Motif ID: BACH2.p2

Z-value: 0.251


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BACH2chr6_-_910065800.078.6e-01Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_21452981 0.977 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr1_+_153003677 0.716 NM_003125
SPRR1B
small proline-rich protein 1B
chr2_+_47596286 0.430 NM_002354
EPCAM
epithelial cell adhesion molecule
chr2_+_47596447 0.415 EPCAM
epithelial cell adhesion molecule
chr20_+_44637539 0.405 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr11_-_118134986 0.401 MPZL2
myelin protein zero-like 2
chr11_-_118134956 0.392 MPZL2
myelin protein zero-like 2
chr11_-_118135197 0.373 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr19_-_36004553 0.352 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr11_-_102668822 0.349 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr19_-_51523272 0.347 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr19_-_35992798 0.342 NM_001035516
DMKN
dermokine
chr11_-_102668892 0.341 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr1_-_209824641 0.322 NM_001017402
LAMB3
laminin, beta 3
chr1_+_183155361 0.317 LAMC2
laminin, gamma 2
chr18_+_61442611 0.311 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr17_-_39768939 0.297 NM_005557
KRT16
keratin 16
chr1_+_152956563 0.285 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr14_-_94855120 0.284 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr16_+_57662301 0.272 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr3_-_151034514 0.262 NM_023915
GPR87
G protein-coupled receptor 87
chr14_-_94854910 0.252 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_+_32043745 0.235 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_183155393 0.230 LAMC2
laminin, gamma 2
chr19_-_44174497 0.227 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr14_-_94849552 0.222 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_+_183155173 0.222 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr18_-_47376156 0.218 MYO5B
myosin VB
chr11_+_10476665 0.215 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr10_-_129691202 0.213 NM_152311
CLRN3
clarin 3
chr10_-_88730928 0.211 LOC100133190
uncharacterized LOC100133190
chr10_+_118187381 0.207 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr11_+_12308446 0.196 NM_032867
MICALCL
MICAL C-terminal like
chr19_+_7953380 0.193 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr19_-_43969723 0.190 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr8_+_120220554 0.177 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr12_-_53343607 0.170 KRT8
keratin 8
chr19_-_44174271 0.167 PLAUR
plasminogen activator, urokinase receptor
chr3_-_12800739 0.166 NM_018306
TMEM40
transmembrane protein 40
chr17_-_39538635 0.162 NM_021013
KRT34
keratin 34
chr4_-_89080010 0.162 NM_004827
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr7_+_73245192 0.158 NM_001305
CLDN4
claudin 4
chr2_+_220492286 0.156 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr6_+_30852756 0.156 NM_001202523
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_+_47666288 0.140 NM_153838
GPR115
G protein-coupled receptor 115
chr1_-_6662898 0.139 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr1_+_35246789 0.138 NM_024009
GJB3
gap junction protein, beta 3, 31kDa
chr12_+_107974633 0.138 NM_001017523
BTBD11
BTB (POZ) domain containing 11
chr12_+_56473808 0.137 NM_001982
NM_001005915
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr17_+_73717515 0.137 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr19_-_51472816 0.137 NM_002774
KLK6
kallikrein-related peptidase 6
chr18_+_55888838 0.123 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_+_145317297 0.123 SH3RF2
SH3 domain containing ring finger 2
chr12_+_56732658 0.122 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr5_+_35856990 0.121 NM_002185
IL7R
interleukin 7 receptor
chr18_+_55888799 0.117 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_-_28520379 0.111 NM_001164721
NM_001164722
PTAFR

platelet-activating factor receptor

chr5_+_147582338 0.111 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr6_+_44195008 0.111 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr11_+_394199 0.110 NM_007183
PKP3
plakophilin 3
chr2_+_113875469 0.106 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr14_-_24777160 0.105 CIDEB
cell death-inducing DFFA-like effector b
chr1_-_6662681 0.104 KLHL21
kelch-like 21 (Drosophila)
chr17_-_27467395 0.103 MYO18A
myosin XVIIIA
chr14_-_24777184 0.101 CIDEB
cell death-inducing DFFA-like effector b
chr6_-_149806025 0.100 ZC3H12D
zinc finger CCCH-type containing 12D
chr14_-_24777153 0.100 CIDEB
cell death-inducing DFFA-like effector b
chr8_-_38008332 0.099 NM_000349
STAR
steroidogenic acute regulatory protein
chr8_-_125579395 0.097 MTSS1
metastasis suppressor 1
chr1_-_40157067 0.096 NM_016257
HPCAL4
hippocalcin like 4
chr18_+_61254533 0.094 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_153521717 0.094 NM_002960
S100A3
S100 calcium binding protein A3
chr2_-_238499317 0.093 RAB17
RAB17, member RAS oncogene family
chrX_-_154563735 0.093 NM_001289
CLIC2
chloride intracellular channel 2
chr10_-_6019454 0.092 NM_002189
NM_172200
IL15RA

