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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: EGR1..3.p2

Z-value: 3.179

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_16964730	7.119	NM_001080975 NM_004726	REPS2	RALBP1 associated Eps domain containing 2
chr6_-_46459010	5.752	NM_001251974	RCAN2	regulator of calcineurin 2
chr2_+_109745996	5.053	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr1_-_38471170	3.370	NM_001243878 NM_004468	FHL3	four and a half LIM domains 3
chr5_-_9546157	3.285	NM_003966	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr8_+_16884745	3.200	NM_181723	EFHA2	EF-hand domain family, member A2
chr8_+_72756335	3.109
chr2_-_99552677	2.982	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr12_-_124457099	2.914	NM_025140	CCDC92	coiled-coil domain containing 92
chr8_+_72756218	2.846		LOC100132891	uncharacterized LOC100132891
chr2_+_23608297	2.693	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr3_+_12329332	2.684	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr6_+_84743250	2.537	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2
chr5_-_168727715	2.504	NM_003062	SLIT3	slit homolog 3 (Drosophila)
chr1_+_159141376	2.500	NM_021189 NM_001127173	CADM3	cell adhesion molecule 3
chr7_+_94023872	2.353	NM_000089	COL1A2	collagen, type I, alpha 2
chr1_+_78354199	2.296	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr6_-_74363689	2.202	NM_012434	SLC17A5	solute carrier family 17 (anion/sugar transporter), member 5
chr10_+_131265453	2.020	NM_002412	MGMT	O-6-methylguanine-DNA methyltransferase
chr21_+_47545896	2.003		COL6A2	collagen, type VI, alpha 2
chr10_+_131265500	1.983		MGMT	O-6-methylguanine-DNA methyltransferase
chr8_+_17354562	1.950	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr5_-_10761341	1.948		DAP	death-associated protein
chr2_-_230135954	1.941	NM_001100818 NM_017933	PID1	phosphotyrosine interaction domain containing 1
chr19_+_47778099	1.930	NM_178511	PRR24	proline rich 24
chr10_-_79397290	1.917		KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_-_76921076	1.912		TIMP2	TIMP metallopeptidase inhibitor 2
chr11_+_124609775	1.901	NM_001126181 NM_006176	NRGN	neurogranin (protein kinase C substrate, RC3)
chr5_-_10761344	1.870	NM_004394	DAP	death-associated protein
chr20_+_34894190	1.827		DLGAP4	discs, large (Drosophila) homolog-associated protein 4
chr12_+_57482886	1.823		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr3_+_20081853	1.803		KAT2B	K(lysine) acetyltransferase 2B
chr1_+_215256559	1.796	NM_001017425 NM_014217	KCNK2	potassium channel, subfamily K, member 2
chr7_-_150945731	1.791	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_+_172068188	1.781	NM_001142651	NEURL1B	neuralized homolog 1B (Drosophila)
chr19_-_18392436	1.771		JUND	jun D proto-oncogene
chr5_-_10761179	1.769		DAP	death-associated protein
chr9_+_90112419	1.744		DAPK1	death-associated protein kinase 1
chr19_+_16435734	1.736		KLF2	Kruppel-like factor 2 (lung)
chr19_+_2476122	1.699	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr20_-_48099178	1.699	NM_004975	KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1
chr12_+_90103470	1.698		LOC338758	uncharacterized LOC338758
chr4_+_129732427	1.697		PHF17	PHD finger protein 17
chr19_+_56159400	1.695		CCDC106	coiled-coil domain containing 106
chr6_+_124125068	1.681	NM_001040214 NM_153355	NKAIN2	Na+/K+ transporting ATPase interacting 2
chr3_+_32280211	1.635		CMTM8	CKLF-like MARVEL transmembrane domain containing 8
chr11_+_124609841	1.623		NRGN	neurogranin (protein kinase C substrate, RC3)
chr5_-_81046943	1.592	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr5_+_92920592	1.589		NR2F1 NR2F2	nuclear receptor subfamily 2, group F, member 1 nuclear receptor subfamily 2, group F, member 2
chr12_+_90102639	1.555		LOC338758	uncharacterized LOC338758
chr14_+_105941061	1.551	NM_001312	CRIP2	cysteine-rich protein 2
chr12_-_56101667	1.550	NM_001144996 NM_002206	ITGA7	integrin, alpha 7
chrX_+_9432980	1.531	NM_005647	TBL1X	transducin (beta)-like 1X-linked
chr8_-_72756384	1.529		MSC	musculin
chr8_+_104383785	1.504	NM_138455	CTHRC1	collagen triple helix repeat containing 1
chr8_+_104383701	1.500		CTHRC1	collagen triple helix repeat containing 1
chr7_+_90225607	1.490		CDK14	cyclin-dependent kinase 14
chr17_-_79008372	1.461		FLJ90757	uncharacterized LOC440465
chr5_+_133861685	1.461	NM_015288	PHF15	PHD finger protein 15
chr8_-_72756607	1.449		MSC	musculin
chr7_+_35840595	1.427	NM_001011553 NM_001242956 NM_001788	SEPT7	septin 7
chr7_+_73082320	1.421		VPS37D	vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr1_+_65991390	1.418		LEPR	leptin receptor
chr20_+_34742656	1.414	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr5_-_172755418	1.412		STC2	stanniocalcin 2
chr5_+_40680042	1.402		PTGER4	prostaglandin E receptor 4 (subtype EP4)
chr19_-_3028901	1.400	NM_003260	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr17_-_74236272	1.395	NM_052916	RNF157	ring finger protein 157
chr9_+_123963728	1.384		GSN	gelsolin
chr3_+_11196213	1.367	NM_001098212	HRH1	histamine receptor H1
chr1_+_65991357	1.357	NM_001198687 NM_001198688 NM_001198689	LEPR	leptin receptor
chr19_+_35759967	1.342		USF2	upstream transcription factor 2, c-fos interacting
chr6_+_72596699	1.341		RIMS1	regulating synaptic membrane exocytosis 1
chr9_+_35829208	1.338	NM_016446 NM_001042589	TMEM8B	transmembrane protein 8B
chr9_-_86432546	1.331	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr7_-_28220146	1.323		JAZF1	JAZF zinc finger 1
chrX_+_66763868	1.323	NM_000044	AR	androgen receptor
chr6_-_85473898	1.320	NM_001080508	TBX18	T-box 18
chr15_-_93632161	1.305	NM_020211	RGMA	RGM domain family, member A
chr19_-_40791145	1.300		AKT2	v-akt murine thymoma viral oncogene homolog 2
chr2_-_25896282	1.293	NM_021907 NM_033147 NM_033148 NM_183360 NM_183361	DTNB	dystrobrevin, beta
chr19_+_41107220	1.289	NM_001042545	LTBP4	latent transforming growth factor beta binding protein 4
chr6_+_79787548	1.283		PHIP	pleckstrin homology domain interacting protein
chr7_-_28220342	1.271	NM_175061	JAZF1	JAZF zinc finger 1
chr16_-_54962707	1.258		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr2_+_241938254	1.257	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr12_-_109251333	1.257	NM_001161330 NM_018984	SSH1	slingshot homolog 1 (Drosophila)
chr1_+_150122415	1.255		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr8_+_17014006	1.255		ZDHHC2	zinc finger, DHHC-type containing 2
chr20_+_61569358	1.254	NM_017896	C20orf11	chromosome 20 open reading frame 11
chr15_+_33010174	1.254	NM_001191322 NM_001191323 NM_013372	GREM1	gremlin 1
chr14_-_23821423	1.252	NM_020372	SLC22A17	solute carrier family 22, member 17
chr5_-_137089434	1.251		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr6_+_72596648	1.251	NM_014989	RIMS1	regulating synaptic membrane exocytosis 1
chr1_+_226250413	1.249		H3F3A	H3 histone, family 3A
chr9_-_130661781	1.246		ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr5_+_172483285	1.234	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr19_+_14544216	1.230		PKN1	protein kinase N1
chr9_-_130661886	1.222		ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_+_150122246	1.220		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr19_-_18392413	1.219	NM_005354	JUND	jun D proto-oncogene
chr5_-_81046858	1.215		SSBP2	single-stranded DNA binding protein 2
chr5_-_176924601	1.209	NM_005451 NM_203352 NM_213636	PDLIM7	PDZ and LIM domain 7 (enigma)
chr10_-_79397204	1.205		KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_-_46115135	1.197	NM_016429	COPZ2	coatomer protein complex, subunit zeta 2
chr1_-_33647626	1.196	NM_018207	TRIM62	tripartite motif containing 62
chr19_+_52800424	1.194	NM_144684	ZNF480	zinc finger protein 480
chr13_+_98086681	1.188		RAP2A	RAP2A, member of RAS oncogene family
chr4_-_119273874	1.185	NM_003619	PRSS12	protease, serine, 12 (neurotrypsin, motopsin)
chr6_+_72596405	1.182		RIMS1	regulating synaptic membrane exocytosis 1
chr4_+_134073180	1.175		PCDH10	protocadherin 10
chr19_+_16435632	1.156	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr3_-_183979074	1.149	NM_033259	CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chrX_-_152939256	1.127		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr2_-_225907312	1.126	NM_014689	DOCK10	dedicator of cytokinesis 10
chr9_-_130661823	1.114	NM_013443	ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr14_-_53417808	1.113	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr20_+_36531548	1.110		VSTM2L	V-set and transmembrane domain containing 2 like
chr19_-_40791224	1.097		AKT2	v-akt murine thymoma viral oncogene homolog 2
chr5_-_172755195	1.093		STC2	stanniocalcin 2
chr20_+_36531498	1.090	NM_080607	VSTM2L	V-set and transmembrane domain containing 2 like
chr8_-_72756687	1.086	NM_005098	MSC	musculin
chr16_+_29817810	1.083	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_-_150946031	1.078		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr7_+_33168851	1.071	NM_001033604 NM_001033605 NM_014451 NM_198428	BBS9	Bardet-Biedl syndrome 9
chr8_-_38325524	1.066		FGFR1	fibroblast growth factor receptor 1
chr1_-_3528058	1.061	NM_001409	MEGF6	multiple EGF-like-domains 6
chrX_-_19140581	1.060	NM_001079858 NM_001079859 NM_001079860 NM_001184833 NM_001184834 NM_001184835 NM_001184836 NM_001184837 NM_005756	GPR64	G protein-coupled receptor 64
chr1_-_85930733	1.054	NM_012137	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr2_+_56411123	1.052	NM_001080433	CCDC85A	coiled-coil domain containing 85A
chr12_+_79258794	1.051		SYT1	synaptotagmin I
chr17_+_81037504	1.049	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr5_-_176924552	1.047		PDLIM7	PDZ and LIM domain 7 (enigma)
chr10_+_12391708	1.046		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr9_-_130661874	1.046		ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr19_-_40791248	1.045		AKT2	v-akt murine thymoma viral oncogene homolog 2
chr11_-_695402	1.044	NM_021008	DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr1_+_77747602	1.044	NM_174858	AK5	adenylate kinase 5
chr5_+_40680021	1.034	NM_000958	PTGER4	prostaglandin E receptor 4 (subtype EP4)
chr2_-_202316227	1.030	NM_015049	TRAK2	trafficking protein, kinesin binding 2
chr19_+_14544100	1.028	NM_002741	PKN1	protein kinase N1
chr14_-_53417636	1.027		FERMT2	fermitin family member 2
chr3_+_73046081	1.027	NM_174907	PPP4R2	protein phosphatase 4, regulatory subunit 2
chr12_+_12764844	1.015		CREBL2	cAMP responsive element binding protein-like 2
chr5_+_137774897	1.014		REEP2	receptor accessory protein 2
chr13_+_76210449	1.013		LMO7	LIM domain 7
chr19_+_44037287	1.013	NM_174945	ZNF575	zinc finger protein 575
chr11_+_64001974	1.011	NM_001243733 NM_003377	VEGFB	vascular endothelial growth factor B
chr12_+_6875686	1.001		PTMS	parathymosin
chr11_+_289113	0.997	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr10_+_93170086	0.985	NM_173497 NM_182765	HECTD2	HECT domain containing 2
chr14_-_53258329	0.983	NM_198066	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1
chr17_+_65822206	0.981		BPTF	bromodomain PHD finger transcription factor
chr2_+_48757292	0.980	NM_001198595 NM_006873	STON1	stonin 1
chr14_+_75894508	0.979	NM_001135047	JDP2	Jun dimerization protein 2
chr1_-_51425795	0.977		FAF1	Fas (TNFRSF6) associated factor 1
chr5_+_149569810	0.972		SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr2_-_180129245	0.972	NM_178123	SESTD1	SEC14 and spectrin domains 1
chr4_-_57976355	0.971		IGFBP7	insulin-like growth factor binding protein 7
chrX_+_9754465	0.967	NM_001649	SHROOM2	shroom family member 2
chr8_-_38325241	0.956	NM_001174065 NM_001174066 NM_001174067	FGFR1	fibroblast growth factor receptor 1
chr19_+_18530423	0.945
chr1_-_51425918	0.943	NM_007051	FAF1	Fas (TNFRSF6) associated factor 1
chr1_-_51425740	0.942		FAF1	Fas (TNFRSF6) associated factor 1
chr22_-_31503484	0.938	NM_080430	SELM	selenoprotein M
chr20_+_45338125	0.938	NM_030777	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10
chr9_-_95896498	0.936	NM_004148	NINJ1	ninjurin 1
chr12_+_57482674	0.932	NM_005967	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr16_-_73092533	0.932	NM_001164766	ZFHX3	zinc finger homeobox 3
chr1_-_15850776	0.929	NM_001229 NM_032996	CASP9	caspase 9, apoptosis-related cysteine peptidase
chr1_+_43148359	0.925		YBX1	Y box binding protein 1
chr6_+_108882104	0.923		FOXO3	forkhead box O3
chrX_-_15872938	0.921		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr7_+_94024201	0.921		COL1A2	collagen, type I, alpha 2
chr2_-_219432955	0.917	NM_020935	USP37	ubiquitin specific peptidase 37
chr15_-_82338459	0.914		MEX3B	mex-3 homolog B (C. elegans)
chr10_+_60272868	0.910	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr19_-_12845539	0.907		C19orf43	chromosome 19 open reading frame 43
chr17_-_1083008	0.906	NM_021962	ABR	active BCR-related gene
chr12_+_6875468	0.906	NM_002824	PTMS	parathymosin
chr7_+_100199881	0.901	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr21_-_35987144	0.900	NM_004414	RCAN1	regulator of calcineurin 1
chr1_+_236305831	0.898	NM_003272	GPR137B	G protein-coupled receptor 137B
chr12_+_104458235	0.892	NM_013320	HCFC2	host cell factor C2
chr12_-_29936685	0.890	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr17_-_79791026	0.886		FAM195B	family with sequence similarity 195, member B
chr3_-_15900928	0.886	NM_015199	ANKRD28	ankyrin repeat domain 28
chr2_+_200323088	0.883
chr10_-_21805715	0.879		C10orf140	chromosome 10 open reading frame 140
chr16_+_69600110	0.870		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr6_-_35656677	0.869	NM_001145776 NM_001145777 NM_004117	FKBP5	FK506 binding protein 5
chr17_-_42296923	0.869		UBTF	upstream binding transcription factor, RNA polymerase I
chr12_+_57482922	0.868		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr9_-_15510899	0.865	NM_001128217 NM_033222	PSIP1	PC4 and SFRS1 interacting protein 1
chr15_+_76135992	0.862		UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2
chr17_-_62914902	0.860	NM_199340	LRRC37A3	leucine rich repeat containing 37, member A3
chr8_-_60031545	0.860	NM_014729	TOX	thymocyte selection-associated high mobility group box
chr17_-_5404304	0.858	NM_001162371	LOC728392	uncharacterized LOC728392
chr10_-_81205091	0.858	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr8_-_74659082	0.857	NM_001164380 NM_001164381 NM_001164382 NM_001164383 NM_001164385 NM_014393	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.17	2.36e-14	GO:0050794	regulation of cellular process
1.16	1.58e-12	GO:0050789	regulation of biological process
1.45	1.73e-12	GO:0007399	nervous system development
1.57	8.19e-12	GO:0022008	neurogenesis
1.26	4.71e-11	GO:0060255	regulation of macromolecule metabolic process
1.57	5.94e-11	GO:0048699	generation of neurons
1.25	8.40e-11	GO:0031323	regulation of cellular metabolic process
1.14	1.18e-10	GO:0065007	biological regulation
1.23	1.71e-10	GO:0019222	regulation of metabolic process
1.16	3.14e-10	GO:0044237	cellular metabolic process
1.09	3.65e-10	GO:0009987	cellular process
1.24	3.90e-10	GO:0080090	regulation of primary metabolic process
1.50	9.56e-10	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.32	1.28e-09	GO:0048523	negative regulation of cellular process
1.84	1.46e-09	GO:0016568	chromatin modification
1.76	2.00e-09	GO:0048667	cell morphogenesis involved in neuron differentiation
1.24	2.28e-09	GO:0016043	cellular component organization
1.29	2.58e-09	GO:0010468	regulation of gene expression
1.74	4.12e-09	GO:0048812	neuron projection morphogenesis
1.30	4.48e-09	GO:0051252	regulation of RNA metabolic process
1.30	5.07e-09	GO:0048519	negative regulation of biological process
1.76	5.23e-09	GO:0007409	axonogenesis
1.69	6.59e-09	GO:0000904	cell morphogenesis involved in differentiation
1.30	1.31e-08	GO:0006355	regulation of transcription, DNA-dependent
1.27	1.94e-08	GO:0071842	cellular component organization at cellular level
1.68	2.28e-08	GO:0031175	neuron projection development
1.66	5.13e-08	GO:0048858	cell projection morphogenesis
1.28	7.21e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.65	1.08e-07	GO:0032990	cell part morphogenesis
1.80	1.11e-07	GO:0070647	protein modification by small protein conjugation or removal
1.22	1.15e-07	GO:0071840	cellular component organization or biogenesis
1.26	1.40e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19	1.50e-07	GO:0044260	cellular macromolecule metabolic process
1.22	1.80e-07	GO:0007275	multicellular organismal development
1.20	2.09e-07	GO:0032502	developmental process
1.58	2.10e-07	GO:0010629	negative regulation of gene expression
1.61	2.32e-07	GO:0051253	negative regulation of RNA metabolic process
1.25	2.82e-07	GO:0009889	regulation of biosynthetic process
1.26	3.08e-07	GO:0010556	regulation of macromolecule biosynthetic process
1.25	3.97e-07	GO:0031326	regulation of cellular biosynthetic process
1.50	5.22e-07	GO:0016192	vesicle-mediated transport
1.57	5.40e-07	GO:0000902	cell morphogenesis
1.31	6.58e-07	GO:0006464	protein modification process
1.84	6.78e-07	GO:0032446	protein modification by small protein conjugation
1.64	8.26e-07	GO:0006325	chromatin organization
1.24	8.38e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.59	1.16e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.54	1.27e-06	GO:0030030	cell projection organization
1.56	1.81e-06	GO:0048666	neuron development
1.24	1.89e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.25	1.94e-06	GO:0048522	positive regulation of cellular process
1.12	2.53e-06	GO:0008152	metabolic process
1.33	2.87e-06	GO:0009653	anatomical structure morphogenesis
1.32	3.05e-06	GO:0023051	regulation of signaling
1.52	4.19e-06	GO:0032989	cellular component morphogenesis
1.28	4.85e-06	GO:0043412	macromolecule modification
2.00	5.46e-06	GO:0016569	covalent chromatin modification
1.42	6.40e-06	GO:0048468	cell development
1.49	7.20e-06	GO:0009890	negative regulation of biosynthetic process
1.37	8.05e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.81	8.89e-06	GO:0016567	protein ubiquitination
1.48	1.26e-05	GO:0030182	neuron differentiation
1.71	1.26e-05	GO:0007411	axon guidance
1.22	1.49e-05	GO:0048731	system development
1.20	1.53e-05	GO:0048856	anatomical structure development
1.13	1.60e-05	GO:0044238	primary metabolic process
1.97	1.67e-05	GO:0016570	histone modification
1.22	1.92e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48	1.95e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.36	1.99e-05	GO:0031325	positive regulation of cellular metabolic process
1.41	2.00e-05	GO:0050793	regulation of developmental process
1.34	2.55e-05	GO:0051641	cellular localization
1.34	2.71e-05	GO:0009893	positive regulation of metabolic process
1.50	2.80e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39	2.88e-05	GO:0009892	negative regulation of metabolic process
1.26	3.06e-05	GO:0030154	cell differentiation
1.48	3.09e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
1.40	3.25e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.15	3.30e-05	GO:0043170	macromolecule metabolic process
1.35	4.11e-05	GO:0044248	cellular catabolic process
1.49	4.25e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.49	4.27e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.71	4.39e-05	GO:0032870	cellular response to hormone stimulus
1.44	5.31e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	6.93e-05	GO:0048869	cellular developmental process
1.40	6.94e-05	GO:0006351	transcription, DNA-dependent
1.42	9.19e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.28	1.01e-04	GO:0006996	organelle organization
1.46	1.02e-04	GO:0051254	positive regulation of RNA metabolic process
1.65	1.40e-04	GO:0071495	cellular response to endogenous stimulus
1.38	1.99e-04	GO:0031324	negative regulation of cellular metabolic process
1.59	2.05e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.41	2.11e-04	GO:0046907	intracellular transport
1.45	2.21e-04	GO:0010628	positive regulation of gene expression
1.34	2.42e-04	GO:0051649	establishment of localization in cell
1.20	3.71e-04	GO:0048518	positive regulation of biological process
1.21	3.79e-04	GO:0044267	cellular protein metabolic process
1.45	4.92e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.58	5.26e-04	GO:0007264	small GTPase mediated signal transduction
1.29	5.30e-04	GO:0009966	regulation of signal transduction
1.18	5.48e-04	GO:0034641	cellular nitrogen compound metabolic process
1.30	5.53e-04	GO:0035556	intracellular signal transduction
1.92	7.33e-04	GO:0046039	GTP metabolic process
1.35	7.78e-04	GO:0032774	RNA biosynthetic process
1.75	8.17e-04	GO:0071375	cellular response to peptide hormone stimulus
1.94	1.08e-03	GO:0006184	GTP catabolic process
1.62	1.42e-03	GO:0060284	regulation of cell development
1.37	2.05e-03	GO:0051128	regulation of cellular component organization
2.27	2.33e-03	GO:0000209	protein polyubiquitination
1.17	2.51e-03	GO:0006807	nitrogen compound metabolic process
1.68	2.86e-03	GO:0030036	actin cytoskeleton organization
1.71	3.15e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.38	3.32e-03	GO:2000026	regulation of multicellular organismal development
1.41	3.77e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.60	4.34e-03	GO:0022603	regulation of anatomical structure morphogenesis
1.31	4.55e-03	GO:0010646	regulation of cell communication
1.26	6.11e-03	GO:0009056	catabolic process
2.97	9.03e-03	GO:0070936	protein K48-linked ubiquitination
1.44	1.01e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.38	1.06e-02	GO:0045595	regulation of cell differentiation
1.45	1.08e-02	GO:0007010	cytoskeleton organization
1.30	1.08e-02	GO:0008104	protein localization
1.33	1.40e-02	GO:0045184	establishment of protein localization
1.34	1.40e-02	GO:0031328	positive regulation of cellular biosynthetic process
2.13	1.46e-02	GO:0018205	peptidyl-lysine modification
1.39	1.60e-02	GO:0051276	chromosome organization
1.33	2.12e-02	GO:0009891	positive regulation of biosynthetic process
1.16	2.32e-02	GO:0019538	protein metabolic process
1.35	2.45e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.26	2.55e-02	GO:0051239	regulation of multicellular organismal process
1.14	2.74e-02	GO:0023052	signaling
1.97	2.95e-02	GO:0040029	regulation of gene expression, epigenetic
1.72	3.11e-02	GO:0032869	cellular response to insulin stimulus
1.44	3.18e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.51	4.68e-02	GO:0043434	response to peptide hormone stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	5.16e-50	GO:0005622	intracellular
1.17	3.40e-49	GO:0044424	intracellular part
1.18	2.53e-33	GO:0043226	organelle
1.18	3.85e-33	GO:0043229	intracellular organelle
1.18	4.61e-28	GO:0043227	membrane-bounded organelle
1.27	7.29e-28	GO:0005634	nucleus
1.18	7.81e-28	GO:0043231	intracellular membrane-bounded organelle
1.19	6.99e-27	GO:0005737	cytoplasm
1.18	6.98e-13	GO:0044444	cytoplasmic part
1.33	5.76e-11	GO:0005829	cytosol
1.37	5.93e-08	GO:0005654	nucleoplasm
1.30	6.77e-08	GO:0031981	nuclear lumen
1.28	6.78e-08	GO:0044428	nuclear part
1.21	9.50e-07	GO:0043234	protein complex
1.96	1.18e-06	GO:0031252	cell leading edge
1.14	5.63e-06	GO:0044446	intracellular organelle part
1.13	6.68e-06	GO:0044422	organelle part
1.24	7.48e-06	GO:0070013	intracellular organelle lumen
1.23	7.70e-06	GO:0031974	membrane-enclosed lumen
1.59	9.53e-06	GO:0045202	synapse
1.23	1.14e-05	GO:0043233	organelle lumen
1.18	1.71e-05	GO:0032991	macromolecular complex
1.03	5.93e-05	GO:0044464	cell part
1.03	6.29e-05	GO:0005623	cell
1.37	9.09e-05	GO:0042995	cell projection
2.18	1.63e-04	GO:0016585	chromatin remodeling complex
1.39	3.24e-04	GO:0044451	nucleoplasm part
1.19	3.31e-04	GO:0043228	non-membrane-bounded organelle
1.19	3.31e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.81	6.50e-04	GO:0030136	clathrin-coated vesicle
1.71	1.25e-03	GO:0030135	coated vesicle
1.49	1.91e-03	GO:0043005	neuron projection
1.56	2.84e-03	GO:0015629	actin cytoskeleton
2.05	3.54e-03	GO:0008021	synaptic vesicle
1.55	3.89e-03	GO:0044456	synapse part
2.06	3.95e-03	GO:0030027	lamellipodium
2.38	4.05e-03	GO:0035770	RNA granule
1.38	4.15e-03	GO:0030054	cell junction
1.32	6.69e-03	GO:0031982	vesicle
1.22	7.55e-03	GO:0005856	cytoskeleton
2.04	9.27e-03	GO:0009898	internal side of plasma membrane
2.54	1.01e-02	GO:0000118	histone deacetylase complex
1.91	1.05e-02	GO:0019898	extrinsic to membrane
1.31	1.17e-02	GO:0031410	cytoplasmic vesicle
1.31	1.76e-02	GO:0031988	membrane-bounded vesicle
1.32	2.45e-02	GO:0015630	microtubule cytoskeleton
1.31	2.57e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
3.13	3.56e-02	GO:0031519	PcG protein complex
2.64	3.85e-02	GO:0000932	cytoplasmic mRNA processing body
1.85	3.90e-02	GO:0019717	synaptosome
2.55	4.06e-02	GO:0042641	actomyosin

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	2.07e-29	GO:0005515	protein binding
1.11	4.76e-24	GO:0005488	binding
1.47	1.10e-09	GO:0030528	transcription regulator activity
1.29	4.25e-08	GO:0008270	zinc ion binding
1.40	1.75e-06	GO:0001071	nucleic acid binding transcription factor activity
1.40	1.75e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.73	4.14e-06	GO:0008134	transcription factor binding
1.22	2.95e-05	GO:0046914	transition metal ion binding
1.42	3.29e-05	GO:0019899	enzyme binding
1.76	3.80e-05	GO:0019787	small conjugating protein ligase activity
1.71	5.13e-05	GO:0016881	acid-amino acid ligase activity
1.64	1.74e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.81	1.82e-04	GO:0003682	chromatin binding
1.56	2.16e-04	GO:0000988	protein binding transcription factor activity
1.56	2.16e-04	GO:0000989	transcription factor binding transcription factor activity
1.17	2.28e-04	GO:0003676	nucleic acid binding
1.41	2.77e-04	GO:0043565	sequence-specific DNA binding
1.55	3.44e-04	GO:0003712	transcription cofactor activity
1.50	5.54e-04	GO:0019904	protein domain specific binding
1.71	5.86e-04	GO:0004842	ubiquitin-protein ligase activity
1.58	9.90e-04	GO:0016564	transcription repressor activity
1.20	9.91e-04	GO:0003677	DNA binding
1.14	9.95e-04	GO:0046872	metal ion binding
1.84	1.68e-03	GO:0003714	transcription corepressor activity
1.14	1.81e-03	GO:0043169	cation binding
1.42	2.11e-03	GO:0008092	cytoskeletal protein binding
1.14	2.21e-03	GO:0043167	ion binding
1.71	2.36e-03	GO:0010843	promoter binding
1.67	5.47e-03	GO:0000975	regulatory region DNA binding
1.67	5.47e-03	GO:0001067	regulatory region nucleic acid binding
1.67	5.47e-03	GO:0044212	transcription regulatory region DNA binding
1.90	4.98e-02	GO:0019887	protein kinase regulator activity