Motif ID: CCAGUGU

Z-value: 0.714


Mature miRNA associated with seed CCAGUGU:

NamemiRBase Accession
hsa-miR-199a-5p MIMAT0000231
hsa-miR-199b-5p MIMAT0000263



Activity profile for motif CCAGUGU.

activity profile for motif CCAGUGU


Sorted Z-values histogram for motif CCAGUGU

Sorted Z-values for motif CCAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CCAGUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_12990731 0.580 NM_006094
DLC1
deleted in liver cancer 1
chr8_+_37654395 0.556 NM_032777
GPR124
G protein-coupled receptor 124
chr8_-_12973752 0.536 NM_001164271
DLC1
deleted in liver cancer 1
chr6_+_72926462 0.446 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_72922513 0.444 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr6_+_72926144 0.423 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_73076431 0.400 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr7_+_100770378 0.397 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr1_-_208417635 0.369 NM_025179
PLXNA2
plexin A2
chr2_-_19558371 0.358 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr8_-_93115453 0.354 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr4_+_55523906 0.346 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr3_-_129325175 0.338 NM_015103
PLXND1
plexin D1
chr2_+_241938254 0.317 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr15_-_48470453 0.316 NM_016132
MYEF2
myelin expression factor 2
chr8_-_93029864 0.310 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_101767714 0.305 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr8_-_93107442 0.305 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr8_-_93107881 0.304 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr8_-_93111915 0.303 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_15165873 0.298 NM_153321
PMP22
peripheral myelin protein 22
chr17_-_15168590 0.288 NM_000304
PMP22
peripheral myelin protein 22
chr17_-_15164043 0.288 NM_153322
PMP22
peripheral myelin protein 22
chr19_-_11308184 0.284 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr7_-_50861114 0.277 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr7_-_50800018 0.269 NM_001001549
NM_005311
GRB10

growth factor receptor-bound protein 10

chr19_-_10121041 0.253 NM_015719
COL5A3
collagen, type V, alpha 3
chr9_-_107690526 0.252 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr16_+_55515468 0.246 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr7_-_131241321 0.243 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr1_-_145826928 0.242 NM_001097612
NM_001097613
GPR89B
GPR89A

G protein-coupled receptor 89B
G protein-coupled receptor 89A

chr13_-_24007822 0.239 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr16_+_55512801 0.234 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr16_-_17564737 0.234 NM_022166
XYLT1
xylosyltransferase I
chr19_-_11305186 0.233 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr22_-_34316325 0.231 NM_004737
NM_133642
LARGE

like-glycosyltransferase

chr8_-_93075190 0.229 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_-_50772997 0.228 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr4_-_99579540 0.228 NM_005723
TSPAN5
tetraspanin 5
chr8_+_42128797 0.214 NM_001190720
NM_001242778
NM_001556
IKBKB


inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta


chr5_-_58334936 0.210 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr6_+_72596648 0.209 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_109335906 0.208 NM_006267
RANBP2
RAN binding protein 2
chr16_+_16043206 0.204 NM_004996
NM_019862
NM_019898
NM_019899
NM_019900
ABCC1




ATP-binding cassette, sub-family C (CFTR/MRP), member 1




chr15_-_52821004 0.197 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr7_+_856251 0.196 NM_001171944
NM_001171945
NM_025154
SUN1


Sad1 and UNC84 domain containing 1


chr20_-_62601140 0.191 NM_020713
ZNF512B
zinc finger protein 512B
chr9_-_111882209 0.191 NM_032012
C9orf5
chromosome 9 open reading frame 5
chr7_-_139477437 0.191 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr19_+_58258160 0.189 NM_173632
ZNF776
zinc finger protein 776
chr20_+_48429249 0.188 NM_015266
SLC9A8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr1_+_179923870 0.188 NM_014810
CEP350
centrosomal protein 350kDa
chr22_+_31031672 0.182 NM_001001479
SLC35E4
solute carrier family 35, member E4
chr1_-_21616648 0.179 NM_001113349
ECE1
endothelin converting enzyme 1
chr6_-_38607923 0.177 NM_001099272
NM_052893
BTBD9

BTB (POZ) domain containing 9

chr8_-_19540093 0.176 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_+_147400498 0.174 NM_016334
GPR89B
GPR89A
G protein-coupled receptor 89B
G protein-coupled receptor 89A
chr12_+_13043955 0.171 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr22_-_28197469 0.171 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr1_+_185703470 0.167 NM_031935
HMCN1
hemicentin 1
chr1_-_21616888 0.164 NM_001397
ECE1
endothelin converting enzyme 1
chr22_-_21213099 0.159 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr10_-_25012543 0.158 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr1_-_21605984 0.155 NM_001113347
ECE1
endothelin converting enzyme 1
chr19_+_50979656 0.154 NM_175063
NM_206538
C19orf63

chromosome 19 open reading frame 63

chr15_-_93632161 0.152 NM_020211
RGMA
RGM domain family, member A
chr18_-_25757351 0.150 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr19_+_34745452 0.149 NM_014686
KIAA0355
KIAA0355
chr8_-_19460005 0.149 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_121824287 0.147 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr15_-_93631751 0.147 NM_001166287
RGMA
RGM domain family, member A
chr5_-_58295758 0.146 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_93617091 0.144 NM_001166283
RGMA
RGM domain family, member A
chr3_+_63850181 0.138 NM_000333
ATXN7
ataxin 7
chr15_-_93616358 0.136 NM_001166286
RGMA
RGM domain family, member A
chr15_-_93616891 0.136 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr12_-_122907083 0.133 NM_001247997
NM_002956
NM_198240
CLIP1