interleukin 15 receptor, alpha

chr4_+_84457256 0.089 AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr19_-_44285012 0.089 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr14_-_21572374 0.089


chr3_-_98241357 0.088 CLDND1
claudin domain containing 1
chr2_+_207630310 0.087 FASTKD2
FAST kinase domains 2
chr6_+_32121228 0.086 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr9_-_124990949 0.086 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr22_+_45072936 0.086 PRR5
proline rich 5 (renal)
chr2_-_31352489 0.085 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_-_44285407 0.085 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_+_15256295 0.085 NM_001018001
KAZN
kazrin, periplakin interacting protein
chr6_-_138428477 0.085 NM_022121
PERP
PERP, TP53 apoptosis effector
chr6_+_1611544 0.084 FOXC1
forkhead box C1
chr19_-_36019194 0.084 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr9_-_86983412 0.081 NM_022127
SLC28A3
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
chr15_+_90728118 0.081 NM_020210
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr4_+_159131400 0.081 NM_018342
TMEM144
transmembrane protein 144
chr16_-_30124829 0.080 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr7_+_48128225 0.079 NM_181597
UPP1
uridine phosphorylase 1
chr1_-_223853359 0.079 CAPN8
calpain 8
chr12_-_106533810 0.079 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr17_-_43502992 0.078 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr4_+_76481257 0.078 NM_001206981
NM_178497
C4orf26

chromosome 4 open reading frame 26

chr1_+_55007927 0.076 ACOT11
acyl-CoA thioesterase 11
chr4_+_84457390 0.076 NM_032717
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr22_-_30942668 0.075 NM_001193336
SEC14L6
SEC14-like 6 (S. cerevisiae)
chr1_+_3388170 0.075 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr1_+_15480213 0.072 NM_001136218
NM_018022
TMEM51

transmembrane protein 51

chr6_+_30856462 0.072 NM_001202521
NM_001202522
NM_013994
DDR1


discoidin domain receptor tyrosine kinase 1


chr17_-_38911524 0.071 NM_181534
KRT25
keratin 25
chr22_+_22758538 0.070


chr16_-_2908105 0.068 NM_022119
PRSS22
protease, serine, 22
chr17_-_10741398 0.068 NM_001101387
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr7_+_116312412 0.067 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr8_+_24771268 0.067 NM_005382
NEFM
neurofilament, medium polypeptide
chr10_-_6019880 0.067 NM_001243539
IL15RA
interleukin 15 receptor, alpha
chr19_+_39279849 0.066 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr6_-_30684851 0.065 MDC1
mediator of DNA-damage checkpoint 1
chr19_-_55881740 0.065 NM_000641
IL11
interleukin 11
chr12_-_8219001 0.065 C3AR1
complement component 3a receptor 1
chr18_-_74207145 0.064 NM_014643
ZNF516
zinc finger protein 516
chr10_-_71906409 0.063 TYSND1
trypsin domain containing 1
chr11_+_62649160 0.063 SLC3A2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr16_+_30968614 0.063 NM_014712
SETD1A
SET domain containing 1A
chr15_+_40532034 0.063 NM_020168
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr6_-_30685457 0.062 NM_014641
MDC1
mediator of DNA-damage checkpoint 1
chr17_-_39216343 0.062 NM_001165252
LOC730755
keratin associated protein 2-4-like
chrX_+_30233674 0.062 NM_002364
MAGEB2
melanoma antigen family B, 2
chr19_-_39264144 0.062 NM_002307
LGALS7
LGALS7B
lectin, galactoside-binding, soluble, 7
lectin, galactoside-binding, soluble, 7B
chrX_-_74743299 0.061 NM_001146256
NM_001146257
NM_144969
ZDHHC15


