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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: CRX.p2

Z-value: 1.270

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_61747956	2.185		TMEM30B	transmembrane protein 30B
chr20_+_9288446	2.071	NM_000933	PLCB4	phospholipase C, beta 4
chr18_+_29027731	1.977	NM_001944	DSG3	desmoglein 3
chr11_-_102668892	1.847	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr3_+_122044010	1.594	NM_005213	CSTA	cystatin A (stefin A)
chr7_+_26400503	1.566	NM_001199837	SNX10	sorting nexin 10
chr14_-_61748510	1.472	NM_001017970	TMEM30B	transmembrane protein 30B
chr1_+_31883020	1.462	NM_001199037	SERINC2	serine incorporator 2
chr20_+_43803539	1.326	NM_002638	PI3	peptidase inhibitor 3, skin-derived
chr1_+_86889768	1.253	NM_006536	CLCA2	chloride channel accessory 2
chr8_+_86376130	1.216	NM_000067	CA2	carbonic anhydrase II
chr5_+_140254930	1.181	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr2_-_216003068	1.172	NM_173076	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr15_+_40509628	1.168	NM_001128628 NM_001128629	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr6_-_11779279	1.161	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr2_-_161056762	1.160		ITGB6	integrin, beta 6
chr10_-_116418056	1.138	NM_002313	ABLIM1	actin binding LIM protein 1
chr9_+_12693385	1.064	NM_000550	TYRP1	tyrosinase-related protein 1
chr2_-_161056573	1.051	NM_000888	ITGB6	integrin, beta 6
chr8_-_80993009	1.041	NM_001025252	TPD52	tumor protein D52
chr2_+_102608305	0.993	NM_004633	IL1R2	interleukin 1 receptor, type II
chr5_+_36608430	0.985	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_71148063	0.949		PTPRR	protein tyrosine phosphatase, receptor type, R
chrX_-_24690740	0.886	NM_001163264	PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chr11_-_108464344	0.831	NM_015065	EXPH5	exophilin 5
chr4_+_40198526	0.824	NM_004310	RHOH	ras homolog gene family, member H
chr11_+_117947785	0.815		TMPRSS4	transmembrane protease, serine 4
chr14_+_21510384	0.809	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr1_+_101702561	0.791		S1PR1	sphingosine-1-phosphate receptor 1
chr8_+_32579350	0.786	NM_001159996	NRG1	neuregulin 1
chr3_+_50306578	0.785		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr10_-_118680978	0.777		KIAA1598	KIAA1598
chr17_-_39274587	0.753	NM_033059	KRTAP4-11	keratin associated protein 4-11
chr1_+_153330329	0.751	NM_002965	S100A9	S100 calcium binding protein A9
chr2_+_113885137	0.716	NM_173842	IL1RN	interleukin 1 receptor antagonist
chr17_-_74483806	0.716	NM_001005498	RHBDF2	rhomboid 5 homolog 2 (Drosophila)
chrX_+_17653412	0.711	NM_001136024	NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr19_-_51530781	0.688	NM_144947	KLK11	kallikrein-related peptidase 11
chr5_+_70944968	0.687		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr3_+_136676706	0.683	NM_144717	IL20RB	interleukin 20 receptor beta
chr3_+_50306305	0.675		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr12_+_8975149	0.672	NM_144670	A2ML1	alpha-2-macroglobulin-like 1
chr17_-_39280377	0.642	NM_031854	KRTAP4-12	keratin associated protein 4-12
chr3_+_160394946	0.641	NM_025047	ARL14	ADP-ribosylation factor-like 14
chr14_+_23842017	0.633	NM_172314 NM_022789	IL25	interleukin 25
chr18_+_55714457	0.630	NM_001144964	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr4_+_88896868	0.629		SPP1	secreted phosphoprotein 1
chr4_+_88896838	0.624		SPP1	secreted phosphoprotein 1
chr4_+_88896899	0.619		SPP1	secreted phosphoprotein 1
chr1_+_32042085	0.612	NM_001204414 NM_022164	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr3_-_124842442	0.609		SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr2_-_75796847	0.606	NM_032181	FAM176A	family with sequence similarity 176, member A
