Motif ID: FEV.p2

Z-value: 1.324


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2198502730.363.8e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_43885251 2.759 NM_020990
 CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr4_+_40198526 2.381 NM_004310
 RHOH
ras homolog gene family, member H
chr8_+_124194873 1.752 FAM83A
family with sequence similarity 83, member A
chr8_+_124194751 1.442 NM_032899
NM_207006
 FAM83A

family with sequence similarity 83, member A

chr11_+_130029663 1.405 NM_021978
 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr11_+_130029699 1.310 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr19_+_35739838 1.294 LSR
lipolysis stimulated lipoprotein receptor
chr11_+_130029773 1.286 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr1_-_183559669 1.178 NM_000433
NM_001190789
NM_001190794
 NCF2


neutrophil cytosolic factor 2


chr18_+_21452981 1.171 NM_000227
NM_001127718
 LAMA3

laminin, alpha 3

chr19_-_54676813 1.164 NM_001145303
NM_144686
 TMC4

transmembrane channel-like 4

chr19_+_35739778 1.156 LSR
lipolysis stimulated lipoprotein receptor
chr2_+_182321618 1.136 NM_000885
 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr15_+_41136622 1.132 NM_001032367
 SPINT1
serine peptidase inhibitor, Kunitz type 1
chr7_+_26400503 1.113 NM_001199837
 SNX10
sorting nexin 10
chr3_-_151034514 1.108 NM_023915
 GPR87
G protein-coupled receptor 87
chr14_+_65171149 1.088 NM_015549
 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr7_+_18548899 1.086 NM_001204147
NM_001204148
 HDAC9

histone deacetylase 9

chr9_+_93564063 1.037 SYK
spleen tyrosine kinase
chr14_+_65171243 1.028 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
1.92 2.19e-03 GO:0042254 ribosome biogenesis
1.90 8.74e-04 GO:0050870 positive regulation of T cell activation
1.88 1.27e-02 GO:0042110 T cell activation
1.86 1.70e-04 GO:0051251 positive regulation of lymphocyte activation
1.79 7.28e-04 GO:0002696 positive regulation of leukocyte activation
1.78 1.16e-05 GO:0045321 leukocyte activation
1.78 6.66e-04 GO:0050867 positive regulation of cell activation
1.73 2.07e-03 GO:0022613 ribonucleoprotein complex biogenesis
1.72 2.89e-03 GO:0046649 lymphocyte activation
1.71 1.96e-03 GO:0071843 cellular component biogenesis at cellular level
1.67 3.91e-03 GO:0051249 regulation of lymphocyte activation
1.67 4.31e-02 GO:0050863 regulation of T cell activation
1.66 1.90e-03 GO:0002694 regulation of leukocyte activation
1.63 2.87e-03 GO:0050865 regulation of cell activation
1.46 1.30e-03 GO:0001775 cell activation
1.46 5.03e-03 GO:0002684 positive regulation of immune system process
1.45 3.71e-02 GO:0006397 mRNA processing
1.43 2.54e-02 GO:0050776 regulation of immune response
1.42 4.68e-05 GO:0006955 immune response
1.40 1.46e-02 GO:0016071 mRNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.84 4.26e-02 GO:0042470 melanosome
1.84 4.26e-02 GO:0048770 pigment granule
1.50 1.28e-05 GO:0005730 nucleolus
1.38 1.74e-14 GO:0031981 nuclear lumen
1.38 8.69e-10 GO:0005654 nucleoplasm
1.38 1.43e-04 GO:0044451 nucleoplasm part
1.34 4.16e-14 GO:0044428 nuclear part
1.33 1.42e-13 GO:0070013 intracellular organelle lumen
1.32 1.74e-13 GO:0043233 organelle lumen
1.32 2.35e-13 GO:0031974 membrane-enclosed lumen
1.22 4.58e-07 GO:0043228 non-membrane-bounded organelle
1.22 4.58e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.18 9.59e-03 GO:0005829 cytosol
1.14 7.57e-08 GO:0044446 intracellular organelle part
1.14 7.78e-08 GO:0044422 organelle part
1.13 2.63e-06 GO:0005634 nucleus
1.08 2.00e-09 GO:0044424 intracellular part
1.08 3.98e-05 GO:0043227 membrane-bounded organelle
1.08 4.90e-05 GO:0043231 intracellular membrane-bounded organelle
1.08 1.04e-04 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.32 1.97e-03 GO:0003723 RNA binding
1.29 4.68e-02 GO:0019899 enzyme binding
1.19 1.88e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.18 1.55e-02 GO:0017076 purine nucleotide binding
1.18 1.82e-02 GO:0032553 ribonucleotide binding
1.18 1.82e-02 GO:0032555 purine ribonucleotide binding
1.17 6.66e-03 GO:0000166 nucleotide binding
1.14 1.11e-12 GO:0005515 protein binding
1.05 6.53e-04 GO:0005488 binding