Motif ID: ATF6.p2

Z-value: 1.660


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_161736033-0.695.7e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_94024201 3.504 COL1A2
collagen, type I, alpha 2
chr1_+_183605207 2.968 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr7_+_94023872 2.539 NM_000089
 COL1A2
collagen, type I, alpha 2
chr5_-_172198160 2.360 NM_004417
 DUSP1
dual specificity phosphatase 1
chr11_+_113930296 2.341 ZBTB16
zinc finger and BTB domain containing 16
chr11_+_113930430 2.325 NM_006006
 ZBTB16
zinc finger and BTB domain containing 16
chr19_+_49458151 2.174 BAX
BCL2-associated X protein
chr4_+_145567147 2.100 NM_022475
 HHIP
hedgehog interacting protein
chr19_+_49458129 2.057 BAX
BCL2-associated X protein
chr19_+_49458031 2.047 NM_004324
NM_138761
NM_138763
NM_138764
 BAX



BCL2-associated X protein



chr20_+_33292117 2.017 NM_021202
 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr11_-_35547144 1.954 NM_001001991
NM_015430
 PAMR1

peptidase domain containing associated with muscle regeneration 1

chr19_+_50031232 1.945 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr3_-_187463227 1.897 BCL6
B-cell CLL/lymphoma 6
chr3_-_187463474 1.705 NM_001706
 BCL6
B-cell CLL/lymphoma 6
chr20_+_33146500 1.701 NM_032514
 MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr2_-_145277568 1.545 ZEB2
zinc finger E-box binding homeobox 2
chr4_-_39640461 1.528 NM_174921
 C4orf34
chromosome 4 open reading frame 34
chr14_+_101292483 1.527


chr22_-_20850075 1.524 NM_032775
 KLHL22
kelch-like 22 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
10.03 1.42e-02 GO:0048194 Golgi vesicle budding
10.03 1.42e-02 GO:0048200 Golgi transport vesicle coating
10.03 1.42e-02 GO:0048205 COPI coating of Golgi vesicle
8.27 2.48e-05 GO:0048199 vesicle targeting, to, from or within Golgi
7.52 1.65e-03 GO:0006891 intra-Golgi vesicle-mediated transport
6.45 8.32e-03 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
6.27 3.23e-03 GO:0006901 vesicle coating
6.02 4.79e-04 GO:0006903 vesicle targeting
6.02 5.06e-03 GO:0006900 membrane budding
4.66 4.65e-03 GO:0051650 establishment of vesicle localization
4.05 1.20e-02 GO:0006914 autophagy
3.99 2.07e-09 GO:0048193 Golgi vesicle transport
3.97 1.53e-02 GO:0051648 vesicle localization
2.62 3.14e-02 GO:0006184 GTP catabolic process
2.37 2.53e-06 GO:0006886 intracellular protein transport
2.29 7.09e-08 GO:0070727 cellular macromolecule localization
2.28 1.39e-07 GO:0034613 cellular protein localization
2.07 1.35e-09 GO:0015031 protein transport
2.05 1.81e-09 GO:0045184 establishment of protein localization
2.03 5.16e-08 GO:0046907 intracellular transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 43 entries
enrichment   p-value GO term description
4.24 1.30e-02 GO:0030120 vesicle coat
3.85 3.49e-02 GO:0031234 extrinsic to internal side of plasma membrane
3.42 8.92e-03 GO:0030117 membrane coat
3.42 8.92e-03 GO:0048475 coated membrane
3.12 9.39e-03 GO:0000790 nuclear chromatin
2.86 1.17e-02 GO:0030133 transport vesicle
2.71 3.93e-02 GO:0005795 Golgi stack
2.62 2.73e-02 GO:0030662 coated vesicle membrane
2.60 1.13e-04 GO:0030135 coated vesicle
2.22 2.52e-07 GO:0000139 Golgi membrane
2.22 4.06e-03 GO:0000785 chromatin
2.06 5.40e-07 GO:0044431 Golgi apparatus part
2.04 1.94e-02 GO:0030659 cytoplasmic vesicle membrane
2.03 1.74e-02 GO:0012506 vesicle membrane
1.94 8.47e-03 GO:0048471 perinuclear region of cytoplasm
1.89 4.26e-02 GO:0044433 cytoplasmic vesicle part
1.82 1.48e-07 GO:0005794 Golgi apparatus
1.78 3.03e-03 GO:0005694 chromosome
1.78 1.57e-02 GO:0044427 chromosomal part
1.67 3.00e-03 GO:0016023 cytoplasmic membrane-bounded vesicle

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.59 2.01e-03 GO:0001071 nucleic acid binding transcription factor activity
1.59 2.01e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.26 1.86e-10 GO:0005515 protein binding
1.12 5.39e-07 GO:0005488 binding