chr17_+_54230835	0.602	NM_153228	ANKFN1	ankyrin-repeat and fibronectin type III domain containing 1
chr11_-_102651321	0.602	NM_002425	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr1_-_28520379	0.588	NM_001164721 NM_001164722	PTAFR	platelet-activating factor receptor
chr12_-_50616425	0.587	NM_001113547	LIMA1	LIM domain and actin binding 1
chrX_-_117107700	0.587	NM_033495 NM_001168300	KLHL13	kelch-like 13 (Drosophila)
chr2_-_215896809	0.583	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_204329043	0.576	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr2_-_38525527	0.576		ATL2	atlastin GTPase 2
chr12_-_89746244	0.568	NM_001946 NM_022652	DUSP6	dual specificity phosphatase 6
chr18_+_61254533	0.567	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr1_-_217113007	0.556	NM_001243512 NM_001243513 NM_001243510 NM_001243511	ESRRG	estrogen-related receptor gamma
chr1_+_156119734	0.553	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_+_47624222	0.551	NM_153839	GPR111	G protein-coupled receptor 111
chr20_+_44637539	0.538	NM_004994	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chrX_+_102585113	0.530	NM_152278	TCEAL7	transcription elongation factor A (SII)-like 7
chr6_-_136788012	0.530	NM_001198615	MAP7	microtubule-associated protein 7
chr12_-_89746238	0.526		DUSP6	dual specificity phosphatase 6
chr2_-_165424993	0.513		GRB14	growth factor receptor-bound protein 14
chr3_+_39371196	0.509	NM_005201	CCR8	chemokine (C-C motif) receptor 8
chr8_-_57233240	0.507	NM_138969	SDR16C5	short chain dehydrogenase/reductase family 16C, member 5
chr9_-_114090712	0.498	NM_205859	OR2K2	olfactory receptor, family 2, subfamily K, member 2
chr10_+_123754141	0.496		TACC2	transforming, acidic coiled-coil containing protein 2
chr16_-_48266181	0.491	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr9_+_116638544	0.490	NM_133374	ZNF618	zinc finger protein 618
chr7_-_143105897	0.489	NM_005232	EPHA1	EPH receptor A1
chr5_+_140261792	0.483	NM_018904 NM_031865	PCDHA13	protocadherin alpha 13
chr7_+_18126543	0.482	NM_001204144	HDAC9	histone deacetylase 9
chr22_+_32753853	0.482	NM_001098535	RFPL3	ret finger protein-like 3
chr20_+_9198036	0.481	NM_182797	PLCB4	phospholipase C, beta 4
chr14_+_21525980	0.479	NM_138331	RNASE8	ribonuclease, RNase A family, 8
chr6_-_41130820	0.475		TREM2	triggering receptor expressed on myeloid cells 2
chr11_-_36619776	0.474	NM_000536 NM_001243785 NM_001243786	RAG2	recombination activating gene 2
chr1_-_93342706	0.465	NM_001252271	FAM69A	family with sequence similarity 69, member A
chrM_+_8857	0.463
chr1_-_156786500	0.462	NM_001161441 NM_001161442 NM_001161444 NM_003975	SH2D2A	SH2 domain containing 2A
chr2_+_113885145	0.459		IL1RN	interleukin 1 receptor antagonist
chr6_-_3272349	0.457		SLC22A23	solute carrier family 22, member 23
chr21_-_43187265	0.456		RIPK4	receptor-interacting serine-threonine kinase 4
chr10_-_14816895	0.448	NM_031453	FAM107B	family with sequence similarity 107, member B
chr1_+_81771844	0.440		LPHN2	latrophilin 2
chrX_+_129139163	0.432	NM_021946	BCORL1	BCL6 corepressor-like 1
chrM_+_9217	0.419
chr22_+_45148437	0.419	NM_001017526 NM_001198726 NM_181335	ARHGAP8	Rho GTPase activating protein 8
chr19_+_35607218	0.417		FXYD3	FXYD domain containing ion transport regulator 3
chr18_+_33234532	0.414	NM_020474	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr6_-_138893666	0.410	NM_020464	NHSL1	NHS-like 1
chr12_-_31479084	0.410		FAM60A	family with sequence similarity 60, member A
chr2_-_165478357	0.405	NM_004490	GRB14	growth factor receptor-bound protein 14
chr12_+_20848288	0.402	NM_001145945 NM_001145946 NM_001145944 NM_017435	SLCO1C1	solute carrier organic anion transporter family, member 1C1
chr12_+_29376596	0.400	NM_018099	FAR2	fatty acyl CoA reductase 2
