Motif ID: ESRRA.p2

Z-value: 0.876


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
ESRRA 2101 estrogen-related receptor alpha

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESRRAchr11_+_640730400.696.0e-02Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_35629727 0.747 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr20_+_58179601 0.721 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr15_-_81616439 0.636 NM_181900
STARD5
StAR-related lipid transfer (START) domain containing 5
chr15_-_83621350 0.596 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr15_+_43885251 0.555 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr16_-_4588379 0.504 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr15_+_43985083 0.478 NM_001015001
CKMT1A
creatine kinase, mitochondrial 1A
chr3_-_121379701 0.469 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_29213619 0.466 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr6_-_34360310 0.441 NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr15_+_59730272 0.422 NM_152450
FAM81A
family with sequence similarity 81, member A
chr14_-_103989112 0.410 CKB
creatine kinase, brain
chr6_-_43027114 0.406 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr1_-_173886401 0.390 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr1_+_29213569 0.388 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr11_+_47270433 0.385 NM_001130102
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr6_+_89790412 0.383 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr16_+_691827 0.383 NM_138418
FAM195A
family with sequence similarity 195, member A
chr11_-_63933204 0.378 MACROD1
MACRO domain containing 1
chr8_-_127570710 0.373 NM_174911
FAM84B
family with sequence similarity 84, member B
chr6_-_34360098 0.366 NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr6_+_89790464 0.357 PNRC1
proline-rich nuclear receptor coactivator 1
chr10_+_118187381 0.354 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr8_-_100905910 0.347 COX6C
cytochrome c oxidase subunit VIc
chr16_+_691901 0.345 FAM195A
family with sequence similarity 195, member A
chr1_+_6094342 0.340 NM_001199860
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_-_20126368 0.331 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chr16_+_3115312 0.323 NM_001012631
NM_001012633
NM_001012718
NM_004221
IL32



interleukin 32



chr7_+_129008044 0.322 AHCYL2
adenosylhomocysteinase-like 2
chr9_-_100954883 0.314 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr3_+_179322572 0.314 NM_001199957
NM_001199958
NM_002492
NDUFB5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa


chr18_-_74207145 0.313 NM_014643
ZNF516
zinc finger protein 516
chr8_-_127570465 0.312 FAM84B
family with sequence similarity 84, member B
chr5_-_148034089 0.311 HTR4
5-hydroxytryptamine (serotonin) receptor 4
chr1_+_65210724 0.308 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr2_-_176046120 0.302 NM_001002258
NM_001190329
NM_001689
ATP5G3


ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)


chr14_-_103989195 0.299 NM_001823
CKB
creatine kinase, brain
chr9_+_130965666 0.298 DNM1
dynamin 1
chr8_+_86376130 0.293 NM_000067
CA2
carbonic anhydrase II
chr20_-_46415277 0.287 NM_001161841
NM_198596
SULF2

sulfatase 2

chr20_-_1373571 0.286 FKBP1A
FK506 binding protein 1A, 12kDa
chr19_-_55973048 0.284 NM_001136201
NM_001136202
NM_024710
ISOC2


isochorismatase domain containing 2


chr19_-_3062191 0.275 NM_001130
NM_198970
AES

amino-terminal enhancer of split

chr5_+_176875325 0.273 NM_001174102
PRR7
proline rich 7 (synaptic)
chr1_+_33231260 0.272 KIAA1522
KIAA1522
chr3_-_121379757 0.271 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_19217384 0.270 NM_001161504
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr3_-_27763784 0.268 NM_005442
EOMES
eomesodermin
chr16_-_66952729 0.267 NM_001204744
NM_001204745
NM_001204746
NM_004062
CDH16



