothelial growth factor A
chr10_-_103879933 2.170 NM_001113407
 LDB1
LIM domain binding 1
chr16_+_22825806 2.060 NM_006043
 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_+_219575507 1.971 NM_014640
 TTLL4
tubulin tyrosine ligase-like family, member 4
chr16_+_22825481 1.824 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr8_+_31497267 1.786 NM_013962
 NRG1
neuregulin 1
chr4_+_94750041 1.732 NM_005172
 ATOH1
atonal homolog 1 (Drosophila)
chr20_+_20348744 1.697 NM_002196
 INSM1
insulinoma-associated 1
chr2_+_219575684 1.663 TTLL4
tubulin tyrosine ligase-like family, member 4
chr3_+_57994087 1.638 NM_001164317
NM_001164318
NM_001164319
NM_001457
 FLNB



filamin B, beta



chr12_+_4382882 1.619 NM_001759
 CCND2
cyclin D2
chr1_-_205649616 1.436 NM_033102
 SLC45A3
solute carrier family 45, member 3
chr1_-_205649537 1.402 SLC45A3
solute carrier family 45, member 3
chr12_+_83080901 1.331 NM_152588
 TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr1_-_6662681 1.285 KLHL21
kelch-like 21 (Drosophila)
chr2_+_26568900 1.275 NM_033505
 EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr3_-_171177851 1.263 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
 TNIK







TRAF2 and NCK interacting kinase








Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 126 entries
enrichment   p-value GO term description
2.85 1.54e-03 GO:0031124 mRNA 3'-end processing
2.63 9.31e-04 GO:0051168 nuclear export
2.49 1.84e-02 GO:0031123 RNA 3'-end processing
2.48 2.76e-03 GO:0021537 telencephalon development
2.35 2.21e-06 GO:0030900 forebrain development
2.33 5.80e-05 GO:0045165 cell fate commitment
2.15 3.28e-02 GO:0006399 tRNA metabolic process
2.06 6.17e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
2.01 1.85e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
2.01 2.65e-02 GO:0000226 microtubule cytoskeleton organization
1.93 1.23e-06 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.92 2.06e-06 GO:0007420 brain development
1.92 2.59e-02 GO:0051169 nuclear transport
1.91 6.90e-07 GO:0006397 mRNA processing
1.90 4.32e-02 GO:0006913 nucleocytoplasmic transport
1.89 2.94e-02 GO:0032582 negative regulation of gene-specific transcription
1.84 1.05e-10 GO:0006396 RNA processing
1.83 2.42e-03 GO:0034660 ncRNA metabolic process
1.83 4.27e-02 GO:0043193 positive regulation of gene-specific transcription
1.79 1.01e-02 GO:0007017 microtubule-based process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
2.15 4.98e-02 GO:0008076 voltage-gated potassium channel complex
2.15 4.98e-02 GO:0034705 potassium channel complex
1.71 3.50e-02 GO:0016604 nuclear body
1.69 5.73e-18 GO:0005654 nucleoplasm
1.69 2.32e-02 GO:0005667 transcription factor complex
1.67 1.85e-08 GO:0044451 nucleoplasm part
1.63 6.38e-22 GO:0031981 nuclear lumen
1.60 2.96e-04 GO:0005730 nucleolus
1.57 8.76e-23 GO:0070013 intracellular organelle lumen
1.57 8.42e-22 GO:0044428 nuclear part
1.55 1.71e-22 GO:0031974 membrane-enclosed lumen
1.55 1.17e-21 GO:0043233 organelle lumen
1.28 7.39e-19 GO:0005634 nucleus
1.26 3.46e-15 GO:0044446 intracellular organelle part
1.26 2.74e-05 GO:0043228 non-membrane-bounded organelle
1.26 2.74e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.25 1.20e-14 GO:0044422 organelle part
1.25 3.11e-02 GO:0012505 endomembrane system
1.20 5.65e-20 GO:0043231 intracellular membrane-bounded organelle
1.19 9.77e-20 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
3.34 3.38e-02 GO:0003727 single-stranded RNA binding
1.99 1.98e-03 GO:0016741 transferase activity, transferring one-carbon groups
1.96 4.80e-03 GO:0008168 methyltransferase activity
1.73 1.27e-03 GO:0016563 transcription activator activity
1.64 5.02e-09 GO:0003723 RNA binding
1.61 1.35e-03 GO:0004674 protein serine/threonine kinase activity
1.54 5.23e-04 GO:0004672 protein kinase activity
1.49 3.07e-06 GO:0030528 transcription regulator activity
1.46 1.71e-15 GO:0000166 nucleotide binding
1.45 2.03e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.45 3.48e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.44 8.90e-03 GO:0043565 sequence-specific DNA binding
1.41 1.08e-02 GO:0016301 kinase activity
1.40 1.13e-06 GO:0005524 ATP binding
1.39 3.54e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.39 1.68e-06 GO:0030554 adenyl nucleotide binding
1.39 2.29e-06 GO:0032559 adenyl ribonucleotide binding
1.38 9.76e-08 GO:0017076 purine nucleotide binding
1.38 3.85e-03 GO:0001071 nucleic acid binding transcription factor activity
1.38 3.85e-03 GO:0003700 sequence-specific DNA binding transcription factor activity