Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.198


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXF2chr6_+_1390068-0.275.2e-01Click!
FOXF1chr16_+_865441040.265.3e-01Click!
FOXJ1chr17_-_74137370-0.265.4e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_209602164 1.730 NM_001104548
MIR205HG
MIR205 host gene (non-protein coding)
chr1_+_86889768 1.615 NM_006536
CLCA2
chloride channel accessory 2
chr3_+_136676706 1.582 NM_144717
IL20RB
interleukin 20 receptor beta
chr18_+_61254533 1.508 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr8_-_134309448 1.473 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr5_+_166711842 1.463 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr2_-_165424993 1.442 GRB14
growth factor receptor-bound protein 14
chr11_-_108464344 1.391 NM_015065
EXPH5
exophilin 5
chr12_-_53343607 1.372 KRT8
keratin 8
chr1_+_153003677 1.299 NM_003125
SPRR1B
small proline-rich protein 1B
chr3_+_189349215 1.233 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr20_+_58630965 1.136 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr8_-_15095791 1.025 NM_139167
SGCZ
sarcoglycan, zeta
chr10_+_118187381 1.003 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr11_+_34654010 0.985 NM_001206616
EHF
ets homologous factor
chr17_+_9745847 0.932 GLP2R
glucagon-like peptide 2 receptor
chr1_-_207205996 0.928 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr15_+_40509628 0.921 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr10_-_105845619 0.910 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr1_-_28503454 0.883 NM_000952
NM_001164723
PTAFR

platelet-activating factor receptor

chr10_+_111985628 0.832 NM_005962
MXI1
MAX interactor 1
chr2_-_215896809 0.816 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_+_152486977 0.809 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr1_+_28261503 0.807 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr10_-_105845556 0.782 COL17A1
collagen, type XVII, alpha 1
chr1_+_46646199 0.780 TSPAN1
tetraspanin 1
chr1_-_24469571 0.779 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr4_-_123542165 0.742 NM_001207006
NM_021803
IL21

interleukin 21

chr18_-_74844710 0.727 MBP
myelin basic protein
chr5_+_140220811 0.722 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr17_+_35294771 0.696 NM_005568
LHX1
LIM homeobox 1
chr1_-_186649421 0.685 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr4_+_100737980 0.683 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr5_-_142065991 0.680 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr10_-_45474210 0.672 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr10_+_111969988 0.671 NM_001008541
MXI1
MAX interactor 1
chr8_-_80993009 0.659 NM_001025252
TPD52
tumor protein D52
chr5_-_142065586 0.657 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr1_+_43735664 0.606 NM_144626
TMEM125
transmembrane protein 125
chr18_-_53068755 0.593 TCF4
transcription factor 4
chr1_+_172389827 0.585 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr20_-_1309809 0.581 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr6_+_112375277 0.576 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr5_+_140186658 0.571 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr5_+_145316120 0.562 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr2_+_86947429 0.560 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr1_+_81771844 0.536 LPHN2
latrophilin 2
chr14_-_21566728 0.535 NM_016423
ZNF219
zinc finger protein 219
chr1_+_220960038 0.522 NM_022746
MARC1
mitochondrial amidoxime reducing component 1
chr17_+_8924822 0.520 NM_004822
NTN1
netrin 1
chr5_+_36606667 0.518 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_120079423 0.517 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr12_-_86229981 0.509 RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr7_+_26400503 0.505 NM_001199837
SNX10
sorting nexin 10
chr1_+_227127993 0.494 ADCK3
aarF domain containing kinase 3
chr3_-_190167597 0.491 NM_207316
TMEM207
transmembrane protein 207
chr10_-_116418056 0.490 NM_002313
ABLIM1
actin binding LIM protein 1
chr18_-_74844762 0.484 NM_001025100
NM_001025101
MBP

myelin basic protein

chr2_+_86947570 0.480 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr11_-_115375065 0.480 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr1_+_227127959 0.478 ADCK3
aarF domain containing kinase 3
chr12_-_31479038 0.477 FAM60A
family with sequence similarity 60, member A
chr22_+_21128378 0.469 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr11_-_102668892 0.465 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr2_-_161056762 0.465 ITGB6
integrin, beta 6
chr7_+_129906702 0.463 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr15_-_40600065 0.460 PLCB2
phospholipase C, beta 2
chr11_-_102668822 0.459 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr2_+_86947387 0.456 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr19_-_33360641 0.451 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr4_-_89978117 0.441 NM_014883
FAM13A
family with sequence similarity 13, member A
chr7_+_150102376 0.441