chr11_+_45943171	0.400	NM_152312	GYLTL1B	glycosyltransferase-like 1B
chr11_-_102668822	0.399		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr1_-_168513201	0.399	NM_003175	XCL1 XCL2	chemokine (C motif) ligand 1 chemokine (C motif) ligand 2
chr6_+_130339715	0.394	NM_001007102 NM_032438	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr1_+_160765927	0.389	NM_001033667 NM_002348	LY9	lymphocyte antigen 9
chrX_-_131573638	0.382	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chr11_-_85425790	0.379	NM_032379	SYTL2	synaptotagmin-like 2
chr11_-_118123001	0.374	NM_198275	MPZL3	myelin protein zero-like 3
chr6_+_90604185	0.373	NM_032602	GJA10	gap junction protein, alpha 10, 62kDa
chr18_-_13915534	0.372	NM_000529	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr10_-_86001197	0.370	NM_015613	LRIT1	leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr20_+_42984338	0.370	NM_001030003 NM_001030004 NM_175914	HNF4A	hepatocyte nuclear factor 4, alpha
chr9_-_112191105	0.366	NM_001145371 NM_001145372	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr19_-_51512803	0.364	NM_012315	KLK9	kallikrein-related peptidase 9
chr3_+_189507448	0.360	NM_001114980 NM_001114981 NM_001114982	TP63	tumor protein p63
chr6_+_4890225	0.356	NM_001143971	CDYL	chromodomain protein, Y-like
chrX_+_105412297	0.355	NM_001171020 NM_152423	MUM1L1	melanoma associated antigen (mutated) 1-like 1
chr21_+_39628869	0.355	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_34642587	0.352	NM_001206615 NM_012153	EHF	ets homologous factor
chr9_-_99801924	0.352	NM_001201575	CTSL2	cathepsin L2
chr14_-_24777160	0.351		CIDEB	cell death-inducing DFFA-like effector b
chrX_-_117119282	0.351	NM_001168299	KLHL13	kelch-like 13 (Drosophila)
chr1_-_153067000	0.348	NM_001024209	SPRR2E	small proline-rich protein 2E
chr14_-_24777153	0.348		CIDEB	cell death-inducing DFFA-like effector b
chr1_+_26872306	0.346		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr13_+_73633097	0.343	NM_001730	KLF5	Kruppel-like factor 5 (intestinal)
chr12_-_89745997	0.342		DUSP6	dual specificity phosphatase 6
chr12_-_31479120	0.340	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr4_+_76481257	0.340	NM_001206981 NM_178497	C4orf26	chromosome 4 open reading frame 26
chr6_-_33754712	0.339	NM_001143944	LEMD2	LEM domain containing 2
chr15_-_90222572	0.339	NM_001145311 NM_002666	PLIN1	perilipin 1
chr5_+_131409484	0.333	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr14_+_96671015	0.331	NM_000623	BDKRB2	bradykinin receptor B2
chr8_-_66701175	0.331	NM_002603	PDE7A	phosphodiesterase 7A
chr1_-_177133950	0.327	NM_004319 NM_207108	ASTN1	astrotactin 1
chr1_+_145413190	0.325	NM_145277 NM_202004 NM_213652 NM_213653	HFE2	hemochromatosis type 2 (juvenile)
chr11_+_117947726	0.322	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr14_-_24777184	0.321		CIDEB	cell death-inducing DFFA-like effector b
chr2_+_113875469	0.320	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chrX_+_55649832	0.319	NM_198451	FOXR2	forkhead box R2
chr17_+_56315786	0.318	NM_001160102 NM_006151	LPO	lactoperoxidase
chr16_+_57728711	0.317	NM_032269	CCDC135	coiled-coil domain containing 135
chr5_-_77844975	0.316		LHFPL2	lipoma HMGIC fusion partner-like 2
chr12_+_95676175	0.315		VEZT	vezatin, adherens junctions transmembrane protein
chr18_-_44561967	0.312	NM_016427	TCEB3B	transcription elongation factor B polypeptide 3B (elongin A2)
chr11_+_112047088	0.311	NM_001037290	BCO2	beta-carotene oxygenase 2
chrM_+_9182	0.310
chr12_-_91452130	0.310	NM_007035	KERA	keratocan
chr5_-_33984688	0.309	NM_001012509 NM_016180	SLC45A2	solute carrier family 45, member 2
chr13_+_78109808	0.309	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr6_-_52109226	0.306	NM_052872	IL17F	interleukin 17F
