Motif ID: CACAGUG

Z-value: 0.478


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128 MIMAT0000424



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_21463019 0.651 NM_001173484
NM_213569
NEBL

nebulette

chr15_+_33010174 0.595 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr6_-_88875766 0.562 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr10_-_21186530 0.496 NM_006393
NEBL
nebulette
chr2_+_30454396 0.432 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr1_-_92371558 0.429 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr5_-_111312522 0.422 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr1_-_92351613 0.412 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr5_-_111093030 0.411 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr5_-_111093792 0.410 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr5_-_111093251 0.406 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr5_-_111092918 0.402 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr1_-_57045235 0.401 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr5_-_179780314 0.395 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr1_+_221052735 0.355 NM_021958
HLX
H2.0-like homeobox
chr14_-_92414004 0.344 NM_006329
FBLN5
fibulin 5
chr6_+_136172802 0.312 NM_018945
PDE7B
phosphodiesterase 7B
chr6_-_46293628 0.301 NM_005822
RCAN2
regulator of calcineurin 2
chr14_-_89883306 0.286 NM_005197
FOXN3
forkhead box N3
chr5_+_172068188 0.275 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 78 entries
enrichment   p-value GO term description
3.74 1.09e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
3.30 1.06e-04 GO:0060284 regulation of cell development
3.25 1.80e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.22 2.37e-02 GO:0043193 positive regulation of gene-specific transcription
3.08 9.26e-03 GO:0045596 negative regulation of cell differentiation
2.97 4.31e-02 GO:0050767 regulation of neurogenesis
2.96 2.20e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.89 1.54e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.75 3.76e-06 GO:0045893 positive regulation of transcription, DNA-dependent
2.73 1.62e-02 GO:0007389 pattern specification process
2.72 1.52e-06 GO:0010628 positive regulation of gene expression
2.71 1.48e-03 GO:0032583 regulation of gene-specific transcription
2.70 1.87e-06 GO:0045595 regulation of cell differentiation
2.68 2.73e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.67 8.90e-04 GO:0072358 cardiovascular system development
2.67 8.90e-04 GO:0072359 circulatory system development
2.62 1.03e-05 GO:0051254 positive regulation of RNA metabolic process
2.60 7.91e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
2.54 8.26e-04 GO:0051253 negative regulation of RNA metabolic process
2.53 2.62e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
26.95 2.13e-02 GO:0042583 chromaffin granule
26.95 2.13e-02 GO:0042584 chromaffin granule membrane
3.06 1.99e-02 GO:0030425 dendrite
2.82 1.01e-04 GO:0043005 neuron projection
2.69 4.10e-04 GO:0045202 synapse
2.50 4.61e-02 GO:0044456 synapse part
1.27 3.03e-02 GO:0005634 nucleus
1.15 2.15e-03 GO:0005622 intracellular
1.14 1.19e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
3.02 6.48e-04 GO:0008134 transcription factor binding
2.92 7.24e-04 GO:0016563 transcription activator activity
2.64 3.94e-04 GO:0019904 protein domain specific binding
2.46 1.36e-02 GO:0000988 protein binding transcription factor activity
2.46 1.36e-02 GO:0000989 transcription factor binding transcription factor activity
2.37 3.51e-02 GO:0003712 transcription cofactor activity
2.19 6.47e-06 GO:0030528 transcription regulator activity
2.17 1.68e-05 GO:0001071 nucleic acid binding transcription factor activity
2.17 1.68e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.07 1.01e-02 GO:0043565 sequence-specific DNA binding
1.26 1.13e-03 GO:0005515 protein binding