Motif ID: ETS1,2.p2

Z-value: 1.750


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS1chr11_-_128391888-0.462.5e-01Click!
ETS2chr21_+_401778470.108.1e-01Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_15939949 3.300 FGFBP1
fibroblast growth factor binding protein 1
chr4_-_15940362 2.609 NM_005130
 FGFBP1
fibroblast growth factor binding protein 1
chr10_-_105845619 2.438 NM_000494
 COL17A1
collagen, type XVII, alpha 1
chr13_-_20805371 2.372 NM_006783
 GJB6
gap junction protein, beta 6, 30kDa
chr10_-_105845556 2.084 COL17A1
collagen, type XVII, alpha 1
chr10_-_88717319 1.876 NM_024756
 MMRN2
multimerin 2
chr14_-_94856926 1.485 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
 SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr2_-_46384 1.434 NM_001077710
 FAM110C
family with sequence similarity 110, member C
chr15_+_41136622 1.322 NM_001032367
 SPINT1
serine peptidase inhibitor, Kunitz type 1
chr8_+_56792392 1.316 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr2_-_113542970 1.302 NM_000575
 IL1A
interleukin 1, alpha
chr22_+_45098091 1.302 NM_181334
 PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr8_+_56792345 1.268 NM_001111097
NM_002350
 LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr15_+_43885251 1.205 NM_020990
 CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr1_-_201368716 1.157 LAD1
ladinin 1
chr16_+_57653909 1.156 NM_001145770
NM_005682
 GPR56

G protein-coupled receptor 56

chr11_+_1861431 1.148 NM_001145841
 TNNI2
troponin I type 2 (skeletal, fast)
chr2_-_70781146 1.114 NM_001099691
NM_003236
 TGFA

transforming growth factor, alpha

chr7_-_143105897 1.089 NM_005232
 EPHA1
EPH receptor A1
chr8_+_56792399 1.080 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.12 4.14e-02 GO:0030098 lymphocyte differentiation
1.89 9.07e-03 GO:0051251 positive regulation of lymphocyte activation
1.87 7.38e-03 GO:0002696 positive regulation of leukocyte activation
1.84 1.30e-02 GO:0050867 positive regulation of cell activation
1.58 5.23e-04 GO:0001775 cell activation
1.57 3.73e-03 GO:0002684 positive regulation of immune system process
1.44 2.16e-03 GO:0006955 immune response
1.36 3.28e-04 GO:0002376 immune system process
1.20 2.65e-02 GO:0044267 cellular protein metabolic process
1.19 1.86e-05 GO:0044260 cellular macromolecule metabolic process
1.17 6.48e-05 GO:0043170 macromolecule metabolic process
1.08 5.02e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.44 2.90e-02 GO:0000139 Golgi membrane
1.41 3.08e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.41 3.19e-03 GO:0005789 endoplasmic reticulum membrane
1.40 1.53e-03 GO:0044432 endoplasmic reticulum part
1.38 3.68e-02 GO:0044431 Golgi apparatus part
1.28 2.35e-02 GO:0005783 endoplasmic reticulum
1.24 1.59e-02 GO:0012505 endomembrane system
1.21 1.11e-02 GO:0031090 organelle membrane
1.13 1.28e-03 GO:0044446 intracellular organelle part
1.12 1.22e-03 GO:0044422 organelle part
1.09 2.16e-03 GO:0005737 cytoplasm
1.06 1.16e-02 GO:0044424 intracellular part
1.05 2.28e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.73 4.93e-02 GO:0016758 transferase activity, transferring hexosyl groups
1.13 5.56e-06 GO:0005515 protein binding