Motif ID: CREB1.p2

Z-value: 2.022


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_208394823-0.324.4e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_89618928 1.001 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr19_+_54058493 0.983 NM_001079907
ZNF331
zinc finger protein 331
chr5_-_172198160 0.947 NM_004417
DUSP1
dual specificity phosphatase 1
chr1_+_36690038 0.919 THRAP3
thyroid hormone receptor associated protein 3
chr4_+_145567147 0.882 NM_022475
HHIP
hedgehog interacting protein
chr10_-_93392857 0.876 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr20_+_33292117 0.870 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr18_+_2571509 0.840 NM_006101
NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chr18_+_2571587 0.831 NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chrX_+_30671456 0.825 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr3_+_10028579 0.765 LOC442075
uncharacterized LOC442075
chr4_-_113558021 0.746 C4orf21
chromosome 4 open reading frame 21
chr18_+_76829410 0.731 ATP9B
ATPase, class II, type 9B
chr16_+_2802634 0.711 SRRM2
serine/arginine repetitive matrix 2
chr4_-_113558120 0.706 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr6_-_38607923 0.635 NM_001099272
NM_052893
BTBD9

BTB (POZ) domain containing 9

chr11_-_28129646 0.612 KIF18A
kinesin family member 18A
chr6_-_38607635 0.607 BTBD9
BTB (POZ) domain containing 9
chr1_+_162760491 0.600 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr19_+_1248548 0.590 NM_177401
MIDN
midnolin
chr1_-_186344801 0.586 TPR
translocated promoter region (to activated MET oncogene)
chr16_-_30007315 0.582 NM_001197323
NM_003609
HIRIP3

HIRA interacting protein 3

chr13_-_80912971 0.575 SPRY2
sprouty homolog 2 (Drosophila)
chr1_+_171454636 0.567 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr11_-_35547144 0.550 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_-_245025958 0.533 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr14_+_61447929 0.527 SLC38A6
solute carrier family 38, member 6
chr14_+_61447831 0.523 NM_001172702
NM_153811
SLC38A6

solute carrier family 38, member 6

chr16_+_2802683 0.518 SRRM2
serine/arginine repetitive matrix 2
chr16_+_2802656 0.510 SRRM2
serine/arginine repetitive matrix 2
chr14_+_61447949 0.501 SLC38A6
solute carrier family 38, member 6
chr11_+_12695851 0.494 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr15_+_41952641 0.493 MGA
MAX gene associated
chr22_-_44258210 0.491 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr3_-_52719514 0.491 NM_018313
PBRM1
polybromo 1
chr10_-_100027943 0.490 NM_032211
LOXL4
lysyl oxidase-like 4
chr9_-_110252045 0.489 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr1_-_15850776 0.482 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr16_+_2802673 0.473 SRRM2
serine/arginine repetitive matrix 2
chr4_+_56261763 0.456


chr4_-_104119475 0.449 NM_001813
CENPE
centromere protein E, 312kDa
chr17_-_78450247 0.446 NM_002522
NPTX1
neuronal pentraxin I
chr9_-_79520878 0.443 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr1_+_222791151 0.441 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr3_+_170075494 0.433 SKIL
SKI-like oncogene
chr19_+_49375679 0.431 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr3_+_16306666 0.427 NM_138381
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr19_+_49375638 0.425 NM_014330
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr9_-_127703294 0.424 NM_002077
GOLGA1
golgin A1
chr17_+_80186886 0.421 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr3_+_170075449 0.421 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr8_-_82024277 0.420 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr13_+_32889594 0.418 NM_000059
BRCA2
breast cancer 2, early onset
chr14_+_75179846 0.412 NM_015962
FCF1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr17_-_13505217 0.406 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr1_+_27719151 0.405 NM_005281
GPR3
G protein-coupled receptor 3
chr7_+_1200097 0.402


chr9_+_134000939 0.401 NM_005085
NUP214
nucleoporin 214kDa
chr17_-_76836852 0.401 NM_025090
USP36
ubiquitin specific peptidase 36
chrX_+_30671537 0.401 GK
glycerol kinase
chr5_-_126366068 0.399 MARCH3
membrane-associated ring finger (C3HC4) 3
chr19_+_49375677 0.398 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_+_201450730 0.397 NM_001159
AOX1
aldehyde oxidase 1
chr6_+_30524485 0.396 NM_001077497
NM_025263
PRR3