chr13_-_41240607 0.439 NM_002015
FOXO1
forkhead box O1
chr14_-_100070442 0.437 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr19_+_18496966 0.434 NM_004864
GDF15
growth differentiation factor 15
chr20_-_22566092 0.434 NM_153675
FOXA2
forkhead box A2
chr10_-_123356158 0.422 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr22_+_37309618 0.422 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_207095198 0.416 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr1_+_227127999 0.411 ADCK3
aarF domain containing kinase 3
chr7_-_139763520 0.408 NM_022750
PARP12
poly (ADP-ribose) polymerase family, member 12
chr8_+_124194873 0.407 FAM83A
family with sequence similarity 83, member A
chr9_-_124984018 0.406 NM_001242335
LHX6
LIM homeobox 6
chr3_-_165555167 0.405 BCHE
butyrylcholinesterase
chr8_-_110655418 0.404 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr21_+_30517897 0.403 C21orf7
chromosome 21 open reading frame 7
chr4_+_146403955 0.402 NM_001003688
SMAD1
SMAD family member 1
chr5_+_68788118 0.402 NM_002538
OCLN
occludin
chr11_-_34535302 0.400 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr12_-_31479084 0.397 FAM60A
family with sequence similarity 60, member A
chr12_-_31479120 0.395 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr1_+_47533046 0.395 NM_178134
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr8_-_28243941 0.393 NM_018660
ZNF395
zinc finger protein 395
chr1_+_13911966 0.392 NM_001006624
NM_001006625
PDPN

podoplanin

chr7_-_140624280 0.392 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr17_-_39942937 0.390 NM_002230
NM_021991
JUP

junction plakoglobin

chr18_-_53071225 0.387 NM_001243232
TCF4
transcription factor 4
chr15_-_40599974 0.387 PLCB2
phospholipase C, beta 2
chr1_+_82266081 0.386 NM_012302
LPHN2
latrophilin 2
chr6_-_32784727 0.381 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr14_-_21493122 0.380 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr12_+_13043955 0.374 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr9_-_135819953 0.372 TSC1
tuberous sclerosis 1
chr5_+_68800003 0.372 NM_001205255
OCLN
occludin
chr18_+_60382617 0.366 NM_194449
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr5_-_36301999 0.364 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr20_-_43883183 0.358 NM_003064
SLPI
secretory leukocyte peptidase inhibitor
chr3_-_165555252 0.358 NM_000055
BCHE
butyrylcholinesterase
chr18_+_61575203 0.356 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chrX_-_33357725 0.356 NM_000109
DMD
dystrophin
chr6_-_29012951 0.349 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr17_+_26662547 0.348 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_+_220701547 0.348 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr2_+_75059781 0.346 NM_000189
HK2
hexokinase 2
chr22_+_45148437 0.345 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr4_-_87028805 0.340 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr10_+_71561687 0.339 COL13A1
collagen, type XIII, alpha 1
chr6_+_121756744 0.337 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr2_-_165478357 0.334 NM_004490
GRB14
growth factor receptor-bound protein 14
chr13_+_97874704 0.333 MBNL2
muscleblind-like 2 (Drosophila)
chr4_-_153273683 0.329 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr8_+_75736771 0.321 NM_015886
PI15
peptidase inhibitor 15
chr11_-_114466397 0.321 FAM55D
family with sequence similarity 55, member D
chr7_+_134233848 0.315 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr6_-_105627857 0.314 NM_022361
POPDC3
popeye domain containing 3
chrX_+_70315637 0.309 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr6_-_134373618 0.307 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr11_-_104769396 0.305 NM_001191016
CASP12
caspase 12 (gene/pseudogene)
chr4_-_87374282 0.302 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr2_+_113885137 0.299 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr6_+_84562984 0.297 NM_001009994
RIPPLY2
ripply2 homolog (zebrafish)
chr17_-_54893249 0.296 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr17_-_39023461 0.296 NM_000223
KRT12
keratin 12
chr8_+_99956630 0.294 NM_001142462
NM_053001
OSR2

odd-skipped related 2 (Drosophila)

chr1_+_220701800 0.294 MARK1
MAP/microtubule affinity-regulating kinase 1
chr11_-_63933204 0.289 MACROD1
MACRO domain containing 1
chr19_-_18654280 0.289 FKBP8
FK506 binding protein 8, 38kDa
chr4_-_155511838 0.286 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr2_-_31637553 0.284 XDH
xanthine dehydrogenase
chr15_+_74907334 0.283 NM_001130028
CLK3
CDC-like kinase 3
chr17_+_39382878 0.283 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr17_+_67410825 0.278 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr8_-_131028646 0.277 FAM49B
family with sequence similarity 49, member B
chr13_-_86373328 0.274 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr8_-_131028674 0.270 FAM49B
family with sequence similarity 49, member B
chr3_+_112931374 0.268 NM_033254
BOC
Boc homolog (mouse)
chr13_-_46756326 0.267 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_-_46756291 0.266 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_+_80390757 0.265 NM_001242919
ZFAND6
zinc finger, AN1-type domain 6
chrX_-_117119282 0.265 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr2_-_161056573 0.264 NM_000888
ITGB6
integrin, beta 6
chr1_-_1356823 0.264 NM_001145210
NM_001243535
NM_001243536
ANKRD65


ankyrin repeat domain 65


chr10_+_123923104 0.259 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr1_-_161147757 0.258 NM_001199873
NM_001199874
NM_003779
B4GALT3


UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3


chr6_+_26501448 0.257 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr2_+_113885145 0.256 IL1RN
interleukin 1 receptor antagonist
chr7_-_25268057 0.255 NM_022150
NPVF
neuropeptide VF precursor
chr12_+_20963637 0.252 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_-_93342706 0.252 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr19_-_51531283 0.251 NM_001167605
NM_006853
KLK11

kallikrein-related peptidase 11

chr5_+_40841296 0.249 NM_032587
CARD6
caspase recruitment domain family, member 6
chr9_-_117568292 0.249 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr5_+_54398473 0.248 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr12_-_71031174 0.245 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_-_85108202 0.245 C2orf89
chromosome 2 open reading frame 89
chr9_-_3223007 0.244


chr14_-_21567069 0.243 NM_001101672
ZNF219
zinc finger protein 219
chr17_-_39165343 0.242 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr13_-_46756295 0.239 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr8_+_107738239 0.237 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr17_-_76124791 0.236 NM_001127198
TMC6
transmembrane channel-like 6
chr3_+_98451537 0.235 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr20_+_62795773 0.235 MYT1
myelin transcription factor 1
chr2_-_71454200 0.232 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr12_+_9142136 0.230 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr14_+_74551655 0.225 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr15_-_67814131 0.220 LOC100506686
uncharacterized LOC100506686
chrX_+_135614310 0.219 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr10_-_118680978 0.219 KIAA1598
KIAA1598
chr8_+_67344717 0.217 NM_144650
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr20_-_44563684 0.217 FLJ40606
uncharacterized LOC643549
chr11_-_114466471 0.217 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr7_+_86273219 0.215 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr11_-_118084073 0.213 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr2_+_33661392 0.211 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_+_9458460 0.211 PLCB4
phospholipase C, beta 4
chr5_+_140174443 0.210 NM_018905
NM_031495
PCDHA2

protocadherin alpha 2

chr1_+_227127937 0.209 NM_020247
ADCK3
aarF domain containing kinase 3
chr2_-_85108238 0.209 NM_001080824
C2orf89
chromosome 2 open reading frame 89
chr19_+_41699076 0.208 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr12_-_123201319 0.208 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr16_+_56815703 0.207 NM_001242795
NUP93
nucleoporin 93kDa
chr1_+_20915440 0.202 NM_001785
CDA
cytidine deaminase
chr2_+_196521470 0.200 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr5_+_140261792 0.199 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chrX_+_115301957 0.198 NM_000686
AGTR2
angiotensin II receptor, type 2
chr2_+_242127923 0.198 NM_001001666
NM_001001891
ANO7

anoctamin 7

chr17_-_36003454 0.198 NM_007010
DDX52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr16_+_81812897 0.197 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr19_+_15160194 0.195 NM_012114
CASP14
caspase 14, apoptosis-related cysteine peptidase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
7.93 2.52e-02 GO:0015721 bile acid and bile salt transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.39 3.86e-03 GO:0044459 plasma membrane part
1.37 1.75e-02 GO:0005576 extracellular region
1.47 3.30e-02 GO:0005887 integral to plasma membrane
1.46 4.09e-02 GO:0031226 intrinsic to plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.83 6.61e-03 GO:0004435 phosphatidylinositol phospholipase C activity
4.80 3.72e-02 GO:0004629 phospholipase C activity
3.13 4.13e-02 GO:0004867 serine-type endopeptidase inhibitor activity