CAP-GLY domain containing linker protein 1


chr7_-_116963328 0.133 NM_003391
WNT2
wingless-type MMTV integration site family member 2
chr7_+_94536926 0.130 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr12_+_75874512 0.130 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr10_+_99496847 0.129 NM_001002262
NM_001174119
NM_001174120
NM_001174121
NM_001174122
NM_144588
ZFYVE27





zinc finger, FYVE domain containing 27





chr3_+_141043054 0.128 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr2_+_70485204 0.127 NM_016297
PCYOX1
prenylcysteine oxidase 1
chr1_-_21671905 0.127 NM_001113348
ECE1
endothelin converting enzyme 1
chr6_-_137113624 0.127 NM_005923
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr5_-_59783885 0.120 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_13372183 0.119 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr6_+_10555948 0.117 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_+_137774632 0.116 NM_016606
REEP2
receptor accessory protein 2
chr5_-_59189620 0.115 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_218518675 0.115 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr16_+_284798 0.115 NM_032039
ITFG3
integrin alpha FG-GAP repeat containing 3
chr6_-_38563763 0.114 NM_001172418
NM_152733
BTBD9

BTB (POZ) domain containing 9

chr20_-_24973410 0.114 NM_020531
C20orf3
chromosome 20 open reading frame 3
chr9_-_14693459 0.113 NM_178566
ZDHHC21
zinc finger, DHHC-type containing 21
chrX_-_99891690 0.111 NM_003270
TSPAN6
tetraspanin 6
chr10_+_99498233 0.111 NM_001002261
ZFYVE27
zinc finger, FYVE domain containing 27
chr5_-_179233772 0.110 NM_014275
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr22_-_21088954 0.109 NM_002650
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr7_-_86688944 0.109 NM_001142749
KIAA1324L
KIAA1324-like
chr1_+_90098643 0.108 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr2_-_219432955 0.108 NM_020935
USP37
ubiquitin specific peptidase 37
chrX_-_103087106 0.107 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr2_+_101436491 0.106 NM_002518
NPAS2
neuronal PAS domain protein 2
chr3_-_156878481 0.105 NM_020307
CCNL1
cyclin L1
chr4_-_138453628 0.105 NM_019035
PCDH18
protocadherin 18
chr1_+_160313061 0.104 NM_015331
NCSTN
nicastrin
chr6_+_10521564 0.102 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr16_+_87636492 0.101 NM_020655
JPH3
junctophilin 3
chr13_+_102104941 0.101 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr5_-_59064437 0.100 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_43424834 0.098 NM_006516
SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr6_+_10585978 0.098 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_+_191273012 0.097 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr11_-_66115016 0.095 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr1_+_182992329 0.094 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr10_+_31608097 0.090 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr11_+_86748870 0.090 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr14_-_36278335 0.089 NM_014990
NM_194301
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr2_+_210288668 0.088 NM_001039538
MAP2
microtubule-associated protein 2
chr5_-_58652671 0.087 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_52719514 0.087 NM_018313
PBRM1
polybromo 1
chr11_+_77300679 0.086 NM_173039
AQP11
aquaporin 11
chr15_+_84322809 0.085 NM_207517
ADAMTSL3
ADAMTS-like 3
chr10_+_31610063 0.085 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr7_-_27196163 0.084 NM_006896
HOXA7
homeobox A7
chr7_+_7222142 0.084 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr7_+_872137 0.083 NM_001130965
SUN1
Sad1 and UNC84 domain containing 1
chr16_-_52580805 0.083 NM_001080430
TOX3
TOX high mobility group box family member 3
chr3_-_172428773 0.083 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr14_+_62162042 0.081 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chrX_-_77150907 0.080 NM_032121
MAGT1
magnesium transporter 1
chr18_-_54305839 0.080 NM_004786
TXNL1
thioredoxin-like 1
chr2_+_210444364 0.080 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr10_-_101945686 0.079 NM_006459
ERLIN1
ER lipid raft associated 1
chr17_+_43224683 0.079 NM_006460
HEXIM1
hexamethylene bis-acetamide inducible 1
chr20_-_10654429 0.078 NM_000214
JAG1
jagged 1
chr7_+_116166346 0.078 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr2_-_242255114 0.078 NM_005336
HDLBP
high density lipoprotein binding protein
chr17_+_57697036 0.077 NM_004859
CLTC
clathrin, heavy chain (Hc)
chr1_-_214724974 0.077 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr12_+_119419299 0.076 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr8_+_36641841 0.075 NM_001031836
KCNU1
potassium channel, subfamily U, member 1
chr12_-_4754275 0.074 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr17_-_62050200 0.073 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr17_+_48133331 0.073 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr16_+_31483066 0.072 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chrX_+_117480027 0.071 NM_001184965
NM_001184966
NM_019045
WDR44


WD repeat domain 44


chr17_-_6544246 0.071 NM_014804
KIAA0753
KIAA0753
chr5_-_58571916 0.070 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_-_135863502 0.070 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr17_+_53342320 0.070 NM_002126
HLF
hepatic leukemia factor
chr20_-_25566137 0.070 NM_025176
NINL
ninein-like
chr1_-_231473478 0.070 NM_175876
EXOC8
exocyst complex component 8
chr5_+_98104998 0.070 NM_001012761
RGMB
RGM domain family, member B
chr19_-_16683188 0.069 NM_024881
SLC35E1
solute carrier family 35, member E1
chr2_-_47143250 0.068 NM_001171507
NM_001171510
MCFD2

multiple coagulation factor deficiency 2

chr16_+_31484497 0.068 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr20_+_34700257 0.067 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_+_34742656 0.067 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr12_-_53893195 0.067 NM_001193511
NM_006301
MAP3K12

mitogen-activated protein kinase kinase kinase 12

chr19_-_58662144 0.067 NM_024620
ZNF329
zinc finger protein 329
chr10_-_98346793 0.066 NM_020123
TM9SF3
transmembrane 9 superfamily member 3
chr16_-_52581713 0.066 NM_001146188
TOX3
TOX high mobility group box family member 3
chr4_-_53522756 0.066 NM_001134223
USP46
ubiquitin specific peptidase 46
chr3_-_48594209 0.066 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr1_-_94703252 0.065 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr12_-_56652118 0.065 NM_173595
ANKRD52
ankyrin repeat domain 52
chr22_+_41957011 0.065 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr6_-_132272311 0.064 NM_001901
CTGF
connective tissue growth factor
chr1_+_172502291 0.063 NM_016227
C1orf9
chromosome 1 open reading frame 9
chr6_+_52935770 0.063 NM_012347
FBXO9
F-box protein 9
chr3_-_52713728 0.063 NM_018165
NM_181042
PBRM1

polybromo 1

chr15_-_77363519 0.063 NM_001168412
NM_005724
NM_198902
TSPAN3


tetraspanin 3


chr12_+_46123495 0.061 NM_152641
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chrX_-_128977291 0.061 NM_001008222
ZDHHC9
zinc finger, DHHC-type containing 9
chr20_-_4982133 0.061 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr2_-_47142950 0.060 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr10_-_101945787 0.060 NM_001100626
ERLIN1
ER lipid raft associated 1
chr7_+_94539209 0.059 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr2_-_153573858 0.058 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr6_+_52930222 0.058 NM_033480
FBXO9
F-box protein 9
chr6_+_96463844 0.058 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr19_+_49660997 0.057 NM_001195227
NM_017636
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr17_+_27717942 0.057 NM_020791
NM_025142
TAOK1

TAO kinase 1

chr1_+_172502012 0.057 NM_014283
C1orf9
chromosome 1 open reading frame 9
chr8_+_104311058 0.057 NM_001164616
NM_003506
FZD6

frizzled family receptor 6

chr2_+_202316391 0.057 NM_001206864
NM_018571
STRADB

STE20-related kinase adaptor beta

chr1_+_89149836 0.056 NM_006256
PKN2
protein kinase N2
chr9_-_116163578 0.056 NM_000031
ALAD
aminolevulinate dehydratase
chr6_+_52929795 0.056 NM_033481
FBXO9
F-box protein 9
chr11_+_12399024 0.055 NM_018222
PARVA
parvin, alpha
chrX_-_128977719 0.055 NM_016032
ZDHHC9
zinc finger, DHHC-type containing 9
chr8_-_71316006 0.055 NM_006540
NCOA2
nuclear receptor coactivator 2
chr2_+_152266384 0.054 NM_001177663
NM_018151
NM_001177664
RIF1


RAP1 interacting factor homolog (yeast)


chr5_+_149887673 0.054 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_+_4387982 0.053 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr11_-_86666211 0.053 NM_012193
FZD4
frizzled family receptor 4
chrX_-_77395108 0.053 NM_015975
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr20_+_48599511 0.053 NM_005985
SNAI1
snail homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 3.24e-03 GO:0065007 biological regulation
1.30 4.82e-03 GO:0050794 regulation of cellular process
1.28 8.78e-03 GO:0050789 regulation of biological process
1.84 1.14e-02 GO:0009966 regulation of signal transduction
3.26 1.68e-02 GO:0009100 glycoprotein metabolic process
1.72 4.08e-02 GO:0023051 regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.98 4.25e-03 GO:0005794 Golgi apparatus
1.08 1.40e-02 GO:0044464 cell part
1.08 1.42e-02 GO:0005623 cell
1.67 1.95e-02 GO:0012505 endomembrane system
1.23 2.08e-02 GO:0016020 membrane
2.15 3.39e-02 GO:0044431 Golgi apparatus part

Nothing significant found in function category.