cadherin 16, KSP-cadherin



chr4_-_159094163 0.267 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr5_+_175084984 0.267 NM_001131055
HRH2
histamine receptor H2
chr1_+_33231227 0.262 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chrX_-_7895764 0.262 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr9_-_37904331 0.259 NM_033412
MCART1
mitochondrial carrier triple repeat 1
chr22_-_24110054 0.255 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr3_-_38691118 0.252 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr3_-_50649080 0.252 CISH
cytokine inducible SH2-containing protein
chr22_-_24316602 0.249 NM_001084392
DDT
D-dopachrome tautomerase
chr11_+_67033889 0.249 NM_001619
ADRBK1
adrenergic, beta, receptor kinase 1
chr22_+_20105076 0.249 RANBP1
RAN binding protein 1
chr19_+_1407750 0.248 DAZAP1
DAZ associated protein 1
chr11_-_63993340 0.248 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr11_-_63993562 0.247 NM_001033678
NM_001160389
NM_001160390
NM_001160392
NM_031472
TRPT1




tRNA phosphotransferase 1




chr19_-_39443326 0.246 NM_148169
FBXO17
F-box protein 17
chr11_+_67033929 0.246 ADRBK1
adrenergic, beta, receptor kinase 1
chr3_+_133465098 0.244 TF
transferrin
chr1_-_246580710 0.244 NM_022743
SMYD3
SET and MYND domain containing 3
chr6_+_43149925 0.242 CUL9
cullin 9
chr22_+_20105068 0.240 RANBP1
RAN binding protein 1
chr1_+_46769336 0.240 NM_006004
UQCRH
ubiquinol-cytochrome c reductase hinge protein
chr20_-_3748355 0.236 NM_001039140
C20orf27
chromosome 20 open reading frame 27
chr11_+_118272103 0.236 NM_006476
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr22_+_24309025 0.236 NM_001084393
DDTL
D-dopachrome tautomerase-like
chr19_-_55972997 0.236 ISOC2
isochorismatase domain containing 2
chr1_+_32716839 0.231 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr10_+_81107242 0.224 PPIF
peptidylprolyl isomerase F
chr3_-_51996855 0.222 NM_033010
PCBP4
poly(rC) binding protein 4
chr19_-_55972935 0.220 ISOC2
isochorismatase domain containing 2
chr19_-_3062911 0.219 NM_198969
AES
amino-terminal enhancer of split
chr22_+_20105145 0.219 RANBP1
RAN binding protein 1
chr6_+_125475334 0.219 NM_001003395
TPD52L1
tumor protein D52-like 1
chr22_+_32150002 0.218 NM_001007188
NM_001242896
NM_014662
DEPDC5


DEP domain containing 5


chr19_-_2328566 0.216 NM_016199
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_-_1877140 0.216 NM_001040427
NM_005326
HAGH

hydroxyacylglutathione hydrolase

chr22_+_20105095 0.216 RANBP1
RAN binding protein 1
chr5_-_140027167 0.214 NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr22_+_32149962 0.213 DEPDC5
DEP domain containing 5
chr6_-_33547833 0.213 BAK1
BCL2-antagonist/killer 1
chr1_-_204459445 0.212 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr8_+_99439249 0.211 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr11_+_65769956 0.210 BANF1
barrier to autointegration factor 1
chr15_+_65204053 0.209 NM_182703
ANKDD1A
ankyrin repeat and death domain containing 1A
chr19_+_54606141 0.209 NM_004542
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr17_-_8066254 0.209 NM_014232
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_+_153388999 0.205 NM_176823
S100A7A
S100 calcium binding protein A7A
chr10_-_91404901 0.203 PANK1
pantothenate kinase 1
chr3_+_184055275 0.202 NM_144635
FAM131A
family with sequence similarity 131, member A
chr10_+_81107259 0.202 PPIF
peptidylprolyl isomerase F
chr22_+_20104810 0.201 NM_002882
RANBP1
RAN binding protein 1
chr7_-_139876718 0.200 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr22_+_32149936 0.200 NM_001242897
DEPDC5
DEP domain containing 5
chr4_-_15939949 0.199 FGFBP1
fibroblast growth factor binding protein 1
chr5_-_156536185 0.199 NM_032782
HAVCR2
hepatitis A virus cellular receptor 2
chr1_-_27732069 0.198 WASF2
WAS protein family, member 2
chr12_-_77272767 0.198 NM_001321
CSRP2
cysteine and glycine-rich protein 2
chr2_+_238875689 0.197 UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr8_-_100905865 0.197 COX6C
cytochrome c oxidase subunit VIc
chr11_-_18747718 0.196 NM_173588
IGSF22
immunoglobulin superfamily, member 22
chr2_+_182850550 0.195 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr4_+_24797203 0.194 SOD3
superoxide dismutase 3, extracellular
chr6_+_26251826 0.194 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr9_-_130890007 0.194 PTGES2
prostaglandin E synthase 2
chr9_-_130890026 0.194 PTGES2
prostaglandin E synthase 2
chr15_-_74753490 0.194 NM_032907
NM_201265
UBL7

ubiquitin-like 7 (bone marrow stromal cell-derived)

chr9_-_130889965 0.193 PTGES2
prostaglandin E synthase 2
chr4_+_24797084 0.192 NM_003102
SOD3
superoxide dismutase 3, extracellular
chr2_+_219135114 0.192 NM_001077399
NM_015488
PNKD

paroxysmal nonkinesigenic dyskinesia

chr1_+_159557615 0.191 NM_001639
APCS
amyloid P component, serum
chr12_+_133067156 0.190 NM_001142641
FBRSL1
fibrosin-like 1
chr11_+_65769886 0.189 BANF1
barrier to autointegration factor 1
chr14_-_103988829 0.189 CKB
creatine kinase, brain
chr12_+_51632654 0.186 DAZAP2
DAZ associated protein 2
chr11_+_63993720 0.186 NM_001128612
NM_001128613
NM_032344
NUDT22


nudix (nucleoside diphosphate linked moiety X)-type motif 22


chr9_-_130679210 0.185 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr17_+_79679370 0.185 NM_012140
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr5_+_167718485 0.184 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr12_+_51632589 0.183 DAZAP2
DAZ associated protein 2
chr9_-_117150217 0.183 AKNA
AT-hook transcription factor
chr11_-_111957417 0.181 NM_012459
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr7_+_45614179 0.180 ADCY1
adenylate cyclase 1 (brain)
chr3_-_71778268 0.177 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr9_-_130889993 0.177 PTGES2
prostaglandin E synthase 2
chr20_-_633844 0.176 NM_080725
SRXN1
sulfiredoxin 1
chr1_+_236558715 0.176 NM_080738
EDARADD
EDAR-associated death domain
chr5_+_85913762 0.175 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr1_+_228270802 0.174 NM_001024227
NM_001024228
ARF1

ADP-ribosylation factor 1

chr8_+_120220554 0.174 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr1_+_16083132 0.174 FBLIM1
filamin binding LIM protein 1
chr4_-_140216951 0.174 NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_+_15052298 0.174 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chrX_+_154255063 0.171 NM_023934
FUNDC2
FUN14 domain containing 2
chr1_-_205719340 0.171 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_-_74374998 0.170 NM_001035505
NM_212552
BOLA3

bolA homolog 3 (E. coli)

chr9_-_117156684 0.170 NM_030767
AKNA
AT-hook transcription factor
chr7_+_56032065 0.170 NM_001202469
NM_001483
GBAS

glioblastoma amplified sequence

chr9_-_4742042 0.169 NM_001199853
AK3
adenylate kinase 3
chr1_+_24829299 0.168 NM_001251977
NM_001251981
NM_001251983
NM_013441
RCAN3



RCAN family member 3



chr10_-_105156186 0.167 NM_001206426
NM_001206427
NM_032747
USMG5


up-regulated during skeletal muscle growth 5 homolog (mouse)


chr16_-_15149827 0.167 NM_173474
NTAN1
N-terminal asparagine amidase
chr1_-_173886464 0.167 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chrX_+_23801431 0.166 SAT1
spermidine/spermine N1-acetyltransferase 1
chr8_-_131028674 0.165 FAM49B
family with sequence similarity 49, member B
chr3_+_158288952 0.165 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr19_-_55668956 0.165 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr15_+_78441737 0.165 IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr20_-_633808 0.164 SRXN1
sulfiredoxin 1
chr8_+_124428964 0.164 NM_018024
WDYHV1
WDYHV motif containing 1
chr15_-_91475653 0.163 NM_198527
HDDC3
HD domain containing 3
chr19_+_1383898 0.163 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr22_+_44395090 0.163 NM_001003828
PARVB
parvin, beta
chr15_-_76352068 0.163 NRG4
neuregulin 4
chr3_+_159557649 0.162 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr17_+_13972718 0.162 NM_001303
COX10
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
chr14_+_75898836 0.162 NM_001135049
JDP2
Jun dimerization protein 2
chr9_-_112191105 0.161 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chrX_-_15511358 0.160 PIR
pirin (iron-binding nuclear protein)
chr10_-_76995685 0.160 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr6_+_43149905 0.159 NM_015089
CUL9
cullin 9
chr1_+_152881022 0.159 NM_005547
IVL
involucrin
chr6_-_34664587 0.159 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr9_-_4741798 0.158 NM_001199855
AK3
adenylate kinase 3
chr16_+_21716283 0.158 NM_170664
OTOA
otoancorin
chr16_+_77756388 0.158 NM_001105663
NM_001243657
NM_001243660
NM_001243661
NUDT7



nudix (nucleoside diphosphate linked moiety X)-type motif 7



chr16_+_68679198 0.158 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr17_+_13972841 0.157 COX10
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
chr6_-_34664517 0.156 C6orf106
chromosome 6 open reading frame 106
chrX_-_21776158 0.156 NM_014332
SMPX
small muscle protein, X-linked
chr7_+_129007942 0.155 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr16_+_3115611 0.155 NM_001012635
IL32
interleukin 32
chr12_+_109915461 0.154 UBE3B
ubiquitin protein ligase E3B
chr19_+_1383904 0.154 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr16_+_776957 0.154 NM_032304
HAGHL
hydroxyacylglutathione hydrolase-like
chr9_+_130965668 0.154 DNM1
dynamin 1
chr1_-_33502464 0.153 AK2
adenylate kinase 2
chr18_-_44497307 0.153 NM_004671
NM_173206
PIAS2

protein inhibitor of activated STAT, 2

chr14_+_42076763 0.152 NM_152447
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chrY_-_1460901 0.150 NM_001636
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr2_-_74667553 0.149 NM_001015056
NM_033046
RTKN

rhotekin

chr15_-_66790068 0.149 NM_006049
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr10_-_120938276 0.148 PRDX3
peroxiredoxin 3
chr15_-_65715385 0.148 NM_020962
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr12_+_51632620 0.147 DAZAP2
DAZ associated protein 2
chr9_+_130965608 0.147 NM_001005336
NM_004408
DNM1

dynamin 1

chr19_+_1383877 0.147 NM_024407
NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr6_+_43968303 0.146 NM_001171992
NM_153246
C6orf223

chromosome 6 open reading frame 223

chr2_-_172967627 0.146 DLX2
distal-less homeobox 2
chr19_+_2249112 0.145 NM_000479
AMH
anti-Mullerian hormone
chrX_+_106161589 0.145 NM_001171095
CLDN2
claudin 2
chr1_-_202927699 0.145 NM_001127687
ADIPOR1
adiponectin receptor 1
chrX_-_134185978 0.145 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
6.02 1.17e-16 GO:0045333 cellular respiration
6.93 2.36e-16 GO:0022904 respiratory electron transport chain
3.77 5.40e-13 GO:0015980 energy derivation by oxidation of organic compounds
3.19 2.28e-12 GO:0006091 generation of precursor metabolites and energy
4.98 1.63e-11 GO:0022900 electron transport chain
2.20 1.09e-09 GO:0055114 oxidation-reduction process
6.70 3.20e-07 GO:0006119 oxidative phosphorylation
7.03 4.91e-07 GO:0042773 ATP synthesis coupled electron transport
7.03 4.91e-07 GO:0042775 mitochondrial ATP synthesis coupled electron transport
8.20 5.78e-07 GO:0009060 aerobic respiration
1.24 5.48e-04 GO:0044237 cellular metabolic process
1.12 1.92e-03 GO:0009987 cellular process
5.90 2.40e-03 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
1.51 2.75e-03 GO:0044281 small molecule metabolic process
1.38 2.79e-03 GO:0006810 transport
4.02 3.21e-03 GO:0006839 mitochondrial transport
6.96 4.81e-03 GO:0046356 acetyl-CoA catabolic process
1.36 7.50e-03 GO:0051234 establishment of localization
19.32 1.37e-02 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
1.19 1.86e-02 GO:0008152 metabolic process
6.00 1.96e-02 GO:0009109 coenzyme catabolic process
6.44 3.40e-02 GO:0006099 tricarboxylic acid cycle
7.52 3.63e-02 GO:0015985 energy coupled proton transport, down electrochemical gradient
7.52 3.63e-02 GO:0015986 ATP synthesis coupled proton transport
2.65 3.78e-02 GO:0006732 coenzyme metabolic process
2.56 4.32e-02 GO:0006979 response to oxidative stress

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.49 1.63e-25 GO:0005739 mitochondrion
3.13 4.32e-23 GO:0044429 mitochondrial part
4.35 1.67e-22 GO:0005743 mitochondrial inner membrane
3.56 2.10e-21 GO:0005740 mitochondrial envelope
3.63 2.20e-21 GO:0031966 mitochondrial membrane
3.98 3.05e-20 GO:0019866 organelle inner membrane
6.12 1.13e-17 GO:0044455 mitochondrial membrane part
2.60 1.64e-14 GO:0031967 organelle envelope
2.56 5.08e-14 GO:0031975 envelope
7.03 2.97e-12 GO:0070469 respiratory chain
6.97 4.77e-11 GO:0005746 mitochondrial respiratory chain
1.34 3.92e-10 GO:0044444 cytoplasmic part
1.24 3.72e-09 GO:0005737 cytoplasm
5.95 1.33e-04 GO:0005747 mitochondrial respiratory chain complex I
5.95 1.33e-04 GO:0030964 NADH dehydrogenase complex
5.95 1.33e-04 GO:0045271 respiratory chain complex I
2.47 7.93e-04 GO:0005759 mitochondrial matrix
10.54 2.49e-03 GO:0005744 mitochondrial inner membrane presequence translocase complex
19.32 2.53e-03 GO:0005749 mitochondrial respiratory chain complex II
19.32 2.53e-03 GO:0045257 succinate dehydrogenase complex (ubiquinone)
19.32 2.53e-03 GO:0045273 respiratory chain complex II
19.32 2.53e-03 GO:0045281 succinate dehydrogenase complex
19.32 2.53e-03 GO:0045283 fumarate reductase complex
1.41 3.59e-03 GO:0031090 organelle membrane
7.96 4.28e-03 GO:0005753 mitochondrial proton-transporting ATP synthase complex
1.42 4.29e-03 GO:0005829 cytosol
7.12 1.01e-02 GO:0045259 proton-transporting ATP synthase complex
1.09 4.03e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.05 3.86e-06 GO:0016491 oxidoreductase activity
5.39 6.77e-04 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
5.75 9.43e-04 GO:0003954 NADH dehydrogenase activity
5.75 9.43e-04 GO:0008137 NADH dehydrogenase (ubiquinone) activity
5.75 9.43e-04 GO:0050136 NADH dehydrogenase (quinone) activity
3.59 1.21e-03 GO:0015078 hydrogen ion transmembrane transporter activity
3.82 1.88e-03 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
1.24 2.10e-03 GO:0003824 catalytic activity
19.32 3.98e-03 GO:0000104 succinate dehydrogenase activity
2.62 1.33e-02 GO:0009055 electron carrier activity
15.46 1.91e-02 GO:0008048 calcium sensitive guanylate cyclase activator activity
1.16 4.73e-02 GO:0005515 protein binding