Motif ID: DBP.p2

Z-value: 1.030


Transcription factors associated with DBP.p2:

Gene SymbolEntrez IDGene Name
DBP 1628 D site of albumin promoter (albumin D-box) binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
DBPchr19_-_49140569-0.275.2e-01Click!


Activity profile for motif DBP.p2.

activity profile for motif DBP.p2


Sorted Z-values histogram for motif DBP.p2

Sorted Z-values for motif DBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_91576579 2.818 DCN
decorin
chr12_-_91576805 2.004 NM_001920
DCN
decorin
chr5_+_71502700 1.975 MAP1B
microtubule-associated protein 1B
chr9_-_95186559 1.891 NM_005014
OMD
osteomodulin
chr1_+_114522029 1.631 NM_020190
OLFML3
olfactomedin-like 3
chrX_-_135749436 1.532 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_+_70916158 1.524 NM_002159
HTN1
histatin 1
chr4_+_55095263 1.354 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr1_-_168698412 1.273 NM_001937
DPT
dermatopontin
chr6_-_117747017 1.262 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr2_-_190044330 1.195 NM_000393
COL5A2
collagen, type V, alpha 2
chr5_-_158526698 1.162 NM_024007
EBF1
early B-cell factor 1
chr1_+_215178884 1.160 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr6_-_46293404 1.150 RCAN2
regulator of calcineurin 2
chr3_-_114343791 1.108 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_46293628 1.084 NM_005822
RCAN2
regulator of calcineurin 2
chr3_-_112359547 0.941 CCDC80
coiled-coil domain containing 80
chr11_+_15133969 0.928 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr2_+_33359607 0.923 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr4_-_159094163 0.917 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr4_-_159093523 0.873 FAM198B
family with sequence similarity 198, member B
chr18_-_65182507 0.863 DSEL
dermatan sulfate epimerase-like
chr3_-_187452669 0.855 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr3_-_112359443 0.825 CCDC80
coiled-coil domain containing 80
chr3_-_112359660 0.818 CCDC80
coiled-coil domain containing 80
chr1_-_54199876 0.814 NM_147193
GLIS1
GLIS family zinc finger 1
chr3_-_112359565 0.802 CCDC80
coiled-coil domain containing 80
chr4_-_159093717 0.795 NM_016613
FAM198B
family with sequence similarity 198, member B
chr2_+_210444154 0.765 MAP2
microtubule-associated protein 2
chr6_+_72926462 0.762 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_183774214 0.758 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chrX_+_66788682 0.755 NM_001011645
AR
androgen receptor
chr6_+_136172802 0.707 NM_018945
PDE7B
phosphodiesterase 7B
chr12_-_91505215 0.700 LUM
lumican
chr9_-_89562103 0.691 NM_002048
GAS1
growth arrest-specific 1
chr3_+_45927995 0.671 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr2_+_210444364 0.665 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr5_-_138210992 0.646 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr13_+_93879011 0.644 NM_005708
GPC6
glypican 6
chr10_+_69869249 0.620 NM_032578
MYPN
myopalladin
chr15_+_33010174 0.618 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr18_+_72922725 0.615 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr11_+_113930430 0.610 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chrX_-_135863033 0.600 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_+_32710742 0.595 NM_001204376
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chrX_+_66763868 0.594 NM_000044
AR
androgen receptor
chr9_+_118916069 0.593 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr2_+_128175989 0.591 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chrX_-_135863104 0.590 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_+_128176019 0.589 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr5_-_158526428 0.584 EBF1
early B-cell factor 1
chr16_+_86612114 0.575 NM_005250
FOXL1
forkhead box L1
chr5_-_138211054 0.570 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr12_-_91505541 0.568 NM_002345
LUM
lumican
chr10_-_79397394 0.567 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_112359863 0.555 CCDC80
coiled-coil domain containing 80
chr15_-_90349819 0.552 ANPEP
alanyl (membrane) aminopeptidase
chr4_-_186732208 0.551 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr12_-_56236614 0.550 NM_002429
MMP19
matrix metallopeptidase 19
chr7_+_120629444 0.546 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr4_-_138453628 0.535 NM_019035
PCDH18
protocadherin 18
chr12_-_56106061 0.526 NM_001144997
ITGA7
integrin, alpha 7
chr10_-_79397290 0.524 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_31514620 0.513 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chr13_-_33760215 0.510 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr5_+_161277391 0.509 NM_001127647
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr9_-_20622476 0.505 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr17_+_41158741 0.504 NM_005533
IFI35
interferon-induced protein 35
chr6_-_31514393 0.501 ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr3_-_112359962 0.496 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr10_-_79397204 0.496 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_79397470 0.495 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_-_138453564 0.493 PCDH18
protocadherin 18
chr20_+_33134691 0.483 NM_181509
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr5_-_111091947 0.481 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr3_+_69812620 0.477 NM_001184967
MITF
microphthalmia-associated transcription factor
chr1_-_72748491 0.476


chr19_-_51845377 0.472 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr6_-_46459710 0.468 NM_001251973
RCAN2
regulator of calcineurin 2
chr2_-_163099877 0.467 NM_004460
FAP
fibroblast activation protein, alpha
chr5_-_95158365 0.464 GLRX
glutaredoxin (thioltransferase)
chr17_-_66951381 0.463 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr4_+_70894129 0.459 NM_000200
HTN3
histatin 3
chr4_-_159092509 0.458 FAM198B
family with sequence similarity 198, member B
chr4_+_114214102 0.458 ANK2
ankyrin 2, neuronal
chr1_-_182354649 0.454 GLUL
glutamate-ammonia ligase
chr1_-_72748147 0.453 NM_173808
NEGR1
neuronal growth regulator 1
chr10_-_64576123 0.449 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr3_+_69812961 0.445 NM_006722
MITF
microphthalmia-associated transcription factor
chr4_-_186732047 0.440 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr10_-_79397546 0.437 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr9_-_20622433 0.437 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr3_-_114478117 0.435 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr13_-_34250899 0.433 NM_001243476
STARD13
StAR-related lipid transfer (START) domain containing 13
chr14_-_73360792 0.432 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr5_-_95158465 0.430 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr20_+_11898536 0.430 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr3_-_114343052 0.430 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_100770378 0.428 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr3_-_100712248 0.425 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr8_-_108510094 0.422 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr5_-_149535138 0.420 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr5_-_39394423 0.419 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr4_-_100242487 0.414 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_-_112359251 0.413 CCDC80
coiled-coil domain containing 80
chr10_-_64576074 0.410 EGR2
early growth response 2
chr4_+_113970784 0.410 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr3_-_112359277 0.409 CCDC80
coiled-coil domain containing 80
chr17_-_8424217 0.405 MYH10
myosin, heavy chain 10, non-muscle
chr14_+_55168831 0.397 SAMD4A
sterile alpha motif domain containing 4A
chr1_+_159173802 0.394 NM_002036
DARC
Duffy blood group, chemokine receptor
chr15_+_72409191 0.394 NM_001172109
NM_001172110
SENP8

SUMO/sentrin specific peptidase family member 8

chr1_-_232651227 0.390 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr5_+_82767492 0.389 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr5_-_172755418 0.384 STC2
stanniocalcin 2
chr17_-_1619473 0.383 MIR22HG
MIR22 host gene (non-protein coding)
chr3_-_112358758 0.381 CCDC80
coiled-coil domain containing 80
chr1_+_65730423 0.377 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr20_-_39928708 0.374 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr5_-_124080773 0.374 NM_020747
ZNF608
zinc finger protein 608
chr11_-_102401430 0.370 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr9_+_18474078 0.367 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr12_-_46357949 0.364


chr1_+_104159953 0.363 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chrX_-_135863502 0.362 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_-_192711651 0.354 SDPR
serum deprivation response
chr10_+_83637442 0.351 NM_001165973
NRG3
neuregulin 3
chr1_+_59775749 0.348 NM_001244714
FGGY
FGGY carbohydrate kinase domain containing
chr20_-_45976626 0.341 ZMYND8
zinc finger, MYND-type containing 8
chr15_-_63449479 0.340 NM_015920
RPS27L
ribosomal protein S27-like
chr1_+_171060017 0.337 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr1_-_163113938 0.337 RGS5
regulator of G-protein signaling 5
chr6_-_35696359 0.335 NM_001145775
FKBP5
FK506 binding protein 5
chr5_+_71403040 0.332 NM_005909
MAP1B
microtubule-associated protein 1B
chr1_+_84609941 0.332 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr13_-_41593405 0.328 ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_+_113930296 0.326 ZBTB16
zinc finger and BTB domain containing 16
chr5_-_39425030 0.325 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr16_+_29823408 0.325 NM_145239
PRRT2
proline-rich transmembrane protein 2
chrX_-_19140581 0.323 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr4_+_55095433 0.323 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr9_-_73736513 0.322 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr13_+_58205943 0.321 PCDH17
protocadherin 17
chr6_-_31514313 0.319 ATP6V1G2-DDX39B
ATP6V1G2
ATP6V1G2-DDX39B readthrough (non-protein coding)
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr10_+_35484054 0.318 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr3_-_195310770 0.318 APOD
apolipoprotein D
chr4_+_15471488 0.318 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr16_-_4896197 0.314 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr10_-_31288420 0.311 NM_001143769
ZNF438
zinc finger protein 438
chr7_-_28998028 0.311 NM_014817
TRIL
TLR4 interactor with leucine-rich repeats
chr1_-_150780705 0.310 NM_000396
CTSK
cathepsin K
chr7_+_134576187 0.310 CALD1
caldesmon 1
chr5_+_67586466 0.309 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr7_+_142560512 0.303 EPHB6
EPH receptor B6
chr5_-_149535420 0.303 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr12_-_15038724 0.302 NM_000900
NM_001190839
MGP

matrix Gla protein

chr7_-_150946031 0.301 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr4_+_160188997 0.298 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_+_170662044 0.298 SSB
Sjogren syndrome antigen B (autoantigen La)
chr17_-_48262900 0.295 COL1A1
collagen, type I, alpha 1
chr10_+_17270257 0.293 NM_003380
VIM
vimentin
chr17_-_53809444 0.293 NM_001099640
TMEM100
transmembrane protein 100
chr4_-_157892466 0.293 PDGFC
platelet derived growth factor C
chrX_+_85517970 0.291 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr5_+_140602914 0.291 NM_018934
PCDHB14
protocadherin beta 14
chr7_-_150945731 0.289 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr16_+_29823557 0.288 PRRT2
proline-rich transmembrane protein 2
chr14_-_74551073 0.282 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr16_+_69680959 0.280 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr3_-_151987332 0.279 LOC401093
uncharacterized LOC401093
chr10_-_44063906 0.279 NM_005674
ZNF239
zinc finger protein 239
chr4_-_157892054 0.278 PDGFC
platelet derived growth factor C
chr1_+_51435641 0.278 NM_078626
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr18_+_3594056 0.276 FLJ35776
uncharacterized LOC649446
chr7_+_90893735 0.276 NM_003505
FZD1
frizzled family receptor 1
chr1_+_159141376 0.276 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr17_-_19651586 0.275 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr11_+_19372270 0.275 NM_001111018
NAV2
neuron navigator 2
chr5_+_140571903 0.274 NM_018930
PCDHB10
protocadherin beta 10
chr12_+_12764844 0.273 CREBL2
cAMP responsive element binding protein-like 2
chr20_-_34543280 0.272 NM_016558
SCAND1
SCAN domain containing 1
chr8_+_17822093 0.269 PCM1
pericentriolar material 1
chr5_+_140739589 0.267 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr2_-_145277879 0.266 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr1_-_241799101 0.265 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr2_+_228678556 0.265 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr17_-_4693595 0.262 LOC284014
uncharacterized LOC284014
chr6_-_167275657 0.259 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr16_+_2809933 0.256


chr13_+_76334796 0.253 NM_015842
LMO7
LIM domain 7
chr6_+_155411422 0.251 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr3_+_152017193 0.250 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr1_+_164528914 0.250 PBX1
pre-B-cell leukemia homeobox 1
chr11_-_66445318 0.248 RBM4B
RNA binding motif protein 4B
chr11_-_66445218 0.244 NM_031492
RBM4B
RNA binding motif protein 4B
chr20_+_31595513 0.243 BPIFB2
BPI fold containing family B, member 2
chr2_-_224467142 0.242 NM_003469
SCG2
secretogranin II
chr5_+_140710203 0.241 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr5_-_111312522 0.236 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr4_-_175443601 0.236 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 2.38e-04 GO:0023051 regulation of signaling
1.43 4.33e-04 GO:0009966 regulation of signal transduction
1.09 6.29e-04 GO:0009987 cellular process
1.15 7.94e-04 GO:0050794 regulation of cellular process
2.48 1.98e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.30 2.04e-03 GO:0048519 negative regulation of biological process
1.14 2.29e-03 GO:0050789 regulation of biological process
1.13 2.64e-03 GO:0065007 biological regulation
1.31 3.99e-03 GO:0048523 negative regulation of cellular process
1.26 6.62e-03 GO:0048731 system development
1.24 7.40e-03 GO:0048856 anatomical structure development
1.32 9.75e-03 GO:0048583 regulation of response to stimulus
1.36 1.24e-02 GO:0007399 nervous system development
1.20 2.29e-02 GO:0032502 developmental process
1.21 3.31e-02 GO:0007275 multicellular organismal development
2.67 3.99e-02 GO:0030178 negative regulation of Wnt receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 2.41e-04 GO:0005829 cytosol
2.45 1.26e-03 GO:0030016 myofibril
2.38 1.55e-03 GO:0043292 contractile fiber
2.43 2.16e-03 GO:0044449 contractile fiber part
2.51 3.46e-03 GO:0030017 sarcomere
1.07 4.44e-03 GO:0005622 intracellular
1.11 5.96e-03 GO:0005737 cytoplasm
2.81 1.04e-02 GO:0030426 growth cone
2.72 1.68e-02 GO:0030427 site of polarized growth

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 6.69e-07 GO:0005515 protein binding
1.07 5.00e-03 GO:0005488 binding
1.79 4.60e-02 GO:0005096 GTPase activator activity