zinc finger, DHHC-type containing 15


chr18_+_61144143 0.061 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_-_8218930 0.060 NM_004054
C3AR1
complement component 3a receptor 1
chr17_+_79651035 0.060 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr12_+_56473944 0.060 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr17_+_79650961 0.060 NM_004712
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chrX_+_133371076 0.059 NM_001101357
CCDC160
coiled-coil domain containing 160
chrX_-_74743085 0.059 ZDHHC15
zinc finger, DHHC-type containing 15
chr6_+_106959729 0.059 NM_001624
AIM1
absent in melanoma 1
chr12_-_51402988 0.059 SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chrX_-_74742871 0.058 ZDHHC15
zinc finger, DHHC-type containing 15
chr3_-_48601200 0.058 NM_033199
UCN2
urocortin 2
chr7_+_100663360 0.058 NM_001040105
MUC17
mucin 17, cell surface associated
chr14_-_75643286 0.058 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr7_+_37960920 0.056 NM_001242948
EPDR1
ependymin related protein 1 (zebrafish)
chr6_+_106546736 0.056 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr19_-_49658645 0.055 NM_002152
HRC
histidine rich calcium binding protein
chr11_-_65667809 0.055 FOSL1
FOS-like antigen 1
chr14_-_75643309 0.055 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr15_+_89182038 0.055 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr11_-_65667858 0.055 FOSL1
FOS-like antigen 1
chr16_+_22308722 0.054 NM_018119
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr10_+_104155431 0.054 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr3_-_122512526 0.054 NM_024610
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr11_+_1855673 0.054 NM_138567
SYT8
synaptotagmin VIII
chr10_+_24755459 0.053 KIAA1217
KIAA1217
chr7_+_37960418 0.053 EPDR1
ependymin related protein 1 (zebrafish)
chr21_-_36421630 0.052 RUNX1
runt-related transcription factor 1
chr5_-_37371198 0.052 NUP155
nucleoporin 155kDa
chr2_+_48541767 0.051 NM_002158
FOXN2
forkhead box N2
chr17_-_7493389 0.051 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr12_-_51403028 0.051 NM_001174130
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr19_-_291335 0.050 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr7_-_158611301 0.050 ESYT2
extended synaptotagmin-like protein 2
chr7_-_33080517 0.050 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr17_+_79651072 0.050 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr19_+_44116252 0.050 NM_001145641
SRRM5
serine/arginine repetitive matrix 5
chr21_-_36421578 0.050 RUNX1
runt-related transcription factor 1
chr1_+_36621751 0.049 NM_018067
MAP7D1
MAP7 domain containing 1
chr20_-_1309809 0.049 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr19_+_38794800 0.049 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr1_-_95007139 0.049 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr1_+_19638739 0.049 NM_001040125
NM_001040126
NM_017765
PQLC2


PQ loop repeat containing 2


chr14_-_75643333 0.048 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr5_+_147648374 0.047 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr5_+_140261792 0.047 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr22_+_22712091 0.047 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr12_-_323255 0.047 NM_001122848
NM_001206931
SLC6A12

solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12

chr4_+_159131642 0.047 TMEM144
transmembrane protein 144
chr14_+_68168602 0.046 NM_152443
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr5_+_145316120 0.046 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr11_+_394238 0.046 PKP3
plakophilin 3
chr22_+_22676814 0.046


chr16_-_18798077 0.046


chr20_+_43030005 0.046 HNF4A
hepatocyte nuclear factor 4, alpha
chr17_+_79651042 0.045 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr12_+_28343390 0.045


chr1_-_225616556 0.045 NM_194442
LBR
lamin B receptor
chr21_-_36421461 0.045 RUNX1
runt-related transcription factor 1
chr21_+_42733916 0.044 NM_002463
LOC100131190
MX2
uncharacterized LOC100131190
myxovirus (influenza virus) resistance 2 (mouse)
chr5_+_70944968 0.044 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr4_+_74606222 0.044 NM_000584
IL8
interleukin 8
chr1_+_901876 0.043 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr11_-_128894008 0.043 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr10_-_95170 0.043 NM_177987
TUBB8
tubulin, beta 8 class VIII
chr1_+_45769551 0.043 LOC400752
uncharacterized LOC400752
chr1_+_36621457 0.043 MAP7D1
MAP7 domain containing 1
chr17_+_74381419 0.043 SPHK1
sphingosine kinase 1
chrX_-_16730339 0.043 NM_001144002
CTPS2
CTP synthase II
chr6_-_31745048 0.042 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr3_-_98241683 0.042 CLDND1
claudin domain containing 1
chr8_+_24771276 0.042 NEFM
neurofilament, medium polypeptide
chr17_-_39743085 0.042 NM_000526
KRT14
keratin 14
chr7_-_36429695 0.042 NM_001100425
KIAA0895
KIAA0895
chr1_-_157108132 0.041 ETV3
ets variant 3
chr12_-_31479038 0.041 FAM60A
family with sequence similarity 60, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
7.59 1.12e-02 GO:0007044 cell-substrate junction assembly

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
4.64 6.03e-03 GO:0000502 proteasome complex
7.59 2.73e-02 GO:0001533 cornified envelope

Nothing significant found in function category.