Motif ID: CUUUGGU

Z-value: 0.721


Mature miRNA associated with seed CUUUGGU:

NamemiRBase Accession
hsa-miR-9 MIMAT0000441



Activity profile for motif CUUUGGU.

activity profile for motif CUUUGGU


Sorted Z-values histogram for motif CUUUGGU

Sorted Z-values for motif CUUUGGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CUUUGGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_69924407 0.706 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr16_+_68771192 0.689 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_-_46384 0.498 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr1_+_155100304 0.487 NM_004428
NM_182685
EFNA1

ephrin-A1

chr6_+_130758261 0.448 NM_052913
TMEM200A
transmembrane protein 200A
chr4_+_77356252 0.439 NM_020859
SHROOM3
shroom family member 3
chr6_-_136847743 0.437 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr6_-_136871956 0.434 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr6_-_136788012 0.422 NM_001198615
MAP7
microtubule-associated protein 7
chr9_+_115913227 0.410 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr6_-_136847078 0.409 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr15_+_40509628 0.394 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr11_-_79151694 0.391 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr15_+_40532034 0.372 NM_020168
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr6_+_150464156 0.367 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr1_+_117452359 0.336 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr6_+_106534188 0.334 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr14_-_23652840 0.333 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr1_+_109792640 0.327 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr9_-_117880411 0.313 NM_002160
TNC
tenascin C
chr9_-_107690526 0.312 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr14_-_23623493 0.309 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr6_+_106546736 0.302 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr8_+_95653340 0.300 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr10_+_23983674 0.296 NM_001098500
KIAA1217
KIAA1217
chrX_+_105412297 0.289 NM_001171020
NM_152423
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr2_-_20425166 0.281 NM_001006946
SDC1
syndecan 1
chr20_-_14318200 0.279 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr18_+_29027731 0.278 NM_001944
DSG3
desmoglein 3
chr9_-_23826062 0.275 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr17_-_39942937 0.271 NM_002230
NM_021991
JUP

junction plakoglobin

chr2_-_235405692 0.270 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr15_-_72612497 0.268 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr2_+_173292306 0.267 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr15_-_72612247 0.266 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr9_-_23821842 0.264 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_+_32042085 0.263 NM_001204414
NM_022164
TINAGL1

tubulointerstitial nephritis antigen-like 1

chrX_-_100914816 0.263 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr2_-_20424627 0.262 NM_002997
SDC1
syndecan 1
chr11_+_33563772 0.261 NM_012194
C11orf41
chromosome 11 open reading frame 41
chrX_+_105937067 0.255 NM_024539
RNF128
ring finger protein 128
chr9_-_23821477 0.252 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr8_-_22550708 0.251 NM_004430
EGR3
early growth response 3
chr1_+_32043745 0.249 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr11_+_13030879 0.245 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr17_+_73717515 0.241 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr8_-_134309448 0.239 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr8_-_22550057 0.237 NM_001199881
EGR3
early growth response 3
chrX_+_105969875 0.237 NM_194463
RNF128
ring finger protein 128
chr10_-_105614952 0.237 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr8_-_22549901 0.235 NM_001199880
EGR3
early growth response 3
chr17_-_31203889 0.226 NM_015194
MYO1D
myosin ID
chr9_-_135996287 0.221 NM_006266
RALGDS
ral guanine nucleotide dissociation stimulator
chr6_+_1312674 0.221 NM_033260
FOXQ1
forkhead box Q1
chr21_+_46875402 0.219 NM_030582
COL18A1
collagen, type XVIII, alpha 1
chr6_+_116692098 0.219 NM_013352
DSE
dermatan sulfate epimerase
chr21_+_46825001 0.219 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr3_+_36421944 0.218 NM_003149
STAC
SH3 and cysteine rich domain
chr9_+_116638544 0.212 NM_133374
ZNF618
zinc finger protein 618
chr2_+_112812799 0.211 NM_032824
TMEM87B
transmembrane protein 87B
chr12_+_5019048 0.207 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr12_-_123594974 0.205 NM_020845
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr2_+_97426571 0.202 NM_020184
CNNM4
cyclin M4
chr8_-_42397048 0.201 NM_006749
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr17_+_73720775 0.200 NM_001005619
ITGB4
integrin, beta 4
chr17_-_47841517 0.199 NM_030802
FAM117A
family with sequence similarity 117, member A
chr15_+_74833517 0.199 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr15_-_72598655 0.196 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr10_-_50970321 0.195 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr17_-_10741398 0.195 NM_001101387
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chrX_-_25034064 0.194 NM_139058
ARX
aristaless related homeobox
chr10_-_14816895 0.192 NM_031453
FAM107B
family with sequence similarity 107, member B
chr9_-_136024522 0.191 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr4_+_41937105 0.189 NM_018126
TMEM33
transmembrane protein 33
chr21_+_33245304 0.187 NM_014586
HUNK
hormonally up-regulated Neu-associated kinase
chr8_+_28559143 0.187 NM_001440
EXTL3
exostoses (multiple)-like 3
chr8_-_21998994 0.186 NM_025232
REEP4
receptor accessory protein 4
chr6_-_82462374 0.183 NM_017633
FAM46A
family with sequence similarity 46, member A
chr12_-_58026846 0.180 NM_001478
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr1_-_41131323 0.180 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr3_+_111451326 0.179 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr17_-_41910439 0.178 NM_001932
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr3_+_193853930 0.178 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr1_-_27481400 0.177 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr7_-_138665853 0.177 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr2_+_26568900 0.177 NM_033505
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr17_+_72244504 0.176 NM_052869
TTYH2
tweety homolog 2 (Drosophila)
chr6_+_19837599 0.176 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr10_-_113943467 0.174 NM_001244949
NM_020918
GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

chr5_-_49737216 0.174 NM_198449
EMB
embigin
chr15_+_94841429 0.172 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr13_+_73633097 0.171 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr9_+_131843378 0.170 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr1_-_19282773 0.168 NM_001136265
IFFO2
intermediate filament family orphan 2
chr17_-_6459746 0.168 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr1_-_48462561 0.165 NM_001194986
LOC388630
UPF0632 protein A
chr16_-_17564737 0.163 NM_022166
XYLT1
xylosyltransferase I
chr10_+_24497719 0.161 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr14_-_78083109 0.161 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr13_-_76055872 0.159 NM_014832
TBC1D4
TBC1 domain family, member 4
chr1_-_109935869 0.159 NM_001205228
SORT1
sortilin 1
chr2_+_121103670 0.158 NM_002193
INHBB
inhibin, beta B
chr1_-_109940497 0.158 NM_002959
SORT1
sortilin 1
chr13_+_113344354 0.156 NM_015205
NM_032189
ATP11A

ATPase, class VI, type 11A

chr17_+_12569206 0.155 NM_001146312
NM_153604
MYOCD

myocardin

chr1_+_62208091 0.155 NM_176877
INADL
InaD-like (Drosophila)
chr6_-_107435635 0.154 NM_001080450
BEND3
BEN domain containing 3
chr3_-_129612371 0.154 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr13_-_41240607 0.154 NM_002015
FOXO1
forkhead box O1
chr5_+_10353802 0.154 NM_005885
MARCH6
membrane-associated ring finger (C3HC4) 6
chr5_+_149109814 0.153 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr14_+_70078309 0.153 NM_014734
KIAA0247
KIAA0247
chr3_-_87040246 0.152 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr9_+_131799212 0.150 NM_032809
FAM73B
family with sequence similarity 73, member B
chr1_+_65613211 0.147 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr6_-_42419782 0.146 NM_033502
TRERF1
transcriptional regulating factor 1
chr3_+_57994087 0.146 NM_001164317
NM_001164318
NM_001164319
NM_001457
FLNB



filamin B, beta



chr12_+_56521953 0.143 NM_001184796
NM_015292
ESYT1

extended synaptotagmin-like protein 1

chr5_+_135364583 0.143 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr22_+_21771661 0.141 NM_015094
HIC2
hypermethylated in cancer 2
chr1_+_65613771 0.141 NM_013410
AK4
adenylate kinase 4
chr1_+_37940074 0.140 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr5_-_141257943 0.140 NM_002587
NM_032420
PCDH1

protocadherin 1

chr3_+_43328001 0.140 NM_001100594
NM_017719
SNRK

SNF related kinase

chr2_+_46524448 0.140 NM_001430
EPAS1
endothelial PAS domain protein 1
chr13_+_96329392 0.139 NM_006260
DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr12_-_89746244 0.138 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr17_+_72209500 0.137 NM_032646
TTYH2
tweety homolog 2 (Drosophila)
chr15_+_73344824 0.136 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr7_-_139876718 0.135 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr6_+_80340971 0.134 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr11_-_87908551 0.134 NM_022337
RAB38
RAB38, member RAS oncogene family
chr20_-_6104056 0.133 NM_017671
FERMT1
fermitin family member 1
chr4_+_108745718 0.132 NM_001136258
SGMS2
sphingomyelin synthase 2
chr5_+_175875355 0.131 NM_014613
FAF2
Fas associated factor family member 2
chr10_+_119000583 0.131 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr2_-_38604430 0.130 NM_001135673
NM_022374
ATL2

atlastin GTPase 2

chr5_+_149151502 0.130 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr4_+_141445311 0.129 NM_153702
ELMOD2
ELMO/CED-12 domain containing 2
chr11_+_44785975 0.128 NM_130783
TSPAN18
tetraspanin 18
chr14_-_95786095 0.127 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr3_-_129599220 0.127 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr1_+_169075869 0.126 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_-_102861305 0.125 NM_015051
ERP44
endoplasmic reticulum protein 44
chr10_+_101419169 0.125 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr6_-_80656870 0.125 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chr22_+_47022657 0.125 NM_015124
GRAMD4
GRAM domain containing 4
chr3_+_111578026 0.125 NM_001134438
NM_145753
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr7_+_23636970 0.124 NM_138771
CCDC126
coiled-coil domain containing 126
chr8_-_103424897 0.123 NM_015902
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr1_+_116185249 0.123 NM_001172412
VANGL1
vang-like 1 (van gogh, Drosophila)
chr20_-_41818464 0.122 NM_007050
NM_133170
PTPRT

protein tyrosine phosphatase, receptor type, T

chr1_-_6321034 0.122 NM_207370
GPR153
G protein-coupled receptor 153
chr16_+_71392615 0.122 NM_001740
NM_007088
CALB2

calbindin 2

chr2_+_191002485 0.121 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr1_-_169455099 0.121 NM_006996
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr11_+_66886735 0.121 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr13_-_30169795 0.121 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr17_+_1959512 0.120 NM_001098202
HIC1
hypermethylated in cancer 1
chr22_+_38302085 0.120 NM_033386
MICALL1
MICAL-like 1
chr2_+_48541767 0.120 NM_002158
FOXN2
forkhead box N2
chr2_+_109335906 0.119 NM_006267
RANBP2
RAN binding protein 2
chr2_+_7057471 0.119 NM_014746
RNF144A
ring finger protein 144A
chrX_+_68725077 0.118 NM_015686
FAM155B
family with sequence similarity 155, member B
chr15_+_69591272 0.116 NM_017705
PAQR5
progestin and adipoQ receptor family member V
chr1_-_184943673 0.116 NM_052966
FAM129A
family with sequence similarity 129, member A
chr12_+_38710556 0.115 NM_001013620
ALG10B
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)
chr11_+_60681370 0.113 NM_024092
TMEM109
transmembrane protein 109
chr2_-_1748285 0.111 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr1_+_107682628 0.111 NM_001113226
NM_001113228
NM_014917
NTNG1


netrin G1


chr4_+_86699846 0.110 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr1_-_175161832 0.110 NM_001162895
NM_014656
NM_001162893
NM_001162894
KIAA0040



KIAA0040



chr1_+_116184573 0.110 NM_001172411
NM_138959
VANGL1

vang-like 1 (van gogh, Drosophila)

chr2_+_203499819 0.110 NM_173511
FAM117B
family with sequence similarity 117, member B
chr18_+_23806385 0.110 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr2_+_191014971 0.110 NM_001042520
C2orf88
chromosome 2 open reading frame 88
chr10_-_125851850 0.110 NM_014863
NM_015892
CHST15

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

chr6_-_128841432 0.109 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr11_-_113345841 0.109 NM_000795
NM_016574
DRD2

dopamine receptor D2

chr19_+_41222915 0.108 NM_025194
ITPKC
inositol-trisphosphate 3-kinase C
chr3_-_32544358 0.108 NM_017801
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr9_-_34590137 0.108 NM_001207011
CNTFR
ciliary neurotrophic factor receptor
chr14_-_104313730 0.106 NM_015316
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr9_-_34589679 0.106 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr4_+_86396251 0.105 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr1_-_108507474 0.105 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr3_-_107809754 0.103 NM_001777
NM_198793
CD47

CD47 molecule

chr7_-_158622202 0.103 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr9_+_131102786 0.102 NM_005094
SLC27A4
solute carrier family 27 (fatty acid transporter), member 4
chr14_-_95599794 0.101 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr10_+_71211215 0.101 NM_012339
TSPAN15
tetraspanin 15
chr11_+_94501503 0.101 NM_130847
AMOTL1
angiomotin like 1
chr2_+_191045588 0.101 NM_001042519
NM_032321
C2orf88

chromosome 2 open reading frame 88

chr1_+_236849753 0.101 NM_001103
ACTN2
actinin, alpha 2
chr4_+_108814419 0.101 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr3_-_53080038 0.100 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr4_+_30721865 0.100 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr5_-_175964223 0.099 NM_014901
RNF44
ring finger protein 44
chr14_-_55369163 0.098 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr1_-_155948317 0.098 NM_001162383
NM_001162384
ARHGEF2

Rho/Rac guanine nucleotide exchange factor (GEF) 2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.09 5.38e-05 GO:0009100 glycoprotein metabolic process
3.17 4.20e-04 GO:0009101 glycoprotein biosynthetic process
1.93 1.48e-03 GO:0055085 transmembrane transport
1.36 4.20e-03 GO:0032502 developmental process
1.36 1.12e-02 GO:0007275 multicellular organismal development
1.13 1.22e-02 GO:0009987 cellular process
1.52 1.64e-02 GO:0006464 protein modification process
1.39 2.85e-02 GO:0048731 system development
1.36 2.90e-02 GO:0048856 anatomical structure development
2.89 4.22e-02 GO:0070085 glycosylation
2.25 4.82e-02 GO:0018193 peptidyl-amino acid modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.40 1.32e-12 GO:0044425 membrane part
1.34 2.91e-12 GO:0016020 membrane
1.40 1.21e-09 GO:0031224 intrinsic to membrane
1.40 4.49e-09 GO:0016021 integral to membrane
1.68 2.45e-05 GO:0012505 endomembrane system
1.55 4.16e-05 GO:0044459 plasma membrane part
1.34 3.27e-04 GO:0005886 plasma membrane
1.33 4.29e-04 GO:0071944 cell periphery
1.98 1.84e-03 GO:0030054 cell junction
2.06 4.39e-03 GO:0000139 Golgi membrane
1.94 4.71e-03 GO:0044431 Golgi apparatus part
1.45 5.11e-03 GO:0031090 organelle membrane
1.59 9.32e-03 GO:0031226 intrinsic to plasma membrane
1.67 1.05e-02 GO:0005794 Golgi apparatus
3.90 1.60e-02 GO:0031227 intrinsic to endoplasmic reticulum membrane
1.56 2.51e-02 GO:0005887 integral to plasma membrane
2.70 4.05e-02 GO:0031300 intrinsic to organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.61 1.21e-02 GO:0005215 transporter activity
1.30 1.23e-02 GO:0043167 ion binding
6.04 1.78e-02 GO:0008376 acetylgalactosaminyltransferase activity
1.29 2.26e-02 GO:0046872 metal ion binding
1.64 2.77e-02 GO:0022892 substrate-specific transporter activity
2.87 2.96e-02 GO:0046873 metal ion transmembrane transporter activity
1.28 3.14e-02 GO:0043169 cation binding
2.13 3.36e-02 GO:0022804 active transmembrane transporter activity