Motif ID: CREB1.p2

Z-value: 2.022


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_208394823-0.324.4e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_89618928 1.001 NM_153757
 NAP1L5
nucleosome assembly protein 1-like 5
chr19_+_54058493 0.983 NM_001079907
 ZNF331
zinc finger protein 331
chr5_-_172198160 0.947 NM_004417
 DUSP1
dual specificity phosphatase 1
chr1_+_36690038 0.919 THRAP3
thyroid hormone receptor associated protein 3
chr4_+_145567147 0.882 NM_022475
 HHIP
hedgehog interacting protein
chr10_-_93392857 0.876 NM_005398
 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr20_+_33292117 0.870 NM_021202
 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr18_+_2571509 0.840 NM_006101
 NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chr18_+_2571587 0.831 NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chrX_+_30671456 0.825 NM_000167
NM_001128127
NM_001205019
NM_203391
 GK



glycerol kinase



chr3_+_10028579 0.765 LOC442075
uncharacterized LOC442075
chr4_-_113558021 0.746 C4orf21
chromosome 4 open reading frame 21
chr18_+_76829410 0.731 ATP9B
ATPase, class II, type 9B
chr16_+_2802634 0.711 SRRM2
serine/arginine repetitive matrix 2
chr4_-_113558120 0.706 NM_018392
 C4orf21
chromosome 4 open reading frame 21
chr6_-_38607923 0.635 NM_001099272
NM_052893
 BTBD9

BTB (POZ) domain containing 9

chr11_-_28129646 0.612 KIF18A
kinesin family member 18A
chr6_-_38607635 0.607 BTBD9
BTB (POZ) domain containing 9
chr1_+_162760491 0.600 NM_016371
 HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr19_+_1248548 0.590 NM_177401
 MIDN
midnolin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
3.37 3.71e-05 GO:0051028 mRNA transport
3.32 9.06e-06 GO:0006403 RNA localization
3.32 1.67e-05 GO:0050657 nucleic acid transport
3.32 1.67e-05 GO:0050658 RNA transport
3.32 1.67e-05 GO:0051236 establishment of RNA localization
3.05 4.21e-05 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.66 6.29e-05 GO:0000375 RNA splicing, via transesterification reactions
2.66 9.68e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.66 9.68e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
2.40 1.50e-05 GO:0000087 M phase of mitotic cell cycle
2.37 4.47e-05 GO:0000280 nuclear division
2.37 4.47e-05 GO:0007067 mitosis
2.33 5.95e-05 GO:0008380 RNA splicing
2.30 1.28e-04 GO:0048285 organelle fission
2.26 5.10e-06 GO:0006397 mRNA processing
2.16 2.90e-09 GO:0006396 RNA processing
2.16 9.02e-06 GO:0000279 M phase
2.10 1.23e-06 GO:0016071 mRNA metabolic process
2.08 5.67e-07 GO:0000278 mitotic cell cycle
2.02 4.75e-03 GO:0051301 cell division

Gene overrepresentation in compartment category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
3.07 6.56e-03 GO:0071013 catalytic step 2 spliceosome
2.59 9.67e-03 GO:0016607 nuclear speck
2.52 7.04e-03 GO:0005681 spliceosomal complex
2.38 1.95e-02 GO:0000775 chromosome, centromeric region
2.22 2.35e-03 GO:0016604 nuclear body
2.06 1.15e-06 GO:0005730 nucleolus
1.96 2.75e-16 GO:0005654 nucleoplasm
1.96 5.47e-06 GO:0005694 chromosome
1.92 7.25e-03 GO:0005815 microtubule organizing center
1.90 3.06e-21 GO:0031981 nuclear lumen
1.87 4.14e-24 GO:0044428 nuclear part
1.87 6.63e-04 GO:0044427 chromosomal part
1.77 2.81e-03 GO:0030529 ribonucleoprotein complex
1.76 2.00e-19 GO:0070013 intracellular organelle lumen
1.74 8.75e-19 GO:0043233 organelle lumen
1.73 1.09e-18 GO:0031974 membrane-enclosed lumen
1.72 5.09e-04 GO:0015630 microtubule cytoskeleton
1.71 2.81e-04 GO:0044451 nucleoplasm part
1.48 8.11e-07 GO:0005829 cytosol
1.46 5.12e-25 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
3.76 1.73e-07 GO:0008026 ATP-dependent helicase activity
3.76 1.73e-07 GO:0070035 purine NTP-dependent helicase activity
3.37 1.50e-02 GO:0004221 ubiquitin thiolesterase activity
3.25 6.90e-07 GO:0004386 helicase activity
2.26 1.43e-04 GO:0042623 ATPase activity, coupled
2.21 1.43e-05 GO:0016887 ATPase activity
1.85 1.37e-06 GO:0017111 nucleoside-triphosphatase activity
1.83 1.12e-06 GO:0016462 pyrophosphatase activity
1.83 1.39e-06 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.82 1.73e-06 GO:0016817 hydrolase activity, acting on acid anhydrides
1.68 1.83e-04 GO:0003723 RNA binding
1.49 4.01e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.49 9.66e-05 GO:0005524 ATP binding
1.48 7.54e-08 GO:0000166 nucleotide binding
1.47 2.54e-04 GO:0032559 adenyl ribonucleotide binding
1.46 1.44e-05 GO:0032553 ribonucleotide binding
1.46 1.44e-05 GO:0032555 purine ribonucleotide binding
1.46 2.20e-05 GO:0017076 purine nucleotide binding
1.46 3.57e-04 GO:0030554 adenyl nucleotide binding
1.36 5.67e-07 GO:0003676 nucleic acid binding