proline rich 3

chr6_-_15248886 0.391


chr17_-_685385 0.391 NM_016080
GLOD4
glyoxalase domain containing 4
chr16_+_2802605 0.390 SRRM2
serine/arginine repetitive matrix 2
chr19_-_5340700 0.389 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr12_+_132629014 0.379 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr5_-_43313492 0.378 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr4_-_54232007 0.377 NM_152540
SCFD2
sec1 family domain containing 2
chr16_-_46655262 0.376 SHCBP1
SHC SH2-domain binding protein 1
chr2_-_202645894 0.373 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr15_+_93447702 0.371 CHD2
chromodomain helicase DNA binding protein 2
chr1_-_186344389 0.371 NM_003292
TPR
translocated promoter region (to activated MET oncogene)
chr19_-_46088074 0.371 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr22_+_44319685 0.364 PNPLA3
patatin-like phospholipase domain containing 3
chr17_-_36981552 0.364 NM_017748
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr16_+_2802676 0.363 SRRM2
serine/arginine repetitive matrix 2
chr11_-_3818971 0.362 NM_005387
NM_016320
NM_139131
NM_139132
NUP98



nucleoporin 98kDa



chr12_-_132628841 0.359 NM_175066
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr16_-_4897265 0.357 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr16_-_46655303 0.355 NM_024745
SHCBP1
SHC SH2-domain binding protein 1
chr14_+_102430767 0.352 NM_001376
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr4_+_153457407 0.352 DKFZP434I0714
uncharacterized protein DKFZP434I0714
chr2_-_179343225 0.351 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr1_-_53793743 0.350 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr11_+_69455938 0.349 CCND1
cyclin D1
chr1_+_36689996 0.347 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr12_-_10766130 0.346 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr19_+_39833099 0.346 NM_018028
SAMD4B
sterile alpha motif domain containing 4B
chr9_-_140082983 0.345 ANAPC2
anaphase promoting complex subunit 2
chr3_+_197687070 0.344 NM_001136049
NM_033029
LMLN

leishmanolysin-like (metallopeptidase M8 family)

chr11_-_28129701 0.344 NM_031217
KIF18A
kinesin family member 18A
chr2_+_149632772 0.343 NM_004522
KIF5C
kinesin family member 5C
chr17_+_8152594 0.341 NM_012393
PFAS
phosphoribosylformylglycinamidine synthase
chr1_-_226187019 0.338 C1orf55
chromosome 1 open reading frame 55
chr3_+_10068123 0.335 FANCD2
Fanconi anemia, complementation group D2
chr4_-_170533536 0.335 NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr11_-_28129687 0.334 KIF18A
kinesin family member 18A
chr3_+_42977833 0.334 NM_001205272
KRBOX1
KRAB box domain containing 1
chr5_-_43313581 0.334 NM_001098272
NM_002130
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr1_-_157108132 0.332 ETV3
ets variant 3
chr17_-_1619473 0.330 MIR22HG
MIR22 host gene (non-protein coding)
chr4_+_170541728 0.329 CLCN3
chloride channel 3
chr18_-_70534809 0.324 NM_001201465
NM_138966
NETO1

neuropilin (NRP) and tolloid (TLL)-like 1

chr20_+_37377096 0.323 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr2_+_242255270 0.322 NM_001008492
NM_004404
SEPT2

septin 2

chr14_-_60337350 0.322 NM_021136
RTN1
reticulon 1
chr16_-_3930713 0.318 CREBBP
CREB binding protein
chr1_-_20812727 0.315 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr12_+_110011499 0.315 NM_000431
NM_001114185
MVK

