Motif ID: AUGUGCC

Z-value: 0.370


Mature miRNA associated with seed AUGUGCC:

NamemiRBase Accession
hsa-miR-455-5p MIMAT0003150



Activity profile for motif AUGUGCC.

activity profile for motif AUGUGCC


Sorted Z-values histogram for motif AUGUGCC

Sorted Z-values for motif AUGUGCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGUGCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_101702304 0.223 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr8_+_75736771 0.191 NM_015886
PI15
peptidase inhibitor 15
chr10_-_105614952 0.133 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr1_-_62785067 0.123 NM_181712
KANK4
KN motif and ankyrin repeat domains 4
chr8_-_93107881 0.096 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr8_-_93111915 0.095 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93115453 0.095 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr8_-_93107442 0.093 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr8_-_93075190 0.090 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93029864 0.084 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_41937105 0.080 NM_018126
TMEM33
transmembrane protein 33
chr16_+_22825806 0.079 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr16_+_69139466 0.079 NM_001199280
HAS3
hyaluronan synthase 3
chr16_+_69141442 0.077 NM_005329
HAS3
hyaluronan synthase 3
chr7_-_141646716 0.077 NM_013252
CLEC5A
C-type lectin domain family 5, member A
chr18_-_28622624 0.072 NM_001941
NM_024423
DSC3

desmocollin 3

chr7_+_37960162 0.066 NM_001242946
NM_017549
EPDR1

ependymin related protein 1 (zebrafish)

chr5_+_68788118 0.065 NM_002538
OCLN
occludin
chr4_-_42154894 0.064 NM_001159547
NM_207406
BEND4

BEN domain containing 4

chr4_-_139163222 0.062 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr5_+_68800003 0.061 NM_001205255
OCLN
occludin
chr5_+_68788387 0.061 NM_001205254
OCLN
occludin
chr5_+_36608430 0.058 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_-_27529434 0.053 NM_024761
MOB3B
MOB kinase activator 3B
chr12_+_4382882 0.049 NM_001759
CCND2
cyclin D2
chr20_-_43438881 0.048 NM_001205317
NM_182970
RIMS4

regulating synaptic membrane exocytosis 4

chr16_+_29690328 0.046 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr11_-_57092283 0.046 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr3_-_190040192 0.045 NM_021101
CLDN1
claudin 1
chr6_+_121756744 0.043 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr15_-_30114536 0.040 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chrX_-_117250624 0.039 NM_001168302
NM_001168303
KLHL13

kelch-like 13 (Drosophila)

chrX_-_117251302 0.039 NM_001168301
KLHL13
kelch-like 13 (Drosophila)
chr17_-_42907606 0.038 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr14_+_96671015 0.038 NM_000623
BDKRB2
bradykinin receptor B2
chr21_-_16437125 0.037 NM_003489
NRIP1
nuclear receptor interacting protein 1
chr20_+_58630965 0.037 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr11_+_111411232 0.037 NM_178834
LAYN
layilin
chr2_-_176866925 0.037 NM_030650
KIAA1715
KIAA1715
chr12_-_71003622 0.036 NM_001206971
NM_001206972
NM_002837
PTPRB


protein tyrosine phosphatase, receptor type, B


chr10_+_23983674 0.036 NM_001098500
KIAA1217
KIAA1217
chr5_-_160975124 0.035 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr11_-_108464344 0.035 NM_015065
EXPH5
exophilin 5
chr11_+_43380403 0.035 NM_018259
TTC17
tetratricopeptide repeat domain 17
chr16_+_50321822 0.034 NM_001114
ADCY7
adenylate cyclase 7
chr18_+_33877630 0.034 NM_025135
FHOD3
formin homology 2 domain containing 3
chr12_-_71031174 0.032 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chrX_-_117119282 0.032 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr12_+_83080901 0.032 NM_152588
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chrX_-_117107700 0.032 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chr16_-_75528925 0.031 NM_021615
CHST6
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
chr12_+_113659216 0.031 NM_001143819
NM_017901
TPCN1

two pore segment channel 1

chr7_+_20370724 0.029 NM_002214
ITGB8
integrin, beta 8
chr5_+_126626455 0.029 NM_032446
MEGF10
multiple EGF-like-domains 10
chr4_-_170947428 0.029 NM_021647
MFAP3L
microfibrillar-associated protein 3-like
chr1_+_161676761 0.028 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr1_-_47069936 0.028 NM_001135553
NM_003684
NM_198973
MKNK1