chr9_-_5304579	0.305	NM_005059 NM_134441	RLN2	relaxin 2
chr12_-_52604488	0.304	NM_001242696	LOC283403	uncharacterized LOC283403
chr3_-_27498244	0.304	NM_003615	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr21_+_43619798	0.303	NM_207627 NM_207628	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr6_+_7107799	0.294	NM_001168344	RREB1	ras responsive element binding protein 1
chr6_-_42110714	0.292	NM_001164446	C6orf132	chromosome 6 open reading frame 132
chr5_-_148442606	0.292	NM_024577	SH3TC2	SH3 domain and tetratricopeptide repeats 2
chr4_+_187070326	0.290	NM_001006655	FAM149A	family with sequence similarity 149, member A
chr7_-_37025696	0.285		ELMO1	engulfment and cell motility 1
chr17_-_54893249	0.283	NM_001085430	C17orf67	chromosome 17 open reading frame 67
chr12_-_31479038	0.281		FAM60A	family with sequence similarity 60, member A
chr8_-_42234562	0.279	NM_014420	DKK4	dickkopf homolog 4 (Xenopus laevis)
chr21_+_39628663	0.276	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr4_-_47983430	0.276	NM_001142564	CNGA1	cyclic nucleotide gated channel alpha 1
chr2_-_180871779	0.274	NM_020943	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr2_+_234590583	0.272	NM_019077	UGT1A7	UDP glucuronosyltransferase 1 family, polypeptide A7
chr7_+_115863004	0.271	NM_152829	TES	testis derived transcript (3 LIM domains)
chr7_+_128580725	0.271	NM_001098627	IRF5	interferon regulatory factor 5
chr1_-_6662681	0.271		KLHL21	kelch-like 21 (Drosophila)
chr17_-_34266359	0.270	NM_020426	LYZL6	lysozyme-like 6
chr1_+_26872342	0.270	NM_001006665	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr8_-_127570465	0.268		FAM84B	family with sequence similarity 84, member B
chr1_+_154293568	0.268	NM_080429	AQP10	aquaporin 10
chr12_-_54778456	0.267	NM_015481	ZNF385A	zinc finger protein 385A
chr10_+_99332197	0.266	NM_001129981 NM_020349	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)
chr5_+_55149149	0.264	NM_001242636 NM_001242639	IL31RA	interleukin 31 receptor A
chr2_-_26101329	0.263		ASXL2	additional sex combs like 2 (Drosophila)
chr8_-_110693233	0.262	NM_001099745 NM_001099746	SYBU	syntabulin (syntaxin-interacting)
chr9_-_124984018	0.262	NM_001242335	LHX6	LIM homeobox 6
chrX_-_106362050	0.262	NM_001171080 NM_018301	RBM41	RNA binding motif protein 41
chr12_-_23737507	0.261	NM_178010	SOX5	SRY (sex determining region Y)-box 5
chr5_+_140430960	0.260	NM_013340	PCDHB1	protocadherin beta 1
chr6_-_41130921	0.259	NM_018965	TREM2	triggering receptor expressed on myeloid cells 2
chr19_+_35606731	0.259	NM_001136007 NM_001136008 NM_001136009 NM_001136010 NM_001136011 NM_001136012 NM_005971 NM_021910	FXYD3	FXYD domain containing ion transport regulator 3
chrM_+_8364	0.259
chrM_+_9725	0.258
chr4_+_110749149	0.255	NM_006583	RRH	retinal pigment epithelium-derived rhodopsin homolog
chr7_+_116660263	0.255		ST7	suppression of tumorigenicity 7
chr4_-_190948396	0.254	NM_001199232 NM_001005217	LOC100288255 FRG2	FSHD region gene 2-like FSHD region gene 2
chr5_-_137071703	0.253	NM_017415	KLHL3	kelch-like 3 (Drosophila)
chr16_-_10674443	0.253	NM_001424	EMP2	epithelial membrane protein 2
chr12_-_52761254	0.253	NM_002283	KRT85	keratin 85
chrM_+_10704	0.252
chr17_+_7623038	0.252	NM_020877	DNAH2	dynein, axonemal, heavy chain 2
chr1_-_116311330	0.251		CASQ2	calsequestrin 2 (cardiac muscle)
chr13_-_46756291	0.251		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr20_-_44538654	0.251		PLTP	phospholipid transfer protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
11.13	3.29e-02	GO:0007210	serotonin receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.29	4.86e-02	GO:0005576	extracellular region

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
13.35	2.05e-02	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity