Motif ID: ELF1,2,4.p2

Z-value: 1.292


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_41556188-0.696.0e-02Click!
ELF2chr4_-_140060601-0.403.3e-01Click!
ELF4chrX_-_129244471,
chrX_-_129244652		-0.147.4e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_+_43823970 0.386 NM_001001895
NM_001243467
NM_018961
 UBASH3A


ubiquitin associated and SH3 domain containing A


chr1_-_52870058 0.341 NM_001190818
NM_001190819
NM_004153
 ORC1


origin recognition complex, subunit 1


chr5_+_140044383 0.338 NM_017706
 WDR55
WD repeat domain 55
chr14_+_29236882 0.335 FOXG1
forkhead box G1
chr5_+_140044457 0.320 WDR55
WD repeat domain 55
chr2_-_54198055 0.317


chr22_-_19512859 0.302 NM_001130861
NM_003277
 CLDN5

claudin 5

chr2_+_65454828 0.302 NM_001005386
NM_005722
 ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr12_-_124068864 0.300


chr11_-_62389571 0.293 NM_012200
 B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr11_-_62389376 0.263 B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr16_-_89349696 0.262 ANKRD11
ankyrin repeat domain 11
chr19_-_56632644 0.252 NM_001002836
 ZNF787
zinc finger protein 787
chr10_+_26986557 0.246 NM_014317
 PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr12_+_133287382 0.235 NM_001170543
NM_001170544
NM_138575
 PGAM5


phosphoglycerate mutase family member 5


chr6_-_11382501 0.233 NM_001142393
 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr17_-_42264075 0.231 NM_178542
 C17orf65
chromosome 17 open reading frame 65
chr15_-_50647349 0.227 GABPB1
GA binding protein transcription factor, beta subunit 1
chr20_-_34287043 0.223 NM_001198989
NM_021100
 NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr5_+_892950 0.222 NM_001166260
NM_004237
 TRIP13

thyroid hormone receptor interactor 13


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 221 entries
enrichment   p-value GO term description
2.43 1.69e-02 GO:0000080 G1 phase of mitotic cell cycle
2.42 1.61e-03 GO:0006369 termination of RNA polymerase II transcription
2.34 2.78e-02 GO:0051318 G1 phase
2.23 7.38e-03 GO:0050434 positive regulation of viral transcription
2.22 8.17e-06 GO:0000216 M/G1 transition of mitotic cell cycle
2.22 1.29e-04 GO:0006405 RNA export from nucleus
2.21 5.21e-07 GO:0006352 transcription initiation, DNA-dependent
2.19 2.29e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.17 6.43e-04 GO:0006367 transcription initiation from RNA polymerase II promoter
2.17 2.28e-03 GO:0006406 mRNA export from nucleus
2.16 2.00e-05 GO:0051168 nuclear export
2.16 2.00e-05 GO:0051351 positive regulation of ligase activity
2.16 2.54e-05 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.15 7.04e-05 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.15 3.15e-04 GO:0051352 negative regulation of ligase activity
2.15 3.15e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.14 4.36e-05 GO:0022618 ribonucleoprotein complex assembly
2.13 1.95e-04 GO:0006353 transcription termination, DNA-dependent
2.13 3.92e-03 GO:0006368 transcription elongation from RNA polymerase II promoter
2.12 1.89e-07 GO:0051320 S phase

Gene overrepresentation in compartment category:

Showing 1 to 20 of 64 entries
enrichment   p-value GO term description
2.94 2.62e-04 GO:0005689 U12-type spliceosomal complex
2.79 3.32e-05 GO:0030532 small nuclear ribonucleoprotein complex
2.30 2.95e-14 GO:0005681 spliceosomal complex
2.28 1.38e-07 GO:0071013 catalytic step 2 spliceosome
2.09 1.44e-04 GO:0000777 condensed chromosome kinetochore
2.09 8.28e-04 GO:0000502 proteasome complex
2.06 3.24e-05 GO:0030027 lamellipodium
2.05 1.44e-04 GO:0000779 condensed chromosome, centromeric region
2.03 2.83e-03 GO:0044450 microtubule organizing center part
2.01 6.49e-05 GO:0000776 kinetochore
1.96 4.18e-03 GO:0005643 nuclear pore
1.95 1.71e-07 GO:0000793 condensed chromosome
1.94 3.16e-04 GO:0001726 ruffle
1.94 1.08e-02 GO:0000922 spindle pole
1.91 5.92e-07 GO:0000775 chromosome, centromeric region
1.90 2.03e-03 GO:0046930 pore complex
1.86 9.70e-03 GO:0031461 cullin-RING ubiquitin ligase complex
1.84 1.14e-05 GO:0000151 ubiquitin ligase complex
1.83 1.09e-02 GO:0000790 nuclear chromatin
1.81 4.77e-07 GO:0031252 cell leading edge

Gene overrepresentation in function category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
2.14 2.76e-02 GO:0004812 aminoacyl-tRNA ligase activity
2.14 2.76e-02 GO:0016875 ligase activity, forming carbon-oxygen bonds
2.14 2.76e-02 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
1.90 4.38e-03 GO:0008135 translation factor activity, nucleic acid binding
1.84 1.04e-03 GO:0008026 ATP-dependent helicase activity
1.84 1.04e-03 GO:0070035 purine NTP-dependent helicase activity
1.81 6.54e-05 GO:0004386 helicase activity
1.61 2.63e-20 GO:0003723 RNA binding
1.56 1.69e-03 GO:0004842 ubiquitin-protein ligase activity
1.53 6.56e-03 GO:0003713 transcription coactivator activity
1.52 4.17e-03 GO:0019787 small conjugating protein ligase activity
1.43 4.85e-02 GO:0016881 acid-amino acid ligase activity
1.41 3.21e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.40 5.84e-03 GO:0000988 protein binding transcription factor activity
1.40 5.84e-03 GO:0000989 transcription factor binding transcription factor activity
1.40 2.75e-02 GO:0016563 transcription activator activity
1.39 1.05e-03 GO:0016874 ligase activity
1.39 8.32e-03 GO:0003712 transcription cofactor activity
1.36 1.50e-02 GO:0004674 protein serine/threonine kinase activity
1.33 1.10e-04 GO:0019899 enzyme binding