mevalonate kinase

chr2_+_97001506 0.313 NCAPH
non-SMC condensin I complex, subunit H
chr9_-_110251754 0.312 KLF4
Kruppel-like factor 4 (gut)
chr3_+_10068139 0.312 FANCD2
Fanconi anemia, complementation group D2
chr10_-_93392744 0.312 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr5_-_133561745 0.310 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr19_-_47617008 0.309 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr16_+_89989686 0.308 NM_006086
TUBB3
tubulin, beta 3 class III
chr13_-_60737899 0.308 DIAPH3
diaphanous homolog 3 (Drosophila)
chr2_-_240964807 0.306 NM_004544
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr7_+_149571029 0.304 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr16_+_15528324 0.303 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr3_+_185303961 0.299 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_-_101395611 0.298 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr15_+_33010174 0.298 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr2_+_30670082 0.296 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr14_+_105219516 0.293 SIVA1
SIVA1, apoptosis-inducing factor
chr2_-_10588451 0.292 NM_002539
ODC1
ornithine decarboxylase 1
chrX_+_30671602 0.292 GK
glycerol kinase
chrX_+_152224765 0.290 NM_013364
PNMA3
paraneoplastic antigen MA3
chr2_+_170441102 0.287 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr8_+_37594137 0.286 ERLIN2
ER lipid raft associated 2
chr1_+_62902708 0.283 USP1
ubiquitin specific peptidase 1
chr11_-_9025531 0.283 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr6_-_38607589 0.282 BTBD9
BTB (POZ) domain containing 9
chr4_-_170533762 0.281 NM_001199397
NM_001199398
NM_001199399
NM_001199400
NM_012224
NEK1




NIMA (never in mitosis gene a)-related kinase 1




chr3_+_170075521 0.281 SKIL
SKI-like oncogene
chr8_+_37594182 0.281 NM_001003790
ERLIN2
ER lipid raft associated 2
chr3_+_44771097 0.280 NM_145044
ZNF501
zinc finger protein 501
chr20_+_39657461 0.280 NM_003286
TOP1
topoisomerase (DNA) I
chr4_-_84205897 0.279 COQ2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr10_+_85954390 0.278 NM_001171971
NM_033100
CDHR1

cadherin-related family member 1

chr10_+_93558182 0.278 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr2_-_10588273 0.276 ODC1
ornithine decarboxylase 1
chr7_+_1577118 0.275 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr2_+_109403140 0.274 NM_144978
CCDC138
coiled-coil domain containing 138
chr19_+_54057898 0.274 NM_001253801
ZNF331
zinc finger protein 331
chr14_+_101292483 0.273


chr1_-_52870058 0.273 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr10_-_49812996 0.273 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr3_+_50297644 0.272


chr2_-_217236666 0.272 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr5_+_139927182 0.272 NM_003732
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr11_-_96122984 0.271 NM_024725
CCDC82
coiled-coil domain containing 82
chr5_-_133304274 0.271 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr4_-_122744782 0.270 CCNA2
cyclin A2
chr9_-_140083010 0.270 ANAPC2
anaphase promoting complex subunit 2
chr4_+_113970784 0.270 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr3_+_44803208 0.269 NM_020242
KIF15
kinesin family member 15
chr2_+_87140905 0.267 NM_001078170
RGPD2
RANBP2-like and GRIP domain containing 2
chr15_+_66797632 0.267 ZWILCH
Zwilch, kinetochore associated, homolog (Drosophila)
chr1_-_226187027 0.267 C1orf55
chromosome 1 open reading frame 55
chr5_-_132298973 0.267 AFF4
AF4/FMR2 family, member 4
chr5_-_137090049 0.266


chr3_+_73045939 0.266 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr2_+_170440846 0.266 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr9_-_140024159 0.264


chr5_-_132299248 0.263 AFF4
AF4/FMR2 family, member 4
chr11_+_69455837 0.263 NM_053056
CCND1
cyclin D1
chr7_+_7222142 0.263 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr2_+_149632836 0.263 KIF5C
kinesin family member 5C
chr1_-_157108169 0.263 NM_005240
NM_001145312
ETV3

ets variant 3

chr15_+_41952572 0.262 NM_001080541
NM_001164273
MGA

MAX gene associated

chr17_-_76836718 0.261 USP36
ubiquitin specific peptidase 36
chr19_+_54042041 0.261 NM_001253800
ZNF331
zinc finger protein 331
chr14_+_62229062 0.260 NM_003082
SNAPC1
small nuclear RNA activating complex, polypeptide 1, 43kDa
chr16_+_2802708 0.260 SRRM2
serine/arginine repetitive matrix 2
chr8_+_38854431 0.259 NM_003816
ADAM9
ADAM metallopeptidase domain 9
chr18_+_76829391 0.259 NM_198531
ATP9B
ATPase, class II, type 9B
chr7_-_45808541 0.257 SEPT7P2
septin 7 pseudogene 2
chr6_-_163148716 0.256 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr5_-_132299263 0.256 NM_014423
AFF4
AF4/FMR2 family, member 4
chr3_-_10028512 0.254 NM_018447
TMEM111
transmembrane protein 111
chr2_-_216300444 0.253 FN1
fibronectin 1
chr14_+_50359829 0.253 ARF6
ADP-ribosylation factor 6
chr10_+_27444296 0.253 MASTL
microtubule associated serine/threonine kinase-like
chr4_-_122744978 0.253 NM_001237
CCNA2
cyclin A2
chr2_-_202645653 0.252 ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr4_+_170541690 0.252 CLCN3
chloride channel 3
chr14_+_50359816 0.252 ARF6
ADP-ribosylation factor 6
chr3_-_51533996 0.251 NM_001171904
NM_014703
VPRBP