MAP kinase interacting serine/threonine kinase 1


chr17_-_42908178 0.027 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr11_-_88070905 0.027 NM_001114173
NM_001814
NM_148170
CTSC


cathepsin C


chr10_-_90611675 0.026 NM_144590
ANKRD22
ankyrin repeat domain 22
chrX_+_68725077 0.026 NM_015686
FAM155B
family with sequence similarity 155, member B
chr6_-_119670897 0.025 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr13_-_46756326 0.025 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_-_2160199 0.025 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_-_170219012 0.025 NM_004525
LRP2
low density lipoprotein receptor-related protein 2
chr2_-_101925051 0.024 NM_173647
RNF149
ring finger protein 149
chr6_+_41196061 0.024 NM_198153
TREML4
triggering receptor expressed on myeloid cells-like 4
chr12_+_78225068 0.024 NM_014903
NAV3
neuron navigator 3
chr3_-_53164417 0.024 NM_052859
RFT1
RFT1 homolog (S. cerevisiae)
chrX_+_67718623 0.023 NM_001195214
NM_173834
YIPF6

Yip1 domain family, member 6

chr11_-_2162340 0.023 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_198570027 0.023 NM_138395
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr3_-_50340979 0.022 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr11_-_2170792 0.022 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_+_117452359 0.022 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr9_-_74979829 0.022 NM_001102420
NM_001102421
NM_006007
ZFAND5


zinc finger, AN1-type domain 5


chr3_-_50349811 0.022 NM_153281
HYAL1
hyaluronoglucosaminidase 1
chr12_-_22487566 0.021 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr2_-_38978397 0.021 NM_001031684
NM_001195446
SRSF7

serine/arginine-rich splicing factor 7

chr11_+_93862060 0.021 NM_015368
PANX1
pannexin 1
chr9_-_4300028 0.021 NM_001042413
GLIS3
GLIS family zinc finger 3
chr16_-_10674443 0.021 NM_001424
EMP2
epithelial membrane protein 2
chr8_-_15095791 0.020 NM_139167
SGCZ
sarcoglycan, zeta
chr2_+_26568900 0.020 NM_033505
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr22_+_37309618 0.020 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr10_-_30638200 0.020 NM_018109
MTPAP
mitochondrial poly(A) polymerase
chr1_-_53793743 0.020 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr1_+_158149736 0.019 NM_001766
CD1D
CD1d molecule
chr5_+_149109814 0.019 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr4_+_41983712 0.019 NM_001029955
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr1_+_95558072 0.019 NM_001199679
TMEM56
transmembrane protein 56
chr5_-_148442606 0.019 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr19_-_54876671 0.019 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr4_-_170924911 0.019 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr14_+_85996454 0.019 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr18_+_42260774 0.019 NM_015559
SETBP1
SET binding protein 1
chr10_+_82213892 0.019 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr12_+_88536045 0.019 NM_181783
TMTC3
transmembrane and tetratricopeptide repeat containing 3
chr10_+_24497719 0.018 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr1_-_10856704 0.018 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr7_-_122526781 0.018 NM_001009571
NM_001167940
NM_017954
CADPS2