Vpr (HIV-1) binding protein

chr3_-_156877882 0.251 CCNL1
cyclin L1
chr7_-_137686812 0.250 CREB3L2
cAMP responsive element binding protein 3-like 2
chr9_-_26947435 0.249 NM_001031689
PLAA
phospholipase A2-activating protein
chr19_+_36103616 0.247 NM_015302
HAUS5
HAUS augmin-like complex, subunit 5
chr4_+_56262051 0.246 NM_018475
TMEM165
transmembrane protein 165
chr10_+_27444263 0.245 MASTL
microtubule associated serine/threonine kinase-like
chr19_+_58694676 0.245 ZNF274
zinc finger protein 274
chr19_-_46088021 0.245 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 8.66e-15 GO:0044260 cellular macromolecule metabolic process
1.59 6.96e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 8.37e-14 GO:0044237 cellular metabolic process
1.65 1.04e-12 GO:0090304 nucleic acid metabolic process
1.31 2.05e-12 GO:0044238 primary metabolic process
1.51 3.75e-12 GO:0034641 cellular nitrogen compound metabolic process
1.49 4.86e-12 GO:0006807 nitrogen compound metabolic process
1.36 5.26e-11 GO:0043170 macromolecule metabolic process
1.26 8.85e-11 GO:0008152 metabolic process
1.65 2.75e-09 GO:0016070 RNA metabolic process
2.16 2.90e-09 GO:0006396 RNA processing
1.88 5.07e-09 GO:0007049 cell cycle
1.92 1.78e-07 GO:0022402 cell cycle process
2.00 2.74e-07 GO:0022403 cell cycle phase
1.56 4.27e-07 GO:0010467 gene expression
2.08 5.67e-07 GO:0000278 mitotic cell cycle
2.10 1.23e-06 GO:0016071 mRNA metabolic process
1.57 3.38e-06 GO:0006996 organelle organization
2.26 5.10e-06 GO:0006397 mRNA processing
1.12 8.32e-06 GO:0009987 cellular process
2.16 9.02e-06 GO:0000279 M phase
3.32 9.06e-06 GO:0006403 RNA localization
2.40 1.50e-05 GO:0000087 M phase of mitotic cell cycle
3.32 1.67e-05 GO:0050657 nucleic acid transport
3.32 1.67e-05 GO:0050658 RNA transport
3.32 1.67e-05 GO:0051236 establishment of RNA localization
3.37 3.71e-05 GO:0051028 mRNA transport
3.05 4.21e-05 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.37 4.47e-05 GO:0000280 nuclear division
2.37 4.47e-05 GO:0007067 mitosis
2.33 5.95e-05 GO:0008380 RNA splicing
2.66 6.29e-05 GO:0000375 RNA splicing, via transesterification reactions
2.66 9.68e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.66 9.68e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
2.30 1.28e-04 GO:0048285 organelle fission
1.55 3.67e-04 GO:0033036 macromolecule localization
1.72 5.28e-04 GO:0046907 intracellular transport
1.30 8.31e-04 GO:0071840 cellular component organization or biogenesis
1.54 1.11e-03 GO:0051641 cellular localization
1.34 2.03e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.83 4.51e-03 GO:0006974 response to DNA damage stimulus
2.02 4.75e-03 GO:0051301 cell division
1.54 8.88e-03 GO:0008104 protein localization
1.62 1.03e-02 GO:0033554 cellular response to stress
1.79 1.06e-02 GO:0044265 cellular macromolecule catabolic process
1.27 1.33e-02 GO:0016043 cellular component organization
1.72 1.37e-02 GO:0051276 chromosome organization
1.51 1.71e-02 GO:0051649 establishment of localization in cell
1.58 2.01e-02 GO:0045184 establishment of protein localization
1.49 2.53e-02 GO:0044248 cellular catabolic process
1.39 2.71e-02 GO:0009059 macromolecule biosynthetic process
1.39 3.27e-02 GO:0034645 cellular macromolecule biosynthetic process
1.30 4.16e-02 GO:0044267 cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 1.55e-32 GO:0044424 intracellular part
1.23 1.43e-31 GO:0005622 intracellular
1.32 4.28e-28 GO:0043231 intracellular membrane-bounded organelle
1.32 6.73e-28 GO:0043227 membrane-bounded organelle
1.27 1.36e-25 GO:0043229 intracellular organelle
1.27 2.91e-25 GO:0043226 organelle
1.46 5.12e-25 GO:0044422 organelle part
1.46 1.78e-24 GO:0044446 intracellular organelle part
1.87 4.14e-24 GO:0044428 nuclear part
1.90 3.06e-21 GO:0031981 nuclear lumen
1.42 7.76e-21 GO:0005634 nucleus
1.76 2.00e-19 GO:0070013 intracellular organelle lumen
1.74 8.75e-19 GO:0043233 organelle lumen
1.73 1.09e-18 GO:0031974 membrane-enclosed lumen
1.96 2.75e-16 GO:0005654 nucleoplasm
1.24 6.53e-14 GO:0005737 cytoplasm
1.31 1.81e-12 GO:0044444 cytoplasmic part
1.36 1.98e-07 GO:0032991 macromolecular complex
1.41 3.51e-07 GO:0043228 non-membrane-bounded organelle
1.41 3.51e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.48 8.11e-07 GO:0005829 cytosol
2.06 1.15e-06 GO:0005730 nucleolus
1.96 5.47e-06 GO:0005694 chromosome
1.06 1.51e-05 GO:0005623 cell
1.06 2.48e-05 GO:0044464 cell part
1.71 2.81e-04 GO:0044451 nucleoplasm part
1.72 5.09e-04 GO:0015630 microtubule cytoskeleton
1.31 5.18e-04 GO:0043234 protein complex
1.87 6.63e-04 GO:0044427 chromosomal part
1.35 2.28e-03 GO:0031090 organelle membrane
2.22 2.35e-03 GO:0016604 nuclear body
1.77 2.81e-03 GO:0030529 ribonucleoprotein complex
3.07 6.56e-03 GO:0071013 catalytic step 2 spliceosome
2.52 7.04e-03 GO:0005681 spliceosomal complex
1.92 7.25e-03 GO:0005815 microtubule organizing center
2.59 9.67e-03 GO:0016607 nuclear speck
2.38 1.95e-02 GO:0000775 chromosome, centromeric region
1.36 2.42e-02 GO:0012505 endomembrane system

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 5.45e-10 GO:0005488 binding
1.23 2.14e-09 GO:0005515 protein binding
1.48 7.54e-08 GO:0000166 nucleotide binding
3.76 1.73e-07 GO:0008026 ATP-dependent helicase activity
3.76 1.73e-07 GO:0070035 purine NTP-dependent helicase activity
1.36 5.67e-07 GO:0003676 nucleic acid binding
3.25 6.90e-07 GO:0004386 helicase activity
1.83 1.12e-06 GO:0016462 pyrophosphatase activity
1.85 1.37e-06 GO:0017111 nucleoside-triphosphatase activity
1.83 1.39e-06 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.82 1.73e-06 GO:0016817 hydrolase activity, acting on acid anhydrides
1.49 4.01e-06 GO:0035639 purine ribonucleoside triphosphate binding
2.21 1.43e-05 GO:0016887 ATPase activity
1.46 1.44e-05 GO:0032553 ribonucleotide binding
1.46 1.44e-05 GO:0032555 purine ribonucleotide binding
1.46 2.20e-05 GO:0017076 purine nucleotide binding
1.49 9.66e-05 GO:0005524 ATP binding
1.22 1.39e-04 GO:0003824 catalytic activity
2.26 1.43e-04 GO:0042623 ATPase activity, coupled
1.68 1.83e-04 GO:0003723 RNA binding
1.47 2.54e-04 GO:0032559 adenyl ribonucleotide binding
1.46 3.57e-04 GO:0030554 adenyl nucleotide binding
3.37 1.50e-02 GO:0004221 ubiquitin thiolesterase activity