Ca++-dependent secretion activator 2


chr18_-_21242592 0.018 NM_173505
ANKRD29
ankyrin repeat domain 29
chr13_-_107187312 0.018 NM_004093
EFNB2
ephrin-B2
chr15_-_75017710 0.017 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr19_-_14889347 0.017 NM_013447
NM_152916
NM_152917
NM_152918
NM_152919
NM_152920
NM_152921
EMR2






egf-like module containing, mucin-like, hormone receptor-like 2






chr2_+_106468203 0.017 NM_001004720
NCK2
NCK adaptor protein 2
chr1_+_241815579 0.017 NM_144625
WDR64
WD repeat domain 64
chr15_-_72612497 0.017 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr20_+_1875382 0.017 NM_080792
SIRPA
signal-regulatory protein alpha
chr20_+_1875825 0.017 NM_001040023
SIRPA
signal-regulatory protein alpha
chr2_-_122042767 0.017 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr15_-_72612247 0.017 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr6_-_31088195 0.017 NM_001264
CDSN
corneodesmosin
chr3_-_194188967 0.017 NM_024524
ATP13A3
ATPase type 13A3
chr14_-_39901619 0.017 NM_203301
FBXO33
F-box protein 33
chr19_+_58694381 0.017 NM_016324
NM_016325
NM_133502
ZNF274


zinc finger protein 274


chr5_+_149151502 0.016 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chrX_+_113818550 0.016 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C
chr17_-_43394326 0.016 NM_003954
MAP3K14
mitogen-activated protein kinase kinase kinase 14
chr14_+_24782312 0.016 NM_181657
LTB4R
leukotriene B4 receptor
chr11_+_60467046 0.016 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr3_-_160167600 0.016 NM_173084
TRIM59
tripartite motif containing 59
chr2_+_106361404 0.016 NM_001004722
NM_003581
NCK2

NCK adaptor protein 2

chr13_+_113344354 0.016 NM_015205
NM_032189
ATP11A

ATPase, class VI, type 11A

chr1_+_203595897 0.016 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr1_+_95582827 0.016 NM_152487
TMEM56
transmembrane protein 56
chr20_+_1874779 0.016 NM_001040022
SIRPA
signal-regulatory protein alpha
chr5_-_150284503 0.016 NM_001172831
NM_001172832
NM_052860
ZNF300


zinc finger protein 300


chr9_-_34637752 0.015 NM_005866
NM_147157
SIGMAR1

sigma non-opioid intracellular receptor 1

chr12_-_112546562 0.015 NM_024953
NAA25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr17_-_50237342 0.015 NM_001082534
CA10
carbonic anhydrase X
chr14_+_24780654 0.015 NM_001143919
LTB4R
leukotriene B4 receptor
chr13_+_80055257 0.015 NM_001161407
NM_019080
NDFIP2

Nedd4 family interacting protein 2

chr17_-_50237160 0.015 NM_001082533
CA10
carbonic anhydrase X
chr1_-_173962050 0.015 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr6_-_11044354 0.015 NM_017770
ELOVL2
ELOVL fatty acid elongase 2
chr12_+_2162388 0.014 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr21_+_37692477 0.014 NM_015358
MORC3
MORC family CW-type zinc finger 3
chr2_-_134326030 0.014 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr15_+_73344824 0.014 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr7_-_94953827 0.014 NM_000446
PON1
paraoxonase 1
chr4_-_111119752 0.014 NM_001130721
NM_024090
ELOVL6

ELOVL fatty acid elongase 6

chr14_-_53162418 0.014 NM_014584
ERO1L
ERO1-like (S. cerevisiae)
chr8_-_61193882 0.014 NM_004056
CA8
carbonic anhydrase VIII
chr1_-_23495347 0.014 NM_001142546
NM_033631
LUZP1

leucine zipper protein 1

chr9_-_95055989 0.014 NM_002161
IARS
isoleucyl-tRNA synthetase
chr11_-_19082227 0.014 NM_054030
MRGPRX2
MAS-related GPR, member X2
chr4_-_90758126 0.013 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr4_+_177241003 0.013 NM_021928
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chrX_-_73834460 0.013 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr15_-_41047448 0.013 NM_018145
FAM82A2
family with sequence similarity 82, member A2
chr8_+_25042254 0.013 NM_024940
DOCK5
dedicator of cytokinesis 5
chr9_-_21031607 0.013 NM_001010915
PTPLAD2
protein tyrosine phosphatase-like A domain containing 2
chr9_-_95055966 0.013 NM_013417
IARS
isoleucyl-tRNA synthetase
chr2_+_85198176 0.013 NM_020122
KCMF1
potassium channel modulatory factor 1
chr7_-_138665853 0.013 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr15_+_59279849 0.013 NM_017610
RNF111
ring finger protein 111
chr4_-_46996423 0.013 NM_000809
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr2_+_70142152 0.013 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr4_-_90759446 0.013 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr11_-_125648704 0.013 NM_212555
PATE2
prostate and testis expressed 2
chr8_-_42397048 0.013 NM_006749
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr4_+_152330326 0.013 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr17_-_50236124 0.012 NM_020178
CA10
carbonic anhydrase X
chr7_-_82792127 0.012 NM_014510
NM_033026
PCLO

piccolo (presynaptic cytomatrix protein)

chrX_+_40944858 0.012 NM_001039590
NM_001039591
USP9X

ubiquitin specific peptidase 9, X-linked

chr14_-_64194692 0.012 NM_030791
SGPP1
sphingosine-1-phosphate phosphatase 1
chr3_-_27498244 0.012 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr11_+_100557851 0.012 NM_152432
ARHGAP42
Rho GTPase activating protein 42
chr7_+_11013453 0.012 NM_014660
PHF14
PHD finger protein 14
chr4_+_7194317 0.012 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr9_-_4152182 0.012 NM_152629
GLIS3
GLIS family zinc finger 3
chr5_+_38403633 0.012 NM_182798
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr2_+_204103163 0.011 NM_177538
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr18_-_712503 0.011 NM_202758
NM_001126123
NM_017512
ENOSF1


enolase superfamily member 1


chr5_+_38258510 0.011 NM_001205301
NM_152403
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr6_-_108279409 0.011 NM_007214
SEC63
SEC63 homolog (S. cerevisiae)
chr4_+_141445311 0.011 NM_153702
ELMOD2
ELMO/CED-12 domain containing 2
chr9_+_101705710 0.011 NM_001855
COL15A1
collagen, type XV, alpha 1
chr18_+_13726658 0.011 NM_003799
RNMT
RNA (guanine-7-) methyltransferase
chr5_+_38445577 0.011 NM_182801
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr15_+_67458492 0.011 NM_001145104
SMAD3
SMAD family member 3
chr8_-_101322245 0.011 NM_183419
RNF19A
ring finger protein 19A
chr14_+_33408458 0.011 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr9_+_132815984 0.011 NM_001136557
NM_001136558
NM_020960
GPR107


G protein-coupled receptor 107


chr7_-_86688944 0.011 NM_001142749
KIAA1324L
KIAA1324-like
chr9_-_111882209 0.011 NM_032012
C9orf5
chromosome 9 open reading frame 5
chr6_+_76458888 0.011 NM_004999
MYO6
myosin VI
chr15_-_72598655 0.011 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr2_-_55277698 0.011 NM_020532
NM_153828
NM_207520
RTN4


reticulon 4


chr15_-_86338178 0.011 NM_022480
KLHL25
kelch-like 25 (Drosophila)
chr10_-_91295310 0.011 NM_213606
SLC16A12
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr10_-_5045967 0.011 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr12_-_51591949 0.010 NM_002702
POU6F1
POU class 6 homeobox 1
chr5_-_115910406 0.010 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr4_-_55991746 0.010 NM_002253
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr20_+_62184372 0.010 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr7_+_45614081 0.010 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr12_+_65218351 0.010 NM_015279
TBC1D30
TBC1 domain family, member 30
chr7_-_44924946 0.010 NM_033224
PURB
purine-rich element binding protein B

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.38 6.83e-06 GO:0044425 membrane part
1.72 6.24e-05 GO:0044459 plasma membrane part
1.36 5.42e-04 GO:0016021 integral to membrane
1.35 1.20e-03 GO:0031224 intrinsic to membrane
1.25 4.22e-03 GO:0016020 membrane
2.21 8.89e-03 GO:0030054 cell junction

Nothing